专利检索 ap:("Reinhard Ebner" OR "Paul Young") AND inv:"Paul Young" 第 1 页

1.

发明申请
86 human secreted proteins 审中-公开
标题翻译： 86人分泌蛋白

公开(公告)号：US20050214844A1

公开(公告)日：2005-09-29

申请号：US11111953

申请日：2005-04-22

申请人： Paul Moore , Yanggu Shi , Craig Rosen , Steven Ruben , David Lafleur , Henrik Olsen , Reinhard Ebner , Laurie Brewer , Paul Young , John Greene , Ann Ferrie , Guo-Liang Yu , Jian Ni , Ping Feng

发明人： Paul Moore , Yanggu Shi , Craig Rosen , Steven Ruben , David Lafleur , Henrik Olsen , Reinhard Ebner , Laurie Brewer , Paul Young , John Greene , Ann Ferrie , Guo-Liang Yu , Jian Ni , Ping Feng

IPC分类号： G01N33/53 , A61K38/00 , A61K48/00 , A61P43/00 , C07H21/02 , C07H21/04 , C07K14/47 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/00 , C12N5/04 , C12N5/06 , C12N5/10 , C12N5/16 , C12N9/00 , C12N15/00 , C12N15/09 , C12N15/10 , C12N15/11 , C12N15/12 , C12P21/02 , C12P21/04 , C12P21/06 , C12Q1/68 , G01N33/566

CPC分类号： C07K14/47

摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.

摘要翻译： 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的病症的诊断和治疗方法。

2.

发明申请
Cancer-linked genes as targets for chemotherapy 审中-公开
标题翻译：癌症相关基因为化疗靶向

公开(公告)号：US20080025981A1

公开(公告)日：2008-01-31

申请号：US11599845

申请日：2006-11-15

申请人： Paul Young , Reinhard Ebner , Zoe Weaver , Jeffrey Strovel , Stephen Horrigan , Martin Shea , Bernd Weigle , Michael Rieger , Jennifer Rick , Colyn Cain

发明人： Paul Young , Reinhard Ebner , Zoe Weaver , Jeffrey Strovel , Stephen Horrigan , Martin Shea , Bernd Weigle , Michael Rieger , Jennifer Rick , Colyn Cain

IPC分类号： A61K39/395 , A61P35/00 , C07K16/30 , C12Q1/68

CPC分类号： G01N33/5011 , C12Q1/6886 , C12Q2600/136 , C12Q2600/158

摘要： Cancer-linked gene sequences, and derived amino acid sequences, are disclosed along with methods for assaying for potential antitumor agents based on their modulation of the expression of these cancer-related genes. Also disclosed are antibodies that react with the disclosed polypeptides and methods of using the antibodies to treat cancerous conditions, such as using the antibody to target cancerous cells in vivo for purposes of delivering therapeutic agents thereto. Also described are methods of diagnosing cancer using the gene sequences as well as the polypeptide sequences.

摘要翻译： 公开了与癌基因序列和衍生的氨基酸序列，以及基于它们对这些癌症相关基因表达的调节来测定潜在的抗肿瘤剂的方法。还公开了与所公开的多肽反应的抗体以及使用抗体治疗癌性病症的方法，例如使用抗体靶向靶细胞体内的癌细胞用于递送治疗剂的目的。还描述了使用基因序列以及多肽序列诊断癌症的方法。

3.

发明申请
186 human secreted proteins 审中-公开

公开(公告)号：US20060084082A1

公开(公告)日：2006-04-20

申请号：US11144947

申请日：2005-06-06

申请人： Steven Ruben , Craig Rosen , Daniel Soppet , Kenneth Carter , Daniel Bednarik , Gregory Endress , Guo-Liang Yu , Jian Ni , Ping Feng , Paul Young , John Greene , Ann Ferrie , D. Duan , Jing-Shan Hu , Kimberly Florence , Henrik Olsen , Carrie Fischer , Reinhard Ebner , Laurie Brewer , Paul Moore , Yanggu Shi , David LaFleur , Yi Li , ZhiZhen Zeng , Hla Kyaw

发明人： Steven Ruben , Craig Rosen , Daniel Soppet , Kenneth Carter , Daniel Bednarik , Gregory Endress , Guo-Liang Yu , Jian Ni , Ping Feng , Paul Young , John Greene , Ann Ferrie , D. Duan , Jing-Shan Hu , Kimberly Florence , Henrik Olsen , Carrie Fischer , Reinhard Ebner , Laurie Brewer , Paul Moore , Yanggu Shi , David LaFleur , Yi Li , ZhiZhen Zeng , Hla Kyaw

IPC分类号： C12Q1/68 , C07H21/04 , C12P21/06 , C12N9/00

CPC分类号： C07K14/4748 , A61K38/00 , C07K14/47 , G01N33/566 , G01N2800/00

摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.

4.

发明申请
90 human secreted proteins 审中-公开
标题翻译： 90种人体分泌的蛋白质

公开(公告)号：US20050244845A1

公开(公告)日：2005-11-03

申请号：US10986501

申请日：2004-11-12

申请人： Steven Ruben , Daniel Soppet , Reinhard Ebner , Henrik Olsen , Paul Young , John Greene , Ann Ferrie , Guo-Liang Yu , Jian Ni , Craig Rosen , Laurie Brewer , Fouad Janat , Charles Birse

发明人： Steven Ruben , Daniel Soppet , Reinhard Ebner , Henrik Olsen , Paul Young , John Greene , Ann Ferrie , Guo-Liang Yu , Jian Ni , Craig Rosen , Laurie Brewer , Fouad Janat , Charles Birse

IPC分类号： C07H21/04 , C07K14/47 , C12N9/00 , C12N15/09 , C12Q1/68

CPC分类号： C07K14/47 , C12Q1/6883

摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.

