公开(公告)号：US20120295531A1

公开(公告)日：2012-11-22

申请号：US13490766

申请日：2012-06-07

申请人： Urs T. Duerig ,  Bernd W. Gotsmann ,  Emanuel Loertscher ,  Daniel Widmer

发明人： Urs T. Duerig ,  Bernd W. Gotsmann ,  Emanuel Loertscher ,  Daniel Widmer

IPC分类号： B01L1/04 ,  F24F7/007 ,  H05K9/00 ,  F24F9/00

CPC分类号： B01L1/04 ,  B01L2200/0626 ,  B01L2200/0636 ,  F24F7/10 ,  F24F2221/40

摘要： A method for operating the arrangement for a laboratory room confined by a floor, a ceiling and walls connecting the floor with the ceiling, including inducing an air flow from an air inlet through a platform to an air outlet in a substantially laminar fashion. The arrangement includes a main base suspended on the floor; a tool base arranged on the main base; a platform arranged around the tool base, wherein the platform is permeable for air, and the platform is suspended at the walls; the air inlet arranged below the platform; the air outlet arranged above the tool base; and air guides for directing an air flow upwards.

摘要翻译： 一种用于操作由地板，天花板和连接地板与天花板连接的墙壁的实验室的布置的方法，包括以基本层叠的方式引导从空气入口通过平台到空气出口的空气流。 该装置包括悬挂在地板上的主基座; 设置在主基座上的工具基座; 围绕所述工具基座布置的平台，其中所述平台对于空气是可渗透的，并且所述平台悬挂在所述壁上; 空气入口布置在平台下方; 所述出气口布置在所述工具基座上方; 以及用于引导空气流向上的空气引导件。

公开(公告)号：US07670560B2

公开(公告)日：2010-03-02

申请号：US11414824

申请日：2006-05-01

申请人： G. Paul Neitzel

发明人： G. Paul Neitzel

IPC分类号： B01L3/02

CPC分类号： B01L3/502792 ,  B01J2219/00387 ,  B01J2219/00722 ,  B01L3/502784 ,  B01L2200/0626 ,  B01L2200/0673 ,  B01L2400/0406 ,  B01L2400/0442 ,  B01L2400/0448

摘要： Embodiments of droplet transport systems and methods are disclosed for levitating and transporting single or encapsulated droplets using thermocapillary convection. One method embodiment, among others comprises providing a droplet of a first liquid; and applying thermocapillary convection to the droplet to levitate and move the droplet.

摘要翻译： 公开了液滴输送系统和方法的实施例，用于使用热毛细对流来悬浮和输送单个或包封的液滴。 一个方法实施例，其中包括提供第一液体的液滴; 并且将液滴的热毛细对流施加到液滴上以悬浮和移动液滴。

公开(公告)号：US20240181441A1

公开(公告)日：2024-06-06

申请号：US18546575

申请日：2022-02-17

申请人： POLY PICO TECHNOLOGIES LIMITED

发明人： Gabriel LEEN ,  Nikolay PAVLOV

IPC分类号： B01L3/02

CPC分类号： B01L3/0268 ,  B01L2200/0626 ,  B01L2400/0415

摘要： An apparatus provides precise steering of inkjet droplets to a substrate by use of multipole arrangement with electrodes on a resistive plate. There may be droplet detection based on charge sensing. A hexagonal spiral deposition pattern on a target substrate allows fast uniform printing covering a nearly circular hexagonal area. There may be six electrodes arranged to form a cubic enclosure, and injected droplets may be merged within the enclosure, and their charge controlled by merging of source droplets of differing charges to provide a net charge for biasing onward steering.

公开(公告)号：US20180348149A1

公开(公告)日：2018-12-06

申请号：US15778722

申请日：2016-10-28

申请人： PAUL SCHERRER INSTITUT

发明人： TAKASHI TOMIZAKI ,  SOICHIRO TSUJINO

IPC分类号： G01N23/20025 ,  B01L3/02 ,  G01N23/207 ,  G10K15/00 ,  B01L3/06

CPC分类号： G01N23/20025 ,  B01L3/0241 ,  B01L3/06 ,  B01L2200/0626 ,  B01L2400/0439 ,  G01N23/207 ,  G01N2223/0566 ,  G01N2223/3306 ,  G10K15/00

摘要： A method and a system for resolving a crystal structure of a crystal at atomic resolution by collecting X-ray diffraction images. The method includes the steps: a) ejecting a droplet of fluid comprising single or multiple of crystal into an ultrasonic acoustic levitator; b) levitating the droplet of fluid with the crystal in the ultrasonic acoustic levitator; b) monitoring the position and the spinning of the droplet with a visualization apparatus; c) applying X-ray to the crystal, the X-ray stemming from an X-ray source; and d) detecting the X-ray diffraction images from the crystal irradiated by the X-ray source by an X-ray detector being capable to capture two dimensional diffraction patterns.

