公开(公告)号：US20070275419A1

公开(公告)日：2007-11-29

申请号：US10527257

申请日：2002-09-09

Applicant: Jun Wu ,  Ying Luo

Inventor： Jun Wu ,  Ying Luo

IPC: G01N33/574 ,  C07H21/04 ,  C12P21/06 ,  C07K14/82 ,  C07K16/30

CPC classification number: C07K14/47

Abstract: The invention provides a new tumor tag, RL5 protein, the polynucleotide encoding RL5 protein, and the method of producing RL5 protein by recombinant technology. The invention also discloses the use of RL5 protein and the polynucleotides encoding RL5 protein, e.g., in diagnosing and treating tumor, as well as the pharmaceutical composition containing RL5 protein or the antibody against it.

Abstract translation: 本发明提供新的肿瘤标签RL5蛋白，编码RL5蛋白的多核苷酸，以及通过重组技术产生RL5蛋白的方法。 本发明还公开了使用RL5蛋白和编码RL5蛋白的多核苷酸，例如诊断和治疗肿瘤，以及含有RL5蛋白或抗体的抗体的药物组合物。

公开(公告)号：US20070238134A9

公开(公告)日：2007-10-11

申请号：US10220375

申请日：2001-03-02

Applicant: Ying Luo ,  Xiang Xu

Inventor： Ying Luo ,  Xiang Xu

IPC: G01N33/53 ,  G01N33/567 ,  C07H21/04 ,  C12N9/16 ,  C12P21/02 ,  C12N5/06

CPC classification number: C07K14/4738 ,  C12N9/16 ,  C12Y301/03016 ,  G01N33/5011 ,  G01N33/6872 ,  G01N2333/4739 ,  G01N2333/8114

Abstract: The present invention is directed to novel polypeptides, nucleic acids and related molecules which have an effect on or are related to the cell cycle. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided by the present invention are methods for identifying novel compositions which mediate cell cycle bioactivity, and the use of such compositions in diagnosis and treatment of disease.

Abstract translation: 本发明涉及对细胞周期有影响或与细胞周期有关的新型多肽，核酸和相关分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。 本发明还提供了鉴定介导细胞周期生物活性的新型组合物的方法，以及这些组合物在疾病诊断和治疗中的应用。

公开(公告)号：US07265214B2

公开(公告)日：2007-09-04

申请号：US10029115

申请日：2001-10-19

Applicant: Ying Luo ,  Simon Yu ,  Xiang Xu ,  Cindy Leo

Inventor： Ying Luo ,  Simon Yu ,  Xiang Xu ,  Cindy Leo

IPC: C07H21/04 ,  C12Q1/68 ,  C12N5/02

CPC classification number: C12N9/1205 ,  C12Q1/485 ,  G01N33/5041 ,  G01N2500/02

Abstract: The present invention provides compositions and methods for modulating cell proliferation, survival, morphology, and migration. Nucleic acids encoding proteins and proteins so encoded which are capable of modulating proliferation, survival, morphology and migration in mammalian cells are provided. Compositions and methods for the treatment of disorders related to cell proliferation, survival, morphology and migration are also provided. Prophylactics and methods for the prevention of such disorders are also provided. Also provided are compositions and methods for diagnostic and prognostic determination of such disorders. Further provided are assays for the identification of bioactive agents capable of modulating proliferation, survival, morphology and migration in mammalian cells.

Abstract translation: 本发明提供调节细胞增殖，存活，形态和迁移的组合物和方法。 提供了编码能够调节哺乳动物细胞中增殖，存活，形态和迁移的蛋白质和蛋白质的核酸。 还提供了用于治疗与细胞增殖，存活，形态和迁移相关的病症的组合物和方法。 还提供了预防和预防这种疾病的方法。 还提供了用于诊断和预测这些疾病的组合物和方法。 还提供了用于鉴定能够调节哺乳动物细胞中增殖，存活，形态和迁移的生物活性剂的测定。

公开(公告)号：US20070202645A1

公开(公告)日：2007-08-30

申请号：US11680121

申请日：2007-02-28

Applicant: Tien Ying Luo ,  Lakshmanna Vishnubhotla ,  Tushar P. Merchant ,  Rajesh A. Rao ,  Ramachandran Muralidhar

Inventor： Tien Ying Luo ,  Lakshmanna Vishnubhotla ,  Tushar P. Merchant ,  Rajesh A. Rao ,  Ramachandran Muralidhar

IPC: H01L21/8242

CPC classification number: H01L29/7885 ,  B82Y10/00 ,  H01L21/02164 ,  H01L21/02271 ,  H01L21/02304 ,  H01L21/02337 ,  H01L21/31612 ,  H01L29/40117 ,  H01L29/42332 ,  H01L29/7883

Abstract: An oxide layer formed by deposition is subject to a treatment process to repair bond defects of the oxide layer. In one embodiment, the layer is treated with nitric oxide. In one embodiment, a nitric oxide gas is flowed over the dielectric layer at an elevated temperature. In still another embodiment, the oxide layer is treated with fluorine. A layer is deposited over the oxide layer and a species containing fluorine is ion implanted into the layer. The wafer is heated where the species is driven to the oxide layer.

