Hydrodynamic Focusing Devices
    1.
    发明申请
    Hydrodynamic Focusing Devices 失效
    流体动力聚焦装置

    公开(公告)号:US20040266022A1

    公开(公告)日:2004-12-30

    申请号:US10609227

    申请日:2003-06-26

    IPC分类号: G01N001/10

    摘要: A micro-fluidic device containing a micro-fluidic inlet channel to convey a process flow, a plurality of micro-fluidic focusing channels to each convey one of a plurality of focusing flows, a focusing manifold coupled with the inlet channel at an inlet port thereof and with the plurality of focusing channels at a plurality of focusing channel ports thereof to focus the process flow by contacting and hydrodynamically impacting at least three sides of the process flow with the focusing flows, and a micro-fluidic outlet channel coupled with the focusing manifold at an outlet channel port to convey the combined focused process flow and focusing flow from the focusing manifold.

    摘要翻译: 一种微流体装置,其包含用于输送工艺流的微流体入口通道,多个微流体聚焦通道,每个输送多个聚焦流中的一个;聚焦歧管,其与入口通道在其入口端口处连接 并且多个聚焦通道在其多个聚焦通道端口处,以通过与聚焦流接触和流体动力地冲击处理流的至少三个侧面来聚焦工艺流程,以及与聚焦歧管耦合的微流体出口通道 在出口通道端口处传送来自聚焦歧管的组合的聚焦过程流和聚焦流。

    High-throughput purification process
    2.
    发明申请
    High-throughput purification process 审中-公开
    高通量净化工艺

    公开(公告)号:US20040241866A1

    公开(公告)日:2004-12-02

    申请号:US10869780

    申请日:2004-06-15

    IPC分类号: G01N001/10

    摘要: A component of a chemical mixture is isolated via a high-throughput purification process. An analytical retention time and corresponding analytical chromatographic parameters are determined for the component. Based on the analytical retention time and the corresponding analytical chromatographic parameters, preparative chromatographic parameters are determined to isolate the component at an accelerated retention time using a preparative column. The chemical mixture is eluted through the preparative column using the preparative chromatographic parameters, and the component is isolated at the accelerated retention time.

    摘要翻译: 化学混合物的组分通过高通量纯化方法分离。 确定组分的分析保留时间和相应的分析色谱参数。 基于分析保留时间和相应的分析色谱参数,确定制备色谱参数以使用制备柱在加速保留时间分离组分。 使用制备色谱参数将化学混合物通过制备柱洗脱,并且在加速保留时间分离组分。

    Method and apparatus for sample preparation in an automated discrete fluid sample analyzer
    3.
    发明申请
    Method and apparatus for sample preparation in an automated discrete fluid sample analyzer 有权
    自动离散液体样品分析仪中样品制备的方法和设备

    公开(公告)号:US20040219062A1

    公开(公告)日:2004-11-04

    申请号:US10426893

    申请日:2003-04-30

    IPC分类号: G01N001/10

    摘要: An automated discrete fluid sample analyzer includes a sample preparation module. The sample preparation module includes a well configured to receive a sample deposited by a pipettor and a sample preparation device in fluid communication with the well. The fluid sample is transferred from the well to the sample preparation device, and the sample preparation device prepares the fluid sample. The pipettor then aspirates the prepared fluid sample. The prepared fluid sample may be transferred from the sample preparation device back to the well, and the pipettor aspirates the prepared fluid sample from the well. In one embodiment, the sample preparation device includes a receptacle having a catalyst disposed therein. The catalyst may include a noble metal catalyst, such as cadmium. In another embodiment, the sample preparation device includes an ultraviolet lamp configured to apply ultraviolet light to the fluid sample. In yet another embodiment, the sample preparation device includes a heater configured to heat the fluid sample. In another aspect, a fluid sample is agitated to place more of the fluid sample in contact with the catalyst.

