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公开(公告)号：US12055545B2
公开(公告)日：2024-08-06
申请号：US17717200
申请日：2022-04-11
发明人： Eran Eden , Kfir Oved , Assaf Cohen-Dotan , Roy Navon , Olga Boico , Meital Paz
IPC分类号： A61P31/04 , A61P31/12 , G01N33/50 , G01N33/535 , G01N33/547 , G01N33/569 , G01N33/68 , C07K14/52 , C07K14/525 , C07K14/54
CPC分类号： G01N33/56944 , A61P31/04 , A61P31/12 , G01N33/50 , G01N33/5005 , G01N33/535 , G01N33/547 , G01N33/56911 , G01N33/56983 , G01N33/6863 , G01N33/6869 , G01N33/6893 , G01N2333/521 , G01N2333/525 , G01N2333/5412 , G01N2333/5753 , G01N2333/70578 , G01N2333/70596 , G01N2333/715 , G01N2333/7151 , G01N2333/7155 , G01N2800/26 , G01N2800/60
摘要： Methods of determining infection type are disclosed. In one embodiment, the method comprises measuring the amount of TRAIL and/or IP10 no more than two days from symptom onset.
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公开(公告)号：US12044681B2
公开(公告)日：2024-07-23
申请号：US17372575
申请日：2021-07-12
发明人： Eran Eden , Kfir Oved , Assaf Cohen-Dotan , Roy Navon , Olga Boico , Gali Kronenfeld , Meital Paz , Ellen Bamberger
IPC分类号： C07K16/18 , C07K14/525 , C07K14/54 , C07K14/555 , C07K14/575 , C07K16/12 , C07K16/24 , C07K16/26 , C07K16/28 , G01N33/50 , G01N33/52 , G01N33/53 , G01N33/535 , G01N33/543 , G01N33/547 , G01N33/569 , G01N33/577 , G01N33/58 , G01N33/60 , G01N33/68 , G16B40/20 , G16B40/30 , G16B20/00 , G16B40/00
CPC分类号： G01N33/56911 , C07K14/525 , C07K14/5412 , C07K14/555 , C07K14/57527 , C07K16/12 , C07K16/18 , C07K16/241 , C07K16/248 , C07K16/249 , C07K16/26 , C07K16/2818 , C07K16/2875 , G01N33/5091 , G01N33/52 , G01N33/53 , G01N33/535 , G01N33/54306 , G01N33/547 , G01N33/577 , G01N33/581 , G01N33/582 , G01N33/60 , G01N33/6863 , G01N33/6869 , G01N33/6893 , G16B40/20 , G16B40/30 , G01N2333/525 , G01N2333/5412 , G01N2333/555 , G01N2333/5753 , G01N2333/585 , G01N2333/70578 , G01N2333/70596 , G01N2333/7155 , G01N2333/902 , G01N2333/916 , G01N2469/00 , G01N2800/122 , G01N2800/26 , G16B20/00 , G16B40/00
摘要： Methods of diagnosing infections are disclosed. In one embodiment, the method comprises measuring the amount of each of the polypeptides TRAIL, CRP, IP10 and at least one additional polypeptide selected from the group consisting of IL-6 and PCT.
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公开(公告)号：US11353456B2
公开(公告)日：2022-06-07
申请号：US16336528
申请日：2017-09-27
发明人： Kfir Oved , Eran Eden , Assaf Cohen-Dotan , Roy Navon , Niv Steven Mastboim , Olga Boico , Meital Paz
IPC分类号： A61B17/00 , G01N15/14 , G01N33/58 , G01N33/60 , G01N33/569 , G01N33/68 , G16H50/20 , C07K14/525
摘要： A method of measuring risk assessment in a patient with appendicitis is disclosed. The method comprises: (a) measuring the TRAIL protein level in a blood sample of the patient; (b) providing a risk assessment based on the TRAIL protein level.
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公开(公告)号：US20190120837A1
公开(公告)日：2019-04-25
申请号：US16238582
申请日：2019-01-03
发明人： Eran EDEN , Kfir Oved , Assaf Cohen-Dotan , Roy Navon , Olga Boico , Gali Kronenfeld , Meital Paz , Ellen Bamberger
IPC分类号： G01N33/569 , G01N33/577 , G01N33/535 , C07K16/12 , C07K16/24 , C07K16/26 , G01N33/52 , G01N33/547
摘要： Methods of diagnosing infections are disclosed. In one embodiment, the method comprises measuring the amount of each of the polypeptides TRAIL, CRP, IP10 and at least one additional polypeptide selected from the group consisting of IL-6 and PCT.
