摘要:
A method, computer program product and system for displaying images during the execution of an application. A developer of an application inserts application hooks at particular locations in the code of the application to be executed. An application hook could be a call to a function in a utility code where the call includes the passing of a “key name”. The called function may retrieve an image located at an image file name in a configuration file associated with the key name if such an image file exists. Presentations that demonstrate the execution of the application may be easily modified by adding, deleting or replacing images at these file names. These modifications may be made without modifying the code of the application being executed. In this manner, different images used in different presentations may be displayed to different targeted audiences without modifying the code of the executed application.
摘要:
There is disclosed the use of a compound of formula (I) wherein R1, R2, X, Y, V, W and Z are as defined in the specification, and pharmaceutically acceptable salts, enantiomers or racemates thereof, in the manufacture of a medicament, for the treatment or prophylaxis of diseases or conditions in which inhibition of nitric oxide synthase activity is beneficial. Certain novel compounds of formula (Ia) and pharmaceutically acceptable salts thereof, and enantiomers and racemates thereof are disclosed; together with processes for their preparation, compositions containing them and their use in therapy. The compounds of formulae (I) and (Ia) are inhibitors of the enzyme nitric oxide synthase and are thereby particularly useful in the treatment or prophylaxis of inflammatory disease.
摘要:
A method of forming a pot for an array of hollow fibre membranes (7) is provided, including the steps of placing the ends (6) of the fibre membranes (7) in a mould (5); forming a first layer (20) of curable resin material in a non-cured state around the fibre membrane ends (6), applying a second layer (21) of a polyurethane resin material to the first layer (20) prior to full curing of the first layer, the polyurethane resin material layer being chemically reactive with the first layer material to form an adhesive bond therebetween; at least partially curing both layers and removing the pot formed from the mould (5), wherein the second layer material is of higher flexibility than the first layer material when each layer is fully cured. Apparatus for performing the method is also disclosed.
摘要:
The invention provides methods of analyzing genes for differential relative allelic expression patterns. Haplotype blocks throughout the genomes of individuals are analyzed to identify haplotype patterns that are associated with specific differential relative allelic expression patterns. Haplotype blocks that contain associated haplotype patterns may be further investigated to identify genes or variants of genes involved in differential relative allelic expression patterns.
摘要:
The invention disclosed is a device for repairing a soft tissue defect, particularly a defect in the meniscus of a knee. The device comprises an outer wall anchor for engaging against an outside wall of the meniscus on a first side of the defect, an inner meniscal anchor engaging an inner surface of the meniscus on a second side of the defect, the inner meniscal anchor having a locking mechanism, and a suture adjustably connecting the outer wall anchor to the inner meniscal anchor. Tension on the suture pulls the defect together and the locking mechanism then locks the suture in place.
摘要:
The invention disclosed is a device for repairing a soft tissue defect, particularly a defect in the meniscus of a knee. The device comprises an outer wall anchor for engaging against an outside wall of the meniscus on a first side of the defect, an inner meniscal anchor engaging an inner surface of the meniscus on a second side of the defect, the inner meniscal anchor having a locking mechanism, and a suture adjustably connecting the outer wall anchor to the inner meniscal anchor. Tension on the suture pulls the defect together and the locking mechanism then locks the suture in place.
摘要:
The process for the production of a dimeric, biologically active Transforming Growth Factor type .beta. (TGF-.beta.)-like protein or a salt thereof, comprising refolding the denatured monomeric form of the protein in the presence of a mild detergent that permits folding of the monomeric protein into a spatial conformation, which after dimerization, is the conformation associated with the biological activity, while retaining the monomeric protein in soluble form. Mild detergents include sulfobetaines, 3-(3-chlolamidopropyl)dimethylammonio-1-propanesulfonate, 3-(3-chlolamidopropyl)dimethylammonio-2-hydroxy-1-propane-sulfonate, digitonin, cholate and deoxycholate at a concentration of about 1 to 100 mM. Compositions containing a TGF-.beta.-like protein produced according the invention can be used for the promotion and acceleration of wound healing and bone and tissue repair, cancer treatment, bone marrow protective agent, as a mediator of cardio-protection, as an anti-inflammatory or immunosuppressive agent, or as a growth regulator in mammalian cell cultures.
摘要:
Compounds of formula I, ##STR1## in which A is a 5 or 6 membered, fully unsaturated, carbocyclic or heterocyclic ring,B is a 5 or 6 membered, fully unsaturated, nitrogen containing heterocyclic ring,X is NR.sub.19, O or S,R.sub.19 is hydrogen or alkyl optionally substituted by --OCOR,n is 0 or 1,R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7, R.sub.8, R.sub.9 and R.sub.10 have various significances,R.sub.1 and R.sub.2, are hydrogen or alkyl or together with the ring carbon atoms to which they are attached, form a benzene or pyridine ring, which ring carries substituents R.sub.15, R.sub.16, R.sub.17 and R.sub.18,R.sub.15, R.sub.16, R.sub.17 and R.sub.18, have varioussignificances, with certain provisos are described.Processes for making the compounds and pharmaceutical formulations containing them, e.g. for the treatment of conditions including excess gastric acid secretion, are also described.
摘要:
In various embodiments, training objects are classified by human annotators, psychometric data characterizing the annotation of the training objects is acquired, a human-weighted loss function based at least in part on the classification data and the psychometric data is computationally derived, and one or more features of a query object are computationally classified based at least in part on the human-weighted loss function.