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15 条记录 (耗时 0.028 秒)

    Portable waste packaging device
    7.
    发明授权
    Portable waste packaging device 有权
    便携式废物包装装置

    公开(公告)号：US07866717B2

    公开(公告)日：2011-01-11

    申请号：US12584438

    申请日：2009-09-04

    申请人： Hector Martinez

    发明人： Hector Martinez

    IPC分类号： A01K29/00

    CPC分类号： E01H1/1206 ,  E01H2001/1293

    摘要： A device for collecting and packaging solid waste or toxic material is provided. A first arm and a second arm are coupled with a lever, wherein at least one arm is slidably coupled with the lever. A bag may be positioned in an open position when the first arm is located distally from the second arm, and the bag may be closed by an operator manipulating the arms towards each other. The device may include a motor or a spring or springs to drive the arms towards or away from each other. A plate, a pole and a handle may be coupled with the arms. The plate may be positioned relative to the arms to stabilize the waste or toxic material for insertion into the bag. The bag may include an adhesive, paper, plastic, recycled plastic, cellulose in combination or singularity.

    摘要翻译： 提供了收集和包装固体废物或有毒物质的装置。 第一臂和第二臂与杠杆联接，其中至少一个臂可滑动地与杠杆连接。 当第一臂位于远离第二臂的位置时，袋可以定位在打开位置，并且袋可以由操作者将手臂彼此操纵而关闭。 该装置可以包括马达或弹簧或弹簧以将臂朝向或远离彼此驱动。 板，杆和手柄可以与臂联接。 板可以相对于臂定位，以稳定废物或有毒物质以插入袋中。 该袋可以包括粘合剂，纸，塑料，再循环塑料，纤维素的组合或奇异性。

    Vectors having enhanced expression and methods of making and uses thereof
    8.
    发明授权
    Vectors having enhanced expression and methods of making and uses thereof 失效
    具有增强表达的载体及其制备方法和用途

    公开(公告)号：US6130066A

    公开(公告)日：2000-10-10

    申请号：US79587

    申请日：1998-05-15

    申请人： James Tartaglia ,  William I. Cox ,  Russell Robert Gettig ,  Hector Martinez ,  Enzo Paoletti ,  Steven E. Pincus

    发明人： James Tartaglia ,  William I. Cox ,  Russell Robert Gettig ,  Hector Martinez ,  Enzo Paoletti ,  Steven E. Pincus

    IPC分类号： C12N15/09 ,  A61K35/76 ,  A61K48/00 ,  A61P37/04 ,  C12N15/67 ,  C12N15/85 ,  C12N15/863 ,  C12P21/06

    CPC分类号： C12N15/86 ,  A61K48/00 ,  C12N15/67 ,  C12N15/85 ,  C12N2710/24043 ,  C12N2710/24143 ,  C12N2830/00 ,  C12N2830/60 ,  C12N2840/00

    摘要： Disclosed and claimed are vectors having enhanced expression and methods for making and using them. Enhancement of expression is from substantially co-temporal expression of at least one first nucleic acid molecule and at least one second nucleic acid molecule. The second nucleic acid molecule encodes a transcription factor or a translation factor or a transcription factor and a translation factor. The contemporaneous expression can be from operably linking the first and second nucleic molecules to a single promoter, or from operably linking the first nucleic acid molecule to a first promoter and the second nucleic molecule to a second promoter wherein the first and second promoters function substantially contemporaneously. Thus, the first and second nucleic acid molecules can be at the same locus in the vector, or at different loci. The second nucleic acid molecule can encode: one transcription factor or more than one transcription factor; or one translation factor or more than one translation factor; or at least one transcription factor and at least one translation factor. The transcription factor can be from vaccinia H4L, D6, A7, G8R, A1L, A2L, H5R, or combinations thereof. The translation factor can be from a K3L open reading frame, an E3L open reading frame, a VAI RNA, an EBER RNA, a sigma 3 open reading frame, a TRBP open reading frame, or combinations thereof. The vector can be a poxvirus such as an attenuated poxvirus, e.g., NYVAC, or ALVAC.

    摘要翻译： 披露和要求保护的是具有增强的表达的载体和用于制备和使用它们的方法。 表达的增强来自至少一种第一核酸分子和至少一种第二核酸分子的基本上同时表达。 第二核酸分子编码转录因子或翻译因子或转录因子和翻译因子。 同时表达可以是将第一和第二核酸分子可操作地连接到单个启动子，或者可操作地将第一核酸分子与第一启动子连接，而将第二核酸分子可操作地连接到第二启动子，其中第一和第二启动子基本同时起作用 。 因此，第一和第二核酸分子可以在载体中的相同基因座处或在不同的基因座处。 第二核酸分子可编码：一种转录因子或多于一种转录因子; 或一个翻译因子或多于一个翻译因子; 或至少一个转录因子和至少一个翻译因子。 转录因子可以来自牛痘H4L，D6，A7，G8R，A1L，A2L，H5R或其组合。 翻译因子可以来自K3L开放阅读框，E3L开放阅读框，VAI RNA，EBER RNA，西格玛3开放阅读框，TRBP开放阅读框或其组合。 载体可以是痘病毒，例如减毒痘病毒，例如NYVAC或ALVAC。