公开(公告)号：US20130003044A1

公开(公告)日：2013-01-03

申请号：US13541171

申请日：2012-07-03

Applicant: John Maier ,  Jeffrey Cohen ,  Ryan Priore

Inventor： John Maier ,  Jeffrey Cohen ,  Ryan Priore

IPC: G01J3/28 ,  G01J3/44

CPC classification number: G01N21/84 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/0224 ,  G01J3/0248 ,  G01J3/027 ,  G01J3/0291 ,  G01J3/10 ,  G01J3/1256 ,  G01J3/26 ,  G01J3/2823 ,  G01J3/44 ,  G01J3/4406 ,  G01J5/0846 ,  G01J2005/0077 ,  G01N21/35 ,  G01N21/3581 ,  G01N21/359 ,  G01N21/65 ,  G01N21/658 ,  G01N2201/129 ,  G02B21/0092 ,  G02B21/14 ,  G02B21/16

Abstract: The present disclosure provides for a system and method for assessing chronic exposure of a biological sample, such as a bodily fluid, to an analyte of interest. A biological sample may be illuminated to thereby generate a one or more pluralities of interacted photons. These interacted photons may be detected to thereby generate one or more spectroscopic data sets representative of a biological sample. Spectroscopic data sets generated may be compared to at least one reference data set. Each reference data set may be associated with a known exposure to a known analyte. The present disclosure contemplates that the system and method disclosed herein may be used to analyze exposure of biological samples to at least one analyte over time. Data sets may be obtained at various time intervals to assess changes in a molecular composition as a result of chronic exposure to an analyte.

Abstract translation: 本公开提供了用于评估生物样品（例如体液）到感兴趣分析物的慢性暴露的系统和方法。 可以照射生物样品，从而产生一个或多个相互作用的光子。 可以检测这些相互作用的光子，从而生成代表生物样品的一个或多个光谱数据集。 可以将生成的光谱数据集与至少一个参考数据集进行比较。 每个参考数据集可以与已知分析物的已知暴露相关联。 本公开内容考虑到本文公开的系统和方法可用于分析生物样品随时间的至少一种分析物的暴露。 可以以不同的时间间隔获得数据集，以评估作为慢性暴露于分析物的结果的分子组成的变化。

公开(公告)号：US08344334B2

公开(公告)日：2013-01-01

申请号：US12681863

申请日：2008-09-22

Applicant: Raymond Douglas Coker ,  John Tetteh ,  Michael Paul Andreou

Inventor： Raymond Douglas Coker ,  John Tetteh ,  Michael Paul Andreou

IPC: G01N21/64

CPC classification number: G01N21/65 ,  G01N21/64 ,  G01N21/658 ,  G01N33/02 ,  G01N2021/651 ,  G01N2021/656 ,  G01N2201/129

Abstract: A method for the detection or determination of a target comprising a plurality of target compounds, or derivatised target compounds, said method comprising: immobilizing said target on a carrier, directing radiation at said target, said radiation being selected to cause said target to emit a relevant radiation, detecting said relevant radiation emitted by said target, and analyzing said detected radiation to identify and/or quantify the plurality of target compounds in said target.

Abstract translation: 一种用于检测或测定包含多种目标化合物或衍生化的靶化合物的靶的方法，所述方法包括：将所述靶固定在载体上，引导所述靶上的辐射，选择所述辐射使所述靶发射 相关辐射，检测由所述目标发射的相关辐射，并分析所述检测到的辐射以识别和/或定量所述靶中的多个目标化合物。

公开(公告)号：US20120228199A1

公开(公告)日：2012-09-13

申请号：US13481028

申请日：2012-05-25

Applicant: Steven H. Modiano ,  Kevin L. Deppermann ,  James Crain ,  Sam R. Eathington ,  Mike Graham

Inventor： Steven H. Modiano ,  Kevin L. Deppermann ,  James Crain ,  Sam R. Eathington ,  Mike Graham

IPC: B07C5/00 ,  G01J3/46 ,  G01B11/24 ,  G01N21/55

CPC classification number: G06K9/00 ,  B07C5/00 ,  B07C5/10 ,  B07C5/34 ,  B07C5/3422 ,  B07C5/3425 ,  G01J3/0218 ,  G01J3/10 ,  G01N21/253 ,  G01N21/6428 ,  G01N21/6452 ,  G01N21/6456 ,  G01N21/85 ,  G01N2021/0339 ,  G01N2021/8592 ,  G01N2201/0627 ,  G01N2201/129

