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1.发明申请公开(公告)号：US20050186546A1
公开(公告)日：2005-08-25
申请号：US11061744
申请日：2005-02-22
CPC分类号： G09B23/12
摘要： An evaluation apparatus of scientific phenomena, comprising: a base plate of a plate-like body whose surface is formed a long groove having a transversely cross-sectional area of not more than 1 mm2; and a cover plate that is disposed on a surface of the base plate in close contact therewith and forms a fine flow passage on the base plate by covering the long groove, wherein scientific phenomena in the flow passage can be visually recognized.
摘要翻译： 一种科学现象的评价装置，其特征在于，包括：板状体的基板，其表面形成有横截面积不大于1mm 2的长槽; 以及盖板，其设置在基板的与其紧密接触的表面上，通过覆盖长槽在基板上形成细流动通道，从而可以在视觉上识别流路中的科学现象。
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2.发明授权公开(公告)号：US07316569B2
公开(公告)日：2008-01-08
申请号：US11061744
申请日：2005-02-22
IPC分类号： G09B23/06
CPC分类号： G09B23/12
摘要： An evaluation apparatus of scientific phenomena, including: a base plate of a plate-like body on whose surface is formed an elongated groove having a transversely cross-sectional area of not more than 1 mm2; and a cover plate that is disposed on a surface of the base plate in close contact therewith and forms a fine flow passage on the base plate by covering the elongated groove, wherein scientific phenomena in the fine flow passage can be visually recognized.
摘要翻译： 一种科学现象的评价装置，包括：板状体的基板，其表面形成有横截面积不大于1mm 2的细长槽; 以及与基板紧密接触的表面上设置的盖板，通过覆盖细长槽而在基板上形成细流路，可以在视觉上识别细流路中的科学现象。
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公开(公告)号：US4558214A
公开(公告)日：1985-12-10
申请号：US529605
申请日：1983-09-06
申请人： Teruo Fujii , Mikizo Katsuyama
发明人： Teruo Fujii , Mikizo Katsuyama
CPC分类号： H04N1/0282 , H04N1/02815 , H04N1/029
摘要： Disclosed is an improved transmission illumination device for use in a picture scanning device such as an electronic picture scanner which can illuminate an annular region around an illuminated spot. This annular illuminated spot is produced by using an annular convex lens as part of an optical system. Since the area surrounding the illuminated spot is also illuminated, finding a desired spot on an original picture is greatly facilitated. Having an illuminated annular region does not create any problem which may arise from flare light if an iris diaphragm is provided in a light receiving head for the exclusion of the light emitted from the illuminated annular area.
摘要翻译： 公开了一种用于诸如电子图像扫描器的图像扫描装置的改进的透射照明装置，其能够照亮照明点周围的环形区域。 该环形照明光点通过使用环形凸透镜作为光学系统的一部分而产生。 由于照亮点周围的区域也被照亮，所以在原始图像上找到所需的位置被大大地简化。 如果在光接收头中设置虹膜隔膜以排除从照明的环形区域发射的光，则具有照明的环形区域不会产生可能由火炬光产生的任何问题。
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公开(公告)号：US08383409B2
公开(公告)日：2013-02-26
申请号：US13020193
申请日：2011-02-03
申请人： Shin Ohya , Takashi Inoue , Takatoki Yamamoto , Teruo Fujii , Yasuyuki Sakai , Masaki Nishikawa , Hitomi Sakai , Hirosuke Naruto
发明人： Shin Ohya , Takashi Inoue , Takatoki Yamamoto , Teruo Fujii , Yasuyuki Sakai , Masaki Nishikawa , Hitomi Sakai , Hirosuke Naruto
IPC分类号： C12N5/02
CPC分类号： C12N5/0068 , C08G2261/3424 , C08L65/04 , C12N2533/30
摘要： The invention is directed to methods for the propagation or cultivation of cells including preparing a cell culture substrate, wherein the cell culture substrate includes a substrate and a layer formed by surface modification. The layer includes a polymer containing an amino group. The polymer is produced by reacting a polymer represented by formula (II): with a polymer having at least one amino group, —NH2, capable of forming a Schiff base in a monomer of formula (II), thereby forming a polymer layer constituting the layer formed by surface modification. “n” in Formula (II) is 0 or a positive integer, and m is a positive integer. n and m represent the degree of polymerization. Formula (II) is formed by chemical vapor deposition of formyl[2.2]paracyclophane. The methods further include providing cells in a medium; inoculating the cells onto the cell culture substrate; and culturing the cells, wherein the cells adhere to the cell culture substrate.
