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    Bacteria and method for controlling plant disease using the same
    5.
    发明授权
    Bacteria and method for controlling plant disease using the same 有权
    用同样的方法控制植物病害的细菌和方法

    公开(公告)号：US08728459B2

    公开(公告)日：2014-05-20

    申请号：US12281560

    申请日：2007-03-02

    申请人： Tsuyoshi Isawa ,  Michiko Yasuda ,  Satoshi Shinozaki ,  Hideo Nakashita ,  Toshiaki Kudo

    发明人： Tsuyoshi Isawa ,  Michiko Yasuda ,  Satoshi Shinozaki ,  Hideo Nakashita ,  Toshiaki Kudo

    IPC分类号： A61K35/74 ,  A01H5/00 ,  C12N1/20 ,  A01N63/02

    CPC分类号： C12R1/01 ,  A01H17/00 ,  A01N63/00 ,  Y02A40/15

    摘要： An object of the present invention is to provide a means for imparting resistance against pathogenic fungal, pathogenic bacterial, or pathogenic viral disease to agriculturally useful plants. The present invention relates to a bacterium belonging to the genus Azospirillum or the genus Herbaspirillum capable of imparting resistance against pathogenic fungal, pathogenic bacterial, or pathogenic viral disease to a host plant by living symbiotically within the plant, a method for controlling plant disease using the bacteria, and plants produced by such method.

    摘要翻译： 本发明的一个目的是提供一种赋予农业上有用植物抗病原真菌，病原性细菌或病原性病毒抗性的方法。 本发明涉及属于Azospirillum属或Herbaspirillum属的细菌，其能够通过在植物内共生生物将宿主植物赋予致病性真菌，致病性细菌或病原性病毒病抗性，使用该方法控制植物病害 细菌和通过这种方法生产的植物。

    Phenoxyalkylamine derivatives useful as opioid δ receptor agonists
    6.
    发明授权
    Phenoxyalkylamine derivatives useful as opioid δ receptor agonists 失效
    用作阿片样物质δ受体激动剂的苯氧基烷基胺衍生物

    公开(公告)号：US06916822B2

    公开(公告)日：2005-07-12

    申请号：US10203617

    申请日：2001-02-16

    申请人： Masaki Tsushima ,  Kaori Tadauchi ,  Kenji Asai ,  Naoko Miike ,  Masako Imai ,  Toshiaki Kudo

    发明人： Masaki Tsushima ,  Kaori Tadauchi ,  Kenji Asai ,  Naoko Miike ,  Masako Imai ,  Toshiaki Kudo

    IPC分类号： A61K31/438 ,  A61K31/445 ,  A61K31/451 ,  A61K31/454 ,  A61K31/4709 ,  A61K31/517 ,  A61K31/536 ,  C07D211/14 ,  A61K31/5747 ,  C07D471/10 ,  A61K31/1438

    CPC分类号： C07D211/14 ,  A61K31/438 ,  A61K31/445 ,  A61K31/451 ,  A61K31/454 ,  A61K31/4709 ,  A61K31/517 ,  A61K31/536

    摘要： A medicament useful for preventive and/or therapeutic treatment of nerve system diseases which comprises, as an active ingredient, a compound represented by the following general formula (I) or a pharmacologically acceptable salt thereof: wherein, X represents a group represented by the following general formula (II), (III), (IV), (V), or (VI), “A” represents a saturated or unsaturated 3- to 6-membered carbocyclic group and the like, “B” represents CH2 and the like, “n” represents 0 to 2, R1 represents a hydrogen atom, a halogen atom and the like, R2, R3, and R7 to R14 represent a hydrogen atom, a lower alkyl group which may be substituted and the like, R4 represents a hydrogen atom, a lower alkyl group which may be substituted and the like, R5 represents a hydrogen atom, a halogen atom and the like, R6 represents a saturated or unsaturated monocyclic or bicyclic carbocyclic group and the like, and R5 and R6, R7 and R8, R9 and R10, or R11 and R12 may bind to each other to form a cyclic structure.

    摘要翻译： 用于预防和/或治疗神经系统疾病的药物，其包含作为活性成分的由以下通式（I）表示的化合物或其药理学上可接受的盐：其中，X表示下述 通式（II），（III），（IV），（V）或（VI）中，“A”表示饱和或不饱和的3至6元碳环基等，“B”表示CH 2 等，“n”表示0〜2，R 1表示氢原子，卤素原子等，R 2，R R 3和R 7相对于R 14代表氢原子，可被取代的低级烷基等，R“ 4表示氢原子，可被取代的低级烷基等，R 5表示氢原子，卤素原子等，R 6， SUP>表示饱和或不饱和的单环或双环碳环基团 R 5和R 6，R 7和R 8，R 9， R 10和R 10，或R 11和R 12可以彼此结合形成环状结构。

    Cephalosporin derivatives and antibiotics containing the same
    9.
    发明授权
    Cephalosporin derivatives and antibiotics containing the same 失效
    头孢菌素衍生物和含有相同的抗生素

    公开(公告)号：US4898858A

    公开(公告)日：1990-02-06

    申请号：US928955

    申请日：1986-11-10

    申请人： Seiji Shibahara ,  Tsuneo Okonogi ,  Yasushi Murai ,  Toshiaki Kudo ,  Takashi Yoshida ,  Ken Nishihata ,  Shinichi Kondo

    发明人： Seiji Shibahara ,  Tsuneo Okonogi ,  Yasushi Murai ,  Toshiaki Kudo ,  Takashi Yoshida ,  Ken Nishihata ,  Shinichi Kondo

    IPC分类号： A61K31/545 ,  A61K31/546 ,  A61P31/04 ,  C07D501/00 ,  C07D501/36

    CPC分类号： C07D501/00

    摘要： New cephalosporin derivatives of a general formula (I) and non-toxic salts and non-toxic esters thereof are provided: ##STR1## (wherein R represents an acyclic or cyclic lower alkyl group having 1-6 carbon atoms, which may optionally be substituted by a halogen atom; the steric configuration as asterisked (*) includes an optical-active (R)-form or (S)-form or an optical-inactive (RS)-form; n is 0 or 1, n.sup.1 is 0 to 3, n.sup.2 is 0 to 3; and when n.sup.1 is 0, n.sup.2 is 3; when n.sup.1 is 1, n.sup.2 is 2; when n.sup.1 is 2, n.sup.2 is 1; when n.sup.1 is 3, n.sup.2 is 0).The new derivatives of the formula (I) and non-toxic salts and esters thereof have high bactericidal activity with broad antibacterial spectra, and these are useful as active ingredients in bactericides.

    摘要翻译： 提供了通式（I）的新型头孢菌素衍生物及其无毒盐和无毒酯：其中R表示具有1-6个碳原子的无环或环状低级烷基 ，其可以任选地被卤素原子取代;星号（*）的空间构型包括光学活性（R）形式或（S）形式或光学非活性（RS）形式; n是0或 1，n1为0〜3，n2为0〜3，n2为0时，n2为3，n1为1时n2为2，n1为2时，n2为1，n1为3时，n2为0 ）。 式（I）的新衍生物及其无毒盐和酯具有广泛的抗菌谱具有高杀菌活性，可用作杀菌剂中的活性成分。