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    MEDICAL DEVICES HAVING SOFT, FLEXIBLE LUBRICIOUS COATINGS
    3.
    发明申请
    MEDICAL DEVICES HAVING SOFT, FLEXIBLE LUBRICIOUS COATINGS 有权
    具有柔软，柔性润滑涂层的医疗器械

    公开(公告)号：US20120041554A1

    公开(公告)日：2012-02-16

    申请号：US13282239

    申请日：2011-10-26

    Applicant: Can B. HU ,  Michael D. Lowery ,  Harish C. Makker

    Inventor： Can B. HU ,  Michael D. Lowery ,  Harish C. Makker

    IPC: A61F2/16 ,  A61F9/00

    CPC classification number: A61F2/1675 ,  A61L27/34 ,  C08G18/0823 ,  C08G18/833 ,  C08L39/06 ,  C09D175/04 ,  Y10T428/31536 ,  Y10T428/31551 ,  Y10T428/31663 ,  C08L5/08 ,  C08L2666/04

    Abstract: Soft, flexible highly lubricious coatings for polymeric IOL insertion cartridges that allow IOLs to be easily inserted through small bore cartridges suitable for use with small (less than 3 mm) incisions are provided. These lubricious coatings allow IOLs to be inserted into the eye of a patient without the risk of lens damage or transfer of lubricants to the lens surface during implantation. Specifically, polymeric coatings comprising a matrix polymer having an equivalent weight greater than 5000 g/eq are used to form interpenetrating networks (IPN) on the surface of hydrophobic structural polymers. The IPNs thus formed entrap highly lubricious hydrophilic compounds within the IPN using multi-functional cross linkers.

    Abstract translation: 提供用于聚合物IOL插入盒的柔软，柔性高润滑性涂层，其允许IOL容易地插入适于与小（小于3mm）切口一起使用的小孔筒。 这些光滑涂层允许IOL插入患者的眼睛，而不会在植入期间发生晶状体损伤或将润滑剂转移到镜片表面。 具体地说，使用包含当量大于5000g / eq的基质聚合物的聚合物涂层在疏水结构聚合物的表面上形成互穿网络（IPN）。 因此，IPNs使用多功能交联剂在IPN内捕获高度润滑的亲水性化合物。

    IOL INSERTION APPARATUS AND METHODS FOR MAKING AND USING SAME
    8.
    发明申请
    IOL INSERTION APPARATUS AND METHODS FOR MAKING AND USING SAME 有权
    IOL插入装置及其制造和使用方法

    公开(公告)号：US20100129523A1

    公开(公告)日：2010-05-27

    申请号：US12622554

    申请日：2009-11-20

    Applicant: Harish Makker ,  Can Hu ,  Michael D. Lowery

    Inventor： Harish Makker ,  Can Hu ,  Michael D. Lowery

    IPC: B05D3/02

    CPC classification number: A61F2/1664 ,  A61F2/167 ,  A61F2/1675 ,  A61F2/1678 ,  Y10T428/1393

    Abstract: Apparatus, and methods of making and using apparatus, for inserting intraocular lenses (IOLs) are disclosed. The apparatus includes a hollow tube having an interior wall defining a hollow space through which an intraocular lens may be passed from the open space into an eye. A lubricity enhancing component is covalently bonded to the hollow tube at the interior wall in an amount effective to facilitate the passage of the intraocular lens through the hollow space. The lubricity enhancing component includes a substituent component effective to reduce hydrolysis of said lubricity enhancing component relative to an identical lubricity enhancing component without the substituent component.

    Abstract translation: 公开了用于插入眼内透镜（IOL）的装置和制造和使用装置的方法。 该装置包括具有限定中空空间的内壁的中空管，眼内透镜可以通过该中空空间从开放空间传入眼睛。 润滑性增强组分以有效促进眼内透镜通过中空空间的量在内壁处共价结合到中空管。 润滑性增强组分包括相对于没有取代基组分的相同润滑性增强组分有效减少所述润滑性增强组分的水解的取代基组分。

    LENS SURFACE ENHANCEMENT
    9.
    发明申请
    LENS SURFACE ENHANCEMENT 审中-公开
    镜头表面增强

    公开(公告)号：US20090234450A1

    公开(公告)日：2009-09-17

    申请号：US12470894

    申请日：2009-05-22

    Applicant: Michael D. Lowery ,  Laurent Hoffmann

    Inventor： Michael D. Lowery ,  Laurent Hoffmann

    IPC: A61F2/16 ,  C23C16/00 ,  C08G77/02

    CPC classification number: A61L27/50 ,  A61F2/16 ,  A61L27/34 ,  A61L2430/16 ,  C08L71/02

    Abstract: An intraocular lens with a hydrophilic polymer coating composition and methods for using same are provided. Specifically, a composition suitable for reducing tackiness in intraocular lens is provided wherein an acrylic intraocular lens is treated by vapor deposition with an alkoxy silyl terminated polyethylene glycol polymer composition. Methods for making an intraocular lens with a hydrophilic polymer coating are also provided.

    Abstract translation: 提供具有亲水性聚合物涂层组合物的人工晶状体及其使用方法。 具体地说，提供一种适用于降低人工晶状体粘合性的组合物，其中丙烯酸类眼内透镜通过气相沉积用烷氧基甲硅烷基封端的聚乙二醇聚合物组合物进行处理。 还提供了制备具有亲水性聚合物涂层的眼内透镜的方法。

    Soft Silicone Materials for Ophthalmic Applications
    10.
    发明申请
    Soft Silicone Materials for Ophthalmic Applications 有权
    软硅胶材料用于眼科应用

    公开(公告)号：US20090164009A1

    公开(公告)日：2009-06-25

    申请号：US12205703

    申请日：2008-09-05

    Applicant: Can Hu ,  Derek D. Pham ,  Michael D. Lowery

    Inventor： Can Hu ,  Derek D. Pham ,  Michael D. Lowery

    IPC: A61F2/16 ,  C08G77/04 ,  G02B3/12 ,  G02C7/04 ,  B29D11/00

    CPC classification number: A61F2/16 ,  A61F2002/16905 ,  C08G77/20 ,  G02B1/043 ,  C08L83/04

    Abstract: Described herein are silicone fluids and silicone materials that posses high glass transition temperatures (Tgs) when compared to conventional silicone materials. In one embodiment, an increased Tg allows the formation of objects and materials by cryogenic lathing. The fluids and materials can be formed by curing silicone fluid with a cross-linker mixture comprising a cross-linker and a monofunctional hydride compound. Upon formation, the silicone materials can be extracted over long periods of time without loss of optical quality. The silicone materials can be sufficiently soft allowing folding and insertion through small incisions in the eye. Additionally, methods of forming optical silicone materials, lenses and silicone materials in general are also disclosed. In one embodiment, the method of forming a silicone based lens using cryogenic lathing techniques is described.

    Abstract translation: 这里描述的是与常规硅氧烷材料相比具有高玻璃化转变温度（Tg）的有机硅流体和硅氧烷材料。 在一个实施例中，增加的Tg允许通过低温车辙形成物体和材料。 流体和材料可以通过用包含交联剂和单官能氢化物化合物的交联剂混合物固化硅氧烷流体来形成。 在形成时，可以长时间地提取硅酮材料而不损失光学质量。 硅胶材料可以足够柔软，允许通过眼睛中的小切口进行折叠和插入。 此外，还公开了形成光学硅氧烷材料，透镜和硅酮材料的方法。 在一个实施例中，描述了使用低温车床技术形成硅氧烷基透镜的方法。

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