公开(公告)号：US5736100A

公开(公告)日：1998-04-07

申请号：US531199

申请日：1995-09-19

申请人： Ryo Miyake ,  Koichi Tsuzuki ,  Isao Yamazaki ,  Hideo Enoki ,  Hiroshi Mitsumaki

发明人： Ryo Miyake ,  Koichi Tsuzuki ,  Isao Yamazaki ,  Hideo Enoki ,  Hiroshi Mitsumaki

IPC分类号： B01F11/02 ,  B06B3/00 ,  G01N35/00 ,  G01N35/02 ,  G01N37/00

CPC分类号： B01F11/0283 ,  B06B3/00 ,  G01N35/025 ,  G01N2035/00554 ,  Y10T436/11 ,  Y10T436/113332 ,  Y10T436/25

摘要： A chemical analyzer has turn tables respectively carrying reaction vessels, sample containers and reagent containers disposed thereon in circular rows. A sample pipetting mechanism and a reagent pipetting mechanism are provided to transfer predetermined amounts of sample and reagent solution from a sample container and from a reagent container into a reaction vessel. The thus transferred sample and reagent solution are mixed in the reaction vessel by a stirrer comprising a piezoelectric element which is disposed in non-contacting relationship to the sample and reagent solution in the reaction vessel and is electrically energized to generate a sound wave which causes a circulating flow of the reagent solution in the reaction vessel whereby the sample and the reagent solution are mixed in a non-invasive manner.

摘要翻译： 化学分析仪具有分别承载设置在其上的反应容器，样品容器和试剂容器的转台。 提供样品移液机构和试剂吸移机构，以将预定量的样品和试剂溶液从样品容器和试剂容器转移到反应容器中。 将这样转移的样品和试剂溶液通过搅拌器混合在反应容器中，所述搅拌器包括与反应容器中的样品和试剂溶液非接触关系设置的压电元件，并且被电通电以产生声波， 在反应容器中循环流动试剂溶液，由此将样品和试剂溶液以非侵入性的方式混合。

公开(公告)号：US5519635A

公开(公告)日：1996-05-21

申请号：US301028

申请日：1994-09-06

申请人： Ryo Miyake ,  Masaharu Ishii ,  Hideo Enoki ,  Isao Yamazaki ,  Kazumichi Imai ,  Tadafumi Kuroishi ,  Yu-ming Hsueh

发明人： Ryo Miyake ,  Masaharu Ishii ,  Hideo Enoki ,  Isao Yamazaki ,  Kazumichi Imai ,  Tadafumi Kuroishi ,  Yu-ming Hsueh

IPC分类号： G01N1/00 ,  B01L3/00 ,  B01L9/00 ,  G01N30/02 ,  G01N30/34 ,  G01N30/60 ,  G01N30/86 ,  G01N30/88 ,  G01N35/00 ,  G01N35/08 ,  G01N37/00 ,  G01N35/10

CPC分类号： B01F13/0059 ,  B01F5/0475 ,  B01F5/0485 ,  B01L3/502715 ,  B01L9/527 ,  G01N30/88 ,  G01N35/085 ,  B01L2200/027 ,  B01L2200/028 ,  B01L2200/10 ,  B01L2200/143 ,  B01L2300/0816 ,  B01L2300/0867 ,  B01L2400/0487 ,  B01L3/0268 ,  B01L3/502753 ,  G01N2030/027 ,  G01N2030/8881 ,  G01N2035/00326 ,  G01N30/60 ,  G01N30/6095 ,  Y10T436/11 ,  Y10T436/25375 ,  Y10T436/2575

摘要： In order to provide an apparatus for chemical analysis capable of eliminating time consuming changing connections of flow paths and analytical elements, and of operating for analysis without any special knowledge, the apparatus for chemical analysis comprises a main body of analytical apparatus provided with sampling device for sucking sample, liquid controller for transferring the sucked sample and reagents, and detector for measuring the sample, and analytical unit provided with a liquid connector and a signal connector for connecting to the main body of analytical apparatus, and memory storing at least analytical method, and analysis of the sample is performed by attaching and fixing the analytical unit to said main body of analytical apparatus, transferring at least analytical method stored in the memory to the main body of analytical apparatus, and analyzing the sample in accordance the said analytical method.