公开(公告)号：US20180284423A1

公开(公告)日：2018-10-04

申请号：US15475410

申请日：2017-03-31

申请人： Sharp Microfluidic Solutions Limited

发明人： Laura Huang ,  Tim Boyle

IPC分类号： G02B26/00 ,  H01L27/12

CPC分类号： G02B26/005 ,  B01L3/502792 ,  B01L2200/0626 ,  B01L2200/143 ,  B01L2300/0663 ,  B01L2300/161 ,  B01L2400/0427 ,  H01L27/1214

摘要： A microfluidic system includes an electro-wetting on dielectric (EWOD) device and a control system that controls actuation voltages applied to the element array of the EWOD device to perform manipulation operations as to fluid droplets. The control system applies a sequence of actuation voltages to a portion of the array elements associated with a droplet to maintain the droplet in a desired droplet state corresponding to a predetermined droplet property. The sequence of actuation voltages includes an actuation-on period in which the portion of the array elements associated with the droplet is actuated and an actuation-off period in which the portion of the array elements associated with the droplet is not actuated, and the actuation-off period is non-zero. The control system may apply a sequence of actuation voltages comprising a predetermined duty cycle, and/or the actuation voltages may be applied in accordance with a sensor based intervention.

公开(公告)号：US20130340840A1

公开(公告)日：2013-12-26

申请号：US13917585

申请日：2013-06-13

申请人： Massachusetts Institute of Technology

发明人： Sushant Anand ,  Kripa K. Varanasi

IPC分类号： F15D1/00

CPC分类号： F15D1/0065 ,  B01L3/502746 ,  B01L3/502769 ,  B01L2200/0626 ,  B01L2400/0469 ,  Y10T137/0391

摘要： Methods described herein provide a way to reduce or eliminate drag and adhesion of a substance flowing over a surface by creating a vapor cushion via evaporation of a phase-changing material of or on the surface or encapsulated within textures of the surface. The vapor cushion causes the flowing substance to be suspended over the surface, greatly reducing friction, drag, and adhesion between the flowing substance and the surface. The temperature of the flowing substance is above the sublimation point and/or melting point of the phase-changing material. The phase-changing material undergoes a phase change (evaporation or sublimation) upon contact with the flowing substance due to local heat transfer from the flowing substance to the material, generating a vapor cushion between the solid or liquid material and the flowing substance.

摘要翻译： 本文所述的方法提供了一种减少或消除流过表面的物质的阻力和粘附的方法，其通过蒸发表面上或表面上的相变材料或封装在表面的纹理内而产生蒸气垫。 蒸汽垫使流动物质悬浮在表面上，大大降低了流动物质与表面之间的摩擦，阻力和粘附力。 流动物质的温度高于相变材料的升华点和/或熔点。 与流动物质接触时，相变材料由于从流动物质到材料的局部热传递而经历相变（蒸发或升华），在固体或液体物质与流动物质之间产生蒸气垫。

公开(公告)号：US20120291376A1

公开(公告)日：2012-11-22

申请号：US13466205

申请日：2012-05-08

申请人： Urs T. Duerig ,  Bernd W. Gotsmann ,  Emanuel Loertscher ,  Daniel Widmer

发明人： Urs T. Duerig ,  Bernd W. Gotsmann ,  Emanuel Loertscher ,  Daniel Widmer

IPC分类号： F24F7/00 ,  E04C2/52 ,  E04F17/04

CPC分类号： B01L1/04 ,  B01L2200/0626 ,  B01L2200/0636 ,  F24F7/10 ,  F24F2221/40

摘要： An arrangement for a laboratory room that is confined by a floor, a ceiling and walls connecting the floor with the ceiling, the arrangement comprises: a main base suspended on the floor; a tool base arranged on the main base; a platform arranged around the tool base, wherein the platform is permeable for air, and the platform is suspended at the walls; an air inlet arranged below the platform; an air outlet arranged above the tool base; and air guides for directing an air flow upwards at least partially parallel to the main base and/or the tool base.

摘要翻译： 由地板，天花板和连接地板和天花板的墙壁所限定的实验室的布置，该装置包括：悬挂在地板上的主基座; 设置在主基座上的工具基座; 围绕所述工具基座布置的平台，其中所述平台对于空气是可渗透的，并且所述平台悬挂在所述壁上; 设置在平台下方的进气口; 布置在工具基座上方的空气出口; 以及用于将气流向上引导至少部分平行于主基座和/或工具基座的空气引导件。

公开(公告)号：US20100255556A1

公开(公告)日：2010-10-07

申请号：US12602586

申请日：2008-06-26

申请人： Thomas Hunt ,  David Issadore ,  Robert Westervelt

发明人： Thomas Hunt ,  David Issadore ,  Robert Westervelt

IPC分类号： C12N13/00 ,  C12M1/42

CPC分类号： B01L3/502792 ,  B01L3/502761 ,  B01L2200/0626 ,  B01L2200/0647 ,  B01L2200/0652 ,  B01L2200/0673 ,  B01L2300/0819 ,  B01L2300/089 ,  B01L2400/0415 ,  B01L2400/043

摘要： The present disclosure relates generally to methods and apparatus for manipulating, detecting, imaging, and/or identifying particles, fluids, or other objects via electromagnetic fields, including methods and apparatus for identifying, sorting, splitting, coalescing, and/or reacting such particles, fluids, or other objects. Certain aspects of the invention are generally directe to methods and devices for producing electric or magnetic fields, e.g., from one or more field-generating components (200) (for example, arranged in an array), to control or manipulate a particle, fluid, or other object. For example, a fluidic droplet may be identified, sorted, separated, split, fused or coalesced, mixed, charged, sensed, determined, etc., using various systems and methods as described herein. In some cases, a particle, a fluidic species (e.g., a droplet), or another object may be contained or constrained by one or more layers of fluid. Other aspects of the invention are directed to methods of making such devices, methods of promoting the making or use of such devices, or the like.

