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公开(公告)号:US20130006351A1
公开(公告)日:2013-01-03
申请号:US13605904
申请日:2012-09-06
申请人: Doug Taylor , Jim McClain , Clint Smoke , Mike Cole , James DeYoung
发明人: Doug Taylor , Jim McClain , Clint Smoke , Mike Cole , James DeYoung
IPC分类号: A61F2/06 , A61P3/10 , A61P29/00 , A61P9/12 , A61P1/04 , A61K38/02 , A61K38/43 , A61P25/16 , A61K31/551 , A61K31/436 , B32B5/00 , B32B27/30 , B32B27/32 , B32B27/40 , B32B27/36 , B32B27/00 , A61K9/00
CPC分类号: A61F2/82 , A61F2210/0076 , A61F2250/0067 , A61L31/10 , A61L31/16 , A61L2300/416 , A61L2300/426 , A61L2300/606 , A61L2300/63 , A61L2420/08 , Y10T428/264 , Y10T428/265 , Y10T428/31507 , Y10T428/31544 , Y10T428/31551 , Y10T428/31663 , Y10T428/31786 , Y10T428/31935 , Y10T428/31938
摘要: A method for depositing a coating comprising a polymer and pharmaceutical agent on a substrate, comprising the following steps: discharging at least one pharmaceutical agent in a therapeutically desirable morphology in dry powder form through a first orifice; discharging at least one polymer in dry powder form through a second orifice; depositing the polymer and/or pharmaceutical particles onto said substrate, wherein an electrical potential is maintained between the substrate and the pharmaceutical and/or polymer particles, thereby forming said coating; and sintering said coating under conditions that do not substantially modify the morphology of said pharmaceutical agent.
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公开(公告)号:US08298565B2
公开(公告)日:2012-10-30
申请号:US11995687
申请日:2006-07-14
申请人: Doug Taylor , Jim McClain , Clint Smoke , Mike Cole , James DeYoung
发明人: Doug Taylor , Jim McClain , Clint Smoke , Mike Cole , James DeYoung
IPC分类号: A61F2/00 , A61K31/436 , B05D7/02
CPC分类号: A61F2/82 , A61F2210/0076 , A61F2250/0067 , A61L31/10 , A61L31/16 , A61L2300/416 , A61L2300/426 , A61L2300/606 , A61L2300/63 , A61L2420/08 , Y10T428/264 , Y10T428/265 , Y10T428/31507 , Y10T428/31544 , Y10T428/31551 , Y10T428/31663 , Y10T428/31786 , Y10T428/31935 , Y10T428/31938
摘要: A method for depositing a coating comprising a polymer and pharmaceutical agent on a substrate, comprising the following steps: discharging at least one pharmaceutical agent in a therapeutically desirable morphology in dry powder form through a first orifice; discharging at least one polymer in dry powder form through a second orifice; depositing the polymer and/or pharmaceutical particles onto the substrate, wherein an electrical potential is maintained between the substrate and the pharmaceutical and/or polymer particles, thereby forming the coating; and sintering the coating under conditions that do not substantially modify the morphology of the pharmaceutical agent.
摘要翻译: 一种用于在基底上沉积包含聚合物和药剂的涂层的方法,包括以下步骤:通过第一孔排出至少一种治疗上需要的干粉形式的药剂; 通过第二孔排出至少一种干粉形式的聚合物; 将聚合物和/或药物颗粒沉积到基底上,其中在基底和药物和/或聚合物颗粒之间保持电位,从而形成涂层; 并在不显着改变药剂形态的条件下烧结涂层。
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公开(公告)号:US20090123515A1
公开(公告)日:2009-05-14
申请号:US11995687
申请日:2006-07-14
申请人: Doug Taylor , Jim McClain , Clint Smoke , Mike Cole , James DeYoung
发明人: Doug Taylor , Jim McClain , Clint Smoke , Mike Cole , James DeYoung
IPC分类号: A61F2/00 , A61K31/436 , B05D7/02
CPC分类号: A61F2/82 , A61F2210/0076 , A61F2250/0067 , A61L31/10 , A61L31/16 , A61L2300/416 , A61L2300/426 , A61L2300/606 , A61L2300/63 , A61L2420/08 , Y10T428/264 , Y10T428/265 , Y10T428/31507 , Y10T428/31544 , Y10T428/31551 , Y10T428/31663 , Y10T428/31786 , Y10T428/31935 , Y10T428/31938
摘要: A method for depositing a coating comprising a polymer and pharmaceutical agent on a substrate, comprising the following steps: discharging at least one pharmaceutical agent in a therapeutically desirable morphology in dry powder form through a first orifice; discharging at least one polymer in dry powder form through a second orifice; depositing the polymer and/or pharmaceutical particles onto said substrate, wherein an electrical potential is maintained between the substrate and the pharmaceutical and/or polymer particles, thereby forming said coating; and sintering said coating under conditions that do not substantially modify the morphology of said pharmaceutical agent.
