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1.Novel 27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 and 65577 molecules and uses therefor 失效
标题翻译: 小分子27877,18080,14081,32140,50352,16658,14223,16002,50566,65552和65577分子及其用途公开(公告)号:US20080234468A1
公开(公告)日:2008-09-25
申请号:US11981466
申请日:2007-10-31
申请人: Rachel E. Meyers , Joseph M. Carroll , William James Cook , Rosana Kapeller-Libermann , Nadine S. Weich , Rajasekhar Bandaru
发明人: Rachel E. Meyers , Joseph M. Carroll , William James Cook , Rosana Kapeller-Libermann , Nadine S. Weich , Rajasekhar Bandaru
IPC分类号: C07K14/00
CPC分类号: A61K38/16 , A01K2217/05 , A61K38/4813 , A61K39/00 , A61K2039/53 , C07K14/47 , C07K2319/00 , C12N9/0008 , C12N9/12 , C12N9/16 , C12N9/20 , C12N9/6416 , C12N9/6424 , C12N9/6491 , C12N9/93 , C12Q1/25 , C12Q1/37 , C12Q1/6883 , C12Q2600/156 , C12Q2600/158 , C12Y603/02019 , G01N33/5008 , G01N33/5011 , G01N33/502 , G01N33/573 , G01N33/68 , G01N2500/10 , Y10T436/143333 , A61K2300/00
摘要: The invention provides isolated nucleic acids molecules, designated 27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 and 65577 nucleic acid molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 and 65577 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 or 65577 gene has been introduced or disrupted. The invention still further provides isolated 27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 or 65577 proteins, fusion proteins, antigenic peptides and anti-27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 or 65577 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.
摘要翻译: 本发明提供分离的核酸分子,命名为27877,18080,14081,32140,50352,16658,14223,16002,50566,65552和65577核酸分子。 本发明还提供反义核酸分子,含有27877,18080,14081,32140,50502,16658,14223,16002,50566,65552和65577核酸分子的重组表达载体,已经引入表达载体的宿主细胞,以及 已经引入或破坏了27877,18080,14081,32140,50352,16658,14223,16002,50566,65552或65577基因的非人类转基因动物。 本发明还进一步提供分离的27877,18080,14081,32140,50352,16658,14223,16002,50566,65552或65577蛋白,融合蛋白,抗原肽和抗27877,18080,14081,32140,50352,16658,14223 ,16002,50566,65552或65577抗体。 还提供了利用本发明组合物的诊断和治疗方法。
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公开(公告)号:US07094587B2
公开(公告)日:2006-08-22
申请号:US10391364
申请日:2003-03-18
申请人: Rachel E. Meyers , Joseph M. Carroll , William James Cook , Rosana Kapeller-Libermann , Nadine S. Weich , Rajasekhar Bandaru
发明人: Rachel E. Meyers , Joseph M. Carroll , William James Cook , Rosana Kapeller-Libermann , Nadine S. Weich , Rajasekhar Bandaru
IPC分类号: C12N9/12
CPC分类号: A61K38/16 , A01K2217/05 , A61K38/4813 , A61K39/00 , A61K2039/53 , C07K14/47 , C07K2319/00 , C12N9/0008 , C12N9/12 , C12N9/16 , C12N9/20 , C12N9/6416 , C12N9/6424 , C12N9/6491 , C12N9/93 , C12Q1/25 , C12Q1/37 , C12Q1/6883 , C12Q2600/156 , C12Q2600/158 , C12Y603/02019 , G01N33/5008 , G01N33/5011 , G01N33/502 , G01N33/573 , G01N33/68 , G01N2500/10 , Y10T436/143333 , A61K2300/00
摘要: The invention provides isolated nucleic acids molecules, designated 16002 nucleic acid molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 16002 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 16002 gene has been introduced or disrupted. The invention still further provides isolated 16002 proteins, fusion proteins, antigenic peptides and anti-16002 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.
