公开(公告)号：US20240191164A1

公开(公告)日：2024-06-13

申请号：US18532529

申请日：2023-12-07

申请人： Voodoo Scientific USA, Inc.

发明人： Joana Montenegro ,  Martin Duncan Enriquez

IPC分类号： C12G3/08 ,  C12G3/021 ,  C12G3/07 ,  C12N9/02

CPC分类号： C12G3/08 ,  C12G3/021 ,  C12G3/07 ,  C12N9/0008 ,  C12Y102/01003 ,  C12Y102/01004

摘要： Methods of producing a consumable alcoholic product involve utilizing one or more enzymes to reduce or remove an oral pain response otherwise experienced upon consumption of the product. Methods involve admixing at least one oxidase with a fermentate and optionally distilling the fermentate to produce a consumable alcoholic product, such as a distilled alcohol. Methods involve admixing at least one oxidase comprising an aldehyde dehydrogenase.

公开(公告)号：US20150079646A1

公开(公告)日：2015-03-19

申请号：US14370959

申请日：2012-12-17

申请人： Jens Nielsen ,  Verena Siewers ,  Yun Chen ,  Laurent Daviet ,  Michel Schalk

发明人： Jens Nielsen ,  Verena Siewers ,  Yun Chen ,  Laurent Daviet ,  Michel Schalk

IPC分类号： C12N15/81 ,  C12P7/16 ,  C12N9/10 ,  C12N9/04 ,  C12N9/02 ,  C12N9/00 ,  C12P5/00 ,  C12P7/62

CPC分类号： C12N15/81 ,  C12N9/0006 ,  C12N9/0008 ,  C12N9/1025 ,  C12N9/1029 ,  C12N9/93 ,  C12P5/007 ,  C12P7/16 ,  C12P7/625 ,  C12Y101/01002 ,  C12Y102/01004 ,  C12Y203/01009 ,  C12Y602/01001 ,  Y02E50/10

摘要： The present invention relates to yeast cells producing high levels of acetoacetyl-CoA. It also relates to a method for making such yeast cells and to the use of such yeast cells in a method for producing acetyl-CoA derived products.

摘要翻译： 本发明涉及产生高含量乙酰乙酰辅酶A的酵母细胞。 本发明还涉及制备这种酵母细胞的方法以及在制备乙酰辅酶A衍生产物的方法中使用这种酵母细胞。

公开(公告)号：US20080095883A1

公开(公告)日：2008-04-24

申请号：US11952640

申请日：2007-12-07

申请人： Gitte Budolfsen ,  Morten Jensen ,  Hans Heldt-Hansen ,  Mary Stringer ,  Lene Lange

发明人： Gitte Budolfsen ,  Morten Jensen ,  Hans Heldt-Hansen ,  Mary Stringer ,  Lene Lange

IPC分类号： A21D8/04 ,  C12N9/82 ,  A23J3/20

CPC分类号： A21D8/042 ,  A23L5/25 ,  A23L7/117 ,  A23L19/19 ,  C12N9/82 ,  C12P1/00 ,  C12Y101/01118 ,  C12Y101/01119 ,  C12Y101/01124 ,  C12Y101/01147 ,  C12Y101/01148 ,  C12Y101/03009 ,  C12Y101/9901 ,  C12Y101/99011 ,  C12Y101/99018 ,  C12Y101/99028 ,  C12Y102/01003 ,  C12Y102/01004 ,  C12Y102/01005 ,  C12Y104/03002 ,  C12Y110/03002 ,  C12Y111/01007 ,  C12Y301/03004 ,  C12Y301/03005 ,  C12Y304/13018 ,  C12Y305/01001 ,  C12Y305/01002 ,  C12Y305/01026 ,  C12Y305/01043 ,  C12Y305/01052

摘要： The formation of acrylamide during heat treatment in the production of a food product is reduced by treating the raw material with an enzyme before the heat treatment. The enzyme is capable of reacting on asparagine or glutamine (optionally substituted) as a substrate or is a laccase or a peroxidase.

