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公开(公告)号：US20160168601A1
公开(公告)日：2016-06-16
申请号：US15051710
申请日：2016-02-24
发明人： Takashi Mimitsuka , Kentaro Ishii , Ken Morita , Masashi Higasa , Kenji Sawai , Hideki Sawai , Katsushige Yamada , Shinichi Minegishi
IPC分类号： C12P7/56
CPC分类号： C12P7/56 , C12M29/18 , C12M47/10 , C12N9/00 , C12P1/00 , C12P7/02 , C12P7/40 , C12P13/001 , C12P13/04 , C12P13/08 , C12P19/34 , C12P21/02
摘要： A method of producing a chemical product includes cultivating microorganisms or culture cells in a fermentation tank; transferring a culture liquid from the fermentation tank to a membrane separation tank to filter the culture liquid through a separation membrane; and collecting a fermentation product from a filtration liquid as the chemical product while refluxing an unfiltered culture liquid that has not been filtered to be joined to the culture liquid on an upstream side of the membrane separation tank, wherein one portion of the culture liquid to be transferred from the fermentation tank is allowed to bypass the membrane separation tank depending on a pressure at a culture liquid flow-in side of the membrane separation tank.
摘要翻译： 生产化学产品的方法包括在发酵罐中培养微生物或培养细胞; 将培养液从发酵罐转移到膜分离罐中，通过分离膜过滤培养液; 并从作为化学产品的过滤液中收集发酵产物，同时在膜分离罐的上游侧回流未过滤的待过滤培养液与培养液接合的培养液，其中一部分培养液为 从膜分离罐的培养液流入侧的压力，允许从发酵罐转移到膜分离槽旁路。
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公开(公告)号：US20160145651A1
公开(公告)日：2016-05-26
申请号：US14903642
申请日：2014-07-08
CPC分类号： C12P7/14 , C12N1/22 , C12P7/10 , C12P19/02 , C12P19/14 , C12P2203/00 , C13B20/002 , C13B30/002 , C13B50/00 , C13K1/04 , C13K5/00 , C13K13/00 , C13K13/002 , Y02E50/16 , Y02E50/17
摘要： A method of producing a sugar liquid from biomass includes decomposing a fermentation inhibitor contained in a sugar aqueous solution obtained from biomass with a microorganism incapable of utilizing glucose and/or xylose or a crude enzyme derived from the microorganism, wherein the fermentation inhibitor includes one or more compounds selected from the group consisting of courmaric acid, coumaramide, ferulic acid, ferulamide, vanillin, vanillic acid, acetovanillone, furfural, and 3-hydroxymethylfurfural.
摘要翻译： 从生物质生产糖液的方法包括用不能使用葡萄糖和/或木糖的微生物或由微生物衍生的粗酶分解由生物质获得的糖水溶液中所含的发酵抑制剂，其中发酵抑制剂包括一种或 更多选自洋甘油酸，香豆素，阿魏酸，阿魏酰胺，香草醛，香草酸，乙酰乙one酮，糠醛和3-羟甲基糠醛的化合物。
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73.发明授权Mutant β-glucosidase, enzyme composition for decomposing biomass, and method of producing sugar solution 有权突变体 - 葡萄糖苷酶，用于分解生物质的酶组合物和产生糖溶液的方法公开(公告)号：US09080164B2
公开(公告)日：2015-07-14
申请号：US14154547
申请日：2014-01-14
发明人： Hiroyuki Kurihara , Katsushige Yamada , Kazuhiko Ishikawa , Yumiko Mishima , Yasunobu Wada , Yuji Kado
CPC分类号： C12N9/2445 , C12P19/02 , C12P19/14 , C12Y302/01021
摘要： A β-glucosidase exhibits high activity in the presence of biomass and has high thermal stability compared to conventional enzymes. The β-glucosidase includes substitutions and/or deletions of amino acids, at least three amino acids selected from the group consisting of Glu39, Asp169, Arg170, Arg220, Tyr227, and Glu330, of the parent β-glucosidase with other amino acids and exhibits a decomposition activity.
