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公开(公告)号:US06410709B1
公开(公告)日:2002-06-25
申请号:US09257179
申请日:1999-02-25
申请人: Steven M. Ruben , Craig A. Rosen , Ping Fan , Hla Kyaw , Ying-Fei Wei
发明人: Steven M. Ruben , Craig A. Rosen , Ping Fan , Hla Kyaw , Ying-Fei Wei
IPC分类号: C07H2104
摘要: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
摘要翻译: 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。 还提供了用于产生人分泌蛋白质的载体,宿主细胞,抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的病症的诊断和治疗方法。
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公开(公告)号:US20090005301A1
公开(公告)日:2009-01-01
申请号:US11759448
申请日:2007-06-07
申请人: Jian Ni , Reinhard Ebner , David W. LaFleur , Paul A. Moore , Henrik S. Olsen , Craig A. Rosen , Steven M. Ruben , Daniel R. Soppet , Paul E. Young , Yanggu Shi , Kimberly A. Florence , Ying-Fei Wei , Charles Florence , Jing-Shan Hu , Yi Li , Hla Kyaw , Carrie L. Fischer , Ann M. Ferrie , Ping Fan , Ping Feng , Gregory A. Endress , Patrick J. Dillon , Kenneth C. Carter , Laurie A. Brewer , Guo-Liang Yu , Zhizhen Zeng , John M. Greene
发明人: Jian Ni , Reinhard Ebner , David W. LaFleur , Paul A. Moore , Henrik S. Olsen , Craig A. Rosen , Steven M. Ruben , Daniel R. Soppet , Paul E. Young , Yanggu Shi , Kimberly A. Florence , Ying-Fei Wei , Charles Florence , Jing-Shan Hu , Yi Li , Hla Kyaw , Carrie L. Fischer , Ann M. Ferrie , Ping Fan , Ping Feng , Gregory A. Endress , Patrick J. Dillon , Kenneth C. Carter , Laurie A. Brewer , Guo-Liang Yu , Zhizhen Zeng , John M. Greene
IPC分类号: C07K14/47 , C12N15/12 , C12N15/85 , C07K16/18 , C12Q1/68 , A61K38/14 , A61K31/7088 , G01N33/68 , C12P21/02 , C12N15/00 , C12N5/10
摘要: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
摘要翻译: 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。 还提供了用于产生人分泌蛋白质的载体,宿主细胞,抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的疾病,病症和/或病症的诊断和治疗方法。
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公开(公告)号:US06525174B1
公开(公告)日:2003-02-25
申请号:US09205258
申请日:1998-12-04
申请人: Paul Young , John M. Greene , Ann M. Ferrie , Steven M. Ruben , Craig A. Rosen , Jing-Shan Hu , Henrik S. Olsen , Reinhard Ebner , Laurie A. Brewer , Paul A. Moore , Yanggu Shi , Charles Florence , Kimberly Florence , David W. Lafleur , Jian Ni , Ping Fan , Ying-Fei Wei , Carrie L. Fischer , Daniel R. Soppet , Yi Li , Zhizhen Zeng , Hla Kyaw , Guo-Liang Yu , Ping Feng , Patrick J. Dillon , Gregory A. Endress , Kenneth C. Carter
发明人: Paul Young , John M. Greene , Ann M. Ferrie , Steven M. Ruben , Craig A. Rosen , Jing-Shan Hu , Henrik S. Olsen , Reinhard Ebner , Laurie A. Brewer , Paul A. Moore , Yanggu Shi , Charles Florence , Kimberly Florence , David W. Lafleur , Jian Ni , Ping Fan , Ying-Fei Wei , Carrie L. Fischer , Daniel R. Soppet , Yi Li , Zhizhen Zeng , Hla Kyaw , Guo-Liang Yu , Ping Feng , Patrick J. Dillon , Gregory A. Endress , Kenneth C. Carter
IPC分类号: C07K1447
CPC分类号: G01N33/68 , A61K38/00 , A61K48/00 , C07K14/47 , C07K14/4702 , C07K14/4718 , C07K2319/00 , C07K2319/02 , C12N15/11 , C12N2799/026
摘要: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
摘要翻译: 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。 还提供了用于产生人分泌蛋白质的载体,宿主细胞,抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的病症的诊断和治疗方法。
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公开(公告)号:US20060223077A1
公开(公告)日:2006-10-05