摘要翻译: 本发明提供了分离的核酸分子,命名为16002核酸分子。 本发明还提供反义核酸分子,含有16002个核酸分子的重组表达载体,其中引入了表达载体的宿主细胞,以及16002基因导入或破坏的非人转基因动物。 本发明还进一步提供了分离的16002蛋白,融合蛋白,抗原肽和抗-16002抗体。 还提供了利用本发明组合物的诊断和治疗方法。
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3.27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552, and 65577 molecules and uses therefor 失效
标题翻译: 27877,18080,14081,32140,50352,16658,14223,16002,50566,655552和65577分子及其用途公开(公告)号:US07351566B2
公开(公告)日:2008-04-01
申请号:US11429599
申请日:2006-05-05
申请人: Rachel E. Meyers , Joseph M. Carroll , William James Cook , Rosana Kapeller-Libermann , Nadine S. Weich , Rajasekhar Bandaru
发明人: Rachel E. Meyers , Joseph M. Carroll , William James Cook , Rosana Kapeller-Libermann , Nadine S. Weich , Rajasekhar Bandaru
CPC分类号: A61K38/16 , A01K2217/05 , A61K38/4813 , A61K39/00 , A61K2039/53 , C07K14/47 , C07K2319/00 , C12N9/0008 , C12N9/12 , C12N9/16 , C12N9/20 , C12N9/6416 , C12N9/6424 , C12N9/6491 , C12N9/93 , C12Q1/25 , C12Q1/37 , C12Q1/6883 , C12Q2600/156 , C12Q2600/158 , C12Y603/02019 , G01N33/5008 , G01N33/5011 , G01N33/502 , G01N33/573 , G01N33/68 , G01N2500/10 , Y10T436/143333 , A61K2300/00
摘要: The invention provides isolated nucleic acids molecules, designated 27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 and 65577 nucleic acid molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 and 65577 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 or 65577 gene has been introduced or disrupted. The invention still further provides isolated 27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 or 65577 proteins, fusion proteins, antigenic peptides and anti-27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 or 65577 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.
摘要翻译: 本发明提供分离的核酸分子,命名为27877,18080,14081,32140,50352,16658,14223,16002,50566,65552和65577核酸分子。 本发明还提供反义核酸分子,含有27877,18080,14081,32140,50502,16658,14223,16002,50566,65552和65577核酸分子的重组表达载体,已经引入表达载体的宿主细胞,以及 已经引入或破坏了27877,18080,14081,32140,50352,16658,14223,16002,50566,65552或65577基因的非人类转基因动物。 本发明还进一步提供分离的27877,18080,14081,32140,50352,16658,14223,16002,50566,65552或65577蛋白,融合蛋白,抗原肽和抗27877,18080,14081,32140,50352,16658,14223 ,16002,50566,65552或65577抗体。 还提供了利用本发明组合物的诊断和治疗方法。
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4.NOVEL 27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 AND 65577 MOLECULES AND USES THEREFOR 失效
标题翻译: 新颖的27877,18080,14081,32140,50352,16658,14223,16002,50566,655552和65577分子及其用途公开(公告)号:US20100098713A1
公开(公告)日:2010-04-22
申请号:US12559673
申请日:2009-09-15
申请人: Rachel E. Meyers , Joseph M. Carroll , William James Cook , Rosana Kapeller-Libermann , Nadine S. Welch , Rajasekhar Bandaru
发明人: Rachel E. Meyers , Joseph M. Carroll , William James Cook , Rosana Kapeller-Libermann , Nadine S. Welch , Rajasekhar Bandaru
IPC分类号: A61K39/395 , C07H21/00 , C12N1/00 , C12N5/00 , C07K14/00 , C07K16/00 , C12P21/00 , G01N33/53 , G01N33/48 , G01N33/68 , A61K38/02 , A61K38/16 , A61K31/7052 , A61P35/00 , A61P25/00 , A61P7/00 , A61P19/00 , A61P21/00 , A61P9/00
CPC分类号: A61K38/16 , A01K2217/05 , A61K38/4813 , A61K39/00 , A61K2039/53 , C07K14/47 , C07K2319/00 , C12N9/0008 , C12N9/12 , C12N9/16 , C12N9/20 , C12N9/6416 , C12N9/6424 , C12N9/6491 , C12N9/93 , C12Q1/25 , C12Q1/37 , C12Q1/6883 , C12Q2600/156 , C12Q2600/158 , C12Y603/02019 , G01N33/5008 , G01N33/5011 , G01N33/502 , G01N33/573 , G01N33/68 , G01N2500/10 , Y10T436/143333 , A61K2300/00
摘要: The invention provides isolated nucleic acids molecules, designated 27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 and 65577 nucleic acid molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 and 65577 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 or 65577 gene has been introduced or disrupted. The invention still further provides isolated 27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 or 65577 proteins, fusion proteins, antigenic peptides and anti-27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 or 65577 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.