Abstract translation: 通过沉积形成的氧化物层经受处理工艺以修复氧化物层的结合缺陷。 在一个实施方案中，该层用一氧化氮处理。 在一个实施方案中，一氧化氮气体在升高的温度下流过电介质层。 在另一个实施方案中，用氟处理氧化物层。 在氧化物层上沉积一层，并且将含氟物质离子注入到该层中。 加热晶片，将物质驱动到氧化物层。

公开(公告)号：US06884685B2

公开(公告)日：2005-04-26

申请号：US10366777

申请日：2003-02-14

Applicant: Tien Ying Luo ,  Ricardo Garcia ,  Hsing H. Tseng

Inventor： Tien Ying Luo ,  Ricardo Garcia ,  Hsing H. Tseng

IPC: C23C16/30 ,  C23C16/40 ,  H01L21/28 ,  H01L21/314 ,  H01L21/316 ,  H01L29/51 ,  H01L21/336

CPC classification number: H01L21/28185 ,  C23C16/308 ,  C23C16/40 ,  H01L21/02181 ,  H01L21/02271 ,  H01L21/02362 ,  H01L21/28194 ,  H01L21/28202 ,  H01L21/3141 ,  H01L21/3143 ,  H01L21/31604 ,  H01L21/3162 ,  H01L21/31645 ,  H01L29/517 ,  H01L29/518

Abstract: A metal oxide high-k dielectric is deposited on a semiconductor wafer in a manner that reduces dangling bonds in the dielectric without significantly thickening interfacial oxide thickness. A metal oxide precursor and radical oxygen and/or radical nitrogen are co-flowed over the semiconductor wafer to form the high-k dielectric. The radicals bond to dangling bonds of the metal of the metal oxide during the deposition process that is performed at the regular deposition temperature of less than about 400 degrees Celsius. The radical oxygen and radical nitrogen do not require the higher temperatures generally required in an anneal in order to attach to the dangling bonds of the metal. Thus, a high temperature post deposition anneal, which tends to cause interfacial oxide growth, is not required. The dielectric is of higher quality than is typical because the dangling bonds are removed during deposition rather than after the dielectric has been deposited.

Abstract translation: 金属氧化物高k电介质沉积在半导体晶片上，以减少电介质中的悬挂键而不显着增加界面氧化物厚度。 金属氧化物前体和自由基氧和/或自由基氮共同流过半导体晶片以形成高k电介质。 在沉积过程中，基团键合到金属氧化物的金属的悬挂键，其在小于约400摄氏度的常规沉积温度下进行。 自由基氧和自由基氮不需要在退火中通常需要的较高温度以附着到金属的悬挂键上。 因此，不需要倾向于引起界面氧化物生长的高温后沉积退火。 电介质的质量比典型值高，因为在沉积期间移除悬挂键，而不是沉积电介质后。

公开(公告)号：US09307936B2

公开(公告)日：2016-04-12

申请号：US13467728

申请日：2012-05-09

Applicant: Rebecca K. Gottlieb ,  Ying Luo ,  Ning Yang ,  James Geoffrey Chase

Inventor： Rebecca K. Gottlieb ,  Ying Luo ,  Ning Yang ,  James Geoffrey Chase

IPC: A61B5/00 ,  A61B5/145 ,  A61B5/1495 ,  A61B5/1486

CPC classification number: A61B5/14532 ,  A61B5/14865 ,  A61B5/1495 ,  A61B5/4839 ,  A61B5/6849 ,  A61B5/7239 ,  A61B5/7275 ,  A61B5/743 ,  G06F19/00

Abstract: Disclosed are methods, apparatuses, etc. for providing a visual expression of the performance of one or more blood glucose sensors. In one particular example, a relative comparison of a rate of change sensor blood glucose and a rate of change in reference blood glucose may be expressed in a polar plot or graph. The polar plot or graph may then be generated onto a visual medium.