摘要翻译： 为了提供一种用于化学分析的设备，其能够消除流路和分析元件的耗时变化的连接以及在没有任何特殊知识的情况下进行分析的操作，所述用于化学分析的装置包括分析装置的主体，其具有采样装置 吸取样品，用于转移吸取的样品和试剂的液体控制器和用于测量样品的检测器;以及分析单元，其具有连接到分析装置的主体的液体连接器和信号连接器，以及至少存储至少分析方法的存储器， 通过将分析单元附着并固定在分析装置的主体上，至少将存储在存储器中的分析方法转移到分析装置的主体，并根据所述分析方法分析样品来进行样品的分析。

公开(公告)号：US06197255B1

公开(公告)日：2001-03-06

申请号：US09398046

申请日：1999-09-17

申请人： Ryo Miyake ,  Yoshihiro Nagaoka ,  Akira Koide ,  Naruo Watanabe ,  Yasuhiko Sasaki ,  Hajime Kato ,  Takao Terayama ,  Hiroshi Mitsumaki ,  Hiroyasu Uchida ,  Takeshi Shibuya ,  Yasuhiro Yoshimura

发明人： Ryo Miyake ,  Yoshihiro Nagaoka ,  Akira Koide ,  Naruo Watanabe ,  Yasuhiko Sasaki ,  Hajime Kato ,  Takao Terayama ,  Hiroshi Mitsumaki ,  Hiroyasu Uchida ,  Takeshi Shibuya ,  Yasuhiro Yoshimura

IPC分类号： G01N3502

CPC分类号： G01N35/00663 ,  B01F11/0283 ,  G01N35/025 ,  G01N2035/00673 ,  Y10T436/11 ,  Y10T436/113332 ,  Y10T436/114998 ,  Y10T436/119163 ,  Y10T436/2575

摘要： A chemical analyzing apparatus comprises a reaction cell holder which holds a plurality of reaction cells that are supplied with samples and reagents at a predetermined position, a measurer for measuring characteristics of the sample, a plurality of reagent containers, a liquid deliverer provided below each of the plurality of reagent containers, one or more sound wave generators provided outside the reaction cells, and storage containers for storing cleansing liquid with different contamination states. The cleansing liquid with different contamination states is reused according to the contamination levels of the reaction cells.

摘要翻译： 化学分析装置包括：反应池保持器，其保持在预定位置处供给样品和试剂的多个反应池，用于测量样品特性的测量器，多个试剂容器，下方设置的液体输送器 多个试剂容器，设置在反应室外的一个或多个声波发生器和用于存储具有不同污染状态的清洁液的储存容器。 具有不同污染状态的清洁液体根据反应池的污染水平重新使用。

公开(公告)号：US06290908B1

公开(公告)日：2001-09-18

申请号：US09281098

申请日：1999-03-29

申请人： Masao Fukunaga ,  Tamio Ishihara ,  Koji Saito ,  Katsutoshi Yamada ,  Hideo Enoki ,  Sadao Mori ,  Ryo Miyake ,  Takao Terayama ,  Masatoshi Kanamaru

发明人： Masao Fukunaga ,  Tamio Ishihara ,  Koji Saito ,  Katsutoshi Yamada ,  Hideo Enoki ,  Sadao Mori ,  Ryo Miyake ,  Takao Terayama ,  Masatoshi Kanamaru

IPC分类号： G01N1500

CPC分类号： C02F1/008 ,  C02F2103/02 ,  C02F2201/008 ,  C02F2201/009 ,  C02F2209/11 ,  C02F2209/29 ,  C02F2209/40 ,  G01N33/1893 ,  Y02A20/212

摘要： A water quality meter is composed of a plurality of analyzing units for analyzing water samples introduced from a water distribution pipe, each analyzing unit including a reagent mixing cell and a measuring cell, and a liquid introducing unit integrated with the analyzing units, which is composed of a single member in which a plurality of fluid flow paths for feeding various types of liquid including the water sample into the analyzing unit are formed. Furthermore, the cells and the plurality of three-dimensional fluid flow paths formed in the single member are fabricated by a micro-fabrication technique using photo-curing resin.