摘要翻译： 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的疾病，病症和/或病症的诊断和治疗方法。

5.

发明申请
27 human secreted proteins 审中-公开
标题翻译： 27种人体分泌的蛋白质

公开(公告)号：US20050239099A1

公开(公告)日：2005-10-27

申请号：US10963903

申请日：2004-10-14

申请人： Steven Ruben , Jian Ni , Reinhard Ebner , Craig Rosen , Yanggu Shi , Charles Birse , Kimberly Florence , George Komatsoulis , David LaFleur , Paul Moore , Henrik Olsen , Paul Young

发明人： Steven Ruben , Jian Ni , Reinhard Ebner , Craig Rosen , Yanggu Shi , Charles Birse , Kimberly Florence , George Komatsoulis , David LaFleur , Paul Moore , Henrik Olsen , Paul Young

IPC分类号： G01N33/50 , A61K31/711 , A61K38/00 , A61K48/00 , A61P9/00 , A61P17/00 , A61P19/02 , A61P25/02 , A61P25/16 , A61P25/18 , A61P25/22 , A61P25/24 , A61P25/28 , A61P27/02 , A61P29/00 , A61P31/04 , A61P31/12 , A61P35/00 , A61P37/00 , A61P43/00 , C07H21/04 , C07K14/47 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/00 , C12N15/09 , C12P21/02 , C12Q1/00 , C12Q1/02 , C12Q1/68 , C12Q1/6883 , G01N33/15 , G01N33/53 , G01N33/566

CPC分类号： C07K14/47 , C12Q1/00 , C12Q1/6883

摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.

摘要翻译： 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的疾病，病症和/或病症的诊断和治疗方法。

6.

发明申请
70 Human Secreted Proteins 审中-公开
标题翻译： 70人类分泌蛋白

公开(公告)号：US20070238664A1

公开(公告)日：2007-10-11

申请号：US11751886

申请日：2007-05-22

申请人： Steven Ruben , Craig Rosen , Carrie Fischer , Daniel Soppet , Kenneth Carter , Daniel Bednarik , Gregory Endress , Guo-Liang Yu , Jian Ni , Ping Feng , Paul Young , John Greene , Ann Ferrie , Roxanne Duan , Jing-Shan Hu , Kimberly Florence , Henrik Olsen , Reinhard Ebner , Laurie Brewer , Yanggu Shi

发明人： Steven Ruben , Craig Rosen , Carrie Fischer , Daniel Soppet , Kenneth Carter , Daniel Bednarik , Gregory Endress , Guo-Liang Yu , Jian Ni , Ping Feng , Paul Young , John Greene , Ann Ferrie , Roxanne Duan , Jing-Shan Hu , Kimberly Florence , Henrik Olsen , Reinhard Ebner , Laurie Brewer , Yanggu Shi

IPC分类号： C07K14/47 , A61K38/00 , C07H21/04 , C12N15/63 , G01N33/53 , G01N33/48 , C07K16/00 , C07K1/00

CPC分类号： C07K14/47 , Y10T436/143333

摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.

摘要翻译： 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的病症的诊断和治疗方法。

7.

发明申请
ANTIBODIES TO HHPEN62 POLYPEPTIDE 失效
标题翻译： HHPEN62多肽的抗体

公开(公告)号：US20070172830A1

公开(公告)日：2007-07-26

申请号：US10849979

申请日：2004-05-21

申请人： Steven Ruben , Kimberly Florence , Jian Ni , Craig Rosen , Kenneth Carter , Paul Moore , Henrik Olsen , Yanggu Shi , Paul Young , Ying-Fei Wei , Laurie Brewer , Daniel Soppet , David LaFleur , Gregory Endress , Reinhard Ebner , Charles Birse

发明人： Steven Ruben , Kimberly Florence , Jian Ni , Craig Rosen , Kenneth Carter , Paul Moore , Henrik Olsen , Yanggu Shi , Paul Young , Ying-Fei Wei , Laurie Brewer , Daniel Soppet , David LaFleur , Gregory Endress , Reinhard Ebner , Charles Birse

IPC分类号： C12Q1/68 , A61K48/00 , A61K38/17 , C07K14/47 , C12P21/06

CPC分类号： C07K14/47

摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.

摘要翻译： 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的疾病，病症和/或病症的诊断和治疗方法。

8.

发明申请
Cancer-linked gene as target for chemotherapy 审中-公开

公开(公告)号：US20060099214A1

公开(公告)日：2006-05-11

申请号：US10518039

申请日：2003-06-10

申请人： Reinhard Ebner , Paul Young

发明人： Reinhard Ebner , Paul Young

IPC分类号： A61K39/395 , C12Q1/68 , G01N33/574 , G06F19/00 , C07H21/04 , C12P21/06 , C07K16/46 , C07K16/30 , C07K14/82

CPC分类号： C12Q1/6886 , A61K2039/505 , C07K14/4748 , C12Q2600/136 , C12Q2600/16 , G01N33/5011 , G01N33/5023

摘要： Cancer-linked gene sequences, and derived amino acid sequences, are disclosed along with processes for assaying potential antitumor agents based on their modulation of the expression of these cancer-linked genes. Also disclosed are antibodies that react with the disclosed polypeptides and methods of using the antibodies to treat cancerous conditions, such as by using the antibody to target cancerous cells in vivo for purposes of delivering therapeutic agents thereto. Also described are methods of diagnosing using the gene sequences.