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81.发明授权System, devices, and methods including actively-controllable superoxide water generating systems 有权系统，装置和方法，包括主动控制的超氧水生成系统公开(公告)号：US08162924B2
公开(公告)日：2012-04-24
申请号：US12315880
申请日：2008-12-04
申请人： Edward S. Boyden , Ralph G. Dacey, Jr. , Gregory J. Della Rocca , Joshua L. Dowling , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Paul Santiago , Michael A. Smith , Todd J. Stewart , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, Jr. , Victoria Y. H. Wood
发明人： Edward S. Boyden , Ralph G. Dacey, Jr. , Gregory J. Della Rocca , Joshua L. Dowling , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Paul Santiago , Michael A. Smith , Todd J. Stewart , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, Jr. , Victoria Y. H. Wood
IPC分类号： A61K9/22
CPC分类号： A61L2/0011 , A61L2/08 , A61L2/14
摘要： Systems, devices, methods, and compositions are described for providing an actively-controllable disinfecting implantable device configured to, for example, treat or prevent an infection in a biological subject.
摘要翻译： 描述了用于提供主动控制的消毒可植入装置的系统，装置，方法和组合物，其被配置为例如治疗或预防生物学对象中的感染。
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公开(公告)号：US08125093B2
公开(公告)日：2012-02-28
申请号：US12587407
申请日：2009-10-05
申请人： Roderick A. Hyde , William H. Gates, III , Muriel Y. Ishikawa , Jordin T. Kare , Nathan P. Myhrvold , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood, Jr. , Victoria Y. H. Wood
发明人： Roderick A. Hyde , William H. Gates, III , Muriel Y. Ishikawa , Jordin T. Kare , Nathan P. Myhrvold , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood, Jr. , Victoria Y. H. Wood
IPC分类号： H02K33/00
CPC分类号： F02B63/04 , B60L3/0023 , B60L11/005 , B60L11/14 , B60L11/1861 , B60L15/2009 , B60L2210/40 , B60L2220/12 , B60L2220/14 , B60L2240/12 , B60L2240/14 , B60L2240/36 , B60L2240/421 , B60L2240/423 , B60L2240/429 , B60L2240/441 , B60L2240/445 , B60L2240/642 , B60L2240/662 , B60L2250/26 , B60L2270/12 , F01B9/047 , F02B71/04 , F02B75/28 , F02B75/32 , Y02T10/645 , Y02T10/70 , Y02T10/7005 , Y02T10/7022 , Y02T10/7044 , Y02T10/705 , Y02T10/7077 , Y02T10/7241 , Y02T10/7275 , Y02T10/7291 , Y02T90/16
摘要： A converter converts mechanical energy of a piston to and from electrical energy during each piston cycle.
摘要翻译： A转换器在每个活塞循环期间将活塞的机械能转换为电能和来自电能。
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公开(公告)号：US08037852B2
公开(公告)日：2011-10-18
申请号：US12804426
申请日：2010-07-20
申请人： Roderick A. Hyde , William H. Gates, III , Muriel Y. Ishikawa , Jordin T. Kare , Nathan P. Myhrvold , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood, Jr. , Victoria Y. H. Wood
发明人： Roderick A. Hyde , William H. Gates, III , Muriel Y. Ishikawa , Jordin T. Kare , Nathan P. Myhrvold , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood, Jr. , Victoria Y. H. Wood
IPC分类号： F02B71/00
CPC分类号： H02K7/1884 , B60L7/14 , B60L11/005 , B60L11/14 , B60L15/2009 , B60L2210/40 , B60L2220/12 , B60L2220/14 , B60L2240/12 , B60L2240/14 , B60L2240/36 , B60L2240/421 , B60L2240/429 , B60L2240/441 , B60L2240/642 , B60L2240/662 , B60L2270/12 , F02B63/04 , F02B63/041 , Y02T10/641 , Y02T10/645 , Y02T10/70 , Y02T10/7022 , Y02T10/7077 , Y02T10/7241 , Y02T10/7275 , Y02T10/7291 , Y02T90/16
摘要： Methods of operating an internal combustion engine are disclosed that may include a first piston slidably disposed in a first cylinder having a first and a second closed end, and a first converter operable with the first cylinder. The first converter may be configured to convert mechanical energy to electrical energy, and vice versa. As a non-limiting example, such disclosed embodiments may be used to convert mechanical energy of the first piston to electrical energy during a power stroke, and to drive the first piston during one or more of an exhaust stroke, an intake stroke, or a compression stroke.