摘要翻译： 本发明涉及细胞繁殖或培养方法，包括制备细胞培养基质，其中细胞培养基质包括基质和通过表面改性形成的层。 该层包括含有氨基的聚合物。 该聚合物通过使由式（II）表示的聚合物与具有至少一个氨基的聚合物-NH 2反应生成，该聚合物能够在式（II）的单体中形成席夫碱，从而形成构成 通过表面改性形成的层。 式（II）中的n为0或正整数，m为正整数。 n和m表示聚合度。 式（II）由甲酰基[2.2]对环磷酰胺的化学气相沉积形成。 所述方法还包括在培养基中提供细胞; 将细胞接种到细胞培养基底上; 并培养细胞，其中细胞粘附于细胞培养基质。
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公开(公告)号：US07189367B2
公开(公告)日：2007-03-13
申请号：US09950718
申请日：2001-09-13
申请人： Takatoki Yamamoto , Teruo Fujii , Jong Wook Hong , Isao Endo
发明人： Takatoki Yamamoto , Teruo Fujii , Jong Wook Hong , Isao Endo
CPC分类号： B01L7/52 , B01F13/0059 , B01J19/0093 , B01J2219/00783 , B01J2219/00828 , B01J2219/00831 , B01J2219/00873 , B01J2219/00961 , B01L3/5027 , B01L3/502707 , B01L2200/147 , B01L2300/0816 , B01L2300/0867 , B01L2300/0887 , B01L2300/1827 , B01L2400/0487
摘要： In order to be capable of a chemical reaction, analysis or the like wherein a small amount of samples is used, a reactor comprises a flat plate-like first substrate the inside of which is provided with a heating means; and a flat plate-like second substrate, which is placed on the top of the above-described first substrate, and on a surface thereof to be placed on the top of the above-described first substrate a flow channel having a predetermined contour has been defined.
摘要翻译： 为了能够进行使用少量样品的化学反应，分析等，反应器包括平板状的第一基板，其内部设有加热装置; 以及设置在上述第一基板的顶部上的平板状的第二基板，并且在其表面上放置在上述第一基板的顶部上，具有预定轮廓的流路 定义
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6.发明授权公开(公告)号：US06438471B1
公开(公告)日：2002-08-20
申请号：US09974832
申请日：2001-10-12
申请人： Makoto Katagishi , Yoshiro Mikami , Teruo Fujii , Kenji Sano
发明人： Makoto Katagishi , Yoshiro Mikami , Teruo Fujii , Kenji Sano
IPC分类号： G01S500
CPC分类号： G06Q10/06 , G01S5/0027 , G07C5/008
摘要： The present invention provides a system for performing procedures to request repair, without troubling the driver, when a car breaks down, as well as various onboard peripheral apparatuses and cellular phone used for this system. This system comprises an onboard peripheral apparatus having a failure detector, an onboard main controller for managing car information, a cellular phone which can make wireless connection to the onboard main controller, and a response center for receiving requests for car repairs and maintenance and making arrangements therefor. When a failure is detected, repair request is transmitted to the response center through wireless communication together with the user ID of the driver. Based on this request, the response center acquires remedy information from a car manufacturer and makes arrangements for repair and provides this remedy information to a repair shop.