摘要翻译： 葡萄糖苷酶在生物质存在下表现出高活性，与常规酶相比具有高热稳定性。 β-葡糖苷酶包括氨基酸的取代和/或缺失，至少三种氨基酸，其选自亲本＆amp;葡糖苷酶与其它氨基酸的Glu39，Asp169，Arg170，Arg220，Tyr227和Glu330 并表现出分解活性。
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公开(公告)号：US20150167037A1
公开(公告)日：2015-06-18
申请号：US14412217
申请日：2013-07-01
CPC分类号： C12P19/14 , C12N9/2434 , C12N9/2437 , C12P19/02 , C13K1/02 , C13K1/04
摘要： A method of producing a sugar liquid from a cellulose-containing biomass includes (1) hydrolyzing a cellulose-containing biomass using a filamentous fungus-derived cellulose and carrying out solid-liquid separation into a sugar liquid and a hydrolysis residue; (2) washing the hydrolysis residue in (1) using an aqueous alkaline solution and an aqueous inorganic salt solution independently and recovering, as a washing liquid, the filamentous fungus-derived cellulase adsorbed to the hydrolysis residue; and (3) filtering the washing liquid in (2) through an ultrafiltration membrane to recover a sugar liquid as a permeate and the filamentous fungus-derived cellulase as a non-permeate.
摘要翻译： 从含纤维素生物质生产糖液的方法包括：（1）使用丝状真菌衍生的纤维素水解含纤维素的生物质并进行固液分离成糖液和水解残余物; （2）使用碱性水溶液和无机盐水溶液独立地洗涤（1）中的水解残余物，作为洗涤液回收吸附在水解残渣上的丝状真菌衍生的纤维素酶; （3）通过超滤膜过滤（2）中的洗涤液，回收作为渗透物的糖液和作为非渗透物的丝状真菌来源的纤维素酶。
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公开(公告)号：US20150147787A1
公开(公告)日：2015-05-28
申请号：US14405239
申请日：2013-06-04
CPC分类号： C13K1/04 , C12P7/56 , C12P19/02 , C12P19/14 , C12P2203/00 , C13K13/002
摘要： A method produces a sugar liquid from a cellulosic biomass material, which sugar liquid has improved fermentability. The method produces a sugar liquid by: adding an alkali(s) to a concentrated cellulosic biomass sugar liquid to adjust the pH to not less than 7 to precipitate an insoluble substance(s) containing at least magnesium; and performing filtration through a microfiltration membrane to remove the insoluble substance(s), to obtain a sugar liquid as a permeate.
摘要翻译： 一种方法从纤维素生物质材料产生糖液，该糖液具有改善的发酵能力。 该方法通过以下方式产生糖液：将一种或多种碱加入到浓缩的纤维素生物质糖液中以将pH调节至不小于7以沉淀至少含有镁的不溶性物质; 并通过微滤膜进行过滤以除去不溶物质，得到作为渗透物的糖液。
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公开(公告)号：US09024074B2
公开(公告)日：2015-05-05
申请号：US14374449
申请日：2013-01-23
IPC分类号： C07C45/66 , C07C45/69 , C07C1/22 , B01J23/26 , C07C1/207 , B01J23/42 , B01J23/44 , B01J23/46 , B01J23/72 , B01J23/745 , B01J23/755 , C07C45/65 , C07C45/61
CPC分类号： C07C45/69 , B01J23/26 , B01J23/42 , B01J23/44 , B01J23/462 , B01J23/72 , B01J23/745 , B01J23/755 , C07C1/207 , C07C1/22 , C07C45/61 , C07C45/65 , C07C2521/04 , C07C2521/08 , C07C2521/12 , C07C2521/18 , C07C2523/26 , C07C2523/42 , C07C2523/44 , C07C2523/46 , C07C2523/72 , C07C2523/745 , C07C2523/755 , C07C2601/16 , Y02P20/52 , C07C15/08 , C07C47/42 , C07C47/542
摘要： Disclosed is a method for producing p-xylene and/or p-tolualdehyde with high yield through a short process using biomass resource-derived substances as raw materials. The method for producing p-xylene and/or p-tolualdehyde of the present invention comprises: a cyclization step of producing 4-methyl-3-cyclohexenecarboxaldehyde from isoprene and acrolein; and an aromatization step of producing p-xylene and/or p-tolualdehyde from 4-methyl-3-cyclohexenecarboxaldehyde by gas-phase flow reaction using a catalyst(s).
