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    Microfluidic controller and detector system with self-calibration
    2.
    发明授权
    Microfluidic controller and detector system with self-calibration 有权
    微流控制器和检测器系统具有自校准功能

    公开(公告)号：US06498497B1

    公开(公告)日：2002-12-24

    申请号：US09374878

    申请日：1999-08-13

    申请人： Calvin Y. H. Chow ,  Morten J. Jensen ,  Colin B. Kennedy ,  Michael M. Lacy ,  Robert E. Nagle

    发明人： Calvin Y. H. Chow ,  Morten J. Jensen ,  Colin B. Kennedy ,  Michael M. Lacy ,  Robert E. Nagle

    IPC分类号： G01R3500

    CPC分类号： G01N27/44721 ,  B01L3/5027 ,  B01L9/527 ,  B01L2200/027 ,  B01L2200/148 ,  B01L2400/0415 ,  G01N27/44791

    摘要： A microfluidic controller and detector system and method for performing screening assays are disclosed. The microfluidic controller and detector system comprises a fluidic chip that includes at least two intersecting channels and a detection zone, a fluid direction system comprising an electrical interface configured for electrical contact with the at least two intersecting channels, an optics block having an objective lens disposed adjacent the detection zone, and a control system coupled to the optics block and adapted to receive and analyze data from the optics block. The electrical interface generally includes electrodes configured for electrical contact with the intersecting channels and coupled to electrode channels for supplying electrical input to the electrodes. A reference channel is optionally provided to calibrate the electrode channels.

    摘要翻译： 公开了用于进行筛选测定的微流控制器和检测器系统和方法。 微流控制器和检测器系统包括流体芯片，其包括至少两个相交通道和检测区域，流体方向系统，包括被配置为与所述至少两个相交通道电接触的电接口， 邻近所述检测区域，以及控制系统，其耦合到所述光学块并适于从所述光学块接收和分析数据。 电接口通常包括被配置为与交叉通道电接触并且耦合到用于向电极提供电输入的电极通道的电极。 可选地提供参考通道以校准电极通道。

    Fluidic devices having incorporated electrodes
    10.
    发明授权
    Fluidic devices having incorporated electrodes 有权
    具有并入电极的流体装置

    公开(公告)号：US08367021B2

    公开(公告)日：2013-02-05

    申请号：US13030379

    申请日：2011-02-18

    申请人： Colin B. Kennedy ,  Josh Molho ,  Alexander V. Dukhovny

    发明人： Colin B. Kennedy ,  Josh Molho ,  Alexander V. Dukhovny

    IPC分类号： F15D1/00 ,  B23P11/00

    CPC分类号： G01N27/44743 ,  B01L3/5027 ,  B01L3/502715 ,  B01L3/502753 ,  B01L9/527 ,  B01L2200/027 ,  B01L2200/0636 ,  B01L2300/0816 ,  B01L2300/0887 ,  B01L2300/1894 ,  B01L2400/0421 ,  B01L2400/0481 ,  G01N27/44717 ,  G01N27/44791 ,  G01N30/84 ,  G01N33/5438 ,  Y10T29/49826 ,  Y10T137/8158 ,  Y10T137/8376

    摘要： The invention provides fluidic devices having incorporated electrodes. One device comprises a card and a caddy. The card includes a channel disposed within the card, first and second vias in fluid communication with the channel through an upper surface of the card, and first and second electrodes disposed on the upper surface of the card. The first via and first electrode are positioned adjacent to a first end of the channel, and the second via and second electrode are positioned adjacent to a second end of the channel. The caddy comprises first and second reservoirs. The caddy is attached to the card such that the first reservoir is positioned over the first via and a portion of the first electrode, and the second reservoir is positioned over the second via and a portion of the second electrode. A portion of each of the electrodes is accessible for dry electrical contact.

    摘要翻译： 本发明提供具有并入电极的流体装置。 一个设备包括一个卡和一个球童。 卡片包括布置在卡内的通道，通过卡的上表面与通道流体连通的第一和第二通孔以及设置在卡的上表面上的第一和第二电极。 第一通孔和第一电极定位成与通道的第一端相邻，并且第二通孔和第二电极定位成与通道的第二端相邻。 球童包括第一和第二储层。 所述卡盘连接到所述卡片上，使得所述第一储存器位于所述第一通孔上方，并且所述第一电极的一部分位于所述第二通孔和所述第二电极的一部分上。 每个电极的一部分可用于干电接触。