摘要翻译： 本发明提供了一种用于执行程序来请求维修的过程，而不会使驾驶员不安，当汽车故障时，以及用于该系统的各种车载外围设备和蜂窝电话。该系统包括车载外围设备，其具有故障检测器 ，用于管理汽车信息的车载主控制器，可以与车载主控制器进行无线连接的蜂窝电话，以及用于接收汽车修理和维护请求的响应中心及其配置。 当检测到故障时，通过无线通信和驱动程序的用户ID将修复请求发送到响应中心。 根据这一要求，响应中心从汽车制造商那里获取补救信息，并进行修理安排，并将修复信息提供给维修店。
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7.发明授权Cell culture membrane, cell culture substrate, and method for manufacturing cell culture substrate 有权细胞培养膜，细胞培养基质和细胞培养基质的制造方法公开(公告)号：US09492842B2
公开(公告)日：2016-11-15
申请号：US14128089
申请日：2012-06-22
申请人： Yasuo Yoshimoto , Kentaro Kamimae , Yuki Tanabe , Taku Oguni , Takashi Inoue , Tsutomu Mochizuki , Makoto Hirama , Teruo Fujii , Hiroshi Kimura , Hideto Tozawa
发明人： Yasuo Yoshimoto , Kentaro Kamimae , Yuki Tanabe , Taku Oguni , Takashi Inoue , Tsutomu Mochizuki , Makoto Hirama , Teruo Fujii , Hiroshi Kimura , Hideto Tozawa
CPC分类号： B05D1/60 , C12M23/20 , C12M25/02 , C12N5/0068 , C12N2533/30
摘要： Provided is: a cell culture membrane, which is free from materials derived from living organisms, can easily be industrially mass-produced, exhibits superior long-term storage properties and chemical resistance, has excellent cell adhesion properties and long-term culture properties and is capable of replicating a cell adhesion morphology that is similar to that of collagen derived from living organisms and being used for conventional cell cultivation. Also provided are a cell culture substrate, and a method for manufacturing the cell culture substrate. In the present invention, as a cell adhesion layer, a polymer membrane represented by formula (I) is formed on the base of a cell culture substrate so as to have a membrane thickness equal to or greater than 0.2 μm (in the formula, R1 and R2 represent a —(CH2)n—NH2 moiety (n is an integer of 1-10 inclusive.) or H, with at least one of R1 and R2 being a —(CH2)n—NH2 moiety. Moreover, l and m are positive integers expressing polymerization degree).
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公开(公告)号：US20090042295A1
公开(公告)日：2009-02-12
申请号：US11889067
申请日：2007-08-08
申请人： Shin Ohya , Takashi Inoue , Takatoki Yamamoto , Teruo Fujii , Yasuyuki Sakai , Masaki Nishikawa , Hitomi Sakai , Hirosuke Naruto
发明人： Shin Ohya , Takashi Inoue , Takatoki Yamamoto , Teruo Fujii , Yasuyuki Sakai , Masaki Nishikawa , Hitomi Sakai , Hirosuke Naruto
IPC分类号： C12N5/06
CPC分类号： C12N5/0068 , C08G2261/3424 , C08L65/04 , C12N2533/30
摘要： A cell culture substrate which is durable and which can be readily produced in commercial scale at a low cost, and its production method are provided. The cell culture substrate comprises a substrate and a layer formed by surface modification, which comprises a polymer containing amino group produced by reacting a polymer represented by the following formula (II): (wherein n is 0 or a positive integer, and m is a positive integer, the n and m representing degree of polymerization) formed by chemical vapor deposition of formyl[2.2]paracyclophane represented by the following formula (I): (wherein k is 0 or 1) with a polymer having at least one amino group (—NH2) capable of forming Schiff base in its monomer. The production method of the cell culture substrate comprises the step of synthesizing such polymer on the substrate.