摘要翻译： 公开了以生物质资源衍生物质为原料，通过短时间生产对二甲苯和/或对甲苯甲醛的方法。 本发明的对二甲苯和/或对甲苯甲醛的制造方法包括：从异戊二烯和丙烯醛生成4-甲基-3-环己烯甲醛的环化步骤; 以及通过使用催化剂的气相流动反应从4-甲基-3-环己烯甲醛生产对二甲苯和/或对甲苯甲醛的芳构化步骤。
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公开(公告)号：US20140238841A1
公开(公告)日：2014-08-28
申请号：US14350366
申请日：2012-10-12
发明人： Kenji Kawamura , Izumi Morita , Masateru Ito , Kyohei Isobe , Satoshi Sakami , Katsushige Yamada
IPC分类号： C07C29/80
摘要： A method of producing 2,3-butanediol includes subjecting a 2,3-butanediol culture liquid produced by microbial fermentation to nanofiltration membrane treatment and ion-exchange treatment (Step A), and then adding an alkaline substance and performing distillation (Step B).
摘要翻译： 制备2,3-丁二醇的方法包括将通过微生物发酵生产的2,3-丁二醇培养液进行纳滤膜处理和离子交换处理（步骤A），然后加入碱性物质进行蒸馏（步骤B） 。
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公开(公告)号：US12037624B2
公开(公告)日：2024-07-16
申请号：US17263685
申请日：2019-07-29
CPC分类号： C12P21/02 , C07K14/37 , C12N1/145 , C12R2001/885
摘要： A mutant of a trichoderma filamentous fungus has a mutation that results in lost or lowered function of a beta-adaptin large subunit, or a mutation in an amino acid sequence that forms the beta-adaptin large subunit. A method produces a protein while maintaining a low viscosity in a culture solution during culturing by using the mutant.
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公开(公告)号：US11760739B2
公开(公告)日：2023-09-19
申请号：US17439782
申请日：2020-03-24
IPC分类号： C07D307/33
CPC分类号： C07D307/33
摘要： A method relates to producing 3-hydroxyadipic acid-3,6-lactone, the method including the following steps (A) and (B): (A) a step of adding an acid to a 3-hydroxyadipic acid-containing aqueous solution to obtain a 3-hydroxyadipic acid-3,6-lactone-containing aqueous solution; and (B) a step of obtaining a 3-hydroxyadipic acid-3,6-lactone extract by bringing the 3-hydroxyadipic acid-3,6-lactone-containing aqueous solution obtained in step (A) into contact with an extraction solvent that is phase-separated from the solution.
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公开(公告)号：US11608493B2
公开(公告)日：2023-03-21
申请号：US17059821
申请日：2019-05-30
摘要： A mutant strain of a filamentous fungus of the genus Trichoderma having a reduced function of a polypeptide consisting of the amino acid sequence represented by SEQ ID NO: 2; and a method of producing a sugar from a cellulose-containing biomass, the method including: step a of producing a cellulase by cultivating a Trichoderma reesei mutant strain having a reduced function of a polypeptide consisting of the amino acid sequence represented by SEQ ID NO: 2, and step b of saccharifying the biomass by using the cellulase obtained in the step a.
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