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    MICROTOME SECTIONABLE BIOPSY SUPPORT FOR ORIENTING TISSUE SAMPLES
    62.
    发明申请
    MICROTOME SECTIONABLE BIOPSY SUPPORT FOR ORIENTING TISSUE SAMPLES 有权
    用于面向组织样品的MICROTOME部分生物支持

    公开(公告)号：US20100184127A1

    公开(公告)日：2010-07-22

    申请号：US12692208

    申请日：2010-01-22

    申请人： Warren P. Williamson, IV ,  Stephen P. Whitlatch ,  Carlos A. Saez

    发明人： Warren P. Williamson, IV ,  Stephen P. Whitlatch ,  Carlos A. Saez

    IPC分类号： G01N1/28 ,  C12M1/00

    CPC分类号： B01L9/52 ,  G01N1/06 ,  G01N1/312 ,  G01N1/36 ,  G01N33/4833 ,  Y10T436/25

    摘要： Tissue orientation devices include a perforated tissue support with at least one perforated channel for receiving a tissue sample, and a plurality of tabs configured to extend along and into the channel to retain the tissue sample during processing and embedding. Tissue orientation devices include elongated legs coupled together for holding one or more biopsy tissue samples therebetween. Associated methods include using the cassettes and orientation devices to hold and orient tissue samples for processing, embedding and microtome sectioning.

    摘要翻译： 组织取向装置包括具有至少一个用于接收组织样本的穿孔通道的穿孔组织支撑件，以及多个突出部，其被构造成沿着和延伸通道以在加工和嵌入期间保持组织样本。 组织取向装置包括连接在一起的细长腿以在其间保持一个或多个活检组织样本。 相关方法包括使用盒和取向装置来保持和定向组织样品进行加工，嵌入和切片机切片。

    DEVICE TO PERMIT OFFPUMP BEATING HEART CORONARY BYPASS SURGERY
    66.
    发明申请
    DEVICE TO PERMIT OFFPUMP BEATING HEART CORONARY BYPASS SURGERY 有权

    公开(公告)号：US20090099411A1

    公开(公告)日：2009-04-16

    申请号：US12331722

    申请日：2008-12-10

    申请人： Paul A. Spence ,  Warren P. Williamson, IV ,  Mark Ortiz

    发明人： Paul A. Spence ,  Warren P. Williamson, IV ,  Mark Ortiz

    IPC分类号： A61B17/00

    CPC分类号： A61B17/0218 ,  A61B17/00491 ,  A61B17/02 ,  A61B17/0206 ,  A61B17/0293 ,  A61B17/04 ,  A61B17/064 ,  A61B17/068 ,  A61B17/29 ,  A61B2017/00305 ,  A61B2017/00309 ,  A61B2017/0243 ,  A61B2017/308

    摘要： A suction cup adapted to engage a surface of a beating heart with sufficient force to move the beating heart to an unnatural position upon moving the suction cup, while the suction cup maintains engagement with the surface of the heart and the heart continues to beat. Various suction cups are described each including at least a first chamber having a flexible rim and configured to engage the surface of the beating heart and a second chamber smaller than the first chamber and fluidly connected therewith. A suspension device configured to engage a beating heart and maintain engagement via suction while moving the suspension device to move the beating heart to an unnatural position and maintain the beating heart in the unnatural position to perform a surgical procedure, while the heart continues to beat, includes a suction cup and a support arm connected thereto. The suction cup has a first chamber configured to engage the surface of the beating heart and a second chamber smaller than the first chamber and fluidly connected therewith. The second chamber is adapted to fluidly connect the first chamber with a source of suction. The support arm is movable with the suction cup to effect movement of the beating heart after engagement of the suction cup to a surface of the beating heart. A method of manipulating a beating heart to orient the beating heart in a desired position for performing a surgical procedure includes providing a suction cup having a first chamber configured to engage the surface of the beating heart, and a second chamber smaller than the first chamber and fluidly connected with the first chamber, the second chamber being further fluidly connected to a source of suction; contacting a surface of the beating heart with the first chamber; applying suction between the first chamber and the surface of the beating heart, thereby engaging the suction member with the surface of the beating heart; and moving the suction member while maintaining engagement with the surface of the beating heart, thereby moving the beating heart.