摘要翻译： 公开了操作内燃机的方法，其可以包括可滑动地设置在具有第一和第二封闭端的第一气缸中的第一活塞和可与第一气缸一起操作的第一转换器。 第一转换器可以被配置为将机械能转换成电能，反之亦然。 作为非限制性示例，这样公开的实施例可以用于在功率冲程期间将第一活塞的机械能转换为电能，并且在排气冲程，进气冲程或者排气冲程中的一个或多个期间驱动第一活塞 压缩冲程。
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84.发明申请Systems, devices, and methods including catheters configured to release ultraviolet energy absorbing agents 审中-公开包括构造成释放紫外线能量吸收剂的导管的系统，装置和方法公开(公告)号：US20110160644A1
公开(公告)日：2011-06-30
申请号：US12927295
申请日：2010-11-10
申请人： Ralph G. Dacey, JR. , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y. H. Wood
发明人： Ralph G. Dacey, JR. , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y. H. Wood
IPC分类号： A61M37/00
CPC分类号： A61L2/0011 , A61F2/32 , A61F2002/30087 , A61F2002/3067 , A61F2002/30677 , A61F2002/48 , A61F2002/481 , A61F2002/482 , A61F2250/0002 , A61F2310/0097 , A61L2202/14 , A61L2202/24 , A61N1/205 , A61N1/37252 , A61N1/3785 , A61N1/3787
摘要： Systems, devices, methods, and compositions are described for providing an actively-controllable disinfecting implantable device configured to, for example, treat or prevent an infection in a biological subject.
摘要翻译： 描述了用于提供主动控制的消毒可植入装置的系统，装置，方法和组合物，其被配置为例如治疗或预防生物学对象中的感染。
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公开(公告)号：US07950356B2
公开(公告)日：2011-05-31
申请号：US11973640
申请日：2007-10-09
申请人： Roderick A. Hyde , William H. Gates, III , Muriel Y. Ishikawa , Jordin T. Kare , Nathan P. Myhrvold , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood, Jr. , Victoria Y. H. Wood
发明人： Roderick A. Hyde , William H. Gates, III , Muriel Y. Ishikawa , Jordin T. Kare , Nathan P. Myhrvold , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood, Jr. , Victoria Y. H. Wood
IPC分类号： F02B71/00
CPC分类号： F02B63/04 , F02B63/041 , F02B71/04 , F02B75/021 , F02B75/04 , F02B75/042 , F02B75/048 , F02B75/28 , H02K7/1884 , H02K35/02
摘要： In an embodiment, an internal combustion engine includes a first cylinder having a first piston and a second piston slidably disposed therein, an intake port arranged to admit a reactant into the first cylinder between the first and second pistons, and an exhaust port axially spaced from the intake port and arranged to exhaust a reaction product from the first cylinder. First and second converters are provided, which are operable with the corresponding first and second pistons, to convert mechanical energy of the first and second pistons to electrical energy and electrical energy to mechanical energy. A control system is provided that is coupled to the first and second converters. The control system is configured to control the application of electrical energy to the first and second converters to selectively position the first and second pistons during specific strokes of the engine cycle.
摘要翻译： 在一个实施例中，内燃机包括具有第一活塞和可滑动地设置在其中的第二活塞的第一气缸，设置成允许反应物进入第一和第二活塞之间的第一气缸的进气口和与第一气缸轴向间隔开的排气口 所述进气口布置成从所述第一气缸排出反应产物。 提供第一和第二转换器，其可与相应的第一和第二活塞一起操作，以将第一和第二活塞的机械能转换为电能和电能至机械能。 提供了耦合到第一和第二转换器的控制系统。 控制系统被配置为控制对第一和第二转换器的电能的施加，以在发动机循环的特定冲程期间选择性地定位第一和第二活塞。
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公开(公告)号：US09617157B2
公开(公告)日：2017-04-11
申请号：US12322367
申请日：2009-01-30
申请人： Mahalaxmi Gita Bangera , Ed Harlow , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, Jr. , Victoria Y. H. Wood
发明人： Mahalaxmi Gita Bangera , Ed Harlow , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, Jr. , Victoria Y. H. Wood
CPC分类号： C07K16/32 , A61K38/1703 , A61K38/1732 , A61K47/60 , A61K47/6871 , A61K47/6901 , B82Y5/00 , B82Y15/00 , B82Y30/00 , B82Y40/00 , C01B21/0648 , C01B32/168 , C01B32/174 , C01B2202/02 , C01B2202/34 , C01B2202/36 , C01P2004/13 , Y02A50/473 , Y10S977/743 , Y10S977/75 , Y10S977/762 , Y10S977/788 , Y10S977/795 , Y10S977/848 , Y10S977/896 , Y10S977/915
摘要： Devices, compositions, and methods are described which provide a tubular nanostructure or a composite tubular nanostructure targeted to a lipid bilayer membrane. The tubular nanostructure includes a hydrophobic surface region flanked by two hydrophilic surface regions. The tubular nanostructure is configured to interact with a lipid bilayer membrane and form a pore in the lipid bilayer membrane. The tubular nanostructure may be targeted by including at least one ligand configured to bind to one or more cognates on the lipid bilayer membrane of a target cell.
