公开(公告)号：US20240359006A1

公开(公告)日：2024-10-31

申请号：US18648764

申请日：2024-04-29

Applicant: Northwestern University

Inventor： Timothy L. Sita

IPC: A61N1/36 ,  A61N1/04 ,  A61N1/20

CPC classification number: A61N1/36002 ,  A61N1/0408 ,  A61N1/205 ,  A61N1/36034

Abstract: Electrical modulation provides treatment of brain tumors, such as glioblastoma. An electrical stimulus may be applied to the brain of a patient with a brain tumor (e.g., primary or metastatic brain tumor in upfront, adjuvant, or recurrent treatment setting) via bitemporal and/or unitemporal electrodes. The electrical modulation acts on brain tumor networks to slow tumor growth and increase survivability of the patient. The electrical modulation also transiently permits passage of therapeutics across the blood-brain barrier. The electrical modulation also sensitizes brain tumors to radiation therapy, immunotherapy, and chemotherapy.

公开(公告)号：US20240358279A1

公开(公告)日：2024-10-31

申请号：US18771659

申请日：2024-07-12

Applicant: BLINK DEVICE LLC

Inventor： Justin HULVERSHORN ,  Karl SCHMIDT ,  Tyler HART

IPC: A61B5/11 ,  A61B5/00 ,  A61B5/24 ,  A61B5/294 ,  A61B5/296 ,  A61B5/305 ,  A61B5/388 ,  A61B5/389 ,  A61B5/395 ,  A61N1/04 ,  G16H10/60 ,  G16H50/20

CPC classification number: A61B5/1106 ,  A61B5/24 ,  A61B5/296 ,  A61B5/305 ,  A61B5/388 ,  A61B5/389 ,  A61B5/395 ,  A61B5/6824 ,  A61B5/6826 ,  A61B5/6833 ,  A61B5/685 ,  A61B5/7217 ,  A61B5/294 ,  A61B2560/0238 ,  A61B2562/0219 ,  A61N1/0456 ,  G16H10/60 ,  G16H50/20

Abstract: Neuromuscular monitoring is described that uses a novel lead assembly and a monitor that can select the appropriate electrodes on the lead assembly and calibrate the stimulation signals applied to the patient through the lead assembly. The monitoring can also set a noise floor value to reduce the likelihood of an erroneous train of four ratio.

公开(公告)号：US20240350817A1

公开(公告)日：2024-10-24

申请号：US18760311

申请日：2024-07-01

Applicant: West Affum Holdings DAC

Inventor： Joseph Leo Sullivan ,  Jaeho Kim

IPC: A61N1/39 ,  A61B5/00 ,  A61B5/352 ,  A61N1/04

CPC classification number: A61N1/3904 ,  A61N1/0484 ,  A61N1/3975 ,  A61N1/3987 ,  A61N1/3993 ,  A61B5/352 ,  A61B5/7203

Abstract: In embodiments a wearable cardioverter defibrillator (WCD) system is worn by an ambulatory patient. The WCD system analyzes an ECG signal of the patient, to determine whether or not the patient should be given an electric shock to restart their heart. If the WCD system determines that such a shock should be given, then it also determines whether or not a High Frequency (H-F) noise criterion is met by the ECG signal. If that H-F noise criterion is not met, the patient can be shocked. If, however, that H-F noise criterion is met, then the WCD system can confirm before shocking, by sensing another portion of the ECG signal, analyzing again, and so on. Thanks to the confirmation before shocking, the possibility is diminished that the ECG signal will indicate that a shock is needed falsely, due to H-F noise. This can further reduce false patient alarms, and so on.

公开(公告)号：US12122058B2

公开(公告)日：2024-10-22

申请号：US17796191

申请日：2020-11-19

Applicant: Panasonic Intellectual Property Management Co., Ltd.

