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95 条记录 (耗时 0.026 秒)

    Apparatus for performing heat-exchanging, chemical reactions
    62.
    发明授权
    Apparatus for performing heat-exchanging, chemical reactions 有权
    反应容器

    公开(公告)号：US06660228B1

    公开(公告)日：2003-12-09

    申请号：US09468690

    申请日：1999-12-21

    申请人： Ronald Chang ,  Douglas B. Dority ,  Lee A. Christel ,  Robert Yuan ,  Kurt E. Petersen

    发明人： Ronald Chang ,  Douglas B. Dority ,  Lee A. Christel ,  Robert Yuan ,  Kurt E. Petersen

    IPC分类号： B01L300

    CPC分类号： B01L7/52 ,  B01J19/0093 ,  B01J2219/00788 ,  B01J2219/00873 ,  B01J2219/00963 ,  B01J2219/0097 ,  B01L3/508 ,  B01L9/00 ,  B01L2300/042 ,  B01L2300/0858 ,  B01L2300/1827 ,  F28D2021/0077 ,  F28F13/00 ,  G01N21/0332 ,  G01N35/0099 ,  G01N2035/00376 ,  G01N2035/0405 ,  Y10T436/2575

    摘要： The present invention provides an apparatus for performing heat-exchanging chemical reactions, such as nucleic acid amplification. The apparatus includes a reaction vessel having a chamber for holding a sample for chemical reaction and optical detection. The vessel has a rigid frame defining the side walls of the chamber, and flexible sheets attached to opposite sides of the frame to form opposing major walls of the chamber. The frame further includes a port and a channel connecting the port to the chamber. The temperature of the sample is controlled by opposing plates positioned to receive the chamber of the vessel between them. The apparatus also includes a plunger which is inserted into the channel of the vessel to seal the port and increase pressure in the chamber. The increased pressure forces the flexible major walls of the chamber to contact and conform to the surfaces of the plates, thus ensuring optimal thermal conductance between the plates and the chamber. The apparatus also includes thermal elements for heating or cooling the plates, as well as optics for detecting analytes in the sample.

    摘要翻译： 本发明提供了一种用于进行诸如核酸扩增的热交换化学反应的装置。 该装置包括具有用于保持用于化学反应和光学检测的样品的室的反应容器。 容器具有限定室的侧壁的刚性框架，以及附接到框架的相对侧的柔性片以形成腔室的相对的主壁。 框架还包括端口和将端口连接到室的通道。 样品的温度通过相对的板来控制，所述相对的板定位成在它们之间容纳容器的腔室。 该装置还包括插入容器的通道以密封端口并增加腔室中的压力的​​柱塞。 增加的压力迫使室的柔性主壁与板的表面接触并且符合板的表面，从而确保板和室之间的最佳热传导。 该装置还包括用于加热或冷却板的热元件以及用于检测样品中分析物的光学元件。

    Valve and valved container for use with a syringe fitting
    63.
    发明授权
    Valve and valved container for use with a syringe fitting 失效
    用于注射器配件的阀门和阀门容器

    公开(公告)号：US5569235A

    公开(公告)日：1996-10-29

    申请号：US263790

    申请日：1994-06-21

    申请人： James B. Ross ,  Ronald Chang

    发明人： James B. Ross ,  Ronald Chang

    IPC分类号： A61M39/26 ,  A61M5/00 ,  A61M19/00 ,  F16K51/00

    CPC分类号： A61M39/26

    摘要： A valve for a needleless syringe fitting is disclosed. The valve has a receptacle fitting for releasable attachment to the syringe fitting, a valve chamber, a valve seat adjacent the chamber, and elastomeric sealing bowl within the chamber. The bowl is deformed and partially inverted when the syringe fitting is attached to the receptacle fitting, causing the valve to open. Also disclosed is a valved container in which a vial is sealed by a valve of this type.

    摘要翻译： 公开了一种无针注射器配件的阀。 阀具有用于可释放地附接到注射器配件，阀室，邻近腔室的阀座和腔室内的弹性体密封碗的插座配件。 当注射器配件连接到插座配件时，碗变形并部分倒置，导致阀打开。 还公开了一种带阀的容器，其中小瓶由这种类型的阀密封。

    Track and hold circuit with an input transistor held on during hold mode
    64.
    发明授权
    Track and hold circuit with an input transistor held on during hold mode 失效
    在保持模式期间，保持输入晶体管的保持电路

    公开(公告)号：US5457418A

    公开(公告)日：1995-10-10

    申请号：US349240

    申请日：1994-12-05

    申请人： Ronald Chang

    发明人： Ronald Chang

    IPC分类号： G11C27/02 ,  H03K17/0416 ,  H03K17/04 ,  H03K5/00

    CPC分类号： H03K17/04166 ,  G11C27/026

    摘要： A track and hold circuit is disclosed which may be used in high speed analog to digital conversions. The circuit includes a control transistor which keeps the circuit's input transistor in a conductive state even when the circuit is in hold mode. As a result, the track and hold circuit achieves a high switching speed while minimizing input voltage spikes.

