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    METHODS AND SYSTEMS FOR GENOME ANALYSIS
    61.
    发明申请
    METHODS AND SYSTEMS FOR GENOME ANALYSIS 审中-公开
    基因分析方法与系统

    公开(公告)号：US20160092631A1

    公开(公告)日：2016-03-31

    申请号：US14877877

    申请日：2015-10-07

    申请人： Omicia, Inc. ,  University of Utah

    发明人： Mark YANDELL ,  Marc SINGLETON ,  Martin REESE ,  Karen EILBECK

    IPC分类号： G06F19/24 ,  G06F19/26 ,  G06F19/22

    CPC分类号： G16B20/00 ,  G06F7/02 ,  G06F17/241 ,  G16B30/00 ,  G16B40/00 ,  G16B45/00 ,  G16B50/00

    摘要： The present disclosure provides methods and systems for prioritizing phenotype-causing genomic variants. The methods include using variant prioritization analyses and in combination with biomedical ontologies using a sophisticated re-ranking methodology to re-rank these variants based on phenotype information. The methods can be useful in any genomics study and diagnostics; for example, rare and common disease gene discovery, tumor growth mutation detection, drug responder studies, metabolic studies, personalized medicine, agricultural analysis, and centennial analysis.

    摘要翻译： 本公开提供了用于将表型造成的基因组变体优先化的方法和系统。 这些方法包括使用变体优先级分析，并结合生物医学本体使用复杂的重新排序方法，根据表型信息重新排列这些变体。 该方法可用于任何基因组学研究和诊断; 例如，罕见和常见的疾病基因发现，肿瘤生长突变检测，药物应答者研究，代谢研究，个性化医学，农业分析和百年分析。

    Determining hemodynamic performance
    62.
    发明授权
    Determining hemodynamic performance 有权
    确定血液动力学性能

    公开(公告)号：US09173575B2

    公开(公告)日：2015-11-03

    申请号：US13378353

    申请日：2010-06-17

    申请人： Stephen Woodford

    发明人： Stephen Woodford

    IPC分类号： G01N33/48 ,  G01N31/00 ,  G01N33/50 ,  A61B5/0205 ,  G06F19/00 ,  G06F19/26 ,  G06F19/12 ,  G06F17/10 ,  A61B5/00 ,  A61B5/02 ,  A61B5/029 ,  A61B5/021 ,  A61B5/024

    CPC分类号： A61B5/0205 ,  A61B5/02028 ,  A61B5/021 ,  A61B5/024 ,  A61B5/029 ,  A61B5/412 ,  A61B5/743 ,  G06F17/10 ,  G06F19/00 ,  G06F19/12 ,  G06F19/26 ,  G06F19/32 ,  G16H50/20 ,  G16H50/30 ,  G16H50/50 ,  G16H50/70

    摘要： A method for determining haemodynamic performance in a human or animal subject comprises receiving at a processor data representing haemodynamic variables measured from the subject over time. The haemodynamic variables comprise at least two of Systemic Perfusion Pressure (SPP), Systemic Vascular Resistance (SVR), Cardiac Output (CO), Heart Rate (HR) and Stroke Volume (SV). The data are processed to produce a display signal for causing a display device to present a visual mapping relating the haemodynamic variables according to the relationship SPP=CO×SVR and the visual mapping is displayed on a display device. The visual mapping may be corrected Heart Rate (HR) or include a second mapping which facilitates an adjustment to take account of HR.

    摘要翻译： 用于确定人或动物受试者的血液动力学性能的方法包括在处理器处接收表示从受试者随时间测量的血液动力学变量的数据。 血液动力学变量包括系统灌注压（SPP），全身血管阻力（SVR），心输出量（CO），心率（HR）和中风量（SV）中至少两项。 处理数据以产生显示信号，以使显示装置根据关系SPP = CO×SVR呈现与血液动力学变量相关的视觉映射，并且可视映射显示在显示装置上。 视觉映射可以被校正心率（HR）或包括有助于考虑HR的调整的第二映射。

    System, method and apparatus for classifying digital data
    64.
    发明授权
    System, method and apparatus for classifying digital data 有权
    用于分类数字数据的系统，方法和装置

    公开(公告)号：US09143393B1

    公开(公告)日：2015-09-22

    申请号：US13351780

    申请日：2012-01-17

    申请人： Robert Bird ,  Greg Barton ,  Matthew Whitlock

    发明人： Robert Bird ,  Greg Barton ,  Matthew Whitlock

    IPC分类号： G06F15/16 ,  H04L12/24 ,  G06K9/62 ,  G06N3/04 ,  G06K9/46 ,  G06K9/00 ,  G06F19/28 ,  G06F19/26 ,  G06F19/12

    CPC分类号： H04L41/046 ,  G06F19/12 ,  G06F19/26 ,  G06F19/28 ,  G06K9/00442 ,  G06K9/46 ,  G06K9/6202 ,  G06K9/6248 ,  G06N3/0436 ,  H04L41/0631 ,  H04L41/0893

    摘要： A data classification system comprising a server adapted to receive data elements from a computer network, compute a distance between the elements and a plurality of representative elements such that where the distance is less than a threshold, the input elements are associated with the representative element and where the distance is not less than the threshold, the input element is stored as a new representative element. A method of classifying network traffic is further disclosed that can include providing a server adapted to receive data from a network, compute a distance between the data elements and representative data elements such that where the distance is less than a threshold, the input elements are associated with the representative element and where the distance is not less than the threshold, the input element is stored as a new representative element.

