-
公开(公告)号：US20070126161A1
公开(公告)日：2007-06-07
申请号：US11699878
申请日：2007-01-30
申请人： William Gray , Richard Gambale
发明人： William Gray , Richard Gambale
IPC分类号： C04B33/32
CPC分类号： A61F2/01 , A61F2/013 , A61F2002/011 , A61F2002/016 , A61F2002/018 , A61F2230/0006 , A61F2230/0021 , A61F2230/005 , A61F2230/0067 , A61F2230/0086 , A61F2230/0093 , A61F2230/0097 , A61M25/09 , A61M2025/09183 , Y10T29/49604 , Y10T29/49801
摘要： A vascular filter guide wire including a collapsible filter that deploys radially in response to axial movement of a core wire relative to a shaft to trap particulate matter arising from treatment of a lesion.
摘要翻译： 一种血管过滤器引导线，包括可折叠过滤器，其可响应于芯线相对于轴的轴向运动而径向展开，以捕获由病变治疗引起的微粒物质。
-
公开(公告)号：US20050177187A1
公开(公告)日：2005-08-11
申请号：US11100034
申请日：2005-04-05
申请人： William Gray , Richard Gambale
发明人： William Gray , Richard Gambale
CPC分类号： A61F2/01 , A61F2/013 , A61F2002/011 , A61F2002/016 , A61F2002/018 , A61F2230/0006 , A61F2230/0021 , A61F2230/005 , A61F2230/0067 , A61F2230/0086 , A61F2230/0093 , A61F2230/0097 , A61M25/09 , A61M2025/09183 , Y10T29/49604 , Y10T29/49801
摘要： A vascular filter guide wire is disclosed for directing precision placement of a catheter proximate a blood vessel lesion and filtering particulate matter dislodged by treatment of the vessel. The guide wire includes an actuating mechanism, an elongated flexible core wire having a proximal end mounted to the actuating mechanism and a distal end for insertion through a vasculature to a position downstream of the restriction. A tubular flexible shaft is slidably disposed telescopically along the core wire and includes a proximal portion affixed to the actuating mechanism in movable relation to the core wire. The guide wire includes a collapsible filter at its proximal end to the distal portion of the shaft and, at its distal end, to the core wire. The filter deploys radially in response to axial movement of the core wire relative to the shaft so that it can trap particulate matter arising from treatment of the lesion.
摘要翻译： 公开了一种血管过滤器引导线，用于引导导管在血管损伤附近的精确放置并且通过处理血管而排出的颗粒物质过滤。 引导线包括致动机构，细长的柔性芯线，其具有安装到致动机构的近端和用于通过脉管系统插入到限制下游的位置的远端。 管状柔性轴可沿芯线可伸缩地可滑动地设置并且包括固定到致动机构上的与芯线可动的近端部分。 引导线在其近端处具有可收缩的过滤器，并且在其远端处包括芯线。 过滤器响应于芯线相对于轴的轴向运动而径向布置，使得其可以捕获由病变治疗引起的颗粒物质。
-
公开(公告)号：US20100286531A1
公开(公告)日：2010-11-11
申请号：US12784482
申请日：2010-05-20
申请人： S. Eric Ryan , Jing Tang , Richard Gambale
发明人： S. Eric Ryan , Jing Tang , Richard Gambale
IPC分类号： A61B6/00
CPC分类号： A61B5/0086 , A61B5/0066 , A61B5/0071 , A61B5/0075 , A61B5/0084 , A61B5/02007 , A61B5/6852 , A61B5/6853 , A61B2017/22001 , A61N5/0601
摘要： A system for analyzing a body lumen including a flexible conduit that is elongated along a longitudinal axis, the flexible conduit having a proximal end and a distal end; at least one delivery waveguide and at least one collection waveguide extending along the flexible conduit, a transmission output of the at least one delivery waveguide and a transmission input of the at least one collection waveguide located along a distal portion of the conduit; a spectrometer connected to the at least one delivery waveguide and the at least one collection waveguide, the spectrometer configured to perform diffuse reflectance spectroscopy, wherein the spectrometer emits at least one primary radiation signal of a wavelength having an absorption coefficient of between about 8 cm−1 and about 10 cm−1 when transmitted through a highly aqueous media; a controller system configured to calculate at least one of an extent, area, and volume of highly aqueous media based on the amount of absorption of the at least one primary radiation signal measured through the highly aqueous media by the spectrometer.
