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19 条记录 (耗时 0.082 秒)

    Novel human genes and methods of use thereof
    5.
    发明申请
    Novel human genes and methods of use thereof 审中-公开
    新型人类基因及其使用方法

    公开(公告)号：US20050214893A1

    公开(公告)日：2005-09-29

    申请号：US10968812

    申请日：2004-10-19

    申请人： Rachel Meyers ,  Rory Curtis ,  Maria Glucksmann ,  Rajasekhar Bandaru ,  Rosana Kapeller-Libermann

    发明人： Rachel Meyers ,  Rory Curtis ,  Maria Glucksmann ,  Rajasekhar Bandaru ,  Rosana Kapeller-Libermann

    IPC分类号： A61K38/00 ,  C07K14/47 ,  C07K14/705 ,  C12N9/02 ,  C12N9/10 ,  C12N9/48 ,  C12N9/90 ,  C12Q1/26 ,  G01N33/574

    CPC分类号： C12N9/0004 ,  A61K38/00 ,  C07K14/47 ,  C07K14/4702 ,  C07K14/705 ,  C12N9/1048 ,  C12N9/48 ,  C12N9/90 ,  G01N33/57411 ,  G01N2500/04

    摘要： The invention provides isolated nucleic acids molecules, designated 47476, 67210, 49875,46842,33201, 83378,84233,64708, 85041,84234,21617, 55562,23566,33489, and 57779 nucleic acid molecules, which encode novel human genes. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 47476, 67210, 49875, 46842, 33201, 83378, 84233, 64708, 85041, 84234, 21617, 55562, 23566, 33489, or 57779 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 47476, 67210, 49875, 46842, 33201, 83378, 84233, 64708, 85041, 84234, 21617, 55562, 23566, 33489, or 57779 gene has been introduced or disrupted. The invention still further provides isolated 47476, 67210, 49875, 46842, 33201, 83378, 84233, 64708, 85041, 84234, 21617, 55562, 23566, 33489, or 57779 proteins, fusion proteins, antigenic peptides and anti-47476, 67210, 49875, 46842, 33201, 83378, 84233, 64708, 85041, 84234, 21617, 55562, 23566, 33489, or 57779 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.

    摘要翻译： 本发明提供编码新的人基因的分离的核酸分子，命名为47476,67210,49875,46842,33201,83378,84233,64708,85041,84234,21617,55562,23566,33489和57779核酸分子。 本发明还提供反义核酸分子，包含47476,67210,49875,4642,33201,83378,84233,64708,85041,84234,161617,55562,23566,33489或57779核酸分子的重组表达载体，宿主细胞 已经引入了表达载体的非人类转基因动物，以及引入了47476,67210,49875,4642,43708,85041,84234,16617,55562,23566,33489或57779基因的非人类转基因动物，或 中断了 本发明还进一步提供分离的47476,67210,49875,4642,33201,83378,84233,64708,85041,84234,21617,55562,23566,33489或57779号蛋白，融合蛋白，抗原肽和抗-47476,67210， 49875,4462,33201,83378,84233,66708,85041,84234,21617,55562,253566,33489或57779抗体。 还提供了利用本发明组合物的诊断方法。

    Novel 13237, 18480, 2245, 16228, 7677, 26320, 46619, 33166, 16836, 46867, 21617, 55562, 39228, 62088, 46745, 23155, 21657, 42755, 32229, 22325, 46863 and 32252 molecules and uses therefor
    7.
    发明申请
    Novel 13237, 18480, 2245, 16228, 7677, 26320, 46619, 33166, 16836, 46867, 21617, 55562, 39228, 62088, 46745, 23155, 21657, 42755, 32229, 22325, 46863 and 32252 molecules and uses therefor 失效
    小分子13237,18480,2245,16228,7677,26320,46169,36166,16836,46867,21617,55562,39228,62088,4675,23155,26657,42755,32229,22325,46863和32252分子及其用途

    公开(公告)号：US20090263860A1

    公开(公告)日：2009-10-22

    申请号：US11980299

    申请日：2007-10-30

    申请人： Rachel E. Meyers ,  Mark J. Williamson ,  Rosana Kapeller-Libermann ,  Kyle J. MacBeth ,  John Joseph Hunter ,  Laura A. Rudolph-Owen ,  Rajasekhar Bandaru ,  Fong-Ying Tsai

