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1.发明申请Genetic elements, proteins, and associated methods including application of additional genetic information to gram (+) thermoacidophiles 审中-公开遗传因素，蛋白质和相关方法，包括向克（+）热嗜酸粒细胞应用额外的遗传信息公开(公告)号：US20110275135A1
公开(公告)日：2011-11-10
申请号：US12800045
申请日：2010-05-05
申请人： Brady D. Lee , Deborah T. Newby , Jeffrey A. Lacey , David N. Thompson , Vicki S. Thompson , William A. Apel , Francisco F. Roberto , David W. Reed
发明人： Brady D. Lee , Deborah T. Newby , Jeffrey A. Lacey , David N. Thompson , Vicki S. Thompson , William A. Apel , Francisco F. Roberto , David W. Reed
IPC分类号： C12N9/02 , C12N9/14 , C12N9/00 , C12N9/90 , C07K14/195 , C12N9/16 , C12N9/10 , C12N9/12 , C07H21/00 , C12N9/52
CPC分类号： C12N15/74 , C07K14/195 , C12N9/00 , C12N9/1007 , C12N9/52 , C12N15/87 , C12Y201/01072
摘要： Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods for modulating or altering recombination inside or outside of a cell using isolated and/or purified polypeptides and/or nucleic acid sequences from Alicyclobacillus acidocaldarius.
摘要翻译： 提供了分离和/或纯化的多肽和编码来自酸热环酸杆菌的多肽的核酸序列。 进一步提供的是使用分离和/或纯化的多肽和/或酸碱热杆菌的核酸序列调节或改变细胞内部或外部的重组的方法。
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2.发明申请GENETIC ELEMENTS, PROTEINS, AND ASSOCIATED METHODS INCLUDING APPLICATION OF ADDIITNAL GENETIC INFORMATION TO GRAM (+) THERMOACIDOPHILES 有权遗传元素，蛋白质和相关方法，包括将添加剂基因信息应用于GRAM（+）热保护素公开(公告)号：US20130029400A1
公开(公告)日：2013-01-31
申请号：US13604979
申请日：2012-09-06
申请人： Brady D. Lee , Deborah T. Newby , Jeffrey A. Lacey , David N. Thompson , Vicki S. Thompson , William A. Apel , Francisco F. Roberto , David W. Reed
发明人： Brady D. Lee , Deborah T. Newby , Jeffrey A. Lacey , David N. Thompson , Vicki S. Thompson , William A. Apel , Francisco F. Roberto , David W. Reed
IPC分类号： C12N15/52 , C12N9/14 , C12N9/00 , C12N9/52 , C12N9/16 , C07K14/195 , C12N9/12 , C12N9/90 , C12N9/02 , C12N9/22 , C12N15/31 , C12N15/63 , C12N9/10
CPC分类号： C12N15/74 , C07K14/195 , C12N9/00 , C12N9/1007 , C12N9/52 , C12N15/87 , C12Y201/01072
摘要： Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods for modulating or altering recombination inside or outside of a cell using isolated and/or purified polypeptides and/or nucleic acid sequences from Alicyclobacillus acidocaldarius.
摘要翻译： 提供了分离和/或纯化的多肽和编码来自酸热环酸杆菌的多肽的核酸序列。 进一步提供的是使用分离和/或纯化的多肽和/或酸碱热杆菌的核酸序列调节或改变细胞内部或外部的重组的方法。
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3.发明申请公开(公告)号：US20090269827A1
公开(公告)日：2009-10-29
申请号：US12380551
申请日：2009-02-26
申请人： Vicki S. Thompson , William A. Apel , David W. Reed , Brady D. Lee , David N. Thompson , Francisco F. Roberto , Jeffrey A. Lacey
发明人： Vicki S. Thompson , William A. Apel , David W. Reed , Brady D. Lee , David N. Thompson , Francisco F. Roberto , Jeffrey A. Lacey
IPC分类号： C12N9/02 , C12N9/00 , C12N9/10 , C12N9/12 , C12N9/88 , C12N9/90 , C12N5/06 , C12N15/00 , C12N15/11
CPC分类号： C12N9/88 , C12N9/00 , C12N9/1029 , C12N15/74 , C12N15/75 , C12Y203/01009 , C12Y402/01055
摘要： Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods for modulating or altering metabolism in a cell using isolated and/or purified polypeptides and nucleic acid sequences from Alicyclobacillus acidocaldarius.