摘要翻译: 本发明提供分离的核酸分子,命名为27877,18080,14081,32140,50352,16658,14223,16002,50566,65552和65577核酸分子。 本发明还提供反义核酸分子,含有27877,18080,14081,32140,50502,16658,14223,16002,50566,65552和65577核酸分子的重组表达载体,已经引入表达载体的宿主细胞,以及 已经引入或破坏了27877,18080,14081,32140,50352,16658,14223,16002,50566,65552或65577基因的非人类转基因动物。 本发明还进一步提供分离的27877,18080,14081,32140,50352,16658,14223,16002,50566,65552或65577蛋白,融合蛋白,抗原肽和抗27877,18080,14081,32140,50352,16658,14223 ,16002,50566,65552或65577抗体。 还提供了利用本发明组合物的诊断和治疗方法。
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5.26199, 33530, 33949, 47148, 50226, 58764, 62113, 32144, 32235, 23565, 13305, 14911, 86216, 25206, and 8843 molecules and uses therefor 有权
标题翻译: 26199,33530,3949,47148,50226,58764,612113,32144,32235,23565,13305,14911,86216,25206和8843分子及其用途公开(公告)号:US07485308B2
公开(公告)日:2009-02-03
申请号:US11493347
申请日:2006-07-26
申请人: Rachel E. Meyers , Kyle J. MacBeth , Rory A. J. Curtis , Laura A. Rudolph-Owen , Nadine S. Weich , Peter J. Olandt , Fong-Ying Tsai , Rosana Kapeller-Libermann , Joseph M. Carroll
发明人: Rachel E. Meyers , Kyle J. MacBeth , Rory A. J. Curtis , Laura A. Rudolph-Owen , Nadine S. Weich , Peter J. Olandt , Fong-Ying Tsai , Rosana Kapeller-Libermann , Joseph M. Carroll
CPC分类号: C12N9/001 , A01K2217/05 , A01K2217/075 , A61K38/00 , A61K48/00 , C07K2319/00 , C12N9/0006 , C12N9/10 , C12N9/1048 , C12N9/1096 , C12N9/12 , C12N9/1205 , C12N9/16 , C12N9/48 , C12N9/80 , C12N2799/021 , C12Q1/32 , G01N33/57407 , G01N33/57415 , G01N33/57419 , G01N33/57423 , G01N33/57449 , G01N2500/10 , Y10T436/143333
摘要: The invention provides isolated nucleic acids molecules, designated 26199, 33530, 33949, 47148, 50226, 58764, 62113, 32144, 32235, 23565, 13305, 14911, 86216, 25206 and 8843 nucleic acid molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 26199, 33530, 33949, 47148, 50226, 58764, 62113, 32144, 32235, 23565, 13305, 14911, 86216, 25206 and 8843 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 26199, 33530, 33949, 47148, 50226, 58764, 62113, 32144, 32235, 23565, 13305, 14911, 86216, 25206 or 8843 gene has been introduced or disrupted. The invention still further provides isolated 26199, 33530, 33949, 47148, 50226, 58764, 62113, 32144, 32235, 23565, 13305, 14911, 86216, 25206 or 8843 proteins, fusion proteins, antigenic peptides and anti-26199, 33530, 33949, 47148, 50226, 58764, 62113, 32144, 32235, 23565, 13305, 14911, 86216, 25206 or 8843 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.
