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公开(公告)号：US20090187201A1
公开(公告)日：2009-07-23
申请号：US12351665
申请日：2009-01-09
IPC分类号： A61B17/08
CPC分类号： A61B17/12099 , A61B5/036 , A61B5/073 , A61B5/14539 , A61B17/12022 , A61B17/12136 , A61B17/12172 , A61B17/12177 , A61B17/1219 , A61B2017/00818 , A61B2017/00867 , A61B2017/00893 , A61B2017/1205 , A61B2017/12054 , A61B2017/12086 , A61F5/003 , A61F5/0036 , A61F5/0079
摘要： Methods, devices and systems facilitate gastric retention of a variety of therapeutic devices. devices generally include a support portion for preventing the device from passing through the pyloric valve or esophagus wherein a retaining member may optionally be included on the distal end of the positioning member for further maintaining a position of the device in the stomach. Some embodiments are deliverable into the stomach through the esophagus, either by swallowing or through a delivery tube or catheter. Some embodiments are fully reversible. Some embodiments self-expand within the stomach, while others are inflated or otherwise expanded.
摘要翻译： 方法，装置和系统促进各种治疗装置的胃滞留。 装置通常包括用于防止装置通过幽门阀或食道的支撑部分，其中保持构件可以可选地包括在定位构件的远端上，以进一步保持装置在胃中的位置。 一些实施例可通过吞咽或通过输送管或导管通过食道输送到胃中。 一些实施例是完全可逆的。 一些实施例在胃内自扩张，而另一些实施例被膨胀或以其他方式扩张。
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公开(公告)号：US20090187200A1
公开(公告)日：2009-07-23
申请号：US12351644
申请日：2009-01-09
IPC分类号： A61B17/08
CPC分类号： A61B17/12099 , A61B5/036 , A61B5/073 , A61B5/14539 , A61B17/12022 , A61B17/12136 , A61B17/12172 , A61B17/12177 , A61B17/1219 , A61B2017/00818 , A61B2017/00867 , A61B2017/00893 , A61B2017/1205 , A61B2017/12054 , A61B2017/12086 , A61F5/003 , A61F5/0036 , A61F5/0079
摘要： Methods, devices and systems facilitate gastric retention of a variety of therapeutic devices. devices generally include a support portion for preventing the device from passing through the pyloric valve or esophagus wherein a retaining member may optionally be included on the distal end of the positioning member for further maintaining a position of the device in the stomach. Some embodiments are deliverable into the stomach through the esophagus, either by swallowing or through a delivery tube or catheter. Some embodiments are fully reversible. Some embodiments self-expand within the stomach, while others are inflated or otherwise expanded.
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3.发明申请公开(公告)号：US20120197245A1
公开(公告)日：2012-08-02
申请号：US13361779
申请日：2012-01-30
申请人： Daniel Rogers BURNETT , Brian Michael NEIL , William Walter MALECKI , Kathleen Marie KOCH , Gregory Jin-keng LEE
发明人： Daniel Rogers BURNETT , Brian Michael NEIL , William Walter MALECKI , Kathleen Marie KOCH , Gregory Jin-keng LEE
CPC分类号： A61F7/123 , A61B5/01 , A61B5/4836 , A61B5/6853 , A61B17/12022 , A61B18/02 , A61B18/0218 , A61B18/04 , A61B2017/00539 , A61B2018/00011 , A61B2018/00041 , A61B2018/0022 , A61B2018/00488 , A61B2018/00553 , A61B2018/00559 , A61B2018/00577 , A61B2018/00791 , A61B2018/00863 , A61B2018/00982 , A61B2018/0212 , A61B2018/0262 , A61B2018/046
摘要： Methods and apparatus for the treatment of a body cavity or lumen are described where a heated fluid and/or gas may be introduced through a catheter and into treatment area within the body contained between one or more inflatable/expandable members. The catheter may also have optional pressure and temperature sensing elements which may allow for control of the pressure and temperature within the treatment zone and also prevent the pressure from exceeding a pressure of the inflatable/expandable members to thereby contain the treatment area between these inflatable/expandable members. Optionally, a chilled, room temperature, or warmed fluid such as water may then be used to rapidly terminate the treatment session.