摘要翻译: 一种用于在基底上沉积包含聚合物和药剂的涂层的方法,包括以下步骤:通过第一孔排出至少一种治疗上需要的干粉形式的药剂; 通过第二孔排出至少一种干粉形式的聚合物; 将所述聚合物和/或药物颗粒沉积到所述基底上,其中在所述基底和所述药物和/或聚合物颗粒之间保持电位,从而形成所述涂层; 并且在基本上不改变所述药剂的形态的条件下烧结所述涂层。
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公开(公告)号:US20090186069A1
公开(公告)日:2009-07-23
申请号:US12298459
申请日:2007-04-26
申请人: James DeYoung , Doug Taylor , Jim McClain , Clint Smoke , Mike Cole
发明人: James DeYoung , Doug Taylor , Jim McClain , Clint Smoke , Mike Cole
CPC分类号: A61L31/16 , A61F2/90 , A61F2210/0004 , A61F2250/0067 , A61L31/06 , A61L31/10 , A61L31/148 , A61L2300/20 , A61L2300/216 , A61L2300/236 , A61L2300/416 , A61L2300/42 , A61L2300/426 , A61L2300/602 , A61L2300/608 , A61L2300/61 , A61L2420/02 , A61L2420/06 , A61L2420/08
摘要: A method for depositing a coating comprising a polymer and at least two pharmaceutical agents on a substrate, comprising the following steps: providing a stent framework; depositing on said stent framework a first layer comprising a first pharmaceutical agent; depositing a second layer comprising a second pharmaceutical agent; Wherein said first and second pharmaceutical agents are selected from two different classes of pharmaceutical agents.
摘要翻译: 一种用于在基底上沉积包含聚合物和至少两种药剂的涂层的方法,包括以下步骤:提供支架框架; 在所述支架框架上沉积包含第一药剂的第一层; 沉积包含第二药剂的第二层; 其中所述第一和第二药剂选自两种不同类型的药剂。
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公开(公告)号:US08852625B2
公开(公告)日:2014-10-07
申请号:US12298459
申请日:2007-04-26
申请人: James DeYoung , Doug Taylor , Jim McClain , Clint Smoke , Mike Cole
发明人: James DeYoung , Doug Taylor , Jim McClain , Clint Smoke , Mike Cole
CPC分类号: A61L31/16 , A61F2/90 , A61F2210/0004 , A61F2250/0067 , A61L31/06 , A61L31/10 , A61L31/148 , A61L2300/20 , A61L2300/216 , A61L2300/236 , A61L2300/416 , A61L2300/42 , A61L2300/426 , A61L2300/602 , A61L2300/608 , A61L2300/61 , A61L2420/02 , A61L2420/06 , A61L2420/08
摘要: A method for depositing a coating comprising a polymer and at least two pharmaceutical agents on a substrate, comprising the following steps: providing a stent framework; depositing on said stent framework a first layer comprising a first pharmaceutical agent; depositing a second layer comprising a second pharmaceutical agent; Wherein said first and second pharmaceutical agents are selected from two different classes of pharmaceutical agents.
