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    Orthogonal ion sampling for electrospray .[.LC/MS.]. mass spectrometry
    5.
    再颁专利
    Orthogonal ion sampling for electrospray .[.LC/MS.]. mass spectrometry 失效
    电喷雾正交离子采样[LC / MS]质谱

    公开(公告)号：USRE36892E

    公开(公告)日：2000-10-03

    申请号：US792303

    申请日：1997-01-31

    申请人： James A. Apffel, Jr. ,  Mark H. Werlich ,  James L. Bertsch ,  Paul C. Goodley ,  Kent D. Henry

    发明人： James A. Apffel, Jr. ,  Mark H. Werlich ,  James L. Bertsch ,  Paul C. Goodley ,  Kent D. Henry

    IPC分类号： G01N27/62 ,  G01N30/72 ,  H01J49/04 ,  B01D59/46 ,  H01J49/00

    CPC分类号： H01J49/165 ,  G01N30/7253 ,  H01J49/04

    摘要： .[.The invention teaches the uses of a plurality of electric fields and of orthogonal spray configurations of vaporized analyte which combine so as to operate to enhance the efficiency of analyte detection and mass analysis with a mass spectrometer by reducing vapor in the vacuum system and concomitant noise. Several embodiments of the invention are described for purposes of illustration..]. .Iadd.The invention relates to a method and apparatus for improving signal relative to noise without loss of ion collection efficiency in electrospray mass spectrometry, including liquid chromatography/mass spectrometry..Iaddend.

    摘要翻译： [本发明教导了多个电场和汽化分析物的正交喷雾构型的使用，其结合起来以便通过减少真空系统中的蒸气和伴随的噪声来提高分析物检测和质谱分析的效率 。 为了说明的目的，描述了本发明的几个实施例。]本发明涉及一种用于在电喷雾质谱（包括液相色谱/质谱）中改善相对于噪声的信号而不损失离子收集效率的方法和装置。

    Method and apparatus for surface desorption ionization by charged particles
    10.
    发明授权
    Method and apparatus for surface desorption ionization by charged particles 有权
    带电粒子表面解吸电离的方法和装置

    公开(公告)号：US07723678B2

    公开(公告)日：2010-05-25

    申请号：US11398305

    申请日：2006-04-04

    申请人： Jean-Luc Truche ,  Paul C. Goodley ,  Gregor Overney

    发明人： Jean-Luc Truche ,  Paul C. Goodley ,  Gregor Overney

    IPC分类号： H01J49/14

    CPC分类号： H01J49/142

    摘要： An apparatus and method for generating analyte ions from a sample. An ion generating device is provided having a chamber with an outlet and a surface having a material and means for applying a high velocity gas flow through the chamber toward the outlet such that charged particles are produced by physical interaction between the high velocity gas and the material. The charged particles then induce the generation of primary ions by interaction with molecules of the high velocity gas. The primary ions are emitted from the outlet of the ion generating device toward a sample-bearing surface and analyte ions are generated by impact of the primary ions on the analyte sample on the surface.

    摘要翻译： 一种用于从样品中产生分析物离子的装置和方法。 提供一种离子产生装置，其具有具有出口的腔室和具有材料的表面，以及用于将高速气流经由腔室朝向出口施加的装置，使得通过高速气体和材料之间的物理相互作用产生带电粒子 。 带电粒子然后通过与高速气体分子的相互作用诱导产生初级离子。 主要离子从离子产生装置的出口朝向样品承载表面发射，分析物离子通过主离子冲击表面上的分析物样品而产生。