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    Genetically encoded fluorescent coumarin amino acids
    1.
    发明申请
    Genetically encoded fluorescent coumarin amino acids 失效
    遗传编码荧光香豆素氨基酸

    公开(公告)号：US20080044886A1

    公开(公告)日：2008-02-21

    申请号：US11805247

    申请日：2007-05-21

    Applicant: Jiangyun Wang ,  Jianming Xie ,  Peter Schultz

    Inventor： Jiangyun Wang ,  Jianming Xie ,  Peter Schultz

    IPC: C07H21/04 ,  C07K16/00 ,  C12N1/20 ,  C12N15/00

    CPC classification number: C12P21/02 ,  C12N9/93 ,  C12N15/10 ,  C12N15/67

    Abstract: The invention relates to orthogonal pairs of tRNAs and aminoacyl-tRNA synthetases that can incorporate the coumarin unnatural amino acid L-(7-hydroxycoumarin-4-yl) ethylglycine into proteins produced in eubacterial host cells such as E. coli. The invention provides, for example but not limited to, novel orthogonal synthetases, methods for identifying and making the novel synthetases, methods for producing proteins containing the unnatural amino acid L-(7-hydroxycoumarin-4-yl)ethylglycine and related translation systems.

    Abstract translation: 本发明涉及tRNA和氨酰-tRNA合成酶的正交对，其可以将香豆素非天然氨基酸L-（7-羟基香豆素-4-基）乙基甘氨酸掺入到在细菌宿主细胞如大肠杆菌中产生的蛋白质中。 本发明提供了例如但不限于新型正交合成酶，用于鉴定和制备新合成酶的方法，用于产生含有非天然氨基酸L-（7-羟基香豆素-4-基）乙基甘氨酸的蛋白质的方法和相关翻译系统。

    Genetically programmed expression of proteins containing the unnatural amino acid phenylselenocysteine
    2.
    发明申请
    Genetically programmed expression of proteins containing the unnatural amino acid phenylselenocysteine 有权
    含有非天然氨基酸苯基硒代半胱氨酸的蛋白质的遗传程序表达

    公开(公告)号：US20070238152A1

    公开(公告)日：2007-10-11

    申请号：US11724039

    申请日：2007-03-13

    Applicant: Jiangyun Wang ,  Peter Schultz

    Inventor： Jiangyun Wang ,  Peter Schultz

    IPC: C12P21/06 ,  C12N9/22 ,  C07K14/195 ,  C12N15/74 ,  C12N1/21

    CPC classification number: C12N9/104 ,  C12N9/93 ,  C12N15/67 ,  C12P21/02

    Abstract: The invention relates to orthogonal pairs of tRNAs and aminoacyl-tRNA synthetases that can incorporate the unnatural amino acid phenylselenocysteine into proteins produced in eubacterial host cells such as E. coli. The invention provides, for example but not limited to, novel orthogonal aminoacyl-tRNA synthetases, polynucleotides encoding the novel synthetase molecules, methods for identifying and making the novel synthetases, methods for producing proteins containing the unnatural amino acid phenylselenocysteine and translation systems. The invention further provides methods for producing modified proteins (e.g., lipidated proteins) through targeted modification of the phenylselenocysteine residue in a protein.

    Abstract translation: 本发明涉及tRNA和氨酰-tRNA合成酶的正交对，其可以将非天然氨基酸苯硒代半胱氨酸掺入到在细菌宿主细胞如大肠杆菌中产生的蛋白质中。 本发明提供了例如但不限于新型正交氨酰-tRNA合成酶，编码新合成酶分子的多核苷酸，用于鉴定和制备新合成酶的方法，用于产生含有非天然氨基酸苯基硒半胱氨酸的蛋白质的翻译方法和翻译系统。 本发明还提供了通过蛋白质中的苯基硒代半胱氨酸残基的靶向修饰产生修饰的蛋白质（例如，脂质化蛋白质）的方法。

    Wing chair
    7.
    外观设计
    Wing chair 有权
    翼椅

    公开(公告)号：USD619385S1

    公开(公告)日：2010-07-13

    申请号：US29315708

    申请日：2009-07-16

    Applicant: Peter Schultz

    Designer： Peter Schultz

    Separation of Propylene Oxide from a Mixture Comprising Propylene Oxide and Methanol
    9.
    发明申请
    Separation of Propylene Oxide from a Mixture Comprising Propylene Oxide and Methanol 有权
    从包含环氧丙烷和甲醇的混合物中分离出环氧丙烷

    公开(公告)号：US20090118523A1

    公开(公告)日：2009-05-07

    申请号：US11631843

    申请日：2005-07-06

    Applicant: Hans-Georg Gobbel ,  Henning Schultz ,  Peter Schultz ,  Renate Patrascu ,  Malte Schultz ,  Meinolf Weidenbach

    Inventor： Hans-Georg Gobbel ,  Henning Schultz ,  Peter Schultz ,  Renate Patrascu ,  Malte Schultz ,  Meinolf Weidenbach

    IPC: C07D301/32

    CPC classification number: C07D301/32 ,  C07D301/12

    Abstract: A method of separating propylene oxide from a mixture (M) comprising propylene oxide and methanol, said method comprising: (i) introducing said mixture (M) into an extractive distillation column; (ii) additionally introducing an extracting solvent into said extractive distillation column; (iii) distilling propylene oxide overhead from said extractive distillation column as top stream; (iv) withdrawing a bottoms stream from said extractive distillation column; (v) compressing the top stream obtained overhead in (iii) by means of at least one compressor to give a compressed vapor.

    Abstract translation: 一种从包含环氧丙烷和甲醇的混合物（M）中分离环氧丙烷的方法，所述方法包括：（i）将所述混合物（M）引入萃取蒸馏塔; （ii）另外将萃取溶剂引入所述​​萃取蒸馏塔中; （iii）从所述萃取蒸馏塔顶部馏出环氧丙烷作为顶部流; （iv）从所述萃取蒸馏塔中取出塔底物​​流; （v）通过至少一个压缩机压缩在（iii）中获得的塔顶馏出物的顶部流以产生压缩蒸汽。

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