Abstract translation: 公开了用于提供一个或多个血糖传感器的性能的视觉表达的方法，装置等。 在一个具体实例中，变化率血糖值与参考血糖变化率的相对比较可以用极坐标图或曲线图表示。 然后可以将极坐标图或图形生成到视觉介质上。

公开(公告)号：US20140303163A1

公开(公告)日：2014-10-09

申请号：US14007130

申请日：2011-03-24

Applicant: Ying Luo

Inventor： Ying Luo

IPC: C07D471/04 ,  C07D403/04

CPC classification number: C07D471/04 ,  A61K31/506 ,  C07D403/04

Abstract: The present invention discloses use of compounds of formula (I) in preventing and treating inflammatory disorder.

Abstract translation: 本发明公开了式（I）化合物在预防和治疗炎症性疾病中的应用。

公开(公告)号：US20120283538A1

公开(公告)日：2012-11-08

申请号：US13102390

申请日：2011-05-06

Applicant: Jefferson Rose ,  Ashwin K. Rao ,  Ning Yang ,  Chia-Hung Chiu ,  Ying Luo ,  Rebecca K. Gottlieb

Inventor： Jefferson Rose ,  Ashwin K. Rao ,  Ning Yang ,  Chia-Hung Chiu ,  Ying Luo ,  Rebecca K. Gottlieb

IPC: A61B5/1468

CPC classification number: A61B5/14735 ,  A61B5/14532 ,  G01N27/3272

Abstract: Embodiments of the invention provide analyte sensors and sensor systems such as amperometric glucose sensors used in the management of diabetes as well as optimized methods for monitoring analytes using such sensors and sensor systems.

Abstract translation: 本发明的实施方案提供分析物传感器和传感器系统，例如用于糖尿病管理的电流葡萄糖传感器以及使用这种传感器和传感器系统监测分析物的优化方法。

公开(公告)号：US20110273551A1

公开(公告)日：2011-11-10

申请号：US13138190

申请日：2009-01-21

Applicant: Ruiduo Yang ,  Ying Luo ,  Tao Zhang

Inventor： Ruiduo Yang ,  Ying Luo ,  Tao Zhang

IPC: G06K9/00 ,  H04N5/225

CPC classification number: G06F3/017 ,  G06K9/00355 ,  G06K9/3233

Abstract: The invention relates to a robust method to control interactive media using gestures. A method of controlling a multimedia device, using face detection and (hot spot) motion, providing robust accuracy in issued commands, wherein the method involves the following steps: extracting a hot spot area using a current captured image (Ci), calculate and analyze the difference between the current captured image (Ci) and a previous captured image (Ci−1), resulting in Di, applying an erosion on the Di to remove small areas, applying extracted (hot spot) motion areas as masks to filter out non-hot spot area motion, add Di to build a motion image, find the largest x, y and the smallest x, y coordinates of all the detected motion connected components, denote each as Ix, Iy, sx and sy, and perform an algorithm to determine if a hand gesture represents a command to control a multimedia device.

Abstract translation: 本发明涉及使用手势控制交互式媒体的鲁棒方法。 一种使用面部检测和（热点）运动来控制多媒体设备的方法，在发出的命令中提供鲁棒的准确性，其中该方法包括以下步骤：使用当前拍摄图像（Ci）提取热点区域，计算和分析 当前拍摄图像（Ci）与先前拍摄图像（Ci-1）之间的差异，导致Di，在Di上施加侵蚀以去除小区域，应用提取的（热点）运动区域作为掩模， - 点光区运动，添加Di构建运动图像，找到所有检测到的运动连接分量的最大x，y和最小x，y坐标，表示为Ix，Iy，sx和sy，并执行算法 以确定手势是否表示控制多媒体设备的命令。

公开(公告)号：US08054534B2

公开(公告)日：2011-11-08

申请号：US12650425

申请日：2009-12-30

Applicant: Ying Luo ,  Kuan-Hong Hsieh ,  Chun-Wei Pan

Inventor： Ying Luo ,  Kuan-Hong Hsieh ,  Chun-Wei Pan

IPC: G02B26/00 ,  G09G3/34

CPC classification number: G02F1/167 ,  G02F2001/1672

Abstract: An electrophoretic paper device is provided. The electrophoretic paper device includes a plurality of pixel electrodes arranged on a lower substrate. The electrophoretic paper device also includes an upper substrate having a common electrode that covers an entire area corresponding to a display surface. The electrophoretic paper device further includes an electrophoretic ink layer, which includes a plurality of tubular cavities and each of the tubular cavities contains suspension fluid and a plurality of charged pigment particles dispersed in the suspension fluid.

Abstract translation: 提供电泳纸装置。 电泳纸装置包括布置在下基板上的多个像素电极。 电泳纸装置还包括具有覆盖对应于显示表面的整个区域的公共电极的上基板。 电泳纸装置还包括电泳油墨层，其包括多个管状空腔，并且每个管状空腔包含分散在悬浮液中的悬浮液和多个带电颜料颗粒。