Abstract: Systems and methods are provided for evaluating and sorting seeds based on characteristics of the seeds. One system includes an imaging and analysis subsystem that collects image data from the seeds and analyzes the collected image data for characteristics of the seeds. This subsystem can include an imaging theater having minors that reflect image data from the seeds to an imaging device for collection. The system can also include an off-loading and sorting subsystem configured to sort the seeds based on their characteristics. And, one method includes illuminating the seeds and collecting image data from the seeds for determining their characteristics. The image data can be collected from at least three portions of the seeds at each of a plurality of sequentially changing spectral wavelengths. In addition (or alternatively), the image data can be collected from top and bottom portions of the seeds using a single imaging device.

Abstract translation: 提供的系统和方法用于根据种子的特征来评估和分选种子。 一个系统包括成像和分析子系统，其从种子收集图像数据，并分析所收集的图像数据以获得种子的特征。 该子系统可以包括具有将来自种子的图像数据反映到用于收集的成像装置的未成年人的成像影院。 该系统还可以包括卸载和排序子系统，其被配置为基于其特征对种子进行分类。 并且，一种方法包括照亮种子并从种子收集图像数据以确定其特性。 可以从多个顺序变化的光谱波长中的每一个的种子的至少三个部分收集图像数据。 另外（或替代地），可以使用单个成像装置从种子的顶部和底部收集图像数据。

公开(公告)号：US08194245B2

公开(公告)日：2012-06-05

申请号：US12907597

申请日：2010-10-19

Applicant: Gerard Hotier ,  Philibert Leflaive ,  Mathieu Digne ,  Philippe Marteau ,  Jean-Lucien Molle ,  Michel Leclercq ,  Sophie Dewally-Morel

Inventor： Gerard Hotier ,  Philibert Leflaive ,  Mathieu Digne ,  Philippe Marteau ,  Jean-Lucien Molle ,  Michel Leclercq ,  Sophie Dewally-Morel

IPC: G01J3/44

CPC classification number: G01N21/65 ,  B01D15/1821 ,  G01N21/8507 ,  G01N2201/084 ,  G01N2201/1211 ,  G01N2201/129

Abstract: The present invention describes a method for measuring the concentrations of species present at one point of a separation unit functioning in simulated moving bed mode (SMB), using an immersing probe located at one point in the unit or on one of the streams entering or leaving said unit, and a thermocouple located in the vicinity of the immersing probe, in which a Raman spectrum obtained using a laser source functioning at a wavelength of 785 nm is utilized.

Abstract translation: 本发明描述了一种用于测量存在于模拟移动床模式（SMB）中运行的分离单元的一个点处的物种的浓度的方法，其使用位于该单元中的一个点处的浸入探针或者进入或离开的一个流 所述单元和位于浸渍探头附近的热电偶，其中使用使用波长为785nm的激光源获得的拉曼光谱。

公开(公告)号：US20120123681A1

公开(公告)日：2012-05-17

申请号：US13139969

申请日：2009-10-14

Applicant: Debora Marcondes Bastos Pereira Milori ,  Ladislau Martin Neto ,  Ednaldo Jose Ferreira ,  Ana Flavia Zaghi ,  Andre Leonardo Venancio

Inventor： Debora Marcondes Bastos Pereira Milori ,  Ladislau Martin Neto ,  Ednaldo Jose Ferreira ,  Ana Flavia Zaghi ,  Andre Leonardo Venancio

IPC: G06F19/00 ,  G01N21/64 ,  G01N21/25

CPC classification number: G01N21/6486 ,  G01N33/0098 ,  G01N2021/6421 ,  G01N2201/129

Abstract: The present invention relates to a method, apparatus and a system of fast diagnosis of stresses and diseases in higher plants. The proposed methodology is based on the hypothesis of that when a plant is in imbalance; there are changes in its metabolism that render an alteration of the chemical composition of its organs. This chemical alteration leads to a change in the physical properties, such as the fluorescence of the leaves. Due to the complexity of the material of the leaves, the present method proposes that the signal be treated with statistical methods and that the classification is made through softwares based on machine learning. As an example of the application of the invention, the results are shown for the Greening disease in citrus. Currently, Greening is the most severe citrus disease since there is no treatment available for it and due to its high dissemination rate and the fact that it affects all varieties of orange trees, being the diagnosis performed through visual inspection, which renders high subjectivity, high error percentage and the disease is only diagnosed after the expression of the symptoms (˜8 months). During the asymptomatic phase, the infected tree is a source of dissemination of the disease. The present invention can perform the asymptomatic diagnosis of Greening disease from the leaf with a percentage of correct diagnosis higher than 80%.