摘要翻译： 通过在热处理前用酶处理原料，可以减少在食品生产过程中热处理过程中丙烯酰胺的形成。 该酶能够对天冬酰胺或谷氨酰胺（任选取代）作为底物或是漆酶或过氧化物酶进行反应。

公开(公告)号：US12006523B2

公开(公告)日：2024-06-11

申请号：US17545616

申请日：2021-12-08

申请人： Braskem S.A.

发明人： Iuri Estrada Gouvea ,  Paulo Moises Raduan Alexandrino

IPC分类号： C12P17/04 ,  C07D307/68 ,  C12N1/21 ,  C12N9/02 ,  C12N9/04 ,  C12N9/08 ,  C12N9/16 ,  C12N9/88

CPC分类号： C12P17/04 ,  C07D307/68 ,  C12N9/0006 ,  C12N9/0008 ,  C12N9/0065 ,  C12N9/16 ,  C12N9/88 ,  C12Y101/01 ,  C12Y102/01 ,  C12Y101/01001 ,  C12Y101/03 ,  C12Y102/01003 ,  C12Y102/01004 ,  C12Y102/01005 ,  C12Y207/01 ,  C12Y301/03 ,  C12Y402/03

摘要： The present disclosure provides recombinant microorganisms and methods for the production of 4-HMF, 2,4-furandimethanol, furan-2,4-dicarbaldehyde, 4-(hydroxymethyl)furoic acid, 2-formylfuran-4-carboxylate, 4-formylfuran-2-carboxylate, and/or 2,4-FDCA from a carbon source. The method provides for engineered microorganisms that express endogenous and/or exogenous nucleic acid molecules that catalyze the conversion of a carbon source into 4-HMF, 2,4-furandimethanol, furan-2,4-dicarbaldehyde, 4-(hydroxymethyl)furoic acid, 2-formylfuran-4-carboxylate, 4-formylfuran-2-carboxylate, and/or 2,4-FDCA. The disclosure further provides methods of producing polymers derived from 4-HMF, 2,4-furandimethanol, furan-2,4-dicarbaldehyde, 4-(hydroxymethyl)furoic acid, 2-formylfuran-4-carboxylate, 4-formylfuran-2-carboxylate, and/or 2,4-FDCA.

公开(公告)号：US09670494B2

公开(公告)日：2017-06-06

申请号：US14370959

申请日：2012-12-17

申请人： Jens Nielsen ,  Verena Siewers ,  Yun Chen ,  Laurent Daviet ,  Michel Schalk

发明人： Jens Nielsen ,  Verena Siewers ,  Yun Chen ,  Laurent Daviet ,  Michel Schalk

IPC分类号： C12P7/16 ,  C12N9/90 ,  C12N15/81 ,  C12N9/04 ,  C12N9/10 ,  C12N9/00 ,  C12P5/00 ,  C12P7/62 ,  C12N9/02

CPC分类号： C12N15/81 ,  C12N9/0006 ,  C12N9/0008 ,  C12N9/1025 ,  C12N9/1029 ,  C12N9/93 ,  C12P5/007 ,  C12P7/16 ,  C12P7/625 ,  C12Y101/01002 ,  C12Y102/01004 ,  C12Y203/01009 ,  C12Y602/01001 ,  Y02E50/10

摘要： The present invention relates to yeast cells producing high levels of acetoacetyl-CoA. It also relates to a method for making such yeast cells and to the use of such yeast cells in a method for producing acetyl-CoA derived products.