摘要翻译: 一种用于在基底上沉积包含聚合物和至少两种药剂的涂层的方法,包括以下步骤:提供支架框架; 在所述支架框架上沉积包含第一药剂的第一层; 沉积包含第二药剂的第二层; 其中所述第一和第二药剂选自两种不同类型的药剂。
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公开(公告)号:US08758429B2
公开(公告)日:2014-06-24
申请号:US13605904
申请日:2012-09-06
申请人: Doug Taylor , Jim McClain , Clint Smoke , Mike Cole , James DeYoung
发明人: Doug Taylor , Jim McClain , Clint Smoke , Mike Cole , James DeYoung
IPC分类号: A61F2/06
CPC分类号: A61F2/82 , A61F2210/0076 , A61F2250/0067 , A61L31/10 , A61L31/16 , A61L2300/416 , A61L2300/426 , A61L2300/606 , A61L2300/63 , A61L2420/08 , Y10T428/264 , Y10T428/265 , Y10T428/31507 , Y10T428/31544 , Y10T428/31551 , Y10T428/31663 , Y10T428/31786 , Y10T428/31935 , Y10T428/31938
摘要: A method for depositing a coating comprising a polymer and pharmaceutical agent on a substrate, comprising the following steps: discharging at least one pharmaceutical agent in a therapeutically desirable morphology in dry powder form through a first orifice; discharging at least one polymer in dry powder form through a second orifice; depositing the polymer and/or pharmaceutical particles onto said substrate, wherein an electrical potential is maintained between the substrate and the pharmaceutical and/or polymer particles, thereby forming said coating; and sintering said coating under conditions that do not substantially modify the morphology of said pharmaceutical agent.
摘要翻译: 一种用于在基底上沉积包含聚合物和药剂的涂层的方法,包括以下步骤:通过第一孔排出至少一种治疗上需要的干粉形式的药剂; 通过第二孔排出至少一种干粉形式的聚合物; 将所述聚合物和/或药物颗粒沉积到所述基底上,其中在所述基底和所述药物和/或聚合物颗粒之间保持电位,从而形成所述涂层; 并且在不显着改变所述药剂的形态的条件下烧结所述涂层。
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公开(公告)号:US20050161819A1
公开(公告)日:2005-07-28
申请号:US10762905
申请日:2004-01-22
申请人: James DeYoung , James McClain , Stephen Gross , Doug Taylor , Mark Wagner , David Brainard
发明人: James DeYoung , James McClain , Stephen Gross , Doug Taylor , Mark Wagner , David Brainard
IPC分类号: H01L21/288 , H01L21/3205 , H01L21/4763 , H01L21/768 , H01L23/48 , H01L23/52 , H01L29/40
CPC分类号: H01L21/32051 , H01L21/283 , H01L21/288 , H01L21/76814 , H01L21/76843 , H01L21/76871
摘要: A method of treating a dielectric surface portion of a semiconductor substrate, comprising the steps of: (a) providing a semiconductor substrate having a dielectric surface portion; and then (b) treating said dielectric surface portion with a coating reagent, the coating reagent comprising a reactive group coupled to a coordinating group, with the coordinating group having a metal bound thereto, so that the metal is deposited on the dielectric surface portion to produce a surface portion treated with a metal.
摘要翻译: 一种处理半导体衬底的电介质表面部分的方法,包括以下步骤:(a)提供具有电介质表面部分的半导体衬底; 然后(b)用涂层试剂处理所述电介质表面部分,所述涂覆试剂包含与配位基团偶联的反应基团,所述配位基团与其结合金属,使得金属沉积在电介质表面部分上 产生用金属处理的表面部分。
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公开(公告)号:US20060035014A1
公开(公告)日:2006-02-16
申请号:US11261299
申请日:2005-10-28
申请人: James DeYoung , James McClain , Stephen Gross , Doug Taylor , Mark Wagner , David Brainard
发明人: James DeYoung , James McClain , Stephen Gross , Doug Taylor , Mark Wagner , David Brainard
IPC分类号: B05D5/12
CPC分类号: H01L21/283 , B05D1/18 , B05D2401/90 , H01L21/28556 , H01L21/288 , H01L21/67028 , H01L28/65
摘要: A method of coating a substrate comprises the steps of: (a) providing a substrate in an enclosed vessel, the substrate having a surface portion; (b) at least partially filling the enclosed vessel with a first supercritical fluid so that said first supercritical fluid contacts the surface portion, with the first supercritical fluid carrying or containing a coating component; then (c) adding a separate compressed gas atmosphere to the reaction vessel so that a boundary is formed between the first supercritical fluid and the separate compressed gas atmosphere, said separate compressed gas atmosphere having a density less than said first supercritical fluid; and then (d) displacing said first supercritical fluid from said vessel by continuing adding said separate compressed gas atmosphere to said vessel so that said boundary moves across said surface portion and a thin film of coating component is deposited on said microelectronic substrate.
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9.
