利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

102 条记录 (耗时 0.034 秒)

    Ethylene-propylene coatings for sutures
    61.
    发明授权
    Ethylene-propylene coatings for sutures 有权
    用于缝线的乙烯 - 丙烯涂层

    公开(公告)号：US6083243A

    公开(公告)日：2000-07-04

    申请号：US145319

    申请日：1998-09-01

    申请人： Henry Pokropinski ,  Alastair W. Hunter ,  Karl W. Brennan ,  Dennis D. Jamiolkowski

    发明人： Henry Pokropinski ,  Alastair W. Hunter ,  Karl W. Brennan ,  Dennis D. Jamiolkowski

    IPC分类号： A61B17/00 ,  A61B17/06 ,  A61L17/00 ,  A61L17/14 ,  D06M15/227 ,  D06M23/10 ,  A61B17/04

    CPC分类号： D06M23/10 ,  A61B17/06166 ,  A61L17/145 ,  D06M15/227 ,  D06M7/00 ,  A61B2017/00831 ,  D06M2200/40

    摘要： A suture having a coating thereon of an ethylene-propylene copolymer, and a method of coating a suture which comprises the steps of coating the surface of the suture with an effective amount of a solution of ethylene-propylene copolymer in an organic solvent, and then removing the solvent from the coated suture. The copolymer preferably has an average molecular weight of from about 25,000 to about 500,000 g/mole, and a mole percentage of about 55 to 70 percent ethylene and about 30 to 45 percent propylene. The coating provides an alternative to silicone, which has previously been used as a coating for sutures, and exhibits excellent performance properties, such as tactile smoothness, pliability, and knot tiedown performance.

    摘要翻译： 一种在其上具有乙烯 - 丙烯共聚物的涂层的缝合线，以及一种涂覆缝合线的方法，其包括以下步骤：用有效量的乙烯 - 丙烯共聚物溶液在有机溶剂中涂覆缝合线的表面，然后 从涂层缝合线中除去溶剂。 共聚物的平均分子量优选为约25,000至约500,000g / mol，摩尔百分数为约55至70％的乙烯和约30至45％的丙烯。 该涂层提供了先前已经用作缝线涂层的硅树脂的替代物，并且表现出优异的性能特性，例如触感平滑度，柔韧性和结结合性能。

    Radiation-curable, urethane-acrylate prepolymers and crosslinked polymers
    64.
    发明授权
    Radiation-curable, urethane-acrylate prepolymers and crosslinked polymers 失效
    可辐射固化，氨基甲酸酯 - 丙烯酸酯预聚物和交联聚合物

    公开(公告)号：US5674921A

    公开(公告)日：1997-10-07

    申请号：US382325

    申请日：1995-02-01

    申请人： Donald W. Regula ,  Michael F. Bregen ,  Stuart L. Cooper ,  Dennis D. Jamiolkowski ,  Rao S. Bezwada

    发明人： Donald W. Regula ,  Michael F. Bregen ,  Stuart L. Cooper ,  Dennis D. Jamiolkowski ,  Rao S. Bezwada

    IPC分类号： A61L31/06 ,  A61L31/14 ,  C08F290/14 ,  C08G18/67 ,  A61B17/08 ,  B29C35/02 ,  C08L75/16 ,  G03C5/00

    CPC分类号： A61L31/06 ,  A61L31/148 ,  C08F290/147 ,  C08G18/672 ,  C08G2230/00

    摘要： A radiation-curable prepolymer of a polyurethane endtipped with an hydroxy (acrylate or methacrylate) is disclosed. The polyurethane is derived from the reaction of a polyfunctional isocyanate with a hydrolyzable oligomer of an anhydrous cyclic ester of an hydroxy acid. Crosslinked polymers prepared by irradiating the prepolymers are also disclosed. The crosslinked polymers are bioabsorbable and biocompatible with bodily tissue, yet still maintain the outstanding mechanical properties one would expect from a polyurethane. The prepolymers and crosslinked polymers are especially well-suited for the fabrication of surgical devices, particularly wound closure devices such as surgical staples and clips, in a stereolithography apparatus.

