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42 条记录 (耗时 0.015 秒)

    Fragrant composition
    4.
    发明授权
    Fragrant composition 失效
    芬芳的成分

    公开(公告)号：US5235110A

    公开(公告)日：1993-08-10

    申请号：US853870

    申请日：1992-03-20

    申请人： Toshiro Yamada ,  Hiroshi Fujisawa ,  Hideyuki Tanaka

    发明人： Toshiro Yamada ,  Hiroshi Fujisawa ,  Hideyuki Tanaka

    IPC分类号： C07C49/395 ,  C07C59/205 ,  C11B9/00

    CPC分类号： C07C59/205 ,  C07C49/395 ,  C11B9/00

    摘要： The invention discloses a process for preparing a 2,3-di-substituted cyclopentanone mixture containing an enriched cis-2,3-di-substituted cyclopentanone which comprises heating a trans-2,3-di-substituted cyclopentanone in the presence of 100 ppm or less (weight basis) of a metal carbonate based on the cyclopentanone. The invention also discloses a fragrant composition comprising 20 to 50 wt % of 2,3-di-substituted cis-methyl (dihydro) jasmonates and 80 to 50 wt % of 2,3-di-substituted (dihydro) trans-methyl (dihydro) jasmonates. The fragrant composition has jasmine flower-like fragrance.

    摘要翻译： 本发明公开了一种制备含有富含顺式-2,3-二取代环戊酮的2,3-二取代环戊酮混合物的方法，该方法包括在100ppm存在下加热反式-2,3-二取代的环戊酮 或更少（基于重量）基于环戊酮的金属碳酸酯。 本发明还公开了一种芳香组合物，其包含20至50重量％的2,3-二取代的顺式 - 甲基（二氢）茉莉酮酸酯和80至50重量％的2,3-二取代的（二氢）反式甲基（二氢 ）茉莉酸 芳香的成分含有茉莉花般的香味。

    Retrosteroid a-ring formation
    5.
    发明授权
    Retrosteroid a-ring formation 失效
    回波环形成

    公开(公告)号：US3591607A

    公开(公告)日：1971-07-06

    申请号：US3591607D

    申请日：1966-04-19

    申请人： HOFFMANN LA ROCHE

    发明人： BASEL ANDOR FURST ,  KOCH WOLFGANG ,  USKOKOVIC MILAN RADOJE

    IPC分类号： C07C59/205 ,  C07C59/215 ,  C07C171/07 ,  C07D3/00

    CPC分类号： C07C59/205 ,  C07C59/215 ,  C07C2603/16

    摘要： IS A MEMBER SELECTED FROM THE GROUP CONSISTING OF HYDROGEN, ALKYL, HYDROXY, LOWER ALKANOYLOXY; AND HALO; Q, WHEN TAKEN ALONE, IS OXO; T1, WHEN TAKEN ALONE, IS A MEMBER SELECTED FROM THE GROUP CONSISTING OF ALKALI METAL OXY AND LOWER ALKOXY; AND T1 AND Q, WHEN TAKEN TOGETHER, ARE NITRILE. THESE COMPOUNDS ARE INTERMEDIATES WHICH CAN BE CONVERTED TO A KNOWN CLASS OF ENDOCRINOLOGICALLY ACTIVE 9,10-STEROIDS.

    Y-CH2-CO-

    Y IS A MEMBER SELECTED FORM THE GROUP CONSISTING OF HYDROGEN, HALO, AND HYDROXY; R17A, WHEN R17B IS HYDROXY AND LOWER ALKANOYLOXY, IS A MEMBER SELECTED FROM THE GROUP CONSISTING OF HYDROGEN AND LOWER ALIPHATIC HYDRCARBYL, AND, WHEN R17B IS

    Y-CH2-CO-

    R17B IS A MEMBER SELECTED FROM THE GROUP CONSISTING OF HYDROXY, LOWER ALKANOYLOZY, AND

    >C(-R17B)-R17A

    R1 IS A MEMBER SELECTED FROM THE GROUP CONSISTING OF HYDROGEN, LOWER ALKYL, LOWER ALKOXY, AND LOWER ALKYLTHIO: R2 IS A MEMBER SELECTED FROM THE GROUP CONSISTING OF HYDROGEN, LOWER ALKYL, LOWER ALKOXY, AND LOWER ALKYLTHIO; R6 IS A MEMBER SELECTED FROM THE GROUP CONSISTING OF HYDROGEN, LOWER ALKYL, LOWER ALKYLTHIO, LOWER ALKANOYLTHIO, AND HALO; R7 IS A MEMBER SELECTED FROMTHE GROUP CONSISTING OF HYDROGEN, LOWER ALKYL, LOWER ALKYLTHIO, LOWER ALKANOYLTHIO, AND HALO; R11 IS A MEMBER SELECTED FROM THE GROUP CONSISTING OF HYDORGEN, HYDROXT, AND LOWER ALKANOYLOXY; R16 IS A MEMBER SELECTED FROM THE GROUP CONSISTING OF HYDROGEN, LOWER ALKYL, HYDORXY, LOWER ALKOZY, LOWER ALKANOYLOXY, AND, WHEN THE 17B-SUBSTITUENT IS ACETYL OR SUBSTITUTED ACETYL, FLUORINE; Z IS A MEMBER SELECTED FROM THE GROUP CONSISTING OF CARBONYL, (17B-HYDROXY-17A-LOWER ALKANOIC ACID LACTONE), AND