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公开(公告)号：US11340223B2
公开(公告)日：2022-05-24
申请号：US16316631
申请日：2017-07-10
发明人： Eran Eden , Kfir Oved , Assaf Cohen-Dotan , Roy Navon , Olga Boico , Meital Paz
IPC分类号： A61P31/04 , G01N33/535 , G01N33/547 , G01N33/569 , G01N33/68 , C07K14/525 , C07K14/54 , C07K14/57
摘要： Methods of determining infection type are disclosed. In one embodiment, the method comprises measuring the amount of TRAIL and/or IP10 no more than two days from symptom onset.
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公开(公告)号：USD888267S1
公开(公告)日：2020-06-23
申请号：US29645126
申请日：2018-04-24
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公开(公告)号：US20190237156A1
公开(公告)日：2019-08-01
申请号：US16355984
申请日：2019-03-18
发明人： Eran Eden , Kfir Oved , Roy Navon , Assaf Cohen-Dotan , Olga Boico
摘要： A method of analyzing biological data containing expression values of a plurality of polypeptides in the blood of a subject. The method comprises: calculating a distance between a segment of a curved line and an axis defined by a direction, the distance being calculated at a point over the curved line defined by a coordinate along the direction. The method further comprises correlating the distance to the presence of, absence of, or likelihood that the subject has, a bacterial infection. The coordinate is defined by a combination of the expression values, wherein at least 90% of the segment is between a lower bound line and an upper bound line.
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公开(公告)号：US12131807B2
公开(公告)日：2024-10-29
申请号：US18230718
申请日：2023-08-07
发明人： Eran Eden , Kfir Oved , Roy Navon , Assaf Cohen-Dotan , Olga Boico
IPC分类号： G16B5/20 , G06F17/18 , G16B5/00 , G16B20/00 , G16B20/20 , G16B25/10 , G16B40/00 , G16B40/20 , G16B40/30 , G16H50/50 , G01N33/569 , G16B25/00
CPC分类号： G16B5/20 , G06F17/18 , G16B5/00 , G16B20/00 , G16B20/20 , G16B25/10 , G16B40/00 , G16B40/20 , G16B40/30 , G16H50/50 , G01N33/56911 , G01N33/56983 , G16B25/00 , Y02A90/10
摘要： A method of analyzing biological data containing expression values of a plurality of polypeptides in the blood of a subject. The method comprises: calculating a distance between a segment of a curved line and an axis defined by a direction, the distance being calculated at a point over the curved line defined by a coordinate along the direction. The method further comprises correlating the distance to the presence of, absence of, or likelihood that the subject has, a bacterial infection. The coordinate is defined by a combination of the expression values, wherein at least 90% of the segment is between a lower bound line and an upper bound line.
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公开(公告)号：US11883825B2
公开(公告)日：2024-01-30
申请号：US16760546
申请日：2018-09-02
发明人： Noga Salomon , Kfir Oved , Yana Khalfin , Omer Nahum Katzenelson , Amir Gelman , Moran Brouk Rudich , Roy Navon , Assaf Cohen-Dotan , Eran Eden , Salit Tzaban , Arnon Zangvil , Ofer Halbreich , Matthew Fenwick , Adrian Charles Ian Scott-Murphy , Matthew Hou-Pou Yeung , James William Luther , Barbara Tornaghi , Andrea Besana , Thomas Sanelli Crugnale
CPC分类号： B01L3/50853 , G01N35/0098 , G01N35/0099 , G01N35/10 , A61B5/150022 , B01L2300/044 , B01L2400/06 , G01N2035/00851 , G01N2035/103
摘要： In a cartridge device for analyzing a body liquid, a first member of the cartridge has two or more wells for performing assays, and a second member of the cartridge has a compartment for holding one or more disposable pipette tips.
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公开(公告)号：US11776658B2
公开(公告)日：2023-10-03
申请号：US17875467
申请日：2022-07-28
发明人： Eran Eden , Kfir Oved , Roy Navon , Assaf Cohen-Dotan , Olga Boico
IPC分类号： G16B5/00 , G16B5/20 , G16B20/00 , G16B40/00 , G16B20/20 , G16B40/30 , G16B25/10 , G16B40/20 , G16H50/50 , G06F17/18 , G16B25/00 , G01N33/569
CPC分类号： G16B5/20 , G06F17/18 , G16B5/00 , G16B20/00 , G16B20/20 , G16B25/10 , G16B40/00 , G16B40/20 , G16B40/30 , G16H50/50 , G01N33/56911 , G01N33/56983 , G16B25/00 , Y02A90/10
摘要： A method of analyzing biological data containing expression values of a plurality of polypeptides in the blood of a subject. The method comprises: calculating a distance between a segment of a curved line and an axis defined by a direction, the distance being calculated at a point over the curved line defined by a coordinate along the direction. The method further comprises correlating the distance to the presence of, absence of, or likelihood that the subject has, a bacterial infection. The coordinate is defined by a combination of the expression values, wherein at least 90% of the segment is between a lower bound line and an upper bound line.
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