公开(公告)号:US20070154848A1
公开(公告)日:2007-07-05
申请号:US11684672
申请日:2007-03-12
申请人: Mark Wagner , James DeYoung , Merrick Miles , Chris Harbinson
发明人: Mark Wagner , James DeYoung , Merrick Miles , Chris Harbinson
IPC分类号: G03C5/00
摘要: A method for carrying out positive tone lithography with a carbon dioxide development system is carried out by: (a) providing a substrate, the substrate having a polymer resist layer formed thereon, (b) exposing at least one portion of the polymer resist layer to radiant energy causing a chemical shift to take place in the exposed portion and thereby form at least one light field region in the polymer resist layer while concurrently maintaining at least one portion of the polymer layer unexposed to the radiant energy to thereby form at least one dark field region in the polymer resist layer; (c) optionally baking the polymer resist layer; (d) contacting the polymer resist layer to a carbon dioxide solvent system, the solvent system comprising a polar group, under conditions in which the at least one light field region is preferentially removed from the substrate by the carbon dioxide solvent system as compared to the at least one dark field region; wherein the carbon dioxide solvent system comprises a first phase and a second phase, the first phase comprising carbon dioxide and the second phase comprising a polar fluid, with the at least one light field region being preferentially soluble in the polar fluid as compared to the at least one dark field region.
摘要翻译: 通过以下方式进行用二氧化碳显影系统进行正色调光刻的方法:(a)提供衬底,其上形成有聚合物抗蚀剂层的衬底,(b)将至少一部分聚合物抗蚀剂层暴露于 导致在暴露部分发生化学位移的辐射能,从而在聚合物抗蚀剂层中形成至少一个光场区域,同时保持聚合物层的至少一部分未暴露于辐射能,从而形成至少一个黑暗 聚合物抗蚀剂层中的场区域; (c)任选地烘烤聚合物抗蚀剂层; (d)将所述聚合物抗蚀剂层与二氧化碳溶剂体系接触,所述溶剂体系包含极性基团,其中所述至少一个光场区域优选地通过二氧化碳溶剂系统从所述底物除去, 至少一个暗场区域; 其中所述二氧化碳溶剂系统包括第一相和第二相,所述第一相包含二氧化碳,所述第二相包含极性流体,其中所述至少一个光场区域优先溶于极性流体中,与第 至少一个暗场区域。
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10.
公开(公告)号:US20050208429A1
公开(公告)日:2005-09-22
申请号:US11133077
申请日:2005-05-19
申请人: James DeYoung , James McClain
发明人: James DeYoung , James McClain
IPC分类号: G03F20060101 , G03F7/00 , G03F7/32 , G03F7/36
摘要: A method for carrying out positive tone lithography with a carbon dioxide development system is carried out by: (a) providing a substrate, the substrate having a polymer resist layer formed thereon, (b) exposing at least one portion of the polymer resist layer to radiant energy causing a chemical shift to take place in the exposed portion and thereby form at least one light field region in the polymer resist layer while concurrently maintaining at least one portion of the polymer layer unexposed to the radiant energy to thereby form at least one dark field region in the polymer resist layer; (c) optionally baking the polymer resist layer; (d) contacting the polymer resist layer to a carbon dioxide solvent system, the solvent system comprising a polar group, under conditions in which the at least one light field region is preferentially removed from the substrate by the carbon dioxide solvent system as compared to the at least one dark field region; wherein the carbon dioxide solvent system comprises a first phase and a second phase, the first phase comprising carbon dioxide and the second phase comprising a polar fluid, with the at least one light field region being preferentially soluble in the polar fluid as compared to the at least one dark field region.
摘要翻译: 通过以下方式进行用二氧化碳显影系统进行正色调光刻的方法:(a)提供衬底,其上形成有聚合物抗蚀剂层的衬底,(b)将至少一部分聚合物抗蚀剂层暴露于 导致在暴露部分发生化学位移的辐射能,从而在聚合物抗蚀剂层中形成至少一个光场区域,同时保持聚合物层的至少一部分未暴露于辐射能,从而形成至少一个黑暗 聚合物抗蚀剂层中的场区域; (c)任选地烘烤聚合物抗蚀剂层; (d)将所述聚合物抗蚀剂层与二氧化碳溶剂体系接触,所述溶剂体系包含极性基团,其中所述至少一个光场区域优选地通过二氧化碳溶剂系统从所述底物除去, 至少一个暗场区域; 其中所述二氧化碳溶剂系统包括第一相和第二相,所述第一相包含二氧化碳,所述第二相包含极性流体,其中所述至少一个光场区域优先溶于极性流体中,与第 至少一个暗场区域。
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