申请号:US11229770
申请日:2005-09-20
申请人: Jian Ni , Reinhard Ebner , David LaFleur , Paul Moore , Henrik Olsen , Craig Rosen , Steven Ruben , Daniel Soppet , Paul Young , Yanggu Shi , Kimberly Florence , Ying-Fei Wei , Charles Florence , Jing-Shan Hu , Yi Li , Hla Kyaw , Carrie Fischer , Ann Ferrie , Ping Fan , Ping Feng , Gregory Endress , Patrick Dillon , Kenneth Carter , Laurie Brewer , Guo-Liang Yu , Zhizhen Zeng , John Greene
发明人: Jian Ni , Reinhard Ebner , David LaFleur , Paul Moore , Henrik Olsen , Craig Rosen , Steven Ruben , Daniel Soppet , Paul Young , Yanggu Shi , Kimberly Florence , Ying-Fei Wei , Charles Florence , Jing-Shan Hu , Yi Li , Hla Kyaw , Carrie Fischer , Ann Ferrie , Ping Fan , Ping Feng , Gregory Endress , Patrick Dillon , Kenneth Carter , Laurie Brewer , Guo-Liang Yu , Zhizhen Zeng , John Greene
摘要: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
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公开(公告)号:US20050037467A1
公开(公告)日:2005-02-17
申请号:US10936773
申请日:2004-09-09
申请人: Steven Ruben , Ping Feng , David LaFleur , Paul Moore , Yanggu Shi , Hla Kyaw , Yi Li , ZhiZhen Zeng , Kenneth Carter , Gregory Endress , Ying-Fei Wei , Ping Fan , Craig Rosen
发明人: Steven Ruben , Ping Feng , David LaFleur , Paul Moore , Yanggu Shi , Hla Kyaw , Yi Li , ZhiZhen Zeng , Kenneth Carter , Gregory Endress , Ying-Fei Wei , Ping Fan , Craig Rosen
摘要: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
摘要翻译: 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。 还提供了用于产生人分泌蛋白质的载体,宿主细胞,抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的疾病,病症和/或病症的诊断和治疗方法。
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公开(公告)号:US09597965B2
公开(公告)日:2017-03-21
申请号:US14477022
申请日:2014-09-04
申请人: Ping Fan
发明人: Ping Fan
CPC分类号: B60L11/1809 , F16D43/16 , F16D2043/145 , H02K7/10 , H02K7/1846
摘要: The present invention is to provide a clutch-type electric generator for automobile axles which comprises a casing, a stator housing having a plurality of stators fixed therein, a rotor housing movably configured around the axle and having a plurality of rotors fixed therein, and a clutch mechanism. The axle penetrates the casing and rotates with respect to the casing. The clutch mechanism comprises a passive ring, a clutch disc fixed around the axle and a plurality of clutch shoes; wherein the clutch shoes can be centrifugally moved between the clutch disc and the passive ring via a plurality of connecting rods and elastic devices, and can engage with the passive ring fixed on the rotor housing for enabling the rotors to simultaneously rotate along with the axle and to rotate with respect to the stators to generate induced electricity while the automobile has reached a predetermined speed.
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公开(公告)号:US06667390B2
公开(公告)日:2003-12-23
申请号:US09756854
申请日:2001-01-10
申请人: Jian Ni , Guo-Liang Yu , Ping Fan , Reiner L. Gentz
发明人: Jian Ni , Guo-Liang Yu , Ping Fan , Reiner L. Gentz
IPC分类号: C07K14715
CPC分类号: C07K14/70578 , A61K38/00 , C07K14/4747 , C07K14/7151 , C12N2799/026
摘要: The present invention relates to a novel member of the tumor necrosis factor family of receptors. In particular, isolated nucleic acid molecules are provided encoding the human TR9 receptor. TR9 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of TR9 receptor activity.