摘要翻译： 一种用于分析体腔的系统，包括沿着纵向轴线细长的柔性导管，所述柔性导管具有近端和远端; 至少一个输送波导和沿着柔性导管延伸的至少一个收集波导，所述至少一个输送波导的透射输出和沿着导管的远端部分定位的至少一个收集波导的透射输入; 光谱仪，其连接到所述至少一个传送波导和所述至少一个收集波导，所述光谱仪被配置为执行漫反射光谱，其中所述光谱仪发射具有约8cm -3的吸收系数的波长的至少一个初级辐射信号， 1和约10cm -1，当透过高含量介质时; 控制器系统，其被配置为基于由所述光谱仪通过所述高度水介质测量的所述至少一个主要辐射信号的吸收量来计算高度水介质的程度，面积和体积中的至少一个。
-
公开(公告)号：US20070093858A1
公开(公告)日：2007-04-26
申请号：US11604944
申请日：2006-11-28
IPC分类号： A61B17/10
CPC分类号： A61B17/0487 , A61B17/0467 , A61B17/0469 , A61B2017/0417 , A61B2017/0424 , A61B2017/0445 , A61B2017/045 , A61B2017/0451 , A61B2017/0454 , A61B2017/0456 , A61B2017/0459 , A61B2017/0464 , A61B2017/0488 , A61B2017/0496 , Y10T24/3969
摘要： Suture clips and suture clip loading, delivery, locking and severing devices in both catheter and endoscopic embodiments are disclosed that permit the delivery and application of suture clips directly in contact with or in close approximation to sutured tissue. The catheter or endoscopic versions incorporate a collet cage with a plurality of flexible collet fingers that captivate a suture clip ring and a suture clip plug for assembly with a suture. An outer sliding sleeve constrains the collet fingers when distally advanced to minimize potential trauma during delivery and assembly of the suture clip in close proximity to the stitched tissue. Proximal retraction of the sliding sleeve coupled with the distal advancement of a pusher against cam surfaces on the inner walls of the collet fingers causes the collet fingers to open. The catheter is designed to hold and assemble the suture clip in a first position and release the suture clip and sever the suture ends proximal to the suture clip in a second position. Single pusher two-step embodiments and double pusher three-step embodiments are disclosed. Suture clip designs with plugs having heads for use with the suture clip delivery catheter are also disclosed. A suture clip loading device for loading suture clip components into the delivery system as well as a threader for threading sutures into the suture clip systems are also disclosed. A method of loading, delivering and deploying suture clips is further disclosed.
摘要翻译： 公开了导管和内窥镜实施例中的缝合夹和缝合夹装载，递送，锁定和切断装置，其允许缝合夹直接与缝合组织接触或接近近似地递送和施加。 导管或内窥镜版本包括具有多个柔性夹头的夹头保持器，其夹持缝合夹环和缝合夹塞以与缝合线组装。 外滑动套筒在向远侧前进时约束夹头，以最小化缝合夹在紧靠缝合组织的递送和组装期间的潜在创伤。 与推动器的远端前进部联接的滑动套筒的近端缩回抵靠夹头指状物的内壁上的凸轮表面使得夹头指状物打开。 导管被设计成将缝合夹保持并组装在第一位置，并释放缝合夹并在第二位置将缝合线端部切割成缝合线夹。 公开了单推杆两步实施例和双推动器三步实施例。 还公开了具有插头的缝合夹设计，其具有用于缝合夹输送导管的头部。 还公开了一种用于将缝合夹组件加载到输送系统中的缝线夹装载装置以及用于将缝线穿入缝合夹系统的穿线器。 进一步公开了一种加载，递送和部署缝合夹的方法。
-
公开(公告)号：US20060009789A1
公开(公告)日：2006-01-12
申请号：US11199955
申请日：2005-08-09
申请人： Richard Gambale , Michael Weiser
发明人： Richard Gambale , Michael Weiser
IPC分类号： A61B17/10
CPC分类号： A61B17/0469 , A61B17/0487 , A61B17/1114 , A61B2017/00349 , A61B2017/00827 , A61B2017/00867 , A61B2017/0409 , A61B2017/0414 , A61B2017/0417 , A61B2017/0443 , A61B2017/0458 , A61B2017/0464 , A61B2017/06171 , A61B2017/0649 , A61B2017/1103 , A61B2017/1142 , A61B2017/308
摘要： The present invention provides tissue capture devices configured to hold tissue in a distorted configuration. The devices may hold precaptured tissue in a distorted configuration or it may change their shape to cause the tissue to become deformed. Some embodiments of the device alter the configuration in areas that remain external to the tissue, while other embodiments change their configuration in areas that are implanted in the tissue. Other embodiments may be mechanically altered to hold the tissue in a distorted shape.