    摘要翻译： 公开了可用于高速模数转换的轨道和保持电路。 该电路包括控制晶体管，即使当电路处于保持模式时，该控制晶体管仍将电路的输入晶体管保持在导通状态。 结果，跟踪和保持电路实现了高切换速度，同时最小化了输入电压尖峰。

    Differential amplifier
    66.
    发明授权
    Differential amplifier 有权
    差分放大器

    公开(公告)号：US08604877B2

    公开(公告)日：2013-12-10

    申请号：US13331558

    申请日：2011-12-20

    申请人： Charles Chang ,  Ronald Chang

    发明人： Charles Chang ,  Ronald Chang

    IPC分类号： H03F3/45

    CPC分类号： H03F3/45197 ,  H03F3/45475 ,  H03F3/45946 ,  H03F2203/45082 ,  H03F2203/45352 ,  H03F2203/45702

    摘要： A differential amplifier is provided in the present invention. The differential amplifier includes an amplifying module having a resistive ratio, receiving an input voltage, and amplifying the input voltage as an output voltage in accordance with the resistive ratio; and a feedback module coupled with the amplifying module and generating a feedback signal in accordance with the input voltage and the output voltage for regulating the output voltage.

    摘要翻译： 在本发明中提供了一种差分放大器。 差分放大器包括具有电阻比的放大模块，接收输入电压，并根据电阻比将输入电压放大为输出电压; 以及与放大模块耦合的反馈模块，并根据输入电压和输出电压产生反馈信号以调节输出电压。

    Method and apparatus for storing and dispensing reagent beads
    68.
    发明授权
    Method and apparatus for storing and dispensing reagent beads 有权
    用于存储和分配试剂珠的方法和装置

    公开(公告)号：US08409531B2

    公开(公告)日：2013-04-02

    申请号：US12512926

    申请日：2009-07-30

    申请人： Ronald Chang ,  Douglas B. Dority ,  Steve Montgomery

    发明人： Ronald Chang ,  Douglas B. Dority ,  Steve Montgomery

    IPC分类号： B01L3/00 ,  G01N31/00 ,  G01N33/543 ,  B65G47/14 ,  B23Q7/04 ,  B65H3/06 ,  B65H3/24 ,  B65H3/44 ,  B65H1/08 ,  B65H3/00 ,  G01N1/00 ,  G07F9/00 ,  G07F11/16 ,  B65G59/00

    CPC分类号： B01L3/527 ,  B01J19/0046 ,  B01J2219/00468 ,  B01J2219/005 ,  B01J2219/00657 ,  B01L3/0289 ,  B01L2200/0647 ,  B01L2200/16 ,  G01N2035/00574 ,  Y10T436/25

    摘要： Embodiments of the invention provide an efficient and effective technique for storing and dispensing reagent beads. In some embodiments, an apparatus is provided for dispensing reagent beads contained in a bead storage device which includes a bead carrier having a plurality of wells; a plurality of reagent beads disposed in the wells; and a cover tape releasably attached to the bead carrier to cover the wells and retain the reagent beads in the wells. The apparatus comprises a channel in which to place the bead storage device with the bead carrier facing a support wall of the channel and the cover tape facing a stripping wall of the channel. The stripping wall includes a stripping gap disposed between a stripping edge and an opposite edge, and a dispense opening provided adjacent the opposite edge on a side of the stripping wall opposite from the stripping edge. The cover tape is insertable through the stripping gap to be pulled against the stripping edge to peel the cover tape from the bead carrier to move the wells of the bead carrier inside the channel toward the dispense opening and expose the wells individually to dispense the reagent beads.

    摘要翻译： 本发明的实施方案提供了用于存储和分配试剂珠的有效和有效的技术。 在一些实施例中，提供了一种用于分配包含在珠子存储装置中的试剂珠粒的装置，其包括具有多个孔的珠粒载体; 设置在所述孔中的多个试剂珠; 以及可剥离地附接到胎圈载体以覆盖孔并将试剂珠保持在孔中的覆盖带。 该装置包括一个通道，在该通道中，珠子存放装置使胎圈承载件面向通道的支撑壁，盖带面向通道的剥离壁。 剥离壁包括设置在剥离边缘和相对边缘之间的剥离间隙，以及在剥离壁的与剥离边缘相对的一侧上邻近相对边缘设置的分配开口。 覆盖带可以通过剥离间隙被插入以被拉靠在剥离边缘上，以从胎圈载体上剥离覆盖带，以将通道内的胎圈载体的孔移动到分配开口，并单独暴露孔以分配试剂珠 。

    DRIVING CIRCUIT FOR LED
    69.
    发明申请
    DRIVING CIRCUIT FOR LED 审中-公开
    LED驱动电路

    公开(公告)号：US20120217890A1

    公开(公告)日：2012-08-30

    申请号：US13370474

    申请日：2012-02-10

    申请人： Charles Chang ,  Ronald Chang

    发明人： Charles Chang ,  Ronald Chang

    IPC分类号： H05B37/02

    CPC分类号： H05B33/0815

    摘要： A driving circuit for driving a load is provided. The driving circuit includes a control module providing a control signal to adjust a load current flowing through the load; and a voltage clamping module providing a power voltage to the control module.

    摘要翻译： 提供用于驱动负载的驱动电路。 驱动电路包括控制模块，其提供控制信号以调节流过负载的负载电流; 以及向控制模块提供电源电压的电压钳位模块。