摘要翻译： 描述了用于治疗体腔或内腔的方法和装置，其中加热的流体和/或气体可以通过导管引入到包含在一个或多个可充气/可膨胀构件之间的体内的治疗区域中。 导管还可以具有可选的压力和温度感测元件，其可以允许控制处理区域内的压力和温度，并且还防止压力超过可充气/可膨胀构件的压力，由此容纳这些可充气/ 可扩展成员。 任选地，可以使用冷冻的室温或诸如水的温热流体来快速终止治疗会话。
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公开(公告)号：US20110295168A1
公开(公告)日：2011-12-01
申请号：US13019037
申请日：2011-02-01
IPC分类号： A61H9/00
CPC分类号： A61H9/005 , A61H2201/1238 , A61H2201/165 , A61H2205/10 , A61H2209/00
摘要： Devices that employ external compression stocking-type garments in the treatment of edema, chronic wounds, deep venous thrombosis prevention or claudication all share a number of significant limitations. These include the frequent need for custom fitting to assure an appropriate fit, vigilant maintenance to assure a continued “good fit,” limited compliance with proper use by patients and difficulty of application. There is a large body of evidence demonstrating that patients often decline to wear the compressive stockings as prescribed or in the form that would be most beneficial because they find these devices to be difficult to put on and take off. Building on the limitations of existing therapies, and distilled lessons learned from the field of prosthetics and wound healing, the present invention employs vacuum-assisted negative pressure to provide compression and help pump fluid from the tissues of affected limbs. The device is embodied in the form of a flexible stocking-like garment that will utilize a pumping mechanism to generate negative pressure around the limb and thus create vacuum compression that will mobilize fluid in a limb and increase venous return to the heart. Through the use of a circumferential wrap, the present invention provides a major advance in both the distribution of vacuum and the securing of the device over the limb.
摘要翻译： 使用外部压缩放养型衣服治疗水肿，慢性伤口，深静脉血栓预防或跛行的装置都具有一些显着的局限性。 这些包括经常需要定制配件，以确保适当的配合，警惕的维护，以确保持续的“良好配合”，限制患者适当使用的合规和应用难度。 有大量证据表明，患者经常拒绝按规定佩戴压缩丝袜，或以最有利的形式，因为他们发现这些装置难以穿上和起飞。 基于现有疗法的局限性，以及从假肢和伤口愈合领域获得的经验教训，本发明采用真空辅助负压来提供压迫并帮助受影响肢体的组织泵送液体。 该装置体现为柔性袜子样衣服的形式，其将利用泵送机构在肢体周围产生负压，并因此产生将在肢体中调动流体并增加静脉回流到心脏的真空压缩。 通过使用圆周包裹体，本发明提供了真空分配和将装置固定在肢体上的重大进步。
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5.发明申请METHOD AND APPARATUS FOR AUTOMATED ACTIVE STERILIZATION OF FULLY IMPLANTED DEVICES 有权用于自动主动灭菌完全植入装置的方法和装置公开(公告)号：US20100256607A1
公开(公告)日：2010-10-07
申请号：US12702977
申请日：2010-02-09
CPC分类号： A61M25/0017 , A61F2/042 , A61F2/82 , A61L2/02 , A61L2/025 , A61L2/08 , A61L2/10 , A61L2/12 , A61L2/18 , A61M5/142 , A61M2025/0056 , A61M2205/0205 , A61M2205/051 , A61M2205/054 , A61M2205/058
摘要： The current invention provides this advance in infection control via its unique application of active sterilization to a catheter or implant. While most catheters, and many implants, are passive devices, the current invention will provide an active component as a integral part of the implanted catheter or device to continuously or intermittently sterilize the exposed surfaces/areas of the device. This active sterilization may be accomplished by a variety of mechanisms, including, application of heat, RF, microwave, ultrasound, ultraviolet radiation or other energy capable of sterilizing the device or dislodging any problematic Biofilm that may form. The active sterilization may also employ the pumping of a sterilizing chemical from an attached drug reservoir, the use of electricity or freezing temperatures or any other mechanism for either inhibiting, killing or dislodging any infectious material in contact with the implant. One major advantage of this design is that through the use of a small, battery powered or inductively powered sterilization element, the implanted catheter or device can be effectively sterilized without requiring the standard removal surgery, waiting period, then replacement of the infected device. This is expected to translate into greatly improved outcomes (particularly for devices where infection may be catastrophic, ie a prosthetic knee or hip), greatly improved costs, and greatly improved longevity of susceptible devices (ie IV ports, etc.).