摘要翻译： 提供了分离和/或纯化的多肽和编码来自酸热环酸杆菌的多肽的核酸序列。 还提供了使用分离和/或纯化的多肽和酸性脂多酸杆菌的核酸序列调节或改变细胞代谢的方法。
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4.发明授权公开(公告)号：US08728803B2
公开(公告)日：2014-05-20
申请号：US12380551
申请日：2009-02-26
申请人： Vicki S. Thompson , William A. Apel , David W. Reed , Brady D. Lee , David N. Thompson , Francisco F. Roberto , Jeffrey A. Lacey
发明人： Vicki S. Thompson , William A. Apel , David W. Reed , Brady D. Lee , David N. Thompson , Francisco F. Roberto , Jeffrey A. Lacey
CPC分类号： C12N9/88 , C12N9/00 , C12N9/1029 , C12N15/74 , C12N15/75 , C12Y203/01009 , C12Y402/01055
摘要： Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods for modulating or altering metabolism in a cell using isolated and/or purified polypeptides and nucleic acid sequences from Alicyclobacillus acidocaldarius.
摘要翻译： 提供了分离和/或纯化的多肽和编码来自酸热环酸杆菌的多肽的核酸序列。 还提供了使用分离和/或纯化的多肽和酸性脂多酸杆菌的核酸序列调节或改变细胞代谢的方法。
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5.发明授权Transcriptional control in Alicyclobacillus acidocaldarius and associated genes, proteins, and methods 有权转录酸控制在酸性脂环酸杆菌和相关基因，蛋白质和方法公开(公告)号：US08716011B2
公开(公告)日：2014-05-06
申请号：US12380008
申请日：2009-02-20
申请人： Brady D. Lee , David N. Thompson , William A. Apel , Vicki S. Thompson , David W. Reed , Jeffrey A. Lacey
发明人： Brady D. Lee , David N. Thompson , William A. Apel , Vicki S. Thompson , David W. Reed , Jeffrey A. Lacey
CPC分类号： C12N15/635 , C07K14/195 , C12N15/74
摘要： Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods of modulating transcription or transcription or transcriptional control using isolated and/or purified polypeptides and nucleic acid sequences from Alicyclobacillus acidocaldarius.
摘要翻译： 提供了分离和/或纯化的多肽和编码来自酸热环酸杆菌的多肽的核酸序列。 进一步提供的是使用分离的和/或纯化的多肽和来自酸热环酸杆菌的核酸序列调节转录或转录或转录控制的方法。
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6.发明授权公开(公告)号：US08569030B2
公开(公告)日：2013-10-29
申请号：US13604979
申请日：2012-09-06
申请人： Brady D. Lee , Deborah T. Newby , Jeffrey A. Lacey , David N. Thompson , Vicki S. Thompson , William A. Apel , Francisco F. Roberto , David W. Reed
发明人： Brady D. Lee , Deborah T. Newby , Jeffrey A. Lacey , David N. Thompson , Vicki S. Thompson , William A. Apel , Francisco F. Roberto , David W. Reed
CPC分类号： C12N15/74 , C07K14/195 , C12N9/00 , C12N9/1007 , C12N9/52 , C12N15/87 , C12Y201/01072
摘要： Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods for modulating or altering recombination inside or outside of a cell using isolated and/or purified polypeptides and/or nucleic acid sequences from Alicyclobacillus acidocaldarius.
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7.发明申请Transcriptional control in alicyclobacillus acidocaldarius and associated genes, proteins, and methods 有权脂肪酸杆菌中的转录控制和相关基因，蛋白质和方法公开(公告)号：US20090215168A1
公开(公告)日：2009-08-27
申请号：US12380008
申请日：2009-02-20
申请人： Brady D. Lee , David N. Thompson , William A. Apel , Vicki S. Thompson , David W. Reed , Jeffrey A. Lacey
发明人： Brady D. Lee , David N. Thompson , William A. Apel , Vicki S. Thompson , David W. Reed , Jeffrey A. Lacey
CPC分类号： C12N15/635 , C07K14/195 , C12N15/74
摘要： Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods of modulating transcription or transcription or transcriptional control using isolated and/or purified polypeptides and nucleic acid sequences from Alicyclobacillus acidocaldarius.
摘要翻译： 提供了分离和/或纯化的多肽和编码来自酸热环酸杆菌的多肽的核酸序列。 进一步提供的是使用分离的和/或纯化的多肽和来自酸热环酸杆菌的核酸序列调节转录或转录或转录控制的方法。
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8.发明申请ALTERATION AND MODULATION OF PROTEIN ACTIVITY BY VARYING POST-TRANSLATIONAL MODIFICATION 有权通过改变后期修改来改变和调节蛋白质活性公开(公告)号：US20150225706A1
公开(公告)日：2015-08-13
申请号：US14632770
申请日：2015-02-26
IPC分类号： C12N9/24
CPC分类号： C12N9/2402 , C12N9/1048 , C12N9/1051 , C12N9/1288 , C12N9/2437 , C12N9/2477 , C12N9/2482 , C12P21/00 , C12P21/005 , C12Y302/01004 , C12Y302/01008 , Y02P20/52
摘要： Embodiments of the invention include methods of altering the enzymatic activity or solubility of an extremophilic enzyme or post-translationally modifying a protein of interest via using isolated or partially purified glycosyltransferases and/or post-translational modification proteins, extracts of cells comprising glycosyltransferases and/or post-translational modification proteins, and/or in cells comprising one or more glycosyltransferases and/or post-translational modification proteins.