    摘要翻译： 公开了一种端接有羟基（丙烯酸酯或甲基丙烯酸酯）的聚氨酯的可辐射固化预聚物。 聚氨酯衍生自多官能异氰酸酯与羟基酸的无水环状酯的可水解低聚物的反应。 还公开了通过照射预聚物制备的交联聚合物。 交联聚合物是生物可吸收的并且与身体组织生物相容，但仍然保持着从聚氨酯所期望的突出的机械性能。 预聚物和交联聚合物特别适用于在立体光刻设备中制造手术装置，特别是诸如外科缝钉和夹子的伤口闭合装置。

    RIGID REINFORCING EXOSKELETAL SLEEVE FOR DELIVERY OF FLOWABLE BIOCOMPATIBLE MATERIALS
    67.
    发明申请
    RIGID REINFORCING EXOSKELETAL SLEEVE FOR DELIVERY OF FLOWABLE BIOCOMPATIBLE MATERIALS 审中-公开
    用于输送可流动的生物成分材料的刚性增强弹性套管

    公开(公告)号：US20140031788A1

    公开(公告)日：2014-01-30

    申请号：US13556790

    申请日：2012-07-24

    申请人： An-Min Jason Sung ,  Dennis D. Jamiolkowski ,  Guanghui Zhang

    发明人： An-Min Jason Sung ,  Dennis D. Jamiolkowski ,  Guanghui Zhang

    IPC分类号： A61M25/02 ,  A61B17/34

    CPC分类号： A61M5/1414 ,  A61B17/00491 ,  A61B17/34 ,  A61B17/3415 ,  A61B2017/00331 ,  A61B2017/00469 ,  A61B2017/3405 ,  A61B2017/347 ,  A61M5/1424 ,  A61M25/02 ,  A61M2005/1416

    摘要： Exoskeletal devices or sleeves that can be used with the delivery tube of an applicator device to help dispense fluids, typically flowable biocompatible materials such as hemostatic agents, adhesives, or sealants, onto specific sites in the human body for a medical reason are disclosed.The exoskeletal devices or sleeves are rigid, pre-shaped, and snappably or slidably affixed to the delivery tube. The exoskeletal devices or sleeves do not come into contact with the flowable biocompatible fluid being dispensed, and they can be placed at any position along the delivery tube to address different application situations. Once the exoskeletal device or sleeve is in place, it can optionally be locked onto the delivery tube to prevent further sliding under stresses when pushed against tissue. Multiple exoskeletal devices or sleeves can also be used to achieve more complicated shapes for hard-to-reach anatomical sites.

    摘要翻译： 公开了可以与敷贴器装置的输送管一起使用的外骨骼装置或套筒，以帮助将液体（通常是可流动的生物相容性材料，例如止血剂，粘合剂或密封剂）分配到人体的特定部位，用于医学原因。 外骨骼装置或套筒是刚性的，预成形的，并且可滑动地或可滑动地固定到输送管。 外骨骼装置或套管不会与正在分配的可流动的生物相容性流体接触，并且它们可以放置在沿输送管的任何位置以解决不同的应用情况。 一旦外骨骼装置或套筒就位，它可以可选地被锁定在输送管上，以防止在压在组织上时在应力下的进一步滑动。 还可以使用多个外骨骼装置或袖子来实现难以到达的解剖部位的更复杂的形状。

    High glass transition temperature absorbable microspheres
    68.
    发明授权
    High glass transition temperature absorbable microspheres 有权
    高玻璃化转变温度可吸收微球

    公开(公告)号：US08580307B2

    公开(公告)日：2013-11-12

    申请号：US11472830

    申请日：2006-06-22

    申请人： Dennis D. Jamiolkowski ,  Modesto Erneta ,  Robert DiLuccio

    发明人： Dennis D. Jamiolkowski ,  Modesto Erneta ,  Robert DiLuccio

    IPC分类号： A61K9/14

    CPC分类号： A61K8/025 ,  A61K8/85 ,  A61K9/1647 ,  A61K2800/412 ,  A61L27/18 ,  A61L27/50 ,  A61L27/58 ,  Y10T428/2982 ,  C08L67/04

    摘要： Absorbable microspheres comprising a copolymer formed from greater than 80 to about 99 mole percent D,L-lactide, L(−)-lactide, D(+)-lactide, or meso-lactide and combinations thereof, and about 1 to less than 20 mole percent of a different second monomer selected from the group consisting of p-dioxanone and trimethylene carbonate and combinations thereof, said microspheres having a particle size ranging from about 5 to 2000 microns. Also described herein are formulations comprising such absorbable microspheres.

    摘要翻译： 可吸收的微球包含由大于80-约99摩尔％的D，L-丙交酯，L（ - ） - 丙交酯，D（+） - 丙交酯或内消旋丙交酯及其组合形成的共聚物和约1至小于20 摩尔百分比的选自对二恶烷酮和三亚甲基碳酸酯及其组合的不同的第二单体，所述微球具有约5至2000微米的粒度。 本文还描述了包含这种可吸收微球体的制剂。