摘要:
A method and system for creating a levelling surface for use in levelling a substantially uneven ground surface, optimised for a single plane, row cropping, or dryland cropping with no rows (a surface for row cropping will typically optimise the surface with a defined water flow direction and a surface for dryland cropping will typically optimise the surface to allow water flow in any direction). Terrain data is collected, at least one constraint corresponding to desired surface characteristics is inputted, and a data transformation engine is operated, wherein the data transformation engine optimises the terrain data for at least one terrain variable, generates an optimised terrain model that substantially complies with the at least one constraint, and outputs a levelling surface. The levelling surface may be outputted to a three-dimensional controller for land-levelling machinery which could then shift the soil from the existing terrain to match the levelling surface.
摘要:
Methods and systems for identifying biological marker-placebo effect correlations are provided. Clinical trial design and data analysis of clinical trial data is modified to accommodate marker-placebo effect correlations.
摘要:
Microfluidic devices for manipulating relatively dense materials, such as colloidal rod particles, are provided. Microfluidic devices for separating a denser first material from a less-dense second material are provided. Methods of manipulating a relatively dense first material, for example, colloidal rod particles, and separating the first material from a less-dense second material, are provided. Methods of marking samples or sample components with relatively dense materials, are also provided.
摘要:
The present invention relates to business methods for discovery of therapeutic and diagnostic products by identifying variations that occur in the human genome, relating these variations to one another, and, ultimately, relating these variations to the genetic bases of phenotype such as disease resistance, disease susceptibility or drug response.
摘要:
The invention provides a collection of polymorphic sites associated with variations in human skin color, and genes containing or proximal to the sites.
摘要:
Various embodiments described in the application relate to an apparatus, system, and method for generating, within a conduit, discrete volumes of one or more fluids that are immiscible with a second fluid. The discrete volumes can be used for biochemical or molecular biology procedures involving small volumes, for example, microliter-sized volumes, nanoliter-sized volumes, or smaller. The system can comprise an apparatus comprising at least one conduit operatively connected to one or more pumps for providing discrete volumes separated from one another by a fluid that is immiscible with the fluid(s) of the discrete volumes, for example, aqueous immiscible-fluid-discrete volumes separated by an oil.
摘要:
A fluid processing device, system, kit, and method, are provided, for processing a liquid sample. The device can comprise a substrate comprising one or more fluid processing pathways, wherein each pathway can comprise at least a first region, one or more outlet regions, and a channel connecting and in fluid communication with the respective first region and the respective one or more outlet regions, and a cover provided in communication with at least a portion of the top surface of the substrate. The cover can comprise one or more slits each slit respectively aligned with a different respective one of the one or more outlet regions. A removal seal can be applied to the cover to seal the one or more slits.
摘要:
Several methods are described for assessing an individual's likelihood of developing or exhibiting a multifactorial trait. The methods include determining a plurality of genotypes for the individual at a plurality of biallelic polymorphic loci, using the genotypes to compute a score for the individual, and comparing the score to at least one threshold value.
摘要:
An apparatus comprises a scanning electron microscope (SEM) (1) positioned over a manipulation chamber (2) which houses a sample holder (3). The walls of the manipulation chamber (2) support two probes (4, 4a) and the sample holder (3) is able to hold a sample (5), such as carbon nanotubes (10a) carried on a substrate (10). The apparatus can selectively move and apply voltages and currents to the probe or probes (4, 4a) and sample holder (3) under the SEM (1). By controlling the current that is passed across a contact between the probe (4) and a carbon nanotube (10a), a conditioned weld is formed. Likewise, by controlling the current that is passed along a carbon nanotube (10a), the nanotube (10a) can be annealed. Using both the probes (4, 4a) a carbon nanotube can be held and cut at any position along its length. This allows the formation of novel carbon nanotube structures.
摘要:
The present invention provides a lateral flow format and materials and methods for using the format in a variety of applications. More particularly, the present invention provides single-layer lateral flow formats, materials and methods for detecting the presence of an analyte using a test strip comprising a dry porous medium comprising a single hydrophilic matrix. Devices are also provided as well as methods of making and using the format. The format is particularly useful for diagnosis of physiological and genetic conditions. In addition, the present invention provides methods and materials for concentrating a reagent in a porous medium.