    摘要翻译： 一种数据分类系统，包括适于从计算机网络接收数据元素的服务器，计算元件与多个代表元件之间的距离，使得在距离小于阈值的情况下，输入元件与代表元件相关联， 其中距离不小于阈值，输入元素被存储为新的代表元素。 还公开了一种分类网络业务的方法，其可以包括提供适于从网络接收数据的服务器，计算数据元素和代表性数据元素之间的距离，使得在距离小于阈值的情况下，输入元素相关联 利用代表性元素并且距离不小于阈值，输入元素被存储为新的代表元素。

    SYSTEM FOR POLYNUCLEOTIDE CONSTRUCT DESIGN, VISUALIZATION AND TRANSACTIONS TO MANUFACTURE THE SAME
    67.
    发明申请
    SYSTEM FOR POLYNUCLEOTIDE CONSTRUCT DESIGN, VISUALIZATION AND TRANSACTIONS TO MANUFACTURE THE SAME 审中-公开
    多核结构系统设计，可视化和交易制造

    公开(公告)号：US20150120265A1

    公开(公告)日：2015-04-30

    申请号：US14241874

    申请日：2012-08-30

    申请人： Omri Amirav-Drory ,  Nir Ben Moshe

    发明人： Omri Amirav-Drory ,  Nir Ben Moshe

    IPC分类号： G06F19/20 ,  G06F17/50 ,  G06F19/12 ,  G06F19/26 ,  G06Q30/06

    CPC分类号： G16B25/00 ,  G06F17/50 ,  G06Q30/0629 ,  G06Q30/0635 ,  G16B5/00 ,  G16B30/00 ,  G16B45/00 ,  G16B50/00

    摘要： The present invention disclose a computerized system for designing nucleic acid sequences for gene expression comprising; (a) a server [103] for hosting a database [106] (b) a network connection [102] and (c) a computer readable medium [101] comprising functional modules including (i) a design module for enabling designing of nucleic acid constructs; (ii) interactive user interface module for visualizing biological information relating to design operations; (iii) transaction module for purchasing a user-designed or pre-stocked nucleic acid constructs (iv) a detecting module for detecting designed nucleic acid sequences comprises harmful sequences; the system is operating in a method of: (a) visualizing biological information; (b) designing nucleic acid sequences; (c) detecting and notifying when harmful sequences are designed; (d) providing means for transactions regarding ordering and purchasing said synthesized nucleic acids.

    摘要翻译： 本发明公开了一种用于设计用于基因表达的核酸序列的计算机化系统，包括： （a）用于托管数据库的服务器[106]（b）网络连接[102]和（c）包括功能模块的计算机可读介质，其包括（i）用于实现核酸设计的设计模块 酸性结构; （ii）用于可视化与设计操作相关的生物信息的交互式用户界面模块; （iii）用于购买用户设计或预存储的核酸构建体的交易模块（iv）用于检测设计的核酸序列的检测模块包括有害序列; 该系统的运行方式为：（a）可视化生物信息; （b）设计核酸序列; （c）设计有害序列时的检测和通知; （d）提供关于订购和购买所述合成核酸的交易的手段。

    REMINDER, CLASSIFICATION, AND PATTERN IDENTIFICATION SYSTEMS AND METHODS FOR HANDHELD DIABETES MANAGEMENT DEVICES
    68.
    发明申请
    REMINDER, CLASSIFICATION, AND PATTERN IDENTIFICATION SYSTEMS AND METHODS FOR HANDHELD DIABETES MANAGEMENT DEVICES 有权
    提示，分类和模式识别系统和手段糖尿病管理设备的方法

    公开(公告)号：US20150012223A1

    公开(公告)日：2015-01-08

    申请号：US13936534

    申请日：2013-07-08

    申请人： Roche Diagnostics Operations, Inc.

    发明人： Timothy N. Aykroyd ,  Amy C. Day ,  Paul J. Galley ,  Horst Merkle ,  Christen A. Rees ,  Michelle M. Stevens ,  Scott A. Wooldridge

    IPC分类号： G06F19/26

    CPC分类号： G06F19/26 ,  A61B5/14532 ,  A61B5/7275 ,  G06F19/00 ,  G06F19/3456 ,  G16H20/10 ,  G16H50/20

    摘要： A method includes: measuring a blood glucose (bG) level in a blood sample; storing the bG level and a time of receipt of the blood sample; storing a classification of the blood sample; in response to the receipt of the blood sample, selecting a group of stored bG levels having the classification of the blood sample and that were received within a predetermined period before receipt of the blood sample; calculating a bG evaluation parameter from the selected bG levels; evaluating the bG evaluation parameter in relation to first predetermined criteria, the first predetermined criteria including a first threshold indicative of a high bG level or a low bG level; selectively displaying an indication of recognition of a pattern in the selected bG levels when the bG evaluation parameter is greater than or less than the first threshold; and selectively removing the indication from the display.

    摘要翻译： 一种方法包括：测量血液样品中的血糖（bG）水平; 存储bG水平和接收血液样本的时间; 存储血液样本的分类; 响应于所述血液样本的接收，选择具有所述血液样本分类并在接收到所述血液样本之前的预定时间段内接收的一组存储的bG水平; 从所选择的bG级别计算bG评估参数; 评估与第一预定标准相关的bG评估参数，所述第一预定准则包括指示高bG级别或低bG级别的第一阈值; 当所述bG评估参数大于或小于所述第一阈值时，选择性地显示所选择的bG级别中的模式的识别指示; 并从显示器中选择性地去除指示。