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公开(公告)号：US08684898B2
公开(公告)日：2014-04-01
申请号：US12012218
申请日：2008-01-30
申请人： Edward S. Boyden , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Nathan P. Myhrvold , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood, Jr. , Victoria Y. H. Wood
发明人： Edward S. Boyden , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Nathan P. Myhrvold , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood, Jr. , Victoria Y. H. Wood
IPC分类号： A61N5/00
CPC分类号： C09K11/06 , A61K9/0009
摘要： A method composition and system respond to ionizing, radiation to adjust biological activity. In some approaches the ionizing radiation is X-ray or extreme ultraviolet radiation that produces luminescent responses that induce biologically active responses.
摘要翻译： 一种方法组成和系统响应电离，辐射来调节生物活性。 在一些方法中，电离辐射是产生引发生物活性反应的发光反应的X射线或极紫外辐射。
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公开(公告)号：US08529426B2
公开(公告)日：2013-09-10
申请号：US12012220
申请日：2008-01-30
申请人： Edward S. Boyden , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Nathan P. Myhrvold , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood, Jr. , Victoria Y. H. Wood
发明人： Edward S. Boyden , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Nathan P. Myhrvold , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood, Jr. , Victoria Y. H. Wood
IPC分类号： A61N5/00
CPC分类号： A61K41/0057
摘要： A method, composition and system respond to ionizing radiation to adjust biological activity. In some approaches the ionizing radiation is X-ray or extreme ultraviolet radiation that produces luminescent responses that induce biologically active responses.
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公开(公告)号：US08164074B2
公开(公告)日：2012-04-24
申请号：US11975702
申请日：2007-10-18
申请人： Edward S. Boyden , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Nathan P. Myhrvold , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood, Jr. , Victoria Y. H. Wood
发明人： Edward S. Boyden , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Nathan P. Myhrvold , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood, Jr. , Victoria Y. H. Wood
IPC分类号： G01N21/64
CPC分类号： A61K41/0057 , A61K41/0019 , A61K41/0042
摘要： A method, composition and system respond to ionizing radiation to adjust biological activity. In some approaches the ionizing radiation is X-ray or extreme ultraviolet radiation that produces luminescent responses that induce biologically active responses.
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公开(公告)号：US20120035440A1
公开(公告)日：2012-02-09
申请号：US13136680
申请日：2011-08-05
申请人： Bran Ferren , W. Daniel Hillis , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Eric C. Leuthardt , Nathan P. Myhrvold , Thomas J. Nugent, JR. , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y. H. Wood
发明人： Bran Ferren , W. Daniel Hillis , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Eric C. Leuthardt , Nathan P. Myhrvold , Thomas J. Nugent, JR. , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y. H. Wood
IPC分类号： A61B5/07
CPC分类号： A61B1/041 , A61B1/00156 , A61B5/0022 , A61B5/0031 , A61B5/0071 , A61B5/01 , A61B5/02007 , A61B5/0215 , A61B5/026 , A61B5/03 , A61B5/062 , A61B5/07 , A61B5/073 , A61B5/076 , A61B5/082 , A61B5/14539 , A61B5/14546 , A61B5/4064 , A61B5/411 , A61B5/418 , A61B5/4839 , A61B5/6852 , A61B7/00 , A61B10/0045 , A61B10/04 , A61B17/22 , A61B17/22012 , A61B18/20 , A61B34/73 , A61B2010/0077 , A61B2010/0225 , A61B2017/00022 , A61B2017/00345 , A61F2/82 , A61N1/406 , A61N7/00 , G06F19/00 , G16H40/67
摘要： Methods of controlling the operation of a device traveling in a body tube tree, including sensing parameters from possible directions of travel and selecting the direction of travel based on the sensed parameters, implemented with a control system located partially or fully on the lumen traveling device. Various actions can be performed by the device for, e.g., medical or therapeutic purposes. Machine-readable media including instructions for performing the methods are also described.
摘要翻译： 控制在体管树中行进的装置的操作的方法，包括从可能的行进方向感测参数以及基于所感测的参数来选择行进方向，所述方法由部分地或完全位于流明行进装置上的控制系统实现。 可以通过该设备执行各种动作，例如医疗或治疗目的。 还描述了包括用于执行方法的指令的机器可读介质。
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