摘要翻译： 水质计由多个用于分析从配水管引入的水样的分析单元构成，每个分析单元包括试剂混合室和测量池，以及与分析单元一体化的液体导入单元，其组成 其中形成有用于将包括水样本的各种类型的液体供给到分析单元中的多个流体流路的单个构件。 此外，通过使用光固化树脂的微制造技术来制造在单个构件中形成的电池和多个三维流体流动路径。

公开(公告)号：US06852282B2

公开(公告)日：2005-02-08

申请号：US10121734

申请日：2002-04-15

申请人： Ryo Miyake ,  Naruo Watanabe ,  Hajime Katou ,  Takao Terayama ,  Yasushi Nomura ,  Hiroshi Mitsumaki

发明人： Ryo Miyake ,  Naruo Watanabe ,  Hajime Katou ,  Takao Terayama ,  Yasushi Nomura ,  Hiroshi Mitsumaki

IPC分类号： G01N35/04 ,  G01N35/00 ,  G01N35/02 ,  G01N35/10

CPC分类号： G01N35/1002 ,  G01N35/0099 ,  G01N35/028 ,  Y10T436/2575

摘要： A chemical analyzer for measuring a concentration of components of a sample liquid, by mixing the sample liquid with reagents, so as to react the reagents upon the components thereof, includes a carrier having an introducing portion through which the sample liquid is injected, passages for distributing the sample liquid injected from the introducing portion, and plural reactor portions which hold the sample liquid therein to be mixed with the reagent, thereby to react. A movable driver portion is provided on which the carrier is mounted and a reagent charging device is provided for ejecting the reagents which are different for the respective plural reactor portions of the carrier, sequentially. Further, a detector is provided for detecting the components after mixing the reagents with the sample liquid.

摘要翻译： 一种用于测量样品液体组分浓度的化学分析仪，通过将样品液体与试剂混合以使试剂与其组分反应，包括具有引入部分的载体，通过该引入部分注入样品液体，通道用于 分配从引入部分注入的样品液体，以及将样品液体保持在其中以与试剂混合的多个反应器部分，从而进行反应。 提供了可移动的驱动器部分，其上安装有载体，并且提供了试剂充电装置，用于顺序地喷射对于载体的各个反应器部分不同的试剂。 此外，提供了一种用于在将试剂与样品液体混合之后检测组分的检测器。

公开(公告)号：US06599477B1

公开(公告)日：2003-07-29

申请号：US09136070

申请日：1998-08-19

申请人： Ryo Miyake ,  Akira Koide ,  Takeo Takagi ,  Takao Terayama ,  Yasushi Nomura ,  Hiroshi Mitsumaki

发明人： Ryo Miyake ,  Akira Koide ,  Takeo Takagi ,  Takao Terayama ,  Yasushi Nomura ,  Hiroshi Mitsumaki

IPC分类号： G01N3504

CPC分类号： G01N35/1002 ,  F04B43/043 ,  G01N35/025 ,  G01N35/1016 ,  Y10T436/11 ,  Y10T436/113332 ,  Y10T436/114998 ,  Y10T436/119163 ,  Y10T436/2575

摘要： A chemically analyzing apparatus includes a plurality of reaction containers, a reaction container holder for holding the plurality of reaction containers and for supplying a sample and reagent at predetermined positions, a plurality of reagent containers for holding reagent adapted to be supplied into the reaction containers, a reagent container holder provided above the reaction container holder, for holding the plurality of reagent containers, a measuring part for measuring physical properties of the sample, a liquid feed mechanism provided in a lower part of each of the plurality of reagent containers, for supplying a predetermined quantity of reagent from each of the reagent container into the associated reaction containers by means of the liquid feed mechanism. With this arrangement, it is possible to provide a chemically analyzing apparatus incorporating a reagent supply mechanism which can prevent reagent from being uselessly consumed, which does not substantially require washing liquid, which does not require periodical disassembly and washing, and which can easily change the feed quantity of reagent.

