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公开(公告)号:US20230277877A1
公开(公告)日:2023-09-07
申请号:US18125959
申请日:2023-03-24
Applicant: Alpheus Medical, Inc.
Inventor: Vijay AGARWAL , Braden ELIASON , Jeremy LING
CPC classification number: A61N7/00 , A61F7/0085 , A61K9/0053 , A61K31/197 , A61K41/0033 , A61K41/0061 , A61P35/00 , B06B1/0207 , B06B1/0622 , A61B2017/00084
Abstract: Methods of treating tumors by administering compounds to a patient are provided. Compounds such as drugs, may be administered to the patient orally, by injection, intravenously, or topically, which then accumulate preferentially as compounds such as protoporphyrin IX (PpIX) in tumor cells. After such accumulation, compounds such as PpIX are then activated in various aspects to treat tumors cells, thereby treating cancer. Cancers such as glioblastoma may be treated.
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公开(公告)号:US11744547B2
公开(公告)日:2023-09-05
申请号:US16066865
申请日:2017-02-23
Applicant: SUNNYBROOK RESEARCH INSTITUTE
Inventor: Kullervo Henrik Hynynen
CPC classification number: A61B8/4281 , A61B8/4488 , A61N7/00 , B06B3/00 , G01S7/52077 , G01S7/52079 , G01S15/8915 , G10K11/26 , A61N2007/0078
Abstract: An ultrasound phased array transducer is disclosed that achieves suppression of grating lobes through the incorporation of a coupling layer, where the coupling layer is positioned adjacent to the phased array transducer such that an ultrasound beam propagates through the coupling layer prior to encountering a propagation medium. The phased-array elements may be provided such that one or both of the array pitch and a lateral extent of each ultrasound transducer element is larger than half of the ultrasound wavelength in the propagation medium. Grating lobes within the coupling layer and the propagation medium may be reduced or suppressed by selecting a coupling material having a speed of sound that exceeds that of the propagation medium. The coupling layer may have a thickness sufficient for the generation of a wavefront, and the coupling layer may be formed from a viscous or viscoelastic material.
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公开(公告)号:US11737750B2
公开(公告)日:2023-08-29
申请号:US16779752
申请日:2020-02-03
Applicant: Cilag GmbH International
Inventor: Jeffrey L. Aldridge , Eitan T. Wiener , Robert A. Kemerling , James R. Giordano , Vincent P. Battaglia, Jr. , Daniel W. Price , Sean P. Conlon , Gregory W. Johnson , Jeffrey D. Messerly , Shan Wan , Kevin L. Houser , Foster B. Stulen , Jacob S. Gee , Jeffrey A. Bullock , John A. Hibner , William B. Weisenburgh, II
IPC: A61B17/072 , A61B18/14 , A61B17/00 , H01R13/66 , H01M50/209 , A61B17/32 , A61B18/00 , A61B18/12 , A61B17/29 , A61N7/00
CPC classification number: A61B17/07207 , A61B17/00234 , A61B18/1445 , H01M50/209 , H01R13/6675 , A61B2017/00017 , A61B2017/00026 , A61B2017/0046 , A61B2017/00115 , A61B2017/00119 , A61B2017/00221 , A61B2017/00225 , A61B2017/00398 , A61B2017/00411 , A61B2017/00464 , A61B2017/00734 , A61B2017/2927 , A61B2017/320093 , A61B2017/320094 , A61B2017/320095 , A61B2017/320097 , A61B2018/00791 , A61B2018/1226 , A61B2560/0443 , A61N7/00 , H01M2220/30 , H01R2201/12
Abstract: A surgical instrument includes a body, a shaft assembly, and an end effector. The shaft assembly extends distally from the body. The end effector is located at a distal end portion of the shaft assembly. The end effector includes an active feature configured to operate on tissue. The body includes a drive feature operable to drive the active feature of the end effector. The body is removably coupled with the shaft assembly in a connected state and separated from the shaft assembly in a disconnected state. The body includes a drive feature configured to drive operation of the active feature of the effector. The drive feature includes at least one of an ultrasonic drive feature or a mechanical drive feature. A proximal end portion of the shaft assembly is configured to be removed from the body to separate the at least one activation feature from the drive feature.
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公开(公告)号:US20230249006A1
公开(公告)日:2023-08-10
申请号:US18129680
申请日:2023-03-31
Applicant: The Board of Trustees of the Leland Stanford Junior University Office of the General Counsel
Inventor: Butrus T. Khuri-Yakub , Kwan Kyu Park , Kamyar Firouzi , Younghun Kim
IPC: A61N7/00
CPC classification number: A61N7/00 , A61N2007/0026 , A61N2007/0078
Abstract: Improved acoustic neurostimulation is provided using two or more acoustic transducers generating an acoustic interference pattern. In a first operating mode the transducers are driven at the same frequency. In a second operating mode the transducers are driven at different frequencies. The acoustic interference pattern is varied electronically by control of the driving frequencies. In addition, a method for neurostimulation excites two confocal ultrasound transducers using an excitation waveform signal that has a time-varying frequency within range containing a resonance frequency of the two transducers, thereby increasing resolution and allowing electronic scanning.
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公开(公告)号:US20230249004A1
公开(公告)日:2023-08-10
申请号:US17665743
申请日:2022-02-07
Applicant: Moshe Ein-Gal
Inventor: Moshe Ein-Gal
IPC: A61N7/00
CPC classification number: A61N7/00 , A61N2007/0034 , A61N2007/0065 , A61N2007/0078
Abstract: A method and device for skin or deeper organ treatment uses an applicator that includes a transducer for producing beams of pressure waves and a coupler for coupling the pressure waves to the skin or deeper organ. The pressure waves in the skin and deeper propagate in directions generally extending at small angles relative to the skin surface
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公开(公告)号:US20230241405A1
公开(公告)日:2023-08-03
申请号:US18182663
申请日:2023-03-13
Applicant: BTL Medical Solutions A.S.