摘要翻译: 本发明提供分离的核酸分子,命名为26199,33530,3399,47148,50226,58764,62113,32144,32235,23565,13305,14911,86216,25206和8843核酸分子。 本发明还提供反义核酸分子,包含26199,33530,3399,47148,50226,58764,62113,32144,32235,23565,13305,14911,86216,25206和8843核酸分子的重组表达载体,其中宿主细胞 已经引入了表达载体,并且已引入或破坏其中26199,33530,3399,47148,50216,58764,62113,32144,32235,23565,13305,14911,86216,25206或8843基因的非人转基因动物。 本发明还进一步提供了分离的26199,33530,3949,47148,50226,58764,62113,32144,32235,23565,13305,14911,86216,25206或8843蛋白,融合蛋白,抗原肽和抗-26199,33530,3399 ,47148,50226,58764,62113,32144,32235,23565,13305,14911,86216,25206或8843抗体。 还提供了利用本发明组合物的诊断和治疗方法。
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6.26199, 33530, 33949, 47148, 50226, 58764, 62113, 32144, 32235, 23565, 13305, 14911, 86216, 25206, and 8843 molecules and uses therefor 审中-公开
标题翻译: 26199,33530,3949,47148,50226,58764,612113,32144,32235,23565,13305,14911,86216,25206和8843分子及其用途公开(公告)号:US20100150901A1
公开(公告)日:2010-06-17
申请号:US12288677
申请日:2008-10-22
申请人: Rachel E. Meyers , Kyle J. MacBeth , Rory A.J. Curtis , Laura A. Rudolph-Owen , Nadine S. Weich , Peter J. Olandt , Fong-Ying Tsai , Rosana Kapeller-Libermann , Joseph M. Carroll
发明人: Rachel E. Meyers , Kyle J. MacBeth , Rory A.J. Curtis , Laura A. Rudolph-Owen , Nadine S. Weich , Peter J. Olandt , Fong-Ying Tsai , Rosana Kapeller-Libermann , Joseph M. Carroll
IPC分类号: A61K39/395 , C07H21/02 , C12N5/10 , C07K16/00 , C12P21/00 , G01N33/53 , C07H21/04 , C12Q1/68 , A61K38/00 , A61K38/16 , C07K14/00 , A61K31/7105 , A61K31/713 , A61K31/711 , A61P35/00
CPC分类号: C12N9/001 , A01K2217/05 , A01K2217/075 , A61K38/00 , A61K48/00 , C07K2319/00 , C12N9/0006 , C12N9/10 , C12N9/1048 , C12N9/1096 , C12N9/12 , C12N9/1205 , C12N9/16 , C12N9/48 , C12N9/80 , C12N2799/021 , C12Q1/32 , G01N33/57407 , G01N33/57415 , G01N33/57419 , G01N33/57423 , G01N33/57449 , G01N2500/10 , Y10T436/143333
摘要: The invention provides isolated nucleic acids molecules, designated 26199, 33530, 33949, 47148, 50226, 58764, 62113, 32144, 32235, 23565, 13305, 14911, 86216, 25206 and 8843 nucleic acid molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 26199, 33530, 33949, 47148, 50226, 58764, 62113, 32144, 32235, 23565, 13305, 14911, 86216, 25206 and 8843 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 26199, 33530, 33949, 47148, 50226, 58764, 62113, 32144, 32235, 23565, 13305, 14911, 86216, 25206 or 8843 gene has been introduced or disrupted. The invention still further provides isolated 26199, 33530, 33949, 47148, 50226, 58764, 62113, 32144, 32235, 23565, 13305, 14911, 86216, 25206 or 8843 proteins, fusion proteins, antigenic peptides and anti-26199, 33530, 33949, 47148, 50226, 58764, 62113, 32144, 32235, 23565, 13305, 14911, 86216, 25206 or 8843 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.