摘要翻译： 化学分析装置包括多个反应容器，用于保持多个反应容器并用于在预定位置供应样品和试剂的反应容器保持器，用于保持适于供应到反应容器中的试剂的多个试剂容器， 设置在反应容器保持器上方的用于保持多个试剂容器的试剂容器保持器，用于测量样品的物理性质的测量部件，设置在多个试剂容器的每个的下部的液体供给机构，用于供给 通过液体供给机构将来自每个试剂容器的预定量的试剂输送到相关联的反应容器中。 通过这种布置，可以提供一种化学分析装置，其包括试剂供给机构，该试剂供给机构能够防止不需要定期拆卸和洗涤的基本上不需要洗涤液的试剂被无用地消耗，并且可以容易地改变 试剂的供料量。

公开(公告)号：US06193933B1

公开(公告)日：2001-02-27

申请号：US09179090

申请日：1998-10-27

申请人： Yasuhiko Sasaki ,  Ryo Miyake ,  Akira Koide ,  Takao Terayama ,  Hiroshi Mitsumaki ,  Hiroyasu Uchida

发明人： Yasuhiko Sasaki ,  Ryo Miyake ,  Akira Koide ,  Takao Terayama ,  Hiroshi Mitsumaki ,  Hiroyasu Uchida

IPC分类号： G01N3500

CPC分类号： G01N35/00663 ,  G01N35/1002 ,  G01N2035/00673 ,  Y10T436/11 ,  Y10T436/111666 ,  Y10T436/113332 ,  Y10T436/114998 ,  Y10T436/119163 ,  Y10T436/2575

摘要： Heretofore, there has been demanded an automatic analysis apparatus which can prevent cross-contamination between reagents, which can prevent dust and gas from entering a reagent supply device, which can always know a remaining quantity of the reagent while can reduce the quantity of waste. According to the present invention, there is provided an automatic analysis apparatus in which a reagent supply device for supplying a reagent from a reagent container into a reaction container is removably attached to the reagent container, a protective door is provided in the reagent supply port in order to aim at preventing dust from entering the reagent supply device, and further the reagent container and the reagent supply device are provided with recording mediums for recording therein conditions thereof, a time of replacement thereof or the like, and which can inform whether the setting is proper or not.

摘要翻译： 迄今为止，已经要求能够防止试剂之间的交叉污染的自动分析装置，其可以防止灰尘和气体进入试剂供应装置，这可以总是知道试剂的剩余量，同时可以减少废物的量。 根据本发明，提供了一种自动分析装置，其中用于将试剂从试剂容器供给到反应容器中的试剂供应装置可移除地附接到试剂容器，在试剂供应口中设置有保护门 为了防止灰尘进入试剂供应装置，进一步地，试剂容器和试剂供应装置设置有用于在其中记录条件的记录介质，其更换时间等，并且可以通知设置 是否适用

公开(公告)号：US07204961B2

公开(公告)日：2007-04-17

申请号：US09259306

申请日：1999-03-01

申请人： Akira Koide ,  Ryo Miyake ,  Takao Terayama ,  Hiroshi Mitsumaki ,  Tomonari Morioka

发明人： Akira Koide ,  Ryo Miyake ,  Takao Terayama ,  Hiroshi Mitsumaki ,  Tomonari Morioka

IPC分类号： B01L3/02 ,  G01N1/10 ,  F04B23/06 ,  F16K16/00 ,  F16K7/07

CPC分类号： F04B43/043 ,  F04B53/1042 ,  Y10T137/87788 ,  Y10T137/87893 ,  Y10T436/2575

摘要： Provided is a liquid feed apparatus for feeding liquid by operating a diaphragm at a high frequency, in which an inlet valve and an outlet valve are integrally incorporated with a liquid feed chamber, the positions of the valve are shifted into peripheral parts of the liquid feed chamber so as to allow fluid to smoothly flow from the inlet to the outlet in order to prevent air bubbles from causing pressure fluctuation during liquid feed, from remaining in the liquid feed chamber. Further, the valve has a center beam structure in which a protrusion having a height greater than several micron meters, is formed in the seat part of the valve so as to deform a center beam for pressurizing the valve in order to enhance the shut-off ability of the valve, and the center beam has a small surface area in the direction of displacement of the valve.