Inventor： Yoshiaki Kanamori ,  Kenji Narita

IPC: B26B19/48 ,  A61N1/04 ,  A61N1/32 ,  A61N1/36

CPC classification number: B26B19/48 ,  A61N1/0428 ,  A61N1/0476 ,  A61N1/328 ,  A61N1/3603

Abstract: A beauty instrument according to the present disclosure comprises a skin electrode disposed in a head, a grip electrode disposed in a grip, a voltage application circuit for applying a voltage between the skin electrode and the grip electrode to cause a current to flow between the skin electrode and the grip electrode through a human body, and a controller that controls the voltage application circuit. The controller comprises a touch detector that detects touch of a skin surface of the human body with the skin electrode. Before the touch detector detects the touch, the voltage application circuit is controlled to apply a first voltage having a relatively high frequency, and after the touch detector detects the touch, the voltage application circuit is controlled to apply a second voltage having a relatively low frequency.

公开(公告)号：US20240342474A1

公开(公告)日：2024-10-17

申请号：US18431974

申请日：2024-02-03

Applicant: SetPoint Medical Corporation

Inventor： Jacob A. LEVINE ,  Ralph J. ZITNIK

IPC: A61N1/36 ,  A61N1/04 ,  A61N1/372 ,  A61N2/00 ,  A61N7/00 ,  G01N33/68

CPC classification number: A61N1/36053 ,  G01N33/6863 ,  G01N33/6869 ,  A61N1/0456 ,  A61N1/3606 ,  A61N1/372 ,  A61N2/006 ,  A61N2007/0026 ,  G01N2333/525 ,  G01N2333/535 ,  G01N2333/54 ,  G01N2333/5412 ,  G01N2333/5434 ,  G01N2333/545 ,  G01N2333/57 ,  G01N2800/52 ,  G01N2800/709 ,  G01N2800/7095

Abstract: Diagnostic screening tests that can be used to identify if a patient is a good candidates for an implantable vagus nerve stimulation device. One or more analyte, such as a cytokine or inflammatory molecule, can be measured from a blood sample taken prior to implantation of a vagus nerve stimulator to determine the patient's responsiveness to VNS for treatment of an inflammatory disorder.

公开(公告)号：US12115380B2

公开(公告)日：2024-10-15

申请号：US17062534

申请日：2020-10-02

Applicant: Medtronic, Inc.

Inventor： Jesse J. Pischlar ,  Kenneth C. Gardeski ,  Michael R. Leners ,  Peter B. McIntyre

IPC: A61N1/04 ,  A61N1/375 ,  A61N1/39

CPC classification number: A61N1/39622 ,  A61N1/0472 ,  A61N1/0488 ,  A61N1/37512 ,  A61N1/3754

Abstract: A medical device includes an elongated body having a proximal end and a distal end and a braided tubular body extending coaxially with the elongated body between the proximal and distal ends. The braided tubular body includes multiple cables extending helically in opposing directions in an interwoven manner. Each cable includes multiple, electrically conductive filars. In some examples, each filar includes an electrically insulating coating or layer.

公开(公告)号：US12115369B1

公开(公告)日：2024-10-15

申请号：US17894485

申请日：2022-08-24

Applicant: Orbital Research Inc.

Inventor： Frederick J. Lisy ,  Anthony Opperman ,  Matthew D. Tarler ,  Angela Lisy ,  Vincent R. Cozza

IPC: A61N1/36 ,  A61N1/04

CPC classification number: A61N1/36014 ,  A61N1/0472

Abstract: The present invention is directed to systems, devices and methods for stimulating perceived motion, and more particularly to stimulating perceived motion in three axes. The invention is further directed to stimulating such perceived motion when accompanied by visual stimuli. The invention is further directed to utilizing as few as two distinct pairs of electrodes to administer electrical stimulation to generate the perceived motion. The invention is further directed to systems, devices and methods to minimize side effects while utilizing electrical currents create the perceived motion.