摘要翻译： 本发明通过其对导管或植入物的主动消毒的独特应用来提供感染控制方面的进步。 虽然大多数导管和许多植入物是无源器件，但是本发明将提供作为植入的导管或装置的组成部分的有源部件，以连续或间歇地对设备的暴露表面/区域进行灭菌。 这种有效的灭菌可以通过各种机制来实现，包括施加热，RF，微波，超声波，紫外线辐射或其他能够对装置进行灭菌或消除可能形成的任何有问题的生物膜的能量。 活性灭菌还可以使用从连接的药物储存器泵送灭菌化学品，使用电力或冷冻温度或任何其它机制来抑制，杀死或移除与植入物接触的任何传染性材料。 该设计的一个主要优点是通过使用小型的电池供电或感应供电的消毒元件，可以有效地对植入的导管或装置进行灭菌，而无需进行标准去除手术，等待期，然后更换被感染的装置。 预期这将转化为大大改善的结果（特别是对于感染可能是灾难性的，即假肢膝盖或髋关节的设备），大大提高了成本，并大大改善了敏感设备（即IV端口等）的寿命。
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公开(公告)号：US20100204538A1
公开(公告)日：2010-08-12
申请号：US12509304
申请日：2009-07-24
CPC分类号： A61N2/006 , A61N1/0456 , A61N1/0476 , A61N1/0551 , A61N1/36007 , A61N1/36017 , A61N1/36021 , A61N1/36057 , A61N1/3787 , A61N2/004 , A61N2/02
摘要： An energy emitting, apparatus for providing a medical therapy includes one or more energy generators, a logic controller electrically connected to the one or more energy generators, and one or more sensors that are connected to the logic controller for detecting electric conduction in a target nerve. The energy generators produce energy focused on the target nerve upon receiving a signal from the logic controller, and the energy is varied by the logic controller according to an input provided by the one or more sensors. The energy emitting apparatus includes one or more conductive coils that produce a magnetic field focused on the target nerve upon receiving an electric current from the logic controller based on input provided by the sensors. The sensor may also include a microneedle array to detect electrical conduction or an energy emitting apparatus may include a microneedle array to produce or deliver energy, an electrical or magnetic stimulus or field.
摘要翻译： 用于提供医疗治疗的能量发射装置包括一个或多个能量发生器，电连接到一个或多个能量发生器的逻辑控制器，以及连接到逻辑控制器的一个或多个传感器，用于检测目标神经中的电传导 。 能量发生器在从逻辑控制器接收到信号时产生集中在目标神经上的能量，并且根据由一个或多个传感器提供的输入由逻辑控制器改变能量。 能量发射装置包括一个或多个导电线圈，其基于由传感器提供的输入从逻辑控制器接收电流而产生聚焦在目标神经上的磁场。 传感器还可以包括用于检测电传导的微针阵列，或者能量发射装置可以包括微针阵列以产生或递送能量，电或磁刺激或场。
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公开(公告)号：US20100222629A1
公开(公告)日：2010-09-02
申请号：US12606941
申请日：2009-10-27
IPC分类号： A61N2/02
摘要： Energy emitting systems are provided which include an adjustable conductive coil configured to generate a magnetic or electromagnetic field focused on a target nerve. The coil includes a central aperture which may be adjustable between a first configuration and a second configuration having a radius greater than the radius of the first configuration. The adjustable or movable nature of the coil allows the conductive coil to conform to, accommodate, or be positioned on a particular anatomical structure of a patient to position the coil in proximity to the underlying target nerve. In certain embodiments, methods of magnetic induction therapy are provided which include positioning a conductive coil relative to a portion of a patient's body by adjusting the central aperture of the coil such that the coil may conform to, accommodate or be positioned on the portion of the patient's body in proximity to the underlying target nerve.
