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    Design of artificial genes for use as controls in gene expression analysis systems
    2.
    发明授权
    Design of artificial genes for use as controls in gene expression analysis systems 失效
    人工基因设计用作基因表达分析系统中的对照

    公开(公告)号：US06943242B2

    公开(公告)日：2005-09-13

    申请号：US10140545

    申请日：2002-05-07

    申请人： Hrissi Samartzidou ,  Leah Turner ,  Steven Daniel ,  Thomas Houts

    发明人： Hrissi Samartzidou ,  Leah Turner ,  Steven Daniel ,  Thomas Houts

    IPC分类号： C12N15/09 ,  C07H21/02 ,  C07H21/04 ,  C12P19/34 ,  C12Q1/68

    CPC分类号： C12Q1/6809 ,  C12Q2545/101

    摘要： Method of producing controls for use in gene expression analysis systems such as macroarrays, real-time PCR, northern blots, SAGE and microarrays. The controls are generated either from near-random sequence of DNA, or from inter- or intragenic regions of a genome. Ten specific control sequences are also disclosed. Also presented are methods of using these controls, including as negative controls, positive controls, and as calibrators of a gene expression analysis system.

    摘要翻译： 生产用于基因表达分析系统如大阵列，实时PCR，Northern印迹，SAGE和微阵列的对照的方法。 对照是从DNA的近随机序列或基因组的内部或内部区域产生的。 还公开了10个特异性控制序列。 还提出了使用这些对照的方法，包括作为阴性对照，阳性对照和作为基因表达分析系统的校准物。

    Thermal coagulation of tissue during tissue resection
    3.
    发明申请
    Thermal coagulation of tissue during tissue resection 有权
    组织切除期间组织的热凝固

    公开(公告)号：US20050070896A1

    公开(公告)日：2005-03-31

    申请号：US10890055

    申请日：2004-07-12

    申请人： Steven Daniel ,  David Morris

    发明人： Steven Daniel ,  David Morris

    IPC分类号： A61B18/14 ,  A61B19/00

    CPC分类号： A61B18/1477 ,  A61B90/11 ,  A61B2018/0016 ,  A61B2018/00577 ,  A61B2018/1425 ,  A61B2018/143 ,  A61B2018/1475

    摘要： A coagulation system is provided for use in biological tissue. The coagulation system includes a handle, a radiofrequency (RF) generator, and an electrode array. The electrode array includes two or more pair of bipolar electrodes slideably coupled in channels of the handle. The bipolar electrodes electrically couple to the RF generator, and the electrode array is configured to deliver a balanced energy density in a target volume of the biological tissue. The balanced energy density delivered by the electrode array results in thermal coagulation necrosis of a rectangular volume of biological tissue.

    摘要翻译： 提供用于生物组织的凝血系统。 凝结系统包括手柄，射频（RF）发生器和电极阵列。 电极阵列包括可滑动地联接在手柄的通道中的两对或更多对双极电极。 双极电极电耦合到RF发生器，并且电极阵列被配置为在生物组织的靶体积中传递平衡的能量密度。 由电极阵列传递的平衡能量密度导致生物组织的矩形体积的热凝固坏死。

    Variable wheelbase motor grader
    5.
    发明授权
    Variable wheelbase motor grader 有权
    可变轴距电机分级机

    公开(公告)号：US08393429B2

    公开(公告)日：2013-03-12

    申请号：US12938861

    申请日：2010-11-03

    申请人： Norval Thomson ,  Steven Daniel ,  Daniel Sergison

    发明人： Norval Thomson ,  Steven Daniel ,  Daniel Sergison

    IPC分类号： B62D61/12 ,  B62K13/00

    CPC分类号： E02F5/32 ,  B62D49/0678 ,  E02F3/764 ,  E02F3/7659 ,  E02F3/7668 ,  E02F3/7672 ,  E02F3/961 ,  E02F9/024 ,  E02F9/225

    摘要： A motor grader with an adjustable wheelbase. The motor grader may include front and rear wheels supporting a chassis and a main frame. A working blade may downwardly depend from the main frame between the front wheels and rear wheels to perform work on the ground below. The motor grader may also provide an adjustable wheel base to allow the center of gravity of the motor grader to better match the work load being addressed. The adjustable wheel base may also provide more swing clearance for the blade relative to the rear wheels, allow for an adjustable articulation angle, and minimize structural loads on the motor grader, particularly during ripping operation. The wheel base may be adjustable by providing structure through which the relative positions of the rear wheels can be altered automatically, manually, and dynamically.