Inventor: Tomás SCHWARZ , Ondra PROUZA
IPC: A61N2/00 , A61B18/20 , A61F7/00 , A61N1/06 , A61N1/40 , A61N2/02 , A61N5/06 , A61N7/00 , A61B90/50
CPC classification number: A61N2/004 , A61B18/203 , A61F7/00 , A61N1/06 , A61N1/40 , A61N2/002 , A61N2/02 , A61N5/0613 , A61N5/0622 , A61N5/0624 , A61N5/0625 , A61N7/00 , A61B90/50 , A61N2007/0034 , A61N5/067
Abstract: A device for enhancement of visual appearance including a first applicator to be coupled to a first area of a body region, with a first magnetic field generating device and a first radiofrequency electrode, a second applicator to be coupled to a second area of the body region, with a second magnetic field generating device. The device further includes a first energy storage device, a second energy storage device, and a first switching device to discharge energy from the first energy storage device to the first magnetic field generating to generate a first time-varying magnetic field to cause muscle contraction, and a second switching to discharge energy from the second energy storage device to the second magnetic field generating device to generate a second time-varying magnetic field. The first radiofrequency electrode may provide first radiofrequency waves causing heating of tissue within the first area of the body region.
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公开(公告)号:US11712283B2
公开(公告)日:2023-08-01
申请号:US16842062
申请日:2020-04-07
Applicant: Nuvaira, Inc.
Inventor: Martin L. Mayse , Steven C. Dimmer
IPC: A61B18/08 , A61B17/00 , A61N5/06 , A61B18/14 , A61B18/18 , A61B18/04 , A61N7/00 , A61N5/10 , A61N7/02 , A61B18/02 , A61B18/00
CPC classification number: A61B18/082 , A61B17/00234 , A61B18/04 , A61B18/1492 , A61B18/18 , A61B18/1815 , A61N5/0601 , A61N5/062 , A61N5/1077 , A61N7/00 , A61N7/022 , A61B18/02 , A61B18/1477 , A61B2017/00323 , A61B2018/0022 , A61B2018/00279 , A61B2018/00291 , A61B2018/00434 , A61B2018/00541 , A61B2018/00577 , A61B2018/00642 , A61B2018/00982 , A61B2018/0212 , A61B2018/1425 , A61B2018/1861 , A61N2005/0604 , A61N2005/0651 , A61N2007/003
Abstract: A system and method can be used to denervate at least a portion of a bronchial tree. An energy emitter of an instrument is percutaneously delivered to a treatment site and outputs energy to damage nerve tissue of the bronchial tree. The denervation procedure can be performed without damaging non-targeted tissue. Minimally invasive methods can be used to open airways to improve lung function in subjects with COPD, asthma, or the like. Different sections of the bronchial tree can be denervated while leaving airways intact to reduce recovery times.
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公开(公告)号:US11712226B2
公开(公告)日:2023-08-01
申请号:US17410364
申请日:2021-08-24
Inventor: Anshuman Bhuyan , Jung Woo Choe , Amin Nikoozadeh , Butrus T. Khuri-Yakub
CPC classification number: A61B8/54 , A61B8/4483 , A61N7/00 , A61N7/02 , B06B1/0215 , B06B1/0292 , A61N2007/0021 , A61N2007/0052 , B06B2201/76
Abstract: Ultrasound imaging and therapy with the same array of capacitive micromachined ultrasonic transducers is provided. The electronics includes a per-pixel switch for each transducer element. The switches provide an imaging mode driven completely by on-chip electronics and a therapy mode where off-chip pulsers provide relatively high voltages to the transducer elements.
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公开(公告)号:US20230233220A1
公开(公告)日:2023-07-27
申请号:US18127807
申请日:2023-03-29
Applicant: MEDTRONIC INC.
Inventor: ALAN CHEN , JIAN CAO , ZHONGPING YANG
CPC classification number: A61B17/22012 , A61N1/0573 , A61N7/00 , A61N2007/0004 , A61N1/3956
Abstract: A surgical method treats infections on a lead positioned at least partially within a patient's body. The surgical method includes uncoupling the lead from a pulse generator. The lead is then coupled to an ultrasound wave generator. Ultrasound waves are propagated from the ultrasound wave generator through the lead. Systems are disclosed.
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公开(公告)号:US20230218275A1
公开(公告)日:2023-07-13
申请号:US18180466
申请日:2023-03-08
Applicant: Shanghai Shende Green Medical Era Healthcare Technology Co., Ltd. , Shende (Ningbo) Medical Device Technology Co., Ltd , Nantong Shende Medical Device Technology Co., Ltd
Inventor: Bo YANG , Shengfa ZHANG , Jiawei GU , Jiabao WEN , Junjie GUO , Bo WEI , Hao WU , Zihao LIU , Zhiqiang SU
Abstract: Disclosed is a method for controlling a focused ultrasound therapy device based on an Acorn RISC Machine, the focused ultrasound therapy device being connected to a workstation and an ARM embedded processor running a linux operating system, the ARM embedded processor storing a first control program, the workstation storing a second control program, the method including: the first control program controlling the focused ultrasound therapy device by executing a task and sending a task execution result to the second control program; the task includes an internal event and an operation instruction, the internal event includes a timer event of the first control program and an interrupt message of a linux kernel, the second control program receives the operation instruction through the workstation and sends the operation instruction to the first control program.
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