摘要翻译: 本发明提供分离的核酸分子,命名为26199,33530,3399,47148,50226,58764,62113,32144,32235,23565,13305,14911,86216,25206和8843核酸分子。 本发明还提供反义核酸分子,包含26199,33530,3399,47148,50226,58764,62113,32144,32235,23565,13305,14911,86216,25206和8843核酸分子的重组表达载体,其中宿主细胞 已经引入了表达载体,并且已引入或破坏其中26199,33530,3399,47148,50216,58764,62113,32144,32235,23565,13305,14911,86216,25206或8843基因的非人转基因动物。 本发明还进一步提供了分离的26199,33530,3949,47148,50226,58764,62113,32144,32235,23565,13305,14911,86216,25206或8843蛋白,融合蛋白,抗原肽和抗-26199,33530,3399 ,47148,50226,58764,62113,32144,32235,23565,13305,14911,86216,25206或8843抗体。 还提供了利用本发明组合物的诊断和治疗方法。
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7.21910, 56634, 55053, 2504, 15977, 14760, 25501, 17903, 3700, 21529, 26176, 26343, 56638, 18610, 33217, 21967, H1983, M1983, 38555 or 593 molecules and uses therefor 失效
标题翻译: 21910,5563,4505,2504,15977,14760,25501,17903,3720,21529,26176,26343,5666,18610,33217,26967,H1983,M1983,38555或593分子及其用途公开(公告)号:US07696316B2
公开(公告)日:2010-04-13
申请号:US11583766
申请日:2006-10-19
申请人: Rosana Kapeller-Libermann , John Joseph Hunter , Rachel E. Meyers , Laura A. Rudolph-Owen , Rory A. J. Curtis , Peter J. Olandt , Fong-Ying Tsai , Katherine M. Galvin , Miyoung Chun , Mark J. Williamson , Inmaculada Silos-Santiago , Rajasekhar Bandaru
发明人: Rosana Kapeller-Libermann , John Joseph Hunter , Rachel E. Meyers , Laura A. Rudolph-Owen , Rory A. J. Curtis , Peter J. Olandt , Fong-Ying Tsai , Katherine M. Galvin , Miyoung Chun , Mark J. Williamson , Inmaculada Silos-Santiago , Rajasekhar Bandaru
CPC分类号: C07K14/47 , A01K2217/05 , C12N9/1235
摘要: The invention provides isolated nucleic acids molecules, designated 21910, 56634, 55053, 2504, 15977, 14760, 25501, 17903, 3700, 21529, 26176, 26343, 56638, 18610, 33217, 21967, h1983, m1983, 38555 and 593 nucleic acid molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 21910, 56634, 55053, 2504, 15977, 14760, 25501, 17903, 3700, 21529, 26176, 26343, 56638, 18610, 33217, 21967, h1983, m1983, 38555 and 593 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 21910, 56634, 55053, 2504, 15977, 14760, 25501, 17903, 3700, 21529, 26176, 26343, 56638, 18610, 33217, 21967, h1983, m1983, 38555 or 593 gene has been introduced or disrupted. The invention still further provides isolated 21910, 56634, 55053, 2504, 15977, 14760, 25501, 17903, 3700, 21529, 26176, 26343, 56638, 18610, 33217, 21967, h1983, m1983, 38555 or 593 proteins, fusion proteins, antigenic peptides and anti-21910, 56634, 55053, 2504, 15977, 14760, 25501, 17903, 3700, 21529, 26176, 26343, 56638, 18610, 33217, 21967, h1983, m1983, 38555 or 593 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.
摘要翻译: 本发明提供分离的核酸分子,命名为21910,5663,55053,2504,15977,14760,25501,17903,3720,21529,26176,26343,5663,18610,33217,21967,h1983,m1983,38555和593核酸 分子。 本发明还提供反义核酸分子,含有21910,5663,55053,2504,15977,14760,25501,17903,3700,21529,26176,26343,5663,18610,33217,21967,h1983,m1983,3855的重组表达载体 和593个核酸分子,其中引入了表达载体的宿主细胞,以及非人类转基因动物,其中21910,5663,5553,2504,15977,14760,25501,17903,3720,21529,26176, 已经引入或破坏了18610,33217,21967,h1983,m1983,38555或593基因。 本发明还进一步提供分离的21910,5563,4560,25501,17903,3720,21529,26176,26343,5663,18610,33217,21967,h1983,m1983,38555或593蛋白,融合蛋白, 抗原肽和抗-19910,563634,55053,2504,15977,14760,25501,17903,3720,21529,26176,26343,56638,18610,33217,21967,h1983,m1983,38555或593抗体。 还提供了利用本发明组合物的诊断和治疗方法。
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8.Novel 13237, 18480, 2245, 16228, 7677, 26320, 46619, 33166, 16836, 46867, 21617, 55562, 39228, 62088, 46745, 23155, 21657, 42755, 32229, 22325, 46863 and 32252 molecules and uses therefor 失效
标题翻译: 小分子13237,18480,2245,16228,7677,26320,46169,36166,16836,46867,21617,55562,39228,62088,4675,23155,26657,42755,32229,22325,46863和32252分子及其用途公开(公告)号:US20090263860A1
公开(公告)日:2009-10-22
申请号:US11980299
申请日:2007-10-30