公开(公告)号：US12115366B2

公开(公告)日：2024-10-15

申请号：US18178257

申请日：2023-03-03

Applicant: WEST AFFUM HOLDINGS DAC

Inventor： Laura Marie Gustavson ,  Kerstin Dorst ,  Angela M. Stewart ,  Pamela F. Breske ,  Amanda K. Hall ,  Garrett McCann Kotlarchik ,  Dallas Eugene Meeker ,  Daniel James Finney ,  Eduard Johann Deml ,  Robert Reuben Buchanan ,  David Peter Finch ,  Phillip Dewey Foshee, Jr. ,  Douglas Keith Medema ,  Kenneth F. Cowan

IPC: A61N1/04 ,  A41C3/00 ,  A41D1/00 ,  A61N1/39

CPC classification number: A61N1/0484 ,  A41C3/0064 ,  A41D1/005 ,  A61N1/046 ,  A61N1/3904 ,  A61N1/3968 ,  A41D2300/32 ,  A41D2300/324 ,  A41D2300/326

Abstract: A supportive clothing article for a wearable cardioverter defibrillator (WCD), including a belt, the belt including a first end with a first portion of a fastener and a second end with a second portion of the fastener, wherein the belt is structured to fasten around the torso of patient below the chest area of the patient, the belt including a first conductive mesh portion adjacent the first end of the belt or the second end of the belt, two straps, a back portion extending from the belt at an intermediary position on the belt to each of the two straps, the back portion including a conductive mesh, a first support receptacle attached to and extending from the belt and attachable to one of the two straps, and a second support receptacle attached to and extending from the belt and attachable to the other of the two straps.

公开(公告)号：US12115364B2

公开(公告)日：2024-10-15

申请号：US17157639

申请日：2021-01-25

Applicant: G & H Technologies, LLC

Inventor： Gilbert Fregoso ,  Brad B. Heckerman

IPC: A61C17/02 ,  A61B18/04 ,  A61C1/06 ,  A61C1/07 ,  A61C3/00 ,  A61C3/03 ,  A61C5/40 ,  A61C5/50 ,  A61C17/16 ,  A61C17/20 ,  A61C19/06 ,  A61L2/025 ,  A61L2/10 ,  A61L2/14 ,  A61L2/18 ,  A61N1/04 ,  A61N1/05 ,  A61N1/30 ,  A61N1/32 ,  A61N1/44 ,  A61N5/06 ,  A61L2/00 ,  A61L2/22

CPC classification number: A61N1/0448 ,  A61B18/042 ,  A61C1/06 ,  A61C1/07 ,  A61C3/00 ,  A61C3/03 ,  A61C5/40 ,  A61C5/50 ,  A61C17/0202 ,  A61C17/16 ,  A61C17/20 ,  A61C19/063 ,  A61L2/025 ,  A61L2/10 ,  A61L2/14 ,  A61L2/18 ,  A61N1/04 ,  A61N1/0548 ,  A61N1/306 ,  A61N1/325 ,  A61N1/44 ,  A61N5/0603 ,  A61B2217/007 ,  A61L2/00 ,  A61L2/0088 ,  A61L2/22 ,  A61L2202/25 ,  A61N2005/0606 ,  A61N2005/0661 ,  F04C2270/0421

Abstract: An electrical discharge irrigation device includes a power source to produce power of a first voltage, a circuit coupled to the power source to convert the power of the first voltage to power of a second voltage where the second voltage is higher than the first voltage, a trigger to activate the circuit, an igniter coupled to the circuit to produce a spike, an electrical charge storage component coupled to the igniter the electrical charge storage component becoming conductive and storing an electrical charge after receiving the spike, and an output tip. The output tip includes an electrode and insulating material as an outer layer.

公开(公告)号：US20240335657A1

公开(公告)日：2024-10-10

申请号：US18731925

申请日：2024-06-03

Applicant: Washington University ,  Northwestern University

Inventor： Wilson Z. Ray ,  Matthew R. MacEwan ,  Zohny S. Zohny ,  John A. Rogers

IPC: A61N1/20 ,  A61N1/04 ,  A61N1/05 ,  A61N1/372 ,  A61N1/375

CPC classification number: A61N1/205 ,  A61N1/0456 ,  A61N1/0504 ,  A61N1/37217 ,  A61N1/375 ,  A61N1/20

Abstract: A system for stimulating tissue generally comprises a resorbable implant. The resorbable implant includes a substrate, at least one contact, and a transceiver, wherein the substrate, the at least one contact, and the transceiver are resorbable. The system also includes a controller configured to communicate with the transceiver of the resorbable implant and a power supply connected to the controller. The controller delivers power to the resorbable implant from the power supply. The resorbable implant delivers electrical stimulation to tissue when the resorbable implant receives power.