    Method and apparatus for performing anastomosis with eversion of tissue edges and joining of exposed intima of the everted tissue
    68.
    发明授权
    Method and apparatus for performing anastomosis with eversion of tissue edges and joining of exposed intima of the everted tissue 失效
    用于通过外翻组织边缘进行吻合的方法和装置，以及接合外露组织的暴露内膜

    公开(公告)号：US07497865B2

    公开(公告)日：2009-03-03

    申请号：US10855604

    申请日：2004-05-26

    申请人： Geoffrey H. Willis ,  Thomas A. Kramer ,  Paul A. Spence ,  George T. Christakis ,  Timothy J. McCoy ,  John W. Davis ,  Bradley D. Blackwood ,  Peter Callas ,  Michael Francis Wei ,  Jonathan L. Podmore ,  Andrew Knight ,  Thomas J. Ward ,  Warren P. Williamson, IV

    发明人： Geoffrey H. Willis ,  Thomas A. Kramer ,  Paul A. Spence ,  George T. Christakis ,  Timothy J. McCoy ,  John W. Davis ,  Bradley D. Blackwood ,  Peter Callas ,  Michael Francis Wei ,  Jonathan L. Podmore ,  Andrew Knight ,  Thomas J. Ward ,  Warren P. Williamson, IV

    IPC分类号： A61B17/08 ,  A61B17/10 ,  A61B17/04

    CPC分类号： A61B17/1152 ,  A61B17/11 ,  A61B17/115 ,  A61B2017/1107 ,  A61B2017/1132 ,  A61B2017/1135 ,  A61B2017/1139

    摘要： A ring for use in anastomosis. Preferably, the ring is integrally formed from metal, and includes a ring portion and tines and docking members that extend from the ring portion. The ring portion and tines are malleable, and preferably also the docking members are malleable. The ring portion and tines are malleable in the sense that once deformed from a first shape into a second shape, they will not relax back into the first shape from the second. To install the ring in a vessel with the ring portion extending around an incision or other orifice, the tines pierce the tissue around the orifice and are curled against an anvil. The action of curling the tines inverts the tissue near the orifice edges to expose the inside surface of the vessel or organ. Other aspects of the invention are a method and apparatus for installing an anastomosis ring in an incision or other orifice in a vessel or other organ, a method and apparatus for precisely aligning two anastomosis rings (each installed in an incision or other orifice of a different organ) and fastening the aligned rings together. The clips can be crimped onto the aligned rings, or they can be spring clips which are sprung onto the aligned rings to clamp the rings together by spring force. Also within the scope of the invention are crimping and spring clips for use in listening together two aligned anastomosis rings. In other embodiments, the invention is a method for performing an anastomosis by installing an anastomosis ring in an orifice in an organ, installing another anastomosis ring in an orifice in another organ, precisely aligning the two installed anastomosis rings, and fastening the aligned rings together.

    摘要翻译： 用于吻合的戒指。 优选地，环由金属一体地形成，并且包括从环部延伸的环部分和尖齿和对接构件。 环形部分和尖齿是可延展的，并且优选的是对接部件是可延展的。 环形部分和尖齿在从第一形状变形成第二形状的意义上是可延展的，它们将不会从第二形状放松回第一形状。 为了将环安装在具有围绕切口或其他孔口延伸的环部分的容器中，齿刺穿孔周围的组织并且卷绕在砧座上。 卷曲尖齿的作用使孔边缘附近的组织反转以暴露血管或器官的内表面。 本发明的其它方面是用于将吻合环安装在容器或其他器官中的切口或其它孔中的方法和装置，用于精确地对准两个吻合环（每个安装在切口或不同的其他孔中的其他孔中的方法和装置） 器官）并将对准的环固定在一起。 夹子可以压接在对准的环上，或者它们可以是弹簧夹，弹簧夹被弹簧上对准的环，以通过弹簧力将环夹在一起。 也在本发明的范围内的是压接和弹簧夹，用于一起收听两个对准的吻合环。 在其他实施例中，本发明是一种通过在器官中的孔中安装吻合环来进行吻合的方法，在另一个器官的孔中安装另一个吻合环，精确对准两个安装的吻合环，并将对准的环固定在一起 。