申请人: Rachel E. Meyers , Mark J. Williamson , Rosana Kapeller-Libermann , Kyle J. MacBeth , John Joseph Hunter , Laura A. Rudolph-Owen , Rajasekhar Bandaru , Fong-Ying Tsai
发明人: Rachel E. Meyers , Mark J. Williamson , Rosana Kapeller-Libermann , Kyle J. MacBeth , John Joseph Hunter , Laura A. Rudolph-Owen , Rajasekhar Bandaru , Fong-Ying Tsai
CPC分类号: C12N9/1205 , A01K2217/05 , A61K48/00 , C07K2319/00
摘要: The invention provides isolated nucleic acids molecules, designated 13237, 18480, 2245, 16228, 7677, 26320, 46619, 33166, 16836, 46867, 21617, 55562, 39228, 62088, 46745, 23155, 21657, 42755, 32229, 22325, 46863 and 32252 nucleic acid molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 13237, 18480, 2245, 16228, 7677, 26320, 46619, 33166, 16836, 46867, 21617, 55562, 39228, 62088, 46745, 23155, 21657, 42755, 32229, 22325, 46863 and 32252 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 13237, 18480, 2245, 16228, 7677, 26320, 46619, 33166, 16836, 46867, 21617, 55562, 39228, 62088, 46745, 23155, 21657, 42755, 32229, 22325, 46863 or 32252 gene has been introduced or disrupted. The invention still further provides isolated 13237, 18480, 2245, 16228, 7677, 26320, 46619, 33166, 16836, 46867, 21617, 55562, 39228, 62088, 46745, 23155, 21657, 42755, 32229, 22325, 46863 or 32252 proteins, fusion proteins, antigenic peptides and anti-13237, 18480, 2245, 16228, 7677, 26320, 46619, 33166, 16836, 46867, 21617, 55562, 39228, 62088, 46745, 23155, 21657, 42755, 32229, 22325, 46863 or 32252 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.
摘要翻译: 本发明提供分离的核酸分子,命名为13237,18480,2225,16228,7677,26320,4619,33166,16836,46867,21617,55562,39228,62088,46745,23155,21657,42755,32229,22325,46863 和32252个核酸分子。 本发明还提供反义核酸分子,重组表达载体,其含有13237,18480,2245,16228,7677,26320,4619,33166,16836,46867,21617,55562,39228,62088,46745,23155,216575,42755,32229 ,22325,46863和32252核酸分子,其中引入了表达载体的宿主细胞,以及非人类转基因动物,其中13237,18480,2362,46169,3677,26320,46869,38166,16836,46867,21617,26173,26169, 已经引入或破坏了55562,39228,62088,4675,23155,21657,42755,32229,22325,46863或32252基因。 本发明还进一步提供分离的13237,18480,2225,16228,7677,26320,4619,33166,16836,46867,21617,55562,39228,62088,46745,23155,21657,42755,32229,22325,46863或32252蛋白质 ,融合蛋白,抗原肽和抗-13237,18480,2225,16228,7677,26320,4619,33166,16836,46867,21617,55562,39228,62088,46745,23155,216547,42755,32229,22325,46863 或32252抗体。 还提供了利用本发明组合物的诊断和治疗方法。
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公开(公告)号:US20050214893A1
公开(公告)日:2005-09-29
申请号:US10968812
申请日:2004-10-19
申请人: Rachel Meyers , Rory Curtis , Maria Glucksmann , Rajasekhar Bandaru , Rosana Kapeller-Libermann
发明人: Rachel Meyers , Rory Curtis , Maria Glucksmann , Rajasekhar Bandaru , Rosana Kapeller-Libermann
IPC分类号: A61K38/00 , C07K14/47 , C07K14/705 , C12N9/02 , C12N9/10 , C12N9/48 , C12N9/90 , C12Q1/26 , G01N33/574
CPC分类号: C12N9/0004 , A61K38/00 , C07K14/47 , C07K14/4702 , C07K14/705 , C12N9/1048 , C12N9/48 , C12N9/90 , G01N33/57411 , G01N2500/04
摘要: The invention provides isolated nucleic acids molecules, designated 47476, 67210, 49875,46842,33201, 83378,84233,64708, 85041,84234,21617, 55562,23566,33489, and 57779 nucleic acid molecules, which encode novel human genes. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 47476, 67210, 49875, 46842, 33201, 83378, 84233, 64708, 85041, 84234, 21617, 55562, 23566, 33489, or 57779 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 47476, 67210, 49875, 46842, 33201, 83378, 84233, 64708, 85041, 84234, 21617, 55562, 23566, 33489, or 57779 gene has been introduced or disrupted. The invention still further provides isolated 47476, 67210, 49875, 46842, 33201, 83378, 84233, 64708, 85041, 84234, 21617, 55562, 23566, 33489, or 57779 proteins, fusion proteins, antigenic peptides and anti-47476, 67210, 49875, 46842, 33201, 83378, 84233, 64708, 85041, 84234, 21617, 55562, 23566, 33489, or 57779 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.
