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公开(公告)号：US10128488B2
公开(公告)日：2018-11-13
申请号：US14768692
申请日：2014-02-27
发明人： Candace Chan
IPC分类号： H01M4/131 , H01M4/58 , H01M10/0525 , H01M10/054 , H01M4/485 , H01M4/02
摘要： An anode for a rechargeable battery includes a Type II clathrate having the formula MxX136, where a cage structure is formed by X, M represents one or more guest ions, and 0
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公开(公告)号：US10078074B2
公开(公告)日：2018-09-18
申请号：US14761732
申请日：2014-01-21
申请人： Francis Tsow , Xiaojun Xian , Erica Forzani , Nongjian Tao , ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY
发明人： Francis Tsow , Xiaojun Xian , Erica Forzani , Nongjian Tao
IPC分类号： A61B5/083 , A61B5/0482 , A61B5/087 , G01N33/497 , A61B5/00 , A61B5/08
CPC分类号： G01N33/497 , A61B5/0482 , A61B5/0816 , A61B5/083 , A61B5/087 , A61B5/7405
摘要： A system for measuring and tracking metabolic rate, physical activity and calorie intake. The metabolic rate is measured with a design that features an adaptive sampling mechanism for accurate breath sample collection, optimized flow rate measurement for minimizing backpressure while maximizing accuracy, humidity regulation and water condensation reduction mechanism for reliable performance, as well as breath temperature measurement for volume and humidity corrections. The system further comprises an improved algorithm for determining physical activity such as related energy expenditure, and a mechanism for tracking changes in food intake over time.
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3.发明授权Bispecific antibody fragments for neurological disease proteins and methods of use 有权用于神经疾病蛋白质的双特异性抗体片段和使用方法公开(公告)号：US09512212B2
公开(公告)日：2016-12-06
申请号：US14370199
申请日：2013-01-10
发明人： Michael Sierks , Yong Shen
IPC分类号： G01N33/541 , G01N33/563 , G01N33/577 , C07K16/46 , C07K16/18 , C07K16/28 , C07K16/40 , C07K16/42 , A61K39/00
CPC分类号： C07K16/18 , A61K2039/505 , C07K16/283 , C07K16/40 , C07K16/42 , C07K2317/31 , C07K2317/622 , C07K2317/626 , C07K2317/734 , C07K2317/76 , C07K2317/92 , C07K2319/02 , C07K2319/21 , C07K2319/41
摘要： The present invention relates to therapeutic agents comprising bispecific recombinant antibody fragments to selectively clear a protein associated with a neurological disease and methods of use of these therapeutic agents to treat neurological diseases.
摘要翻译： 本发明涉及包含双特异性重组抗体片段的治疗剂，其选择性地清除与神经疾病相关的蛋白质以及使用这些治疗剂治疗神经疾病的方法。
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公开(公告)号：US10370679B2
公开(公告)日：2019-08-06
申请号：US15289297
申请日：2016-10-10
申请人： Arizona Board of Regents, a body corporate of the State of Arizona acting for and on behalf of Arizona State University , Consejo Superior De Investigaciones Cientificas , IPPOX Foundation
发明人： Giuseppe Pantaleo , Thierry Calandra , Alexandre Harari , Thierry Roger , Mariano Esteban , Bertram Jacobs , Karen Kibler , Cornelius Melief , Rafick-Pierre Sekaly , Elias El Haddad , James Tartaglia
IPC分类号： A61K39/275 , A61K39/295 , A61K39/12 , C12N15/86 , A61K49/00 , A61K39/00
摘要： The disclosure relates to recombinant vectors and methods for using the same. In certain embodiments, the recombinant vectors are immunogenic.
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公开(公告)号：US09941089B2
公开(公告)日：2018-04-10
申请号：US15517917
申请日：2015-10-13
CPC分类号： H01J27/022 , H01H3/02 , H01J27/22 , H01J49/0004 , H01J49/26 , H03L7/26
摘要： A primary ion source subassembly for use with a secondary ion mass spectrometer may include a unitary graphite ionizer tube and reservoir base. A primary ion source may include a capillary insert defining an ionizer aperture. An ionizer aperture may be centrally arranged in an outwardly protruding conical or frustoconical surface, and may be overlaid with a refractory metal coating or sheath. Parameters including ionizer surface shape, ionizer materials, ionizer temperature, and beam stop plate orifice geometry may be manipulated to eliminate ghost images. A graphite tube gasket with a dual tapered surface may promote sealing of a source material cavity.