    Device to permit offpump beating heart coronary bypass surgery
    69.
    发明授权
    Device to permit offpump beating heart coronary bypass surgery 有权
    允许偏心跳动心脏冠状动脉旁路手术的装置

    公开(公告)号：US07195591B2

    公开(公告)日：2007-03-27

    申请号：US11063478

    申请日：2005-02-23

    申请人： Paul A. Spence ,  Warren P. Williamson, IV

    发明人： Paul A. Spence ,  Warren P. Williamson, IV

    IPC分类号： A61B17/00

    CPC分类号： A61B17/02 ,  A61B17/0206 ,  A61B17/0218 ,  A61B2017/0243 ,  A61B2017/306 ,  A61B2017/308

    摘要： A heart retractor links lifting of the heart and regional immobilization which stops one part of the heart from moving to allow expeditious suturing while permitting other parts of the heart to continue to function whereby coronary surgery can be performed on a beating heart while maintaining cardiac output unabated and uninterrupted. Circumflex coronary artery surgery can be performed using the heart retractor of the present invention. The retractor includes a plurality of flexible arms and a plurality of rigid arms as well as a surgery target immobilizing element. One form of the retractor can be used in minimally invasive surgery, while other forms of the retractor can accommodate variations in heart size and paracardial spacing.

    摘要翻译： 心脏牵开器连接心脏的抬起和区域性固定，其阻止心脏的一部分移动以允许快速缝合，同时允许心脏的其他部分继续发挥作用，从而可以在跳动的心脏上进行冠状动脉手术，同时保持心输出量不减 并不间断。 可以使用本发明的心脏牵开器进行环形冠状动脉手术。 牵开器包括多个柔性臂和多个刚性臂以及手术目标固定元件。 牵开器的一种形式可用于微创手术，而其他形式的牵开器可以适应心脏尺寸和心包间隔的变化。

    Apparatus and method for harvesting and handling tissue samples for biopsy analysis
    70.
    发明授权
    Apparatus and method for harvesting and handling tissue samples for biopsy analysis 有权
    收集和处理组织样本用于活检分析的装置和方法

    公开(公告)号：US07156814B1

    公开(公告)日：2007-01-02

    申请号：US09890177

    申请日：1998-10-05

    申请人： Warren P. Williamson, IV ,  Stephen Whitlach ,  Dominic DiNovo ,  Douglas Allen ,  Thomas Ward

    发明人： Warren P. Williamson, IV ,  Stephen Whitlach ,  Dominic DiNovo ,  Douglas Allen ,  Thomas Ward

    IPC分类号： A61B10/00 ,  G01N1/30 ,  G01N33/48 ,  C12M1/12 ,  C12M1/22 ,  C12M3/00

    CPC分类号： G01N1/36 ,  A61B10/0096 ,  G01N1/06 ,  G01N1/312 ,  G01N2001/315

    摘要： A sectional cassette (10) for use in a process for harvesting and handling tissue samples for biopsy analysis is disclosed. In the procedure, a tissue biopsy sample is placed on a tissue trapping supporting material (A′) that can withstand tissue preparation procedures, and which can be cut with a microtome. The tissue is immobilized on the material, and the material and the tissue are held in the cassette (10) subjected to a process for replacing tissue fluids with wax. The tissue and supporting material are sliced for mounting on slides using a microtome. Harvesting devices and containers (200) using the filter material (202) are disclosed. An automated process is also disclosed.

    摘要翻译： 公开了一种用于采集和处理组织样本用于活组织检查分析的方法的分段盒（10）。 在该过程中，将组织活检样品放置在可以承受组织制备程序的组织捕获支撑材料（A'）上，并且可以用切片机切割。 将组织固定在材料上，并将材料和组织保持在经过用蜡代替组织液的过程的盒（10）中。 使用切片机将组织和支撑材料切片以安装在载玻片上。 公开了使用过滤材料（202）的收获装置和容器（200）。 还公开了一种自动化过程。