摘要翻译： 本发明提供了构造成将组织保持在变形构型中的组织捕获装置。 这些装置可以将预先组织的组织保持在变形构型中，或者它们可以改变它们的形状以导致组织变形。 该装置的一些实施例在保留在组织外部的区域中改变构造，而其他实施例在植入组织的区域中改变其构型。 可以机械地改变其它实施例以将组织保持在变形形状。
-
公开(公告)号：US20050060019A1
公开(公告)日：2005-03-17
申请号：US10951735
申请日：2004-09-28
申请人： Richard Gambale , Stephen Forcucci , Michael Weiser , Sean Forde
发明人： Richard Gambale , Stephen Forcucci , Michael Weiser , Sean Forde
CPC分类号： A61F2/88 , A61F2/06 , A61F2/2493 , A61F2220/0016 , A61F2250/0067
摘要： The present invention provides a system (178) for delivering a therapeutic agent in combination with an implantable device (2) to maximize a therapeutic benefit offered by each. Preferably, the therapeutic agent is contained within a solid matrix form such as a pellet or gel to facilitate its handling and to regulate its rate of dissipation into the tissue after delivery. The implant device (2) is specially configured to receive and retain the matrix but permit blood to interact with the matrix so that the agent can be released to the blood in and around the device and the surrounding tissue. A delivery system (178) comprises an implant delivery device having an obturator (180) capable of piercing the tissue and an agent matrix delivery device (210) to place a matrix form, such as a pellet, into the interior of the implant (2) after it has been implanted. Preferably, the implant delivery device (180) and the matrix delivery device (210) are contained in one apparatus to facilitate delivery of the pellet into the embedded implant. The present invention is useful for treating tissue in any area of the body, especially ischemic tissue experiencing reduced blood flow. The present devices and methods are especially useful for treatment of ischemia of the myocardium. In treatment of the myocardium, the present implant device and matrix combination may be delivered surgically through the epicardium of the heart.
摘要翻译： 本发明提供了一种用于将治疗剂与可植入装置（2）组合递送以最大化由每个提供的治疗益处的系统（178）。 优选地，治疗剂包含在固体基质形式例如丸粒或凝胶中，以促进其处理并调节其在分娩后向组织中的耗散速率。 植入装置（2）被特别地构造成接收和保持基质，但允许血液与基质相互作用，使得试剂可以释放到装置周围的组织和周围的组织中和周围。 递送系统（178）包括植入物递送装置，其具有能够刺穿组织的闭孔器（180）和药剂矩阵输送装置（210），以将诸如颗粒的矩阵形式放置在植入物（2）的内部 ）植入后。 优选地，植入物递送装置（180）和基质递送装置（210）被包含在一个装置中以便于将颗粒递送到嵌入的植入物中。 本发明可用于治疗身体的任何区域中的组织，特别是经历血流减少的缺血组织。 本发明的装置和方法对于治疗心肌缺血特别有用。 在心肌的治疗中，本发明的植入装置和基质组合可以通过心脏的心外膜手术递送。
-
公开(公告)号：US20120078121A1
公开(公告)日：2012-03-29
申请号：US13321402
申请日：2010-05-20
申请人： S. Eric Ryan , Jing Tang , Richard Gambale
发明人： S. Eric Ryan , Jing Tang , Richard Gambale
IPC分类号： A61B5/02
CPC分类号： A61B5/0086 , A61B5/0066 , A61B5/0071 , A61B5/0075 , A61B5/0084 , A61B5/02007 , A61B5/6852 , A61B5/6853 , A61B2017/22001 , A61N5/0601
摘要： A catheter for placement within a body lumen, the catheter including a flexible conduit that is elongated along a longitudinal axis, the flexible conduit having a proximal end and a distal end, at least one delivery waveguide and at least one collection waveguide extending along the flexible conduit, a lumen-expanding inflatable balloon disposed about a portion of the conduit, a transmission output of the at least one delivery waveguide and a transmission input of the at least one collection waveguide located within the balloon; and, at least one elongate arm connected to the conduit and positioned within the balloon, the at least one elongate arm radially translatable with respect to the conduit, and wherein at least one of the transmission output and transmission input is coupled to the elongate arm.
摘要翻译： 一种用于放置在体腔内的导管，所述导管包括沿着纵向轴线细长的柔性导管，所述柔性导管具有近端和远端，至少一个输送波导和沿着所述柔性导管延伸的至少一个收集波导 导管，围绕导管的一部分设置的管腔膨胀的可膨胀气囊，所述至少一个输送波导的透射输出和位于气囊内的至少一个收集波导的透射输入; 以及连接到所述导管并且定位在所述气囊内的所述至少一个细长臂，所述至少一个细长臂相对于所述导管可径向平移，并且其中所述变速器输出和变速器输入中的至少一个联接到所述细长臂。
-
公开(公告)号：US20050033319A1
公开(公告)日：2005-02-10
申请号：US10847190
申请日：2004-05-17
申请人： Richard Gambale , Peter Lukin , Paul DiCesare , Christopher Battles , Jeffrey Radziunas , Danial Ferreira
发明人： Richard Gambale , Peter Lukin , Paul DiCesare , Christopher Battles , Jeffrey Radziunas , Danial Ferreira
CPC分类号： A61B17/0469 , A61B17/0467 , A61B17/0487 , A61B2017/00827 , A61B2017/045 , A61B2017/0464 , A61B2017/047
摘要： Provided is an endoscopic suturing system for joining internal body tissues in a variety of procedures. The system comprises a suturing capsule releasably mountable to the distal end of an endoscope and capable of forming multiple stitches in tissue at a plurality of locations without requiring withdrawal of the capsule from the patient between stitches. Also enclosed is a suture lock to secure the placed stitch that is delivered by a device introduced through the working channel of the indwelling endoscope. Suitable control handles for the suturing capsule and for the suture lock delivery device positioned at the proximal end of the endoscope are provided to facilitate operation by the user.
