摘要:
A catheter for delivering an agent to an injection site in a wall of a patient's body lumen, with an elongated shaft having a needle-through lumen slidably containing a needle therein, and an expandable member on the distal shaft section which has a collapsed configuration and a radially expanded configuration. In the radially expanded configuration, the expandable member supports the shaft in a position spaced away from the body lumen wall, and the needle slidably exits the needle-through lumen in the extended configuration through the port spaced away from the body lumen wall as a portion of the expandable member maintains the position of the port section of the shaft in the body lumen. The expandable member typically has an open-walled, helical, or lobed configuration providing a perfusion path along the expandable member.
摘要:
Determining stability of a catheter is described. A first signal originating from a first region of a patient is monitored and a second signal originating from a second region of the patient is monitored. First components from a recurring interval of the second signal are extracted, where the recurring interval is defined by the first signal. The first components are compared to determine a first similarity value of the first components over time. The first similarity value is compared to a threshold value to determine a stability evaluation for a source of the second signal.
摘要:
A catheter which allows the rotational orientation of the distal end of the catheter to be adjusted in discrete intervals as the physician rotates the proximal end of the catheter. The catheter is designed to intentionally induce whipping but to limit the amount of whipping to a desired rotational interval.
摘要:
Delivery system for delivery of a medical device includes an inner member having a proximal section, a distal section and a longitudinal axis therebetween. The inner member has a first layer and a second layer wherein the first layer and the second layer are attached together at a first segment and a second segment. The second segment is spaced from the first segment along a length of the inner member and the first layer and the second layer are free of attachment between the first segment and the second segment. The inner member further includes at least two wires disposed along the length of the inner member between the first layer and the second layer. As disclosed, the at least two wires can include a first coil and a second coil moveable relative to each other between the first and second segments.
摘要:
Devices for delivering drugs or other treatment agents locally to the vasculature of a mammal are disclosed. These devices have several related structures and are designed to deliver the drugs to facilitate rapid mixing with the blood flowing past the devices.
摘要:
Substantially anhydrous electropolishing electrolyte solutions. The substantially anhydrous electropolishing electrolyte solutions described herein do not use water as a solvent; instead, such electropolishing electrolyte solutions use anhydrous alcohols and/or glycols as a solvent. For example, an electropolishing electrolyte solution, as described herein, may include an alcohol, at least one mineral acid, and phosphorous pentoxide (“P2O5”). Methods of electropolishing metal articles using such electropolishing electrolyte solutions are disclosed herein as well.
摘要翻译:基本无水电抛光电解液。 本文所述的基本无水的电解抛光电解质溶液不使用水作为溶剂; 相反,这种电解抛光电解质溶液使用无水醇和/或二醇作为溶剂。 例如,如本文所述的电解抛光电解质溶液可以包括醇,至少一种无机酸和五氧化二磷(“P 2 O 5”)。 使用这种电抛光电解质溶液电解抛光金属制品的方法也在本文中公开。
摘要:
A catheter for delivering an agent to an injection site in a wall of a patient's body lumen, with an elongated shaft having a needle-through lumen slidably containing a needle therein, and an expandable member on the distal shaft section which has a collapsed configuration and a radially expanded configuration. In the radially expanded configuration, the expandable member supports the shaft in a position spaced away from the body lumen wall, and the needle slidably exits the needle-through lumen in the extended configuration through the port spaced away from the body lumen wall as a portion of the expandable member maintains the position of the port section of the shaft in the body lumen. The expandable member typically has an open-walled, helical, or lobed configuration providing a perfusion path along the expandable member.
摘要:
A porous balloon or other catheter structure is formed by creating specific size pores for delivering an agent to a body lumen. The pores can be created by passing matter or energy through the surface of the catheter structure, as by a laser or a projectile. In the case of a laser, the catheter structure can be reversed so that the inner surface becomes the outer surface to convert diverging pores into converging pores. In the case of projectiles, a pore size can be achieved by selecting an appropriate size and shaped projectile to obtain the desired characteristic. Alternatively, a material to make the catheter structure can include impurities that can be removed once the catheter structure is set, leaving pores where the material formed around the impurities.
摘要:
A delivery catheter for delivery, then photo-activation of photo sensitive material has a photo-sensitive substance-delivery part and an activation part. The catheter delivers substances such as biomaterials to a target site, followed by illumination of the target using optics located at the distal tip of the catheter which are optically coupled to an extracorporeal light source. The light may be delivered by a single or multi-lumen needle, or a separate light guide passed over the catheter.
摘要:
Methods for making devices include providing a tubular member to be formed into a device, placing a removable sacrificial block material in the lumen of the tubular member and laser cutting the tubular member. A tubular member made from nickel-titanium alloy can be tightly adhered to a sacrificial sleeve utilizing the phase changes associated with nickel-titanium. A mandrel which includes an enlarged diameter section causes the workpiece to expand slightly within its elastic deformation range to dislodge islands from the workpiece. Such a mandrel could be formed from a tubular member which has a central lumen that can be used to deliver a pressurized medium to “blast” islands from the workpiece.