摘要翻译： 本发明的实施方案包括通过使用分离或部分纯化的糖基转移酶和/或翻译后修饰蛋白来改变极端酶的酶活性或溶解度或翻译后修饰目的蛋白质的方法，包含糖基转移酶和/或 和/或包含一个或多个糖基转移酶和/或翻译后修饰蛋白的细胞。
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9.发明授权Thermophilic and thermoacidophilic biopolymer-degrading genes and enzymes from alicyclobacillus acidocaldarius and related organisms, methods 有权嗜热和热嗜酸性生物聚合物降解基因和酸性脂肪酸杆菌和相关生物的酶，方法公开(公告)号：US08497110B2
公开(公告)日：2013-07-30
申请号：US12927504
申请日：2010-11-15
申请人： David N. Thompson , William A. Apel , Vicki S. Thompson , David W. Reed , Jeffrey A. Lacey , Emily D. Henriksen
发明人： David N. Thompson , William A. Apel , Vicki S. Thompson , David W. Reed , Jeffrey A. Lacey , Emily D. Henriksen
IPC分类号： C12N9/42 , C12N9/24 , C12N9/14 , C12N15/00 , C12P21/06 , C12P19/34 , C12P19/00 , C07H21/04 , C07K1/00
CPC分类号： C12P19/14 , C12N9/1051 , C12N9/16 , C12N9/18 , C12N9/2402 , C12N9/2408 , C12N9/2428 , C12N9/2434 , C12N9/2437 , C12N9/2445 , C12N9/2465 , C12N9/2471 , C12N9/248 , C12N9/2482 , C12N9/2494 , C12N9/80 , C12N9/88 , C12N15/52 , C12P19/00 , C12P19/02 , C12Y204/0102 , C12Y301/01001 , C12Y301/01006 , C12Y301/01073 , C12Y301/02004 , C12Y302/01008 , C12Y302/01015 , C12Y302/0102 , C12Y302/01021 , C12Y302/01022 , C12Y302/01037 , C12Y302/01055 , C12Y302/01078 , C12Y302/01091 , C12Y302/01131 , C12Y302/01133 , C12Y302/01139 , C12Y305/01 , C12Y402/01007 , C12Y402/01008
摘要： Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods of at least partially degrading, cleaving, or removing polysaccharides, lignocellulose, cellulose, hemicellulose, lignin, starch, chitin, polyhydroxybutyrate, heteroxylans, glycosides, xylan-, glucan-, galactan-, or mannan-decorating groups using isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius.
摘要翻译： 提供了分离和/或纯化的多肽和编码来自酸热环酸杆菌的多肽的核酸序列。 还提供了使用分离的至少部分降解，切割或除去多糖，木质纤维素，纤维素，半纤维素，木质素，淀粉，几丁质，聚羟基丁酸酯，异木聚糖，糖苷，木聚糖，葡聚糖，半乳聚糖或甘露聚糖装饰基团的方法 和/或编码来自酸性脂多酸杆菌的多肽的纯化多肽和核酸序列。
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10.发明授权Thermal and acid tolerant beta xylosidases, arabinofuranosidases, genes encoding, related organisms, and methods 有权热和酸耐受性β木糖苷酶，阿拉伯呋喃糖苷酶，编码相关生物的基因和方法公开(公告)号：US08431379B2
公开(公告)日：2013-04-30
申请号：US12802911
申请日：2010-06-15
申请人： David N. Thompson , Vicki S. Thompson , Kastli D. Schaller , William A. Apel , David W. Reed , Jeffrey A. Lacey
发明人： David N. Thompson , Vicki S. Thompson , Kastli D. Schaller , William A. Apel , David W. Reed , Jeffrey A. Lacey
IPC分类号： C12N9/24
CPC分类号： C12Y302/01037 , C12N9/2402 , C12N9/248 , C12N9/2482 , C12Y302/01055 , D21C5/005 , D21C11/0007
摘要： Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius and variations thereof are provided. Further provided are methods of at least partially degrading xylotriose, xylobiose, and/or arabinofuranose-substituted xylan using isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius and variations thereof.
摘要翻译： 提供了分离和/或纯化的多肽和编码来自酸热环酸杆菌的多肽的核酸序列及其变体。 还提供了使用分离和/或纯化的多肽和编码来自酸碱热杆菌的多肽的核酸序列及其变体来至少部分降解木三糖，木二糖和/或阿拉伯呋喃糖取代的木聚糖的方法。
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