摘要翻译： 提供能量发射系统，其包括被配置为产生聚焦在目标神经上的磁场或电磁场的可调导电线圈。 线圈包括可以在第一配置和第二配置之间可调节的中心孔，其具有大于第一配置的半径的半径。 线圈的可调节或可移动的性质允许导电线圈符合，适应或定位在患者的特定解剖结构上，以将线圈定位在接近下面的目标神经。 在某些实施例中，提供了磁感应治疗的方法，其包括通过调节线圈的中心孔来相对于患者身体的一部分定位导电线圈，使得线圈可以符合，适应或定位在患者身体的一部分上 患者的身体靠近潜在的目标神经。
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公开(公告)号：US20100160712A1
公开(公告)日：2010-06-24
申请号：US12509345
申请日：2009-07-24
CPC分类号： A61N2/006 , A61N1/0456 , A61N1/0476 , A61N1/0551 , A61N1/36007 , A61N1/36017 , A61N1/36021 , A61N1/36057 , A61N1/3787 , A61N2/004 , A61N2/02
摘要： An energy emitting apparatus for providing a medical therapy includes one or more energy generators, a logic controller electrically connected to the one or more energy generators, and one or more sensors that are connected to the logic controller for detecting electric conduction in a target nerve. The energy generators produce energy focused on the target nerve upon receiving a signal from the logic controller, and the energy is varied by the logic controller according to an input provided by the one or more sensors. The energy emitting apparatus includes one or more conductive coils that produce a magnetic field focused on the target nerve upon receiving an electric current from the logic controller based on input provided by the sensors. The sensor may also include a microneedle array to detect electrical conduction or an energy emitting apparatus may include a microneedle array to produce or deliver energy, an electrical or magnetic stimulus or field.
摘要翻译： 用于提供医疗治疗的能量发射装置包括一个或多个能量发生器，电连接到一个或多个能量发生器的逻辑控制器，以及连接到逻辑控制器的一个或多个传感器，用于检测目标神经中的电传导。 能量发生器在从逻辑控制器接收到信号时产生集中在目标神经上的能量，并且根据由一个或多个传感器提供的输入由逻辑控制器改变能量。 能量发射装置包括一个或多个导电线圈，其基于由传感器提供的输入从逻辑控制器接收电流而产生聚焦在目标神经上的磁场。 传感器还可以包括用于检测电传导的微针阵列，或者能量发射装置可以包括微针阵列以产生或递送能量，电或磁刺激或场。
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公开(公告)号：US20090182358A1
公开(公告)日：2009-07-16
申请号：US12352508
申请日：2009-01-12
IPC分类号： A61B17/08
CPC分类号： A61F5/0079 , A61B5/065 , A61B17/12022 , A61B17/1204 , A61B17/12099 , A61B17/12136 , A61B17/12159 , A61B17/12163 , A61B17/12172 , A61B17/1219 , A61B2017/00119 , A61B2017/00221 , A61B2017/22069 , A61M5/14276 , A61M5/1723 , A61M31/002
摘要： The present invention relates to a device for intermittently obstructing a bodily opening, such as a gastric opening, and includes a proximal member connected to a distal member by a tether. The proximal member includes an apron member surrounding a first occluding member, which is formable from an elongated and narrower configuration to a contracted or expanded but wider configuration. When employed in the stomach, the device of the present invention is arranged transluminally, with the distal member disposed in the duodenum and the proximal member disposed against the pyloric valve, intermittently occluding the pyloric valve and preventing or delaying the flow of gastric contents through the pyloric valve. In certain embodiments, a reservoir may be included for releasing a substance of interest, for example for releasing insulin from a reservoir disposed in the distal member. Sensors, actuators, and data transmission devices may also be included.
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公开(公告)号：US20120165641A1
公开(公告)日：2012-06-28
申请号：US13306335
申请日：2011-11-29
CPC分类号： A61B5/14532 , A61B5/1455 , A61B5/1459 , A61B5/1473 , A61B5/14865 , A61B5/4839
摘要： A device may be implanted subcutaneously with an attached catheter inserted within, e.g., the peritoneal cavity of a subject. The catheter and/or device may also be inserted into another space, e.g., subcutaneous, vascular, peritoneal, cerebrospinal, pleural spaces, etc. The peritoneal fluid which normally collects and/or flows through the peritoneal cavity may be detected by the catheter and analyzed via the device to detect the concentration of glucose within the fluid.
摘要翻译： 皮下可以将装置植入插入在受试者的例如腹膜腔内的附接的导管。 导管和/或装置也可插入另一空间，例如皮下，血管，腹膜，脑脊液，胸膜腔等。通常通过腹膜腔收集和/或流经的腹膜液可通过导管和 通过装置分析以检测流体内葡萄糖的浓度。
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