    发明人： Rachel E. Meyers ,  Mark J. Williamson ,  Rosana Kapeller-Libermann ,  Kyle J. MacBeth ,  John Joseph Hunter ,  Laura A. Rudolph-Owen ,  Rajasekhar Bandaru ,  Fong-Ying Tsai

    IPC分类号： C12P21/02 ,  C12N15/11 ,  C12N15/00 ,  C12N5/06

    CPC分类号： C12N9/1205 ,  A01K2217/05 ,  A61K48/00 ,  C07K2319/00

    摘要： The invention provides isolated nucleic acids molecules, designated 13237, 18480, 2245, 16228, 7677, 26320, 46619, 33166, 16836, 46867, 21617, 55562, 39228, 62088, 46745, 23155, 21657, 42755, 32229, 22325, 46863 and 32252 nucleic acid molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 13237, 18480, 2245, 16228, 7677, 26320, 46619, 33166, 16836, 46867, 21617, 55562, 39228, 62088, 46745, 23155, 21657, 42755, 32229, 22325, 46863 and 32252 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 13237, 18480, 2245, 16228, 7677, 26320, 46619, 33166, 16836, 46867, 21617, 55562, 39228, 62088, 46745, 23155, 21657, 42755, 32229, 22325, 46863 or 32252 gene has been introduced or disrupted. The invention still further provides isolated 13237, 18480, 2245, 16228, 7677, 26320, 46619, 33166, 16836, 46867, 21617, 55562, 39228, 62088, 46745, 23155, 21657, 42755, 32229, 22325, 46863 or 32252 proteins, fusion proteins, antigenic peptides and anti-13237, 18480, 2245, 16228, 7677, 26320, 46619, 33166, 16836, 46867, 21617, 55562, 39228, 62088, 46745, 23155, 21657, 42755, 32229, 22325, 46863 or 32252 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.

    摘要翻译： 本发明提供分离的核酸分子，命名为13237,18480,2225,16228,7677,26320,4619,33166,16836,46867,21617,55562,39228,62088,46745,23155,21657,42755,32229,22325,46863 和32252个核酸分子。 本发明还提供反义核酸分子，重组表达载体，其含有13237,18480,2245,16228,7677,26320,4619,33166,16836,46867,21617,55562,39228,62088,46745,23155,216575,42755,32229 ，22325,46863和32252核酸分子，其中引入了表达载体的宿主细胞，以及非人类转基因动物，其中13237,18480,2362,46169,3677,26320,46869,38166,16836,46867,21617,26173,26169， 已经引入或破坏了55562,39228,62088,4675,23155,21657,42755,32229,22325,46863或32252基因。 本发明还进一步提供分离的13237,18480,2225,16228,7677,26320,4619,33166,16836,46867,21617,55562,39228,62088,46745,23155,21657,42755,32229,22325,46863或32252蛋白质 ，融合蛋白，抗原肽和抗-13237,18480,2225,16228,7677,26320,4619,33166,16836,46867,21617,55562,39228,62088,46745,23155,216547,42755,32229,22325,46863 或32252抗体。 还提供了利用本发明组合物的诊断和治疗方法。

    22109, a novel human thioredoxin family member and uses thereof
    10.
    发明授权
    22109, a novel human thioredoxin family member and uses thereof 失效
    22109，一种新型人硫氧还蛋白家族成员及其用途

    公开(公告)号：US06462187B1

    公开(公告)日：2002-10-08

    申请号：US09882835

    申请日：2001-06-15

    申请人： Rajasekhar Bandaru

    发明人： Rajasekhar Bandaru

    IPC分类号： C07H2104

    CPC分类号： C12N9/0036

    摘要： The invention provides isolated nucleic acids molecules, designated 22109 nucleic acid molecules, which encode novel thioredoxin members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 22109 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 22109 gene has been introduced or disrupted. The invention still further provides isolated 22109 proteins, fusion proteins, antigenic peptides and anti-22109 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.

    摘要翻译： 本发明提供编码新的硫氧还蛋白成员的分离的核酸分子，命名为22109核酸分子。 本发明还提供了反义核酸分子，含有22109个核酸分子的重组表达载体，其中引入了表达载体的宿主细胞，以及导入或破坏了22109基因的非人类转基因动物。 本发明还进一步提供了分离的22109蛋白，融合蛋白，抗原肽和抗-22109抗体。 还提供了利用本发明组合物的诊断方法。