摘要翻译： 提供了一种用于以各种方法连接内部身体组织的内窥镜缝合系统。 该系统包括可释放地安装到内窥镜的远端的缝合胶囊，并且能够在多个位置处在组织中形成多个线圈，而不需要在线圈之间从患者中取出胶囊。 还包括缝合线锁，用于固定由通过留置内窥镜的工作通道引入的装置输送的放置针迹。 提供用于缝合胶囊和位于内窥镜的近端处的缝线锁输送装置的合适的控制手柄，以便于使用者的操作。
-
公开(公告)号：US20050004558A1
公开(公告)日：2005-01-06
申请号：US10899368
申请日：2004-07-26
申请人： Richard Gambale , Stephen Forcucci , Michael Weiser , Richard Choh , Sean Forde
发明人： Richard Gambale , Stephen Forcucci , Michael Weiser , Richard Choh , Sean Forde
CPC分类号： A61F2/94 , A61F2/2493 , A61F2230/0091 , A61F2250/0067
摘要： Implants and associated delivery systems for promoting angiogenesis in ischemic tissue are provided. The implants may be delivered percutaneously, thoracically or surgically and are particularly well suited for implantation into the myocardium of the heart. The implants are configured to be flexible so that they compress and expand with corresponding movement of the surrounding tissue into which they are implanted. The flow of blood into the implant and pooling of the blood in and around the implant leads to thrombosis and fibrin growth, a healing process that leads to angiogenesis in the tissue surrounding the implant. Additionally, the implants may contain an angiogenic substance or a thrombus of blood, preloaded or injected after implantation to aid in initiating angiogenesis.
摘要翻译： 提供了用于促进缺血组织中血管生成的植入物和相关递送系统。 植入物可以经皮，胸部或手术递送，并且特别适合于植入心脏的心肌。 植入物被构造成具有柔性的，使得它们随着植入其中的周围组织的相应运动而压缩和扩张。 血液进入植入物的流动以及血液在植入物中和周围的汇集导致血栓形成和纤维蛋白生长，这是导致植入物周围组织血管生成的愈合过程。 此外，植入物可能含有血管生成物质或血栓，预先加载或在植入后注射以帮助起始血管发生。
-
公开(公告)号：US20140005553A1
公开(公告)日：2014-01-02
申请号：US13824631
申请日：2011-09-21
申请人： S. Eric Ryan , Jing Tang , Richard Gambale
发明人： S. Eric Ryan , Jing Tang , Richard Gambale
CPC分类号： A61B5/0086 , A61B5/0062 , A61B5/0075 , A61B5/0084 , A61B5/02007 , A61B5/1076 , A61B5/4836 , A61B5/6853 , A61M25/104 , G01J3/0218 , G01J3/0264 , G01J3/42
摘要： A system is provided for probing a body lumen that includes a flexible conduit that is elongated along a longitudinal axis, the flexible conduit having a proximal end and a distal end, at least one delivery waveguide and at least one collection waveguide extending along the flexible conduit, a transmission output of the at least one delivery waveguide and a transmission input of the at least one collection waveguide located along a distal portion of the conduit. A spectrometer is connected to the at least one delivery waveguide and the at least one collection waveguide, the spectrometer configured to perform spectroscopy. A controller system is configured to calculate a distance between the flexible conduit and the wall of the body lumen based on a spectroscopic measurement of the at least one primary radiation signal that traveled between the flexible conduit and body lumen.
摘要翻译： 提供了一种用于探测体腔的系统，其包括沿着纵向轴线细长的柔性导管，所述柔性导管具有近端和远端，至少一个输送波导和沿柔性导管延伸的至少一个收集波导 ，所述至少一个传送波导的传输输出和沿着所述导管的远端部分定位的所述至少一个收集波导的传输输入。 光谱仪连接到至少一个传送波导和至少一个收集波导，该光谱仪被配置为执行光谱。 控制器系统被配置为基于在柔性导管和体腔之间行进的至少一个主要辐射信号的光谱测量来计算柔性导管和体腔壁之间的距离。
-
-
-
-
-
-
-
-
-
搜索结果
14 条记录 (耗时 0.019 秒)