公开(公告)号：US08507246B2

公开(公告)日：2013-08-13

申请号：US13352511

申请日：2012-01-18

申请人： Gitte Budolfsen ,  Morten Tovborg Jensen ,  Hans Peter Heldt-Hansen ,  Mary Ann Stringer

发明人： Gitte Budolfsen ,  Morten Tovborg Jensen ,  Hans Peter Heldt-Hansen ,  Mary Ann Stringer

IPC分类号： C12N9/82 ,  C12N9/02 ,  C12P1/00 ,  C07K1/00 ,  C08B37/00 ,  A21D2/00 ,  C13K1/06 ,  A23F3/00 ,  A23F3/16 ,  A23B4/12 ,  C07H21/04

CPC分类号： A21D8/042 ,  A23L5/25 ,  A23L7/117 ,  A23L19/19 ,  C12N9/82 ,  C12P1/00 ,  C12Y101/01118 ,  C12Y101/01119 ,  C12Y101/01124 ,  C12Y101/01147 ,  C12Y101/01148 ,  C12Y101/03009 ,  C12Y101/9901 ,  C12Y101/99011 ,  C12Y101/99018 ,  C12Y101/99028 ,  C12Y102/01003 ,  C12Y102/01004 ,  C12Y102/01005 ,  C12Y104/03002 ,  C12Y110/03002 ,  C12Y111/01007 ,  C12Y301/03004 ,  C12Y301/03005 ,  C12Y304/13018 ,  C12Y305/01001 ,  C12Y305/01002 ,  C12Y305/01026 ,  C12Y305/01043 ,  C12Y305/01052

摘要： The formation of acrylamide during heat treatment in the production of a food product is reduced by treating the raw material with an enzyme before the heat treatment. The enzyme is capable of reacting on asparagine or glutamine (optionally substituted) as a substrate or is a laccase or a peroxidase.

摘要翻译： 通过在热处理前用酶处理原料，可以减少在食品生产过程中热处理过程中丙烯酰胺的形成。 该酶能够对天冬酰胺或谷氨酰胺（任选取代）作为底物或是漆酶或过氧化物酶进行反应。

公开(公告)号：US5914257A

公开(公告)日：1999-06-22

申请号：US987260

申请日：1992-12-07

申请人： Masahiro Fukaya ,  Kenji Tayama ,  Toshimi Tamaki ,  Haruko Izumo ,  Hajime Okumura ,  Yoshiya Kawamura

发明人： Masahiro Fukaya ,  Kenji Tayama ,  Toshimi Tamaki ,  Haruko Izumo ,  Hajime Okumura ,  Yoshiya Kawamura

IPC分类号： C12N1/21 ,  C12N9/02 ,  C12N9/04 ,  C12N15/09 ,  C12N15/53 ,  C12P7/54 ,  C12R1/02

CPC分类号： C12N9/0008 ,  C12P7/54 ,  C12Y102/01003 ,  C12Y102/01004 ,  C12Y102/01005

摘要： This invention relates to the structural gene for the membrane-bound aldehyde dehydrogenase derived from microorganisms belonging to the genus Acetobacter, said structural gene having a molecular size of about 3.6 Kb and having a restriction enzyme cleavage map as shown in FIG. 1; to a plasmid containing said structural gene; to an acetic acid bacterium transformed by said plasmid; and to an acetic acid fermentation process using said transformant.

摘要翻译： 本发明涉及来自属于醋杆菌属的微生物的膜结合醛脱氢酶的结构基因，所述结构基因具有约3.6Kb的分子大小，并具有如图1所示的限制酶切割图。 1; 涉及含有所述结构基因的质粒; 向由所述质粒转化的乙酸细菌; 以及使用所述转化体的乙酸发酵方法。

公开(公告)号：US20180100169A1

公开(公告)日：2018-04-12

申请号：US15564919

申请日：2015-04-07

申请人： METABOLIC EXPLORER

发明人： Philippe SOUCAILLE ,  Gwénaëlle BESTEL-CORRE ,  Laurence DUMON-SEIGNOVERT

IPC分类号： C12P7/42 ,  C12N9/04 ,  C07C59/10 ,  C07C31/22 ,  C07C47/19 ,  C12R1/19

CPC分类号： C12P7/42 ,  C07C31/22 ,  C07C47/19 ,  C07C59/10 ,  C12N9/0004 ,  C12N9/0006 ,  C12P7/18 ,  C12R1/07 ,  C12R1/145 ,  C12R1/19 ,  C12Y101/01001 ,  C12Y102/01003 ,  C12Y102/01004 ,  C12Y102/03001

