摘要:
A dryer for use with chemical compounds employs controlled vacuum, elevated temperature and dry, inert gas to dry the chemical compounds. The dryer includes a vacuum chamber into which trays containing the compounds are placed. The chamber includes heating elements which elevate the temperature of chemical samples placed within the chamber. Supplying and evacuating manifolds, each with a plurality of orifices for supplying and evacuating dry inert gas, provide a substantially laminar flow of dry inert gas just above the trays of chemical compounds which are to be dried. The laminar gas flow removes the unwanted vapor which tends to form above the tray of chemical compound, thus accelerating the drying process.
摘要:
A dryer for use with chemical compounds employs controlled vacuum, elevated temperature and dry, inert gas to dry the chemical compounds. The dryer includes a vacuum chamber into which trays containing the compounds are placed. The chamber includes heating elements which elevate the temperature of chemical samples placed within the chamber. Supplying and evacuating manifolds, each with a plurality of orifices for supplying and evacuating dry inert gas, provide a substantially laminar flow of dry inert gas just above the trays of chemical compounds which are to be dried. The laminar gas flow removes the unwanted vapor which tends to form above the tray of chemical compound, thus accelerating the drying process.
摘要:
A dryer for use with chemical compounds employs controlled vacuum, elevated temperature and dry, inert gas to dry the chemical compounds. The dryer includes a vacuum chamber into which trays containing the compounds are placed. The chamber includes heating elements which elevate the temperature of chemical samples placed within the chamber. Supplying and evacuating manifolds, each with a plurality of orifices for supplying and evacuating dry inert gas, provide a substantially laminar flow of dry inert gas just above the trays of chemical compounds which are to be dried. The laminar gas flow removes the unwanted vapor which tends to form above the tray of chemical compound, thus accelerating the drying process.
摘要:
A method for photoeluting photocleavable linker-attached chemical compounds, and an apparatus suitable for implementing the method, are disclosed. According to the method, photocleavable linker-attached library compounds are photoeluted from solid support media under conditions of controlled light exposure and controlled temperature. An apparatus suitable for carrying out the present photoelution method includes means for substantially evenly illuminating the photocleavable linker, means for controlling illumination time and intensity, and means for controlling sample temperature.
摘要:
A method for photoeluting photocleavable linker-attached chemical compounds, and an apparatus suitable for implementing the method, are disclosed. According to the method, photocleavable linker-attached library compounds are photoeluted from solid support media under conditions of controlled light exposure and controlled temperature. An apparatus suitable for carrying out the present photoelution method includes means for substantially evenly illuminating the photocleavable linker, means for controlling illumination time and intensity, and means for controlling sample temperature.
摘要:
A particle sorter/dispenser wherein particles that are suspended in a liquid are flowed through a conduit and selectively dispensed through a dispensing orifice. The conduit includes a sensing zone wherein the liquid-suspended particles are interrogated by a sensor. Data from the sensor is received by processing electronics that analyzes the data from the sensor and makes a decision whether or not to dispense a particle. The particle sorter/dispenser further includes a switch that, responsive to a signal from the processing electronics, controls whether or not a given particle is dispensed through the dispensing orifice. The switch has one or two valves that introduce relatively high-pressure liquid into the conduit. The flow streamlines of the high-pressure liquid controls the flow of the relatively low-pressure liquid-suspended particles in the conduit. Particles that are not dispensed are flowed past the dispensing orifice to a recycle reservoir that depends from the downstream end of the conduit.
摘要:
A universal fluid exchange device includes upper and lower reaction vessel supports which include pressure sealed injection and evacuation ports for each supported reaction vessel. Reaction vessels matingly engage through the injection and evacuation ports with fittings which are connected through flexible tubing to respective supplying and receiving vessels. The reaction vessels or fittings are moved into position, as required, so that reactants may be directly supplied from supplying vessels in the order and amount desired without operation of valves that can become contaminated, and so that the reaction vessels may dispel their contents into the appropriate receiving vessels. The system may be highly advantageous in applications such as combinatorial chemistry where myriad combinations of chemicals, solvents and reagents are employed.
摘要:
An apparatus for high-throughput analysis of compound absorption in a controlled environment that closely resembles in-vivo conditions. The apparatus includes at least one tissue-receiving enclosure that is capable of interfacing (e.g., via transfer of fluids, electronically, etc.) with a variety of preparative devices and analytical instrumentation. In some variations, the tissue-receiving enclosure is formed from two housings, which, when engaged, have a capsular shape. The enclosure receives a tissue sample in the form of an un-everted or everted intestinal segment or tubular artificial membrane. The tissue sample is coupled to a generally cylindrical tissue support. The tissue support and the enclosure are axially aligned, and openings at the ends of the enclosure align with openings at the ends of the tissue support. Two feed fittings, one for each end of the enclosure, forcefully mate with the aligned openings in the housing and the tissue support. The feed fitting seals against the ends of the tissue support, forming “outer” and “inner” chambers within the enclosure, with the intestinal tissue being the interface between the chambers. It is across this interface that absorption occurs.
摘要:
A multi-channel fluid dispenser includes a reservoir (106) with multiple internal chambers (844) with ports (850) to fill each chamber (844), a multi-channel liquid dispensing head, a plurality of fluid-delivery conduits, and support and positioning elements.
摘要:
A toilet bowl deodorizing, disinfecting and washing apparatus. In one variation, the apparatus includes a flexible enclosure that contains a bellows, a high-pressure reservoir, a liquid reservoir, and a plurality of nozzles. The bellows, liquid reservoir, and nozzles are selectively placed in fluid communication with the high-pressure reservoir. In use, the flexible enclosure is disposed beneath a toilet seat (or is itself a toilet seat). Deodorizing/disinfecting/washing liquid, which is contained in the liquid reservoir, is admitted to the high-pressure reservoir. When a person sits on the flexible enclosure, the bellows compresses air that is admitted to the high-pressure reservoir, thereby pressurizing the deodorizing/disinfecting/washing liquid that is contained therein. As the person gets off the flexible enclosure, the high-pressure reservoir is connected to the nozzles such that pressurized deodorizing/disinfecting/washing liquid is dispensed.