Abstract:
A method for modifying the refractive index of an optical, polymeric material. The method comprises irradiating select regions of the optical, polymeric material with a focused, visible or near-IR laser having a pulse energy from 0.05 nJ to 1000 nJ. The irradiation results in the formation of refractive optical structures, characterized by a change in refractive index, exhibit little or no scattering loss, and exhibit no significant differences in the Raman spectrum with respect to the non-irradiated optical, polymeric material. The method can be used to modify the refractive index of an intraocular lens following the surgical implantation of the intraocular lens in a human eye. The invention is also directed to an optical device comprising refractive optical structures, wherein the refractive structures are characterized by a change in refractive index, exhibit little or no scattering loss, and exhibit no significant differences in the Raman spectrum with respect to the non-irradiated optical, polymeric material.
Abstract:
A method of introducing ions into an ion trap and an ion storage apparatus are described. Introduction means are used to introduce first ions into an ion trap through an entrance aperture to the ion trap. An operating condition of the introduction means is adjusted to cause second ions, of different polarity to the first ions to be introduced into the ion trap through the same entrance aperture.
Abstract:
An interactive user interface (UI) to manage searching of data is disclosed. The UI includes a first display panel configured to display a parent context view and a child context view thereon and a second display panel configured to display a diagram of an enlarged portion of the child context view.
Abstract:
A mass spectrometer has a pulsed ion source, a first ion trap (10) for trapping ions generated by the pulsed ion source and for locating trapped ions for subsequent ejection from the first ion trap. A pulse of cooling gas is introduced into the first ion trap (10) at a peak pressure suitable for enabling the first ion trap (10) to trap ions. A turbomolecular pump (17) reduces the pressure of cooling gas before the trapped ions are ejected from the first ion trap (1) towards a second ion trap (20) for analysis. The pulsed ion source has a sample plate (14) which forms an end wall of the first ion trap (10).
Abstract:
A model for a circuit cell used in timing and signal integrity analysis in an integrated circuit design is automatically generated. A behavioral model, such as a gate current model is used in which the current in the circuit cell is determined as a function of the input voltage and the output voltage of the circuit cell as well as the history of at least one of the current, voltage, and charge values of the circuit cell. For example, the current in the circuit cell may be a function of the history of the current, which may be calculated incrementally using recursive convolution at each time step when using the model.
Abstract:
A source container for use in a computer system executing problem determination tools in an integrated environment across a computer network, the source container comprising a list of pathways to a plurality of source files and module objects. A software development may create the source container independently or within the front end of a problem determination tool. The front end of the problem determination tools sends the source container to its engine, and only source files and module objects having a pathway in the source container are analyzed within the engine of the problem determination tool. Furthermore, the results of the analysis of only those source files and module objects having a pathway in the source container are returned to the front end of the problem determination tool for viewing by the software developer. The front ends of the tools of the integrated development environment, the source files, the module objects, the engines of the tools, and different tools may all be located on different servers and/or clients across a computer network.
Abstract:
The invention provides human kinases and phosphatases (KAP) and polnucleotides which identify and encode KAP. The invention also provides expresson vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of KAP.
Abstract:
This invention relates to the determination of RNA quality, or RNA integrity, in a biological sample. The extent of RNA degradation, or retention of RNA integrity, is determined based upon the comparison of the relative amount of two sequences of a representative RNA molecule in the sample. Compositions and methods related to the determination are provided to assess RNA quality.
Abstract:
The invention provides human proteases (PRTS) and polynucleotides which identify and encode PRTS. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PRTS.
Abstract:
The invention provides human protein modification and maintenance molecules (PMMM) and polynucleotides which identify and encode PMMM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PMMM.