    摘要翻译: 自动离散流体样品分析仪包括样品制备模块。 样品制备模块包括良好配置以接收由移液器沉积的样品和与所述孔流体连通的样品制备装置。 流体样品从孔转移到样品制备装置,样品制备装置准备流体样品。 然后,移液器吸出制备的流体样品。 制备的流体样品可以从样品制备装置转移回井,并且移液器从井中吸出制备的流体样品。 在一个实施例中,样品制备装置包括其中布置有催化剂的容器。 催化剂可以包括贵金属催化剂,例如镉。 在另一个实施例中,样品制备装置包括配置成向流体样品施加紫外光的紫外线灯。 在另一个实施例中,样品制备装置包括配置成加热流体样品的加热器。 在另一方面,搅动流体样品以使更多的流体样品与催化剂接触。

    Sensor apparatus for in situ analysis of chemical and biological species
    6.
    发明申请
    Sensor apparatus for in situ analysis of chemical and biological species 审中-公开
    用于化学和生物物种原位分析的传感器装置

    公开(公告)号:US20040099066A1

    公开(公告)日:2004-05-27

    申请号:US10303522

    申请日:2002-11-25

    IPC分类号: G01N001/10

    摘要: An analytical system is provided which uses the kinetic energy of motion of the entire system to drive a fluid under analysis through the system. This is accomplished by use of a tethering system which is attached to the system. Various sensor detection systems may be used to analyze the sample collected within the confines of a sample isolation and concentration module contained within the system. Trace quantities of suspect materials may be detected or monitored by use of the instant system.

    摘要翻译: 提供了一种分析系统,其使用整个系统的运动动能来驱动通过系统分析的流体。 这通过使用连接到系统的系绳系统来实现。 可以使用各种传感器检测系统来分析在系统内包含的样品分离和浓缩模块的范围内收集的样品。 通过使用即时系统可以检测或监测痕量的可疑材料。

    Flow cell for optical analysis of a fluid
    9.
    发明申请
    Flow cell for optical analysis of a fluid 有权
    用于液体光学分析的流通池

    公开(公告)号:US20040080744A1

    公开(公告)日:2004-04-29

    申请号:US10282392

    申请日:2002-10-29

    发明人: Steven E. Hobbs

    IPC分类号: G01N001/10 G01N021/05

    摘要: A flow cell for performing optical analysis of a fluid is provided. The flow cell comprises a monolithic cell housing that defines a detection chamber, fluid inlet and outlet ports and illumination and detection ports. Optical fibers are inserted in the illumination and detection ports, thereby forming substantially fluid-tight seals. A flow cell may be press-fit against a microfluidic device, with fluid sealing aided by O-rings.

    摘要翻译: 提供了用于进行流体光学分析的流通池。 流动池包括限定检测室,流体入口和出口以及照明和检测端口的单体电池壳体。 光纤被插入到照明和检测端口中,从而形成基本上流体密封的密封。 流动池可以压配合微流体装置,流体密封由O形环辅助。

    High-speed liquid dispensing modules
    10.
    发明申请
    High-speed liquid dispensing modules 有权
    高速液体分配模块

    公开(公告)号:US20040076551A1

    公开(公告)日:2004-04-22

    申请号:US10657401

    申请日:2003-09-08

    IPC分类号: G01N001/10

    摘要: Liquid dispensing module and methods for dispensing a heated liquid onto a substrate. The dispensing module includes a dispenser body receiving liquid from a heated liquid distribution manifold and an actuator having a housing with an air piston movable in an air cavity and a solenoid valve for pressurizing the air cavity. Movement of the air piston controls a flow-regulating mechanism for selectively dispensing liquid from the dispenser body. A thermally insulating shield may be provided for reducing heat transfer from the manifold and/or dispenser body to the actuator so that the solenoid valve can be mounted directly to the housing and the effective volume of the air cavity can be reduced. The cycle time of the liquid dispensing module may be specified by selecting an initial volume of the air cavity and an effective valve flow coefficient for the actuator that characterizes the air flow to the air cavity.

    摘要翻译: 液体分配模块和用于将加热液体分配到基底上的方法。 分配模块包括从加热的液体分配歧管接收液体的分配器主体和具有可在空气腔中移动的空气活塞的壳体的致动器和用于加压空气腔的电磁阀。 空气活塞的移动控制用于选择性地从分配器主体分配液体的流量调节机构。 可以提供隔热屏蔽件,用于减少从歧管和/或分配器主体到致动器的热传递,使得电磁阀可以直接安装到壳体,并且可以减小空气腔的有效容积。 液体分配模块的循环时间可以通过选择空气腔的初始体积和用于表征到空气腔的气流的致动器的有效阀流量系数来指定。