摘要： The present invention relates to a genetically modified microorganism for the production of 2,4-dihydroxybutyrate, by metabolic transformation of xylose via the 1,2,4-butanetriol intermediate. The invention also relates to a method for the production of 2,4-dihydroxybutyrate by culturing said genetically modified microorganism in a fermentation medium and recovering 2,4-DHB from said medium.

公开(公告)号：US20160333380A1

公开(公告)日：2016-11-17

申请号：US15153492

申请日：2016-05-12

申请人： Samsung Electronics Co., Ltd.

发明人： Soonchun Chung ,  Jinha Kim ,  Kwangmyung Cho

IPC分类号： C12P7/42 ,  C12N15/52 ,  C12N9/88 ,  C12N9/02 ,  C12N15/81 ,  C12N9/04

CPC分类号： C12P7/42 ,  C12N9/0006 ,  C12N9/0008 ,  C12N9/88 ,  C12N15/52 ,  C12N15/81 ,  C12P7/56 ,  C12Y101/01001 ,  C12Y101/01008 ,  C12Y101/01027 ,  C12Y101/01028 ,  C12Y101/01094 ,  C12Y101/02003 ,  C12Y101/02004 ,  C12Y101/05003 ,  C12Y102/01004 ,  C12Y102/0101 ,  C12Y401/01001

摘要： Provided are a genetically engineered yeast cell having increased activity of SUL1, STR3, HXT7, ERR1, GRX8, MXR1, GRE1, MRK1, AAD10 or a combination thereof, compared to a parent cell, and also having acid tolerance, a method of preparing the same, and a method of producing lactate using the same.

摘要翻译： 提供了与亲本细胞相比，具有增加的SUL1，STR3，HXT7，ERR1，GRX8，MXR1，GRE1，MRK1，AAD10或其组合的活性的遗传工程酵母细胞，并且还具有耐酸性，制备 相同，以及使用其制造乳酸盐的方法。

公开(公告)号：US20150361464A1

公开(公告)日：2015-12-17

申请号：US14740933

申请日：2015-06-16

申请人： INVISTA North America S.á r.l.

发明人： Adriana Leonora Botes ,  Alex Van Eck Conradie

IPC分类号： C12P13/00 ,  C12P7/44 ,  C12P7/42 ,  C12N9/10 ,  C12N9/88 ,  C12N9/06 ,  C12N9/80 ,  C12N9/02 ,  C07C229/08 ,  C12P7/18

CPC分类号： C12N9/0008 ,  C07C229/08 ,  C12N9/0022 ,  C12N9/0069 ,  C12N9/1096 ,  C12N9/80 ,  C12N9/88 ,  C12P7/18 ,  C12P7/42 ,  C12P7/46 ,  C12P13/005 ,  C12Y102/01003 ,  C12Y102/01004 ,  C12Y104/03021 ,  C12Y113/12002 ,  C12Y206/01 ,  C12Y305/0103 ,  C12Y401/01

摘要： This document describes biochemical pathways for producing glutaric acid, 5-aminopentanoic acid, 5-hydroxypentanoic acid or 1,5-pentanediol by forming one or two terminal functional groups, comprised of carboxyl, amine or hydroxyl group, in a C5 backbone substrate such as cadaverine or 5-aminopentanamide.

摘要翻译： 该文献描述了通过在C5主链基质中形成一个或两个由羧基，胺或羟基组成的末端官能团来生产戊二酸，5-氨基戊酸，5-羟基戊酸或1,5-戊二醇的生化途径，例如 尸胺或5-氨基戊酰胺。