利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

110 条记录 (耗时 0.031 秒)

    Process for producing dipeptide,l-amino acid amide hydrolase to be used therein and process for producing l-amino acid amide hydrolase
    81.
    发明申请
    Process for producing dipeptide,l-amino acid amide hydrolase to be used therein and process for producing l-amino acid amide hydrolase 失效
    用于生产二肽，用于其中的1-氨基酰胺水解酶的方法和用于生产1-氨基酸酰胺水解酶的方法

    公开(公告)号：US20050054067A1

    公开(公告)日：2005-03-10

    申请号：US10481087

    申请日：2002-07-26

    申请人： Hiroyuki Nozaki ,  Ikuo Kira ,  Sonoko Suzuki ,  Kenzo Yokozeki

    发明人： Hiroyuki Nozaki ,  Ikuo Kira ,  Sonoko Suzuki ,  Kenzo Yokozeki

    IPC分类号： C07K5/062 ,  C07K5/06 ,  C12N1/19 ,  C12N1/21 ,  C12N9/00 ,  C12N9/48 ,  C12N9/52 ,  C12N9/80 ,  C12N15/57 ,  C12N15/63 ,  C12P21/00 ,  C12P21/02 ,  C12P21/06 ,  C12P1/02

    CPC分类号： C12P21/02 ,  C07K5/06026 ,  C12N9/48

    摘要： A process for industrially advantageously producing a dipeptide via a convenient pathway starting with less expensive and easily available materials is provided. A dipeptide is produced from an L-amino acid amide and an L-amino acid by using a culture of a microbe capable of synthesizing the dipeptide from the L-amino acid amide and the L-amino acid, microbial cells separated from the culture or a treated microbial cell product from the microbe. An L-amino acid amide hydrolase is obtained from a microbe belonging to the genus erwinia, genus Rhodococcus, genus Chryseobacterium, genus Micrococcus, genus Cryptococcus, genus Trichosporion, genus Rhodosporidium, genus Sporobolomyces, genus Tremela, genus Torulaspora, genus Sterigmatomyces or genus Rhodotorula. The hydrolase catalyzes a reaction that produces a dipeptide from an L-amino acid amide and an L-amino acid.

    摘要翻译： 提供了一种工业上有利地通过便宜的途径产生二肽的方法，从较便宜且容易获得的材料开始。 通过使用能够从L-氨基酸酰胺和L-氨基酸合成二肽的微生物培养物从L-氨基酸酰胺和L-氨基酸产生二肽，从培养物分离的微生物细胞或 来自微生物的经处理的微生物细胞产物。 L-氨基酸酰胺水解酶是从属于欧文氏菌属，红球菌属，巧克氏杆菌属，微球菌属，隐球菌属，三孢球菌属，红球菌属，孢子属，金龟子属，紫花a属，紫锥体属或红酵母属的微生物 。 该水解酶催化从L-氨基酸酰胺和L-氨基酸产生二肽的反应。

    Microorganisms and method for producing xylitol or d-xylulose
    83.
    发明授权
    Microorganisms and method for producing xylitol or d-xylulose 失效
    微生物和生产木糖醇或D-木酮糖的方法

    公开(公告)号：US06335177B1

    公开(公告)日：2002-01-01

    申请号：US09347001

    申请日：1999-07-02

    申请人： Yasuhiro Mihara ,  Sonoko Takeuchi ,  Yasuko Jojima ,  Naoto Tonouchi ,  Ryosuke Fudou ,  Kenzo Yokozeki

    发明人： Yasuhiro Mihara ,  Sonoko Takeuchi ,  Yasuko Jojima ,  Naoto Tonouchi ,  Ryosuke Fudou ,  Kenzo Yokozeki

    IPC分类号： C12P100

    CPC分类号： C12R1/01 ,  C12P7/06 ,  C12P7/18 ,  C12P19/02 ,  Y02E50/17

    摘要： According to the present invention, there are provided microorganisms having an ability to producing xylitol or D-xylulose by fermentation, and a method for producing xylitol or D-xylulose using the microorganisms. Osmophilic microorganisms were collected from soil, and the obtained microorganisms were searched for a bacterium having an ability to produce xylitol or D-xylulose from glucose. Xylitol or D-xylulose is produced by culturing an isolated bacterium in a suitable medium to accumulate xylitol or D-xylulose in the medium, and collecting xylitol or D-xylulose from the medium.