    摘要翻译： 具有可调节轴距的自动平地机。 自动平地机可以包括支撑底盘和主框架的前轮和后轮。 工作叶片可以从前轮和后轮之间的主框架向下依次，以在下面的地面上进行作业。 自动平地机还可以提供可调轮盘，以允许分级机的重心更好地匹配要解决的工作负荷。 可调轮底还可以为叶片相对于后轮提供更多的摆动间隙，允许可调节的关节角度，并且最小化马达分级机上的结构负载，特别是在翻转操作期间。 车轮底座可以通过提供可以自动，手动和动态地改变后轮的相对位置的结构来调节。

    Thermal hemostasis and/or coagulation of tissue
    6.
    发明申请
    Thermal hemostasis and/or coagulation of tissue 审中-公开
    热止血和/或凝血组织

    公开(公告)号：US20060100620A1

    公开(公告)日：2006-05-11

    申请号：US11256500

    申请日：2005-10-20

    申请人： Steven Daniel ,  David Morris

    发明人： Steven Daniel ,  David Morris

    IPC分类号： A61B18/14

    CPC分类号： A61B18/1477 ,  A61B2018/0016 ,  A61B2018/1425 ,  A61B2018/1467 ,  A61B2018/1475

    摘要： Energy delivery systems and methods are provided for use in biological tissue. The energy delivery system includes a handle, a radiofrequency (RF) generator, and an electrode array. The electrode array includes two or more pair of bipolar electrodes slideably coupled in channels of the handle. The bipolar electrodes electrically couple to the RF generator, and the electrode array is configured to deliver a balanced energy density in a target volume of the biological tissue. The balanced energy density delivered by the electrode array results in generation of a hemostatic plane of tissue.

    摘要翻译： 提供能量输送系统和方法用于生物组织。 能量输送系统包括手柄，射频（RF）发生器和电极阵列。 电极阵列包括可滑动地联接在手柄的通道中的两对或更多对双极电极。 双极电极电耦合到RF发生器，并且电极阵列被配置为在生物组织的靶体积中传递平衡的能量密度。 由电极阵列传递的平衡能量密度导致组织的止血平面的产生。

    Training device for an ambulatory user
    8.
    发明授权
    Training device for an ambulatory user 有权
    用于移动用户的训练装置

    公开(公告)号：US08100816B2

    公开(公告)日：2012-01-24

    申请号：US11724598

    申请日：2007-03-14

    申请人： Steven Daniel

    发明人： Steven Daniel

    IPC分类号： A63B21/06 ,  A63B71/00

    CPC分类号： A63B69/0028 ,  A63B21/0618 ,  A63B21/065 ,  A63B21/4007 ,  A63B21/4009 ,  A63B22/20 ,  B62B5/068

    摘要： A training device for an ambulatory user is disclosed. The training device includes a harness to attach to the ambulatory user, a pair of wheels extending from opposite sides of a crossbar, and a weight holder connected between the crossbar and the harness. The weight holder is adapted to hold one or more removable weights. The training device can further include an elongated shock absorber connected to the harness to absorb compressive and expansive forces exerted on the harness at least in part by the ambulatory user.