摘要翻译： 提供耐久性且能够以低成本容易地以商业规模生产的细胞培养基材及其制造方法。 细胞培养基材包括基材和通过表面改性形成的层，其包含通过使由下式（II）表示的聚合物反应而生成的含氨基的聚合物：（其中n为0或正整数，m为 正整数，代表聚合度的n和m）通过化学气相沉积由下式（I）表示的甲酰基[2.2]对环烷烃形成：（其中k为0或1）与具有至少一个氨基的聚合物 -NH2）能够在其单体中形成席夫碱。 细胞培养基质的制造方法包括在基材上合成这样的聚合物的工序。
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9.发明申请Electrical signal measuring device for cells in culture and electrical signal measuring method that uses same device 审中-公开用于培养细胞的电信号测量装置和使用相同装置的电信号测量方法公开(公告)号：US20070212773A1
公开(公告)日：2007-09-13
申请号：US11707588
申请日：2007-02-15
申请人： Teruo Fujii , Yasuyuki Sakai , Serge Ostrovidov
发明人： Teruo Fujii , Yasuyuki Sakai , Serge Ostrovidov
IPC分类号： C12M1/34
CPC分类号： C12M41/36 , C12M29/04 , C12M29/10 , C12M41/46 , G01N33/4833
摘要： An electrical signal measuring device that can measure electrical characteristics of cells in culture in real time and with high accuracy while maintaining them in a favorable state and an electrical signal measuring method that uses the device are disclosed. The electrical signal measuring device 1 for cells in culture includes a support body 2, a compartment in the support body, a semipermeable membrane 3, and electrodes, in which the compartment is divided by the semipermeable membrane 3 into an upper compartment 4 and a lower compartment 5; an upper electrode 61 is provided in the upper compartment 4, and a lower electrode 62 that faces the upper electrode 61 and whose facing surface 621 is in contact with the semipermeable membrane 3 is provided in the lower compartment 5; and an upper perfusion channel and a lower perfusion channel are provided in the support body 2 to separately perfuse fluid in the upper compartment 4 and the lower compartment 5 is disclosed.
摘要翻译： 公开了一种电信号测量装置，其能够实时且准确地测量培养中的细胞的电特性，同时保持它们处于良好状态，并且使用该装置的电信号测量方法。 用于培养细胞的电信号测量装置1包括支撑体2，支撑体中的隔室，半透膜3和电极，其中隔室被半透膜3分成上隔室4和下隔室 隔间5; 在上部隔间4设置有上部电极61，并且在下部隔室5中设置面向上部电极61并且其面对面621与半透膜3接触的下部电极62; 并且在支撑体2中设置有上部灌注通道和下部灌注通道，以分开地灌注上部隔室4中的流体，并且公开了下部隔室5。
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10.发明授权公开(公告)号：US06920382B2
公开(公告)日：2005-07-19
申请号：US10840247
申请日：2004-05-07
申请人： Makoto Katagishi , Yoshiro Mikami , Teruo Fujii , Kenji Sano
发明人： Makoto Katagishi , Yoshiro Mikami , Teruo Fujii , Kenji Sano
IPC分类号： G01M17/007 , G01S5/00 , G06F17/30 , G06Q10/00 , G06Q10/06 , G06Q50/00 , G06Q50/10 , G07C5/00 , G08G1/13 , H04B7/26 , H04W4/00 , H04W4/04 , G05S5/00
CPC分类号： G06Q10/06 , G01S5/0027 , G07C5/008
摘要： The present invention provides a system for performing procedures to request repair, without troubling the driver, when a car breaks down, as well as various onboard peripheral apparatuses and cellular phone used for this system.This system comprises an onboard peripheral apparatus having a failure detector, an onboard main controller for managing car information, a cellular phone which can make wireless connection to the onboard main controller, and a response center for receiving requests for car repairs and maintenance and making arrangements therefor. When a failure is detected, repair request is transmitted to the response center through wireless communication together with the user ID of the driver. Based on this request, the response center acquires remedy information from a car manufacturer and makes arrangements for repair and provides this remedy information to a repair shop.
摘要翻译： 本发明提供了一种用于执行程序来请求修理的过程，而不会使驾驶员困扰汽车故障，以及用于该系统的各种车载外围设备和蜂窝电话。 该系统包括具有故障检测器的车载外围设备，用于管理汽车信息的车载主控制器，可以与车载主控制器进行无线连接的蜂窝电话以及用于接收汽车修理和维护和制作安排的请求的响应中心 因此。 当检测到故障时，通过无线通信和驱动程序的用户ID将修复请求发送到响应中心。 根据这一要求，响应中心从汽车制造商那里获取补救信息，并进行修理安排，并将修复信息提供给维修店。
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