摘要翻译： 本发明提供一种液体供给装置，其通过以高频操作隔膜，其中入口阀和出口阀与液体供给室一体地结合在一起，阀的位置移动到液体进料的周边部分 以允许流体从入口到出口平滑地流动，以防止气泡在液体进料期间引起压力波动，从而保留在液体进料室中。 此外，阀具有中心梁结构，其中高度大于几微米的突起形成在阀的阀座部分中，以便使用于加压阀的中心梁变形，以便增强切断 阀的能力和中心梁在阀的位移方向上具有小的表面积。

公开(公告)号：US06383452B1

公开(公告)日：2002-05-07

申请号：US09526565

申请日：2000-03-16

申请人： Ryo Miyake ,  Naruo Watanabe ,  Hajime Katou ,  Takao Terayama ,  Yasushi Nomura ,  Hiroshi Mitsumaki

发明人： Ryo Miyake ,  Naruo Watanabe ,  Hajime Katou ,  Takao Terayama ,  Yasushi Nomura ,  Hiroshi Mitsumaki

IPC分类号： G01N3500

CPC分类号： G01N35/1002 ,  G01N35/0099 ,  G01N35/028 ,  Y10T436/2575

摘要： A chemical analyzer for measuring a concentration of components of a sample liquid, by mixing the sample liquid with reagents, so as to react the reagents upon the components thereof. The chemical analyzer includes a carrier which is constructed on a substrate and has an introducing portion through which the sample liquid is injected, distributing flow passages for distributing the sample liquid injected from the introducing portion, and plural reactor portions, each holding the sample liquid therein to be mixed with the reagent, thereby to react. A movable driver portion is provided for mounting the carrier thereon, and a reagent charging device is provided for ejecting the reagents, which are different for the respective reactor portions of the carrier. Further, a detector is provided for detecting the components after mixing the reagents with the sample liquid.

摘要翻译： 一种用于通过将样品液体与试剂混合来测量样品液体组分浓度的化学分析仪，以便将试剂与其组分反应。 该化学分析装置包括：载体，其构造在基板上，具有引入部，通过该引入部分注入样品液体;分配用于分配从引入部分注入的样品液体的流路;以及多个反应器部分，每个反应器部分将样品液体保持在其中 与试剂混合，进行反应。 提供了用于将载体安装在其上的可移动的驱动部分，并且提供了用于喷射对于载体的各反应器部分不同的试剂的试剂装料装置。 此外，提供了一种用于在将试剂与样品液体混合之后检测组分的检测器。

公开(公告)号：US06500388B1

公开(公告)日：2002-12-31

申请号：US09154698

申请日：1998-09-17

申请人： Yoshihiro Nagaoka ,  Ryo Miyake ,  Masaharu Nishida ,  Takeshi Shibuya ,  Takao Terayama ,  Hiroshi Mitsumaki

发明人： Yoshihiro Nagaoka ,  Ryo Miyake ,  Masaharu Nishida ,  Takeshi Shibuya ,  Takao Terayama ,  Hiroshi Mitsumaki

IPC分类号： G01N3510

CPC分类号： G01N35/02 ,  G01N2035/00376 ,  G01N2035/0437 ,  Y10T436/113332 ,  Y10T436/114998 ,  Y10T436/25625 ,  Y10T436/2575

摘要： An automatically analyzing apparatus includes a plurality of reaction containers for reacting a sample with a reagent, and a reaction container washing unit for washing the reaction containers through a plurality of washing steps. The reaction container washing unit includes a plurality of storage parts in each of which washing liquid containing therein reacted substance is reserved. The plurality of storage parts are sorted with different reacted substance concentrations. A supply part of the reaction container washing unit selects washing liquid of a desired reacted substance concentration among the plurality of storage parts in accordance with respective washing conditions of the reaction containers and supplies the selected washing liquid into the reaction containers for washing the respective reaction containers.

摘要翻译： 自动分析装置包括用于使样品与试剂反应的多个反应容器和用于通过多个洗涤步骤洗涤反应容器的反应容器洗涤单元。 反应容器洗涤单元包括多个储存部件，每个储存部件保留含有反应物质的洗涤液体。 以不同的反应物质浓度对多个储存部分进行分选。 反应容器洗涤单元的供应部分根据反应容器的各个洗涤条件选择多个储存部分中所需反应物质浓度的洗涤液，并将所选择的洗涤液供应到用于洗涤各反应容器的反应容器中 。