摘要翻译: 本发明提供编码新的人基因的分离的核酸分子,命名为47476,67210,49875,46842,33201,83378,84233,64708,85041,84234,21617,55562,23566,33489和57779核酸分子。 本发明还提供反义核酸分子,包含47476,67210,49875,4642,33201,83378,84233,64708,85041,84234,161617,55562,23566,33489或57779核酸分子的重组表达载体,宿主细胞 已经引入了表达载体的非人类转基因动物,以及引入了47476,67210,49875,4642,43708,85041,84234,16617,55562,23566,33489或57779基因的非人类转基因动物,或 中断了 本发明还进一步提供分离的47476,67210,49875,4642,33201,83378,84233,64708,85041,84234,21617,55562,23566,33489或57779号蛋白,融合蛋白,抗原肽和抗-47476,67210, 49875,4462,33201,83378,84233,66708,85041,84234,21617,55562,253566,33489或57779抗体。 还提供了利用本发明组合物的诊断方法。
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10.Novel 27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552, and 65577 molecules and uses therefor 失效
标题翻译: 新颖的27877,18080,14081,32140,50352,16658,14223,16002,50566,65552和65577分子及其用途公开(公告)号:US20060240464A1
公开(公告)日:2006-10-26
申请号:US11429599
申请日:2006-05-05
申请人: Rachel Meyers , Joseph Carroll , William Cook , Rosana Kapeller-Libermann , Nadine Weich , Rajasekhar Bandaru
发明人: Rachel Meyers , Joseph Carroll , William Cook , Rosana Kapeller-Libermann , Nadine Weich , Rajasekhar Bandaru
IPC分类号: C12Q1/68 , C07H21/04 , C12P21/06 , C07K14/705
CPC分类号: A61K38/16 , A01K2217/05 , A61K38/4813 , A61K39/00 , A61K2039/53 , C07K14/47 , C07K2319/00 , C12N9/0008 , C12N9/12 , C12N9/16 , C12N9/20 , C12N9/6416 , C12N9/6424 , C12N9/6491 , C12N9/93 , C12Q1/25 , C12Q1/37 , C12Q1/6883 , C12Q2600/156 , C12Q2600/158 , C12Y603/02019 , G01N33/5008 , G01N33/5011 , G01N33/502 , G01N33/573 , G01N33/68 , G01N2500/10 , Y10T436/143333 , A61K2300/00
摘要: The invention provides isolated nucleic acids molecules, designated 27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 and 65577 nucleic acid molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 and 65577 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 or 65577 gene has been introduced or disrupted. The invention still further provides isolated 27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 or 65577 proteins, fusion proteins, antigenic peptides and anti-27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 or 65577 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.
摘要翻译: 本发明提供分离的核酸分子,命名为27877,18080,14081,32140,50352,16658,14223,16002,50566,65552和65577核酸分子。 本发明还提供反义核酸分子,含有27877,18080,14081,32140,50502,16658,14223,16002,50566,65552和65577核酸分子的重组表达载体,已经引入表达载体的宿主细胞,以及 已经引入或破坏了27877,18080,14081,32140,50352,16658,14223,16002,50566,65552或65577基因的非人类转基因动物。 本发明还进一步提供分离的27877,18080,14081,32140,50352,16658,14223,16002,50566,65552或65577蛋白,融合蛋白,抗原肽和抗27877,18080,14081,32140,50352,16658,14223 ,16002,50566,65552或65577抗体。 还提供了利用本发明组合物的诊断和治疗方法。
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