Abstract translation: 本发明涉及高等植物中应力和疾病快速诊断的方法，装置和系统。 所提出的方法是基于当植物不平衡时的假设; 其代谢改变会改变其器官的化学成分。 这种化学变化导致物理性质的改变，例如叶子的荧光。 由于叶片材料的复杂性，本方法建议采用统计方法对信号进行处理，并通过基于机器学习的软件进行分类。 作为本发明的应用的实例，结果显示了柑橘中的绿化病。 目前，绿化是最严重的柑橘病，因为没有可用的治疗方法，由于其传播率高，影响所有品种的橙树，是通过目视检查进行的诊断，其主观性高，高 错误百分比，疾病仅在症状表达后诊断（〜8个月）。 在无症状期间，感染的树是疾病的传播来源。 本发明可以从正确诊断率高于80％的叶中进行绿色疾病的无症状诊断。

公开(公告)号：US08159656B2

公开(公告)日：2012-04-17

申请号：US12443849

申请日：2007-10-04

Applicant: Yoshimasa Miura ,  Masayuki Shirao ,  Takashi Ohmori ,  Takuya Saiwaki

Inventor： Yoshimasa Miura ,  Masayuki Shirao ,  Takashi Ohmori ,  Takuya Saiwaki

IPC: G01J3/00

CPC classification number: G01N21/33 ,  G01N2201/129

Abstract: A first step of measuring a change over time in the spectral transmission spectrum of a measurement sample by its exposure to the light of a light source including an ultraviolet radiation for a preset light exposure time, a second step of performing a correction according to the change over time in the spectral transmission spectrum of the measurement sample based on the result of the measurement obtained by the first step, and a third step of calculating the final in vitro predicted SPF of the measurement sample using the result of the correction obtained by the second step are included.

Abstract translation: 第一步骤，通过对包含紫外线的光源的光的曝光来测量测量样本的光谱透射光谱随时间的变化，以达到预设的曝光时间;第二步骤，根据变化执行校正 基于由第一步骤获得的测量结果在测量样本的光谱透射光谱中随时间推移的第三步骤，以及使用由第二步获得的校正结果计算测量样品的最终体外预测SPF的第三步骤 包括步骤。

公开(公告)号：US08158175B2

公开(公告)日：2012-04-17

申请号：US12545574

申请日：2009-08-21

Applicant: Wilfred Marcellien Bourg, Jr.

Inventor： Wilfred Marcellien Bourg, Jr.

IPC: A23L1/01

CPC classification number: G01N33/02 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/78 ,  G01N21/94 ,  G01N33/10 ,  G01N33/14 ,  G01N2021/3595 ,  G01N2201/129

Abstract: Disclosed is a method for the real time measurement of acrylamide in a food product. Wavelength emission data is collected from a food product. The same food product is tested off-line in an analytical laboratory for levels of acrylamide pre-cursors or acrylamide. The wavelength emission data is then correlated with the off-line laboratory data.

Abstract translation: 公开了一种用于实时测量食品中丙烯酰胺的方法。 从食品中收集波长发射数据。 相同的食品在分析实验室中离线测试丙烯酰胺前体或丙烯酰胺的水平。 然后将波长发射数据与离线实验室数据相关联。

公开(公告)号：US20120078473A1

公开(公告)日：2012-03-29

申请号：US13314703

申请日：2011-12-08

Applicant: Trent Ridder ,  Bentley Laaksonen ,  Ben Ver Steeg

Inventor： Trent Ridder ,  Bentley Laaksonen ,  Ben Ver Steeg

IPC: B60K28/06

CPC classification number: A61B5/0071 ,  A61B5/117 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/4845 ,  G01J3/02 ,  G01J3/0218 ,  G01J3/0229 ,  G01J3/0291 ,  G01J3/14 ,  G01J3/189 ,  G01N21/274 ,  G01N21/359 ,  G01N21/474 ,  G01N2201/129