    8-(Q=C(-T1-CH(-R2)-CH(-R1)-)DECALIN

    1-R11,3-C,3,4-(-Z-CH(-R16)-CH2-),5-R7,6-R6,7-(O=),8-CH3,

    3,5-SECO-9B,10A STEROIDS OF THE FORMULA:

    WHEREIN:

    Process for the preparation of (+)-(1R) -cis-3-oxo-2-pentyl-1-cyclopentaneacetic acid
    9.
    发明授权
    Process for the preparation of (+)-(1R) -cis-3-oxo-2-pentyl-1-cyclopentaneacetic acid 失效
    制备（+） - （1R） - 顺式-3-氧代-2-戊基-1-环戊烷乙酸的方法

    公开(公告)号：US5728866A

    公开(公告)日：1998-03-17

    申请号：US591509

    申请日：1996-02-07

    申请人： Valentin Rautenstrauch ,  Jean-Jacques Riedhauser

    发明人： Valentin Rautenstrauch ,  Jean-Jacques Riedhauser

    IPC分类号： B01J31/22 ,  B01J31/24 ,  C07B61/00 ,  C07C51/02 ,  C07C51/36 ,  C07C59/11 ,  C07C59/205 ,  C07C59/82 ,  C07C67/00 ,  C07C67/11 ,  C07C69/716 ,  C07C69/738 ,  C07C69/757 ,  C07C69/74 ,  C07C61/06

    CPC分类号： B01J31/0237 ,  B01J31/2433 ,  B01J31/2452 ,  C07C51/36 ,  C07C59/11 ,  C07C59/205 ,  C07C59/82 ,  C07C69/757 ,  B01J2231/645 ,  B01J2531/0266 ,  B01J2531/821 ,  B01J2531/96 ,  B01J2540/32

    摘要： A method for preparing 3-oxo-2-pentyl-1-cyclopentaneacetic acid or methyl 3-oxo-2-pentyl-1-cyclopentaneacetate, essentially in the form of the (+)-(1R)-cis isomer thereof. The method includes the steps of (a) catalytically hydrogenating a compound of the formula (I), ##STR1## wherein M is a hydrogen atom, an alkali metal or alkaline earth metal atom, or a group NR.sub.4, where R is a hydrogen or a lower alkyl radical, in a suitable solvent and in the presence of a catalyst consisting of an Ru(II) complex comprising chiral ligands that contain a 2,2'-bis(diphenylphosphino)-1,1'-dinaphthyl (BINAP) radical or a 1,2-bis(2,5-dialkylphospholano)benzyl (DuPHOS) radical, wherein the alkyl is a C.sub.2 or C.sub.3 radical, to give a compound of formula (II), ##STR2## wherein M has the meaning given above, essentially in the form of the (+)-(1R)-cis isomer thereof; (b) if required, acidifying, in a per se known manner, the compound of formula (II), wherein M is an alkali metal or alkaline earth metal atom, or a group N.sub.4, where R is hydrogen or a lower alkyl radical, to give (+)-(1R)-cis-3-oxo-2-pentyl-1-cyclopentaneacetic acid; and (c) if required, esterifying the resulting (+)-(1R)-cis-3-oxo-2-pentyl-1-cyclopentaneacetic acid under suitable conditions to form methyl (+)-(1R)-cis-3-oxo-2-pentyl-1-cyclopentaneacetate.

    摘要翻译： PCT No.PCT / IB95 / 00505 Sec。 371日期：1996年2月7日 102（e）日期1996年2月7日PCT Filed 1995年6月21日PCT公布。 公开号WO96 / 00206 日期1996年1月4日一种制备3-氧代-2-戊基-1-环戊烷乙酸或3-氧代-2-戊基-1-环戊基乙酸甲酯的方法，其基本上为（+） - （1R） - 顺式 异构体。 该方法包括以下步骤：（a）催化氢化式（I）化合物，其中M为氢原子，碱金属或碱土金属原子或NR4基团，其中R为 在合适的溶剂中和在包含Ru（II）络合物的催化剂存在下，包含含有2,2'-双（二苯基膦基）-1,1'-二萘基（二苯基膦基）-1,1'-二萘基 BINAP）基或1,2-双（2,5-二烷基磷酰）苄基（DuPHOS）基团，其中烷基是C2或C3基团，得到式（II）化合物，其中 M具有上面给出的含义，基本上是其（+） - （1R） - 顺式异构体的形式; （b）如果需要，以本身已知的方式酸化其中M为碱金属或碱土金属原子的式（II）化合物或其中R为氢或低级烷基的基团N4， 得到（+） - （1R） - 顺式-3-氧代-2-戊基-1-环戊烷乙酸; 和（c）如果需要，在合适的条件下酯化所得的（+） - （1R） - 顺式-3-氧代-2-戊基-1-环戊烷乙酸，形成（+） - （1R） - 顺-3- -2-戊基-1-环戊烷乙酸酯。