    摘要翻译： 根据本发明，提供了通过发酵生产木糖醇或D-木酮糖的能力的微生物，以及使用微生物生产木糖醇或D-木酮糖的方法。 从土壤中收集渗透性微生物，并从所得微生物中搜索具有从葡萄糖产生木糖醇或D-木酮糖的能力的细菌。 通过在合适的培养基中培养分离的细菌以在培养基中积累木糖醇或D-木酮糖并从培养基中收集木糖醇或D-木酮糖来生产木糖醇或D-木酮糖。

    MUTANT MICROORGANISM AND METHOD FOR PRODUCING PEPTIDE USING THE SAME
    85.
    发明申请
    MUTANT MICROORGANISM AND METHOD FOR PRODUCING PEPTIDE USING THE SAME 审中-公开
    突变微生物及使用其生产肽的方法

    公开(公告)号：US20120058511A1

    公开(公告)日：2012-03-08

    申请号：US12828772

    申请日：2010-07-01

    申请人： Ikuo KIRA ,  Kenzo Yokozeki ,  Sonoko Suzuki ,  Yasuhiro Mihara ,  Yoshinori Hirao

    发明人： Ikuo KIRA ,  Kenzo Yokozeki ,  Sonoko Suzuki ,  Yasuhiro Mihara ,  Yoshinori Hirao

    IPC分类号： C12N1/21 ,  C12P21/00

    CPC分类号： C12N9/88 ,  C12N15/74

    摘要： The present invention provides a method for producing the peptides comprising: cultivating in medium the microorganisms wherein at least one gene selected from the group consisting of a gene encoding; aminoacylhistidine peptidase; a gene encoding leucylaminopeptidase; and a gene encoding isoaspartyldipeptidase, respectively; has been disrupted on the chromosome and wherein preferably transformed with the recombinant DNA, comprising polynucleotide encoding the proteins having peptide-synthesizing activity, mixing at least one of the cultivated microorganisms and the disrupted cells of the microorganisms with the carboxy and amine components for the peptide synthesis.

    摘要翻译： 本发明提供了一种生产肽的方法，包括：在培养基中培养微生物，其中至少一种选自下组的基因：基因编码; 氨酰基组氨酸肽酶; 编码亮氨酰氨基肽酶的基因; 和分别编码异天竺葵酰二肽酶的基因; 已经在染色体上被破坏，并且其中优选用重组DNA转化，包括编码具有肽合成活性的蛋白质的多核苷酸，将至少一种培养的微生物和微生物的破坏细胞与肽的羧基和胺组分混合 合成。

    Method for producing xylitol or D-xylulose in bacteria
    87.
    发明授权
    Method for producing xylitol or D-xylulose in bacteria 失效
    在细菌中生产木糖醇或D-木酮糖的方法

    公开(公告)号：US06221634B1

    公开(公告)日：2001-04-24

    申请号：US09487308

    申请日：2000-01-19

    申请人： Sonoko Takeuchi ,  Naoto Tonouchi ,  Kenzo Yokozeki

    发明人： Sonoko Takeuchi ,  Naoto Tonouchi ,  Kenzo Yokozeki

    IPC分类号： C12P1900

    CPC分类号： C12P7/18 ,  C12P19/02

    摘要： Xylitol or D-xylulose is produced through direct fermentation from glucose by culturing a microorganism belonging to the genus Gluconobacter, Acetobacter or Frateuria, and having an ability to produce xylitol or D-xylulose in a suitable medium to accumulate xylitol or D-xylulose in the medium, and collecting xylitol or D-xylulose from the medium.

    摘要翻译： 木糖醇或D-木酮糖通过葡萄糖直接发酵生产，通过培养属于葡糖酸杆菌属，醋酸杆菌属或葡萄糖酵母属的微生物，并且具有在合适的培养基中生产木糖醇或D-木酮糖以在木糖醇或D-木酮糖中积累木糖醇或D-木酮糖的能力 培养基，并从培养基中收集木糖醇或D-木酮糖。

    Process for producing D-malic acid
    89.
    发明授权
    Process for producing D-malic acid 失效
    D-苹果酸的生产方法

    公开(公告)号：US5824449A

    公开(公告)日：1998-10-20

    申请号：US840448

    申请日：1997-04-18

    申请人： Norimasa Ohnishi ,  Chisa Niwa ,  Kenzo Yokozeki

    发明人： Norimasa Ohnishi ,  Chisa Niwa ,  Kenzo Yokozeki

    IPC分类号： C12P7/46

    CPC分类号： C12P7/46 ,  Y10S435/822 ,  Y10S435/847 ,  Y10S435/901 ,  Y10S435/911

    摘要： A process for producing D-malic acid selectively without producing L-malic acid, using inexpensive maleic acid as a starting material, may be carried out using a microorganism belonging to the genus Erwinia, Mycoplana, Sporosarcina, Vibrio, Geotrichum or Torulaspora. The microorganism may be separated from the culture, used as a culture, or a treated microorganism.

    摘要翻译： 可以使用廉价的马来酸作为起始原料选择性地生产D-苹果酸而不生产L-苹果酸的方法可以使用属于欧文氏菌属，支原体属，孢子菌属，弧菌属，地衣芽孢杆菌属或孢子虫属的微生物进行。 微生物可以与用作培养物的培养物或经处理的微生物分离。