摘要翻译： 本公开总体上涉及用于通过电磁场操纵，检测，成像和/或识别颗粒，流体或其它物体的方法和装置，包括用于识别，分选，聚结和/或反应这种颗粒的方法和装置 ，流体或其他物体。 本发明的某些方面通常涉及用于产生电场或磁场的方法和装置，例如，来自一个或多个场产生部件（200）（例如，排列成阵列），以控制或操纵颗粒，流体 ，或其他对象。 例如，使用本文所述的各种系统和方法，可以识别，分类，分离，分离，融合或聚结，混合，充电，感测，确定等流体液滴。 在一些情况下，颗粒，流体物质（例如，液滴）或另一物体可以被一层或多层流体包含或约束。 本发明的其它方面涉及制造这种装置的方法，促进制造或使用这种装置的方法等。

公开(公告)号：US20040055536A1

公开(公告)日：2004-03-25

申请号：US10253372

申请日：2002-09-24

发明人： Pramod Kolar ,  Richard B. Fair

IPC分类号： C12Q001/68 ,  B05C005/02 ,  B05B005/025

CPC分类号： B01L3/0241 ,  B01J2219/0036 ,  B01J2219/0065 ,  B01J2219/00653 ,  B01L2200/0626 ,  B01L2300/089 ,  B01L2400/027 ,  B01L2400/0415 ,  B01L2400/0427 ,  B05B5/0255 ,  B41J2002/14395 ,  C40B60/14

摘要： An apparatus for actuating a droplet comprises a first conductive layer, a second conductive layer, a conductive elongate element, and a voltage source. The first conductive layer comprises a first hydrophobic surface. The second conductive layer comprises a hydrophilic surface facing the first hydrophobic surface. The second conductive layer is axially spaced from the first conductive layer to define a gap therebetween. The conductive medial element is disposed in the gap between the first and second conductive layers, and comprises a second hydrophobic surface. The voltage source communicates with the second conductive layer and the elongate element. By applying a voltage potential between the elongate element and the second conductive layer, droplets can be electrostatically actuated so as to move from the first conductive layer into contact with the second conductive layer. The apparatus is particularly useful in the synthesis of microarrays of biological, chemical, or biochemical samples.

摘要翻译： 用于致动液滴的装置包括第一导电层，第二导电层，导电细长元件和电压源。 第一导电层包括第一疏水表面。 第二导电层包括面向第一疏水表面的亲水表面。 第二导电层与第一导电层轴向间隔开以限定它们之间的间隙。 导电内侧元件设置在第一和第二导电层之间的间隙中，并且包括第二疏水表面。 电压源与第二导电层和细长元件连通。 通过在细长元件和第二导电层之间施加电压电位，可以静电致动液滴，以便从第一导电层移动到与第二导电层接触。 该装置特别可用于合成生物，化学或生化样品的微阵列。

公开(公告)号：US11998913B2

公开(公告)日：2024-06-04

申请号：US18120537

申请日：2023-03-13

申请人： Cellular Highways Ltd.

发明人： Mikhail Bashtanov ,  Richard Gold ,  Calum Hayes ,  Fred Hussain ,  Robyn Pritchard ,  Salman Samson Rogers ,  Nuno Varelas ,  Alexander Zhukov

IPC分类号： B01L3/00 ,  G01N15/14 ,  G01N15/1404 ,  G01N15/1434 ,  G01N15/149

CPC分类号： B01L3/502753 ,  B01L3/502715 ,  B01L3/50273 ,  B01L3/502738 ,  B01L3/502776 ,  G01N15/1434 ,  B01L2200/0626 ,  B01L2200/0631 ,  B01L2200/0636 ,  B01L2200/0652 ,  B01L2200/0673 ,  B01L2300/06 ,  B01L2300/0654 ,  B01L2300/0816 ,  B01L2300/0864 ,  B01L2300/0883 ,  B01L2300/1805 ,  B01L2400/0442 ,  B01L2400/0487 ,  B01L2400/06 ,  G01N2015/1413 ,  G01N15/149

摘要： A single junction sorter for a microfluidic particle sorter, the single-junction sorter comprising: an input channel, configured to receive a fluid containing particles; an output sort channel and an output waste channel, each connected to the input channel for receiving the fluid therefrom; a bubble generator, operable to selectively displace the fluid around a particle to be sorted and thereby to create a transient flow of the fluid in the input channel; and a vortex element, configured to cause a vortex in the transient flow in order to direct the particle to be sorted into the output sort channel.