    摘要翻译： 公开了一种用于移动用户的训练装置。 该训练装置包括一个附着到走动用户的线束，一对从横杆的相对侧延伸的轮子，以及连接在横梁和线束之间的重量保持架。 重量保持器适于容纳一个或多个可拆卸的重物。 训练装置还可以包括连接到线束的细长的减震器，以至少部分地由移动用​​户吸收施加在线束上的压缩和膨胀力。

    Variable Wheelbase Motor Grader
    9.
    发明申请
    Variable Wheelbase Motor Grader 有权
    可变轴距自动平地机

    公开(公告)号：US20110108294A1

    公开(公告)日：2011-05-12

    申请号：US12938861

    申请日：2010-11-03

    申请人： Norval Thomson ,  Steven Daniel ,  Daniel Sergison

    发明人： Norval Thomson ,  Steven Daniel ,  Daniel Sergison

    IPC分类号： E02F3/84 ,  E02F3/76 ,  E02F3/80

    CPC分类号： E02F5/32 ,  B62D49/0678 ,  E02F3/764 ,  E02F3/7659 ,  E02F3/7668 ,  E02F3/7672 ,  E02F3/961 ,  E02F9/024 ,  E02F9/225

    摘要： A motor grader with an adjustable wheel base is disclosed. The motor grader may include front and rear wheels supporting a chassis and a main frame. A working blade may downwardly depend from the main frame between the front wheels and rear wheels to perform work on the ground below. The motor grader may also provide an adjustable wheel base to allow the center of gravity of the motor grader to better match the work load being addressed. The adjustable wheel base may also provide more swing clearance for the blade relative to the rear wheels, allow for an adjustable articulation angle, and minimize structural loads on the motor grader, particularly during ripping operation. The wheel base may be adjustable by providing structure through which the relative positions of the rear wheels can be altered automatically, manually, and dynamically.

    摘要翻译： 公开了一种具有可调轮毂的平地机。 自动平地机可以包括支撑底盘和主框架的前轮和后轮。 工作叶片可以从前轮和后轮之间的主框架向下依次，以在下面的地面上进行作业。 自动平地机还可以提供可调轮盘，以允许分级机的重心更好地匹配要解决的工作负荷。 可调轮底还可以为叶片相对于后轮提供更多的摆动间隙，允许可调节的关节角度，并且最小化马达分级机上的结构负载，特别是在翻转操作期间。 车轮底座可以通过提供可以自动，手动和动态地改变后轮的相对位置的结构来调节。

    Apparatus and method for tissue resection
    10.
    发明申请
    Apparatus and method for tissue resection 审中-公开
    组织切除术的装置和方法

    公开(公告)号：US20060142757A1

    公开(公告)日：2006-06-29

    申请号：US11335092

    申请日：2006-01-18

    申请人： Steven Daniel ,  David Morris

    发明人： Steven Daniel ,  David Morris

    IPC分类号： A61B18/14

    CPC分类号： A61B18/1477 ,  A61B90/11 ,  A61B2018/0016 ,  A61B2018/00577 ,  A61B2018/1425 ,  A61B2018/143 ,  A61B2018/1475

    摘要： A tissue ablation system is described that generates a uniform avascular plane of coagulated tissue to aid in the bloodless or near-bloodless resection of various biological tissues from a variety of organs. The tissue ablation system includes an energy director guide and two or more sets of bipolar energy directors. The energy director guide includes a series of channels that configure the energy directors to provide approximately uniform power distribution or current density through a target tissue volume or plane. The spacing among the channels of the energy director guide varies according to the total number of energy directors received in the energy director guide so that relative spacing among the center-most channels is largest and relative spacing among the end-most channels is smallest. The energy director guide secures a selected position of each of the energy directors in the target tissue volume.

    摘要翻译： 描述了组织消融系统，其产生凝固组织的均匀的无血管平面，以帮助来自各种器官的各种生物组织的无血或近无血的切除。 组织消融系统包括能量导向器引导件和两组或多组双极能量引导器。 能量导向器引导件包括一系列通道，其配置能量引导器以通过目标组织体积或平面提供近似均匀的功率分布或电流密度。 能量导向器引导件的通道之间的间隔根据能量导向器引导器中接收到的能量引导器的总数而变化，使得最中心的通道之间的相对间隔最大，并且最终通道之间的相对间隔最小。 能量导向器引导件将每个能量引导器的选定位置固定在目标组织体积中。