Abstract: The present invention discloses apparatuses and methods for non-invasive determination of attributes of human tissue by quantitative infrared spectroscopy. The embodiments of the present invention include subsystems optimized to contend with the complexities of the tissue measurements. The subsystems can include an illumination/modulation subsystem, a tissue sampling subsystem, a calibration maintenance subsystem, a data acquisition subsystem, and a computing subsystem. Embodiments of the present invention provide analyte property determination and identity determination or verification from the same spectroscopic information, making unauthorized use or misleading results less likely that in systems that include separate analyte and identity determinations. The invention can be used to prevent operation of automobiles or other equipment unless the operator has an acceptable alcohol concentration, and to limit operation of automobiles or other equipment to authorized individuals who are not intoxicated or drug-impaired.

Abstract translation: 本发明公开了通过定量红外光谱法非侵入性地确定人体组织属性的装置和方法。 本发明的实施例包括被优化以应对组织测量的复杂性的子系统。 子系统可以包括照明/调制子系统，组织采样子系统，校准维护子系统，数据采集子系统和计算子系统。 本发明的实施方案提供了来自相同光谱信息的分析物质性质确定和鉴别确认或验证，使得在包括单独的分析物和身份确定的系统中不太可能使用未经授权的使用或误导结果。 本发明可以用于防止汽车或其他设备的操作，除非操作人员具有可接受的酒精浓度，并且将汽车或其他设备的操作限制于不会中毒或药物受损的授权个人。

公开(公告)号：US20110257492A1

公开(公告)日：2011-10-20

申请号：US13141559

申请日：2010-01-29

Applicant: Tanja Maria Greve ,  Kristine Birklund Andersen

Inventor： Tanja Maria Greve ,  Kristine Birklund Andersen

IPC: A61B6/00

CPC classification number: A61B5/441 ,  A61B5/0059 ,  A61B5/0075 ,  A61B5/445 ,  G01N21/3563 ,  G01N21/359 ,  G01N2201/129 ,  G01N2800/104 ,  G01N2800/20 ,  G01N2800/202 ,  G01N2800/205

Abstract: The invention relates to a non-invasive method for determining the state of a skin disorder using Near Infrared (NIR) spectroscopy as well as a system and an apparatus therefor.

Abstract translation: 本发明涉及使用近红外（NIR）光谱法确定皮肤病症状态的非侵入性方法，以及一种系统及其装置。

公开(公告)号：US07847947B2

公开(公告)日：2010-12-07

申请号：US11917019

申请日：2006-06-27

Applicant: Colin Jeffress

Inventor： Colin Jeffress

IPC: G01N21/00 ,  G01N21/55

CPC classification number: G01J3/02 ,  G01J3/0291 ,  G01N21/55 ,  G01N21/8507 ,  G01N33/025 ,  G01N2201/129

Abstract: A lance assembly (10) for spectroscopically sampling bulk product (8) is disclosed. The assembly comprises: an elongate lance body (11) having a longitudinal axis (15), a proximal end (12) for maneuvering and a head (19) defining a cavity (18). Housed within the cavity (18) is a spectroscopic receiver (20) having a field of view and a radiant energy source (40) providing a beam of energy to be reflected from the bulk product (8) to the receiver 20 through a window (30). The window (30) has an external surface (31) which, in use, is in contact with the bulk product (8). The beam of energy and the field of view of the receiver (20) are both directed towards the external surface (31) so as to allow sampling adjacent the external surface (31).

Abstract translation: 公开了一种用于光谱取样散装产品（8）的喷枪组件（10）。 组件包括：具有纵向轴线（15），用于操纵的近端（12）和限定空腔（18）的头部（19）的细长喷枪体（11）。 设置在空腔（18）内的是具有视野的分光学接收器（20）和辐射能源（40），其通过窗口（40）提供能够从散装产品（8）反射到接收器20的能量束 30）。 窗口（30）具有在使用中与散装产品（8）接触的外表面（31）。 能量束和接收器（20）的视野均指向外表面（31），以允许邻近外表面（31）进行取样。