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公开(公告)号:US07776560B2
公开(公告)日:2010-08-17
申请号:US11780643
申请日:2007-07-20
申请人: Jian Ni , Guo-Liang Yu , Ping Fan , Reiner L. Gentz
发明人: Jian Ni , Guo-Liang Yu , Ping Fan , Reiner L. Gentz
IPC分类号: C07K14/705 , C07K16/28 , C12N5/12 , G01N33/53
CPC分类号: C07K16/1271 , A61K38/00 , C07K14/4747 , C07K14/70578 , C07K14/7151 , C07K2319/00 , C07K2319/30 , C12N2799/026
摘要: The present invention relates to a novel member of the tumor necrosis factor family of receptors. In particular, isolated nucleic acid molecules are provided encoding the human TR9 receptor. TR9 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of TR9 receptor activity.
摘要翻译: 本发明涉及肿瘤坏死因子受体家族的新成员。 特别地,提供编码人TR9受体的分离的核酸分子。 还提供TR9多肽,载体,宿主细胞和用于制备它们的重组方法。 本发明还涉及用于鉴定TR9受体活性的激动剂和拮抗剂的筛选方法。
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公开(公告)号:US5968780A
公开(公告)日:1999-10-19
申请号:US19201
申请日:1998-02-05
申请人: Ping Fan , Daniel R. Soppet , Yi Li , Patrick J. Dillon
发明人: Ping Fan , Daniel R. Soppet , Yi Li , Patrick J. Dillon
IPC分类号: C12N15/09 , A61K38/00 , A61K38/22 , A61K48/00 , A61P31/18 , A61P43/00 , C07K14/475 , C07K14/705 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/12 , C12N15/16 , C12N15/63
CPC分类号: C07K14/475 , C07K14/4756 , A61K38/00 , C12N2799/026
摘要: The present invention relates to a novel DCDGF protein which is a member of a novel family of growth factors of which the prototype is called Insect-Derived Growth Factor (IDGF). In particular, isolated nucleic acid molecules are provided encoding the human DCDGF protein. DCDGF polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of DCDGF activity. Also provided are diagnostic methods for diagnosing DiGeorge Syndrome and, particularly, immune system-related disorders. and therapeutic methods for treating immune system-related disorders.
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10.
公开(公告)号:US09399380B1
公开(公告)日:2016-07-26
申请号:US14689457
申请日:2015-04-17
申请人: Ping Fan
发明人: Ping Fan
CPC分类号: B60G13/14 , B60G13/08 , B60G2202/24 , B60G2300/60 , B60G2500/10 , F03G7/08 , H02K7/1853
摘要: The present invention is to provide a vibration-type electric generator, which comprises an electric generator fixed on an automobile, having stators fixed at the inner rim of the generator, and having rotors rotatably installed inside the generator, such that when the rotors are rotated, the rotors generate a time-varying magnetic field to induce electricity on the stators; two one way bearings having shafts fixedly linked to a shaft of the rotors, respectively, such that when the bearings are respectively driven to rotate toward the same direction, the rotors are driven simultaneously to rotate toward the same direction and subsequently generate the electricity on the stators; and a hydraulic system pivotally connected to two suspension members on the automobile which are able to generate relative movement in response to the vibration of the automobile, so as to subsequently generate two forces for driving the bearings to rotate toward the same direction.
摘要翻译: 本发明提供一种振动型发电机,其包括固定在汽车上的发电机,其具有固定在发电机的内缘的定子,并且具有可旋转地安装在发电机内部的转子,使得当转子旋转时 转子产生时变磁场以引起定子上的电力; 两个单向轴承分别具有固定地连接到转子的轴的轴,使得当轴承分别被驱动以朝向相同的方向旋转时,转子被同时驱动以朝向相同的方向旋转,并且随后在 定子 以及液压系统,其枢转地连接到汽车上的两个悬挂构件,其能够响应于汽车的振动而产生相对运动,从而随后产生用于驱动轴承朝向相同方向旋转的两个力。
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