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公开(公告)号：US09700712B2
公开(公告)日：2017-07-11
申请号：US13735716
申请日：2013-01-07
发明人： Bruce C Towe
CPC分类号： A61N1/05 , A61N1/3605 , A61N1/37205 , A61N1/37223 , A61N1/3787 , H01P11/00 , H01Q9/00 , Y10T29/49018
摘要： Some embodiments include a dipolar antenna system to electrically power an implantable miniature device and/or to stimulate bioelectrically excitable tissue, such as, for example, through microelectronic neurostimulation. Other related systems and methods are also disclosed.
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公开(公告)号：US09289787B2
公开(公告)日：2016-03-22
申请号：US13680255
申请日：2012-11-19
发明人： R. Bruce Doak , John Spence , Uwe Weierstall , Daniel P. DePonte
IPC分类号： B05B17/00 , A62C5/02 , B05B7/04 , H01J49/16 , B05B7/06 , B05B7/08 , B05B1/02 , B05B1/00 , B01L3/02 , G01N23/22
CPC分类号： B05B7/0416 , B01L3/0268 , B01L2200/12 , B01L2300/0838 , B05B1/00 , B05B1/02 , B05B7/04 , B05B7/06 , B05B7/0815 , G01N23/2204 , H01J49/165
摘要： A nozzle for producing a liquid jet or a single-file stream of droplets of a fluid, methods using the nozzle, and an injector comprising the nozzle of the invention for providing the liquid jet or single-file stream of a fluid to a vacuum system are described.
摘要翻译： 用于产生液体射流的喷嘴或流体液滴的单一液滴流，使用喷嘴的方法，以及包括本发明的喷嘴的喷射器，用于将液体射流或单流流体提供给真空系统 被描述。
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公开(公告)号：US10724198B2
公开(公告)日：2020-07-28
申请号：US15029866
申请日：2014-10-28
发明人： Edward Kavazanjian , Nasser Hamdan
IPC分类号： E02D3/12 , C04B41/50 , C02F1/42 , C02F1/28 , C02F1/52 , C12N9/78 , B09C1/00 , C01F11/18 , C12N9/80
摘要： The present invention provides methods for mineral precipitation of porous particulate starting materials using isolated urease.
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公开(公告)号：US10391485B2
公开(公告)日：2019-08-27
申请号：US14497005
申请日：2014-09-25
发明人： Deirdre Meldrum , Roger Johnson , Iniyan Soundappa Elango , Andrew Shabilla , Hong Wang , Jakrey Myers , Laimonas Kelbauskas , Dean Smith , Pimwadee Limsirichai
摘要： A microfluidic device useable for performing live cell computed tomography imaging is fabricated with a cover portion including a first wafer with at least one metal patterned thereon, a base portion including a second wafer with at least one metal patterned thereon and negative photoresist defining recesses therein, and a diffusive bonding layer including a negative photoresist arranged to join the cover portion and the base portion. A composition useful in live cell computer topography includes a long-chain polysaccharide at a concentration of from about 0.01% to about 10.0% in cell culture medium for supporting cell life while enabling cell rotation rate to be slowed to a speed commensurate with low light level imaging.
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公开(公告)号：US10074000B2
公开(公告)日：2018-09-11
申请号：US14775447
申请日：2014-03-12
发明人： Michael N. Kozicki
IPC分类号： G06K7/10 , G06K9/00 , G06K19/06 , G06K19/08 , G06K9/20 , G06K9/62 , G06F17/30 , H04L9/32 , G02B21/06 , G02B21/36 , G02B27/28 , G09C5/00 , G06T7/00 , G06K19/077 , G06T7/12 , G06K9/46
CPC分类号： G06K7/1099 , G02B21/06 , G02B21/365 , G02B27/286 , G06F16/51 , G06F16/9554 , G06K9/00147 , G06K9/00577 , G06K9/2027 , G06K9/46 , G06K9/4671 , G06K9/6202 , G06K19/06046 , G06K19/07749 , G06K19/086 , G06T7/0012 , G06T7/12 , G06T2207/10056 , G06T2207/30024 , G09C5/00 , H04L9/3278 , H04L2209/12
摘要： The disclosure features dendritic tags, and methods and systems for fabricating and using such tags. The methods can include obtaining at least one image of a dendritic tag attached to an article, analyzing the at least one image to identify a set of features associated with the dendritic tag, and comparing the set of features to stored information to identify the article.
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