-
公开(公告)号：WO2008055068A3
公开(公告)日：2009-03-05
申请号：PCT/US2007082668
申请日：2007-10-26
Applicant: METHYGENE INC , EN VIVO PHARMACEUTICALS INC , DEZIEL ROBERT , LEIT SILVANA , BEAULIEU PATRICK , CHANTIGNY YVES ANDRE , MANCUSO JOHN , TESSIER PIERRE , SHAPIRO GIDEON , CHESWORTH RICHARD , SMIL DAVID
Inventor： DEZIEL ROBERT , LEIT SILVANA , BEAULIEU PATRICK , CHANTIGNY YVES ANDRE , MANCUSO JOHN , TESSIER PIERRE , SHAPIRO GIDEON , CHESWORTH RICHARD , SMIL DAVID
IPC: C07D209/22 , A61K31/55 , A61K31/5513 , A61K31/553 , A61K31/554 , A61P43/00 , C07D209/70 , C07D221/12 , C07D223/26 , C07D225/08 , C07D239/28 , C07D239/34 , C07D239/42 , C07D243/14 , C07D243/24
CPC classification number: C07D498/04 , C07C259/06 , C07C259/10 , C07D209/02 , C07D209/08 , C07D209/52 , C07D209/94 , C07D221/12 , C07D223/16 , C07D223/20 , C07D223/22 , C07D223/24 , C07D223/26 , C07D223/28 , C07D225/08 , C07D239/28 , C07D239/34 , C07D239/42 , C07D243/24 , C07D243/38 , C07D265/38 , C07D267/14 , C07D267/18 , C07D267/20 , C07D279/22 , C07D279/26 , C07D281/16 , C07D285/36 , C07D291/08 , C07D295/155 , C07D313/12 , C07D401/14 , C07D403/04 , C07D403/14 , C07D413/06 , C07D413/12 , C07D471/04 , C07D471/08 , C07D471/14 , C07D487/04 , C07D487/08 , C07D487/14 , C07D491/08 , C07D495/04 , C07D513/04 , C07H13/10
Abstract: This invention relates to compounds for the inhibition of histone deacetylase. More particularly, the invention provides for compounds of formula (I) wherein (B), Q, J, L and Z are as defined in the specification.
Abstract translation: 本发明涉及抑制组蛋白脱乙酰酶的化合物。 更具体地，本发明提供式（I）的化合物，其中（B），Q，J，L和Z如说明书中所定义。
-
Patent Agency Ranking
公开(公告)号：WO2008122115A1
公开(公告)日：2008-10-16
申请号：PCT/CA2008/000631
申请日：2008-04-09
Applicant: METHYLGENE INC. , TESSIER, Pierre , LEIT, Silvana , SMIL, David , DÉZIEL, Robert , AJAMIAN, Alain , CHANTIGNY, Yves, Andre , DOMINGUEZ, Celia
Inventor： TESSIER, Pierre , LEIT, Silvana , SMIL, David , DÉZIEL, Robert , AJAMIAN, Alain , CHANTIGNY, Yves, Andre , DOMINGUEZ, Celia
IPC: C07C259/06 , A61K31/16 , A61K31/18 , A61K31/33 , C07C311/19 , C07C323/50 , C07D521/00
CPC classification number: C07D307/79 , C07C259/06 , C07C275/42 , C07C311/08 , C07C311/21 , C07C323/52 , C07D205/04 , C07D207/263 , C07D207/337 , C07D209/08 , C07D209/44 , C07D211/34 , C07D211/46 , C07D211/52 , C07D211/64 , C07D211/76 , C07D213/56 , C07D213/64 , C07D213/70 , C07D213/74 , C07D215/26 , C07D219/04 , C07D231/14 , C07D233/84 , C07D235/16 , C07D235/28 , C07D239/26 , C07D239/34 , C07D239/38 , C07D239/42 , C07D249/06 , C07D267/20 , C07D277/36 , C07D277/74 , C07D285/12 , C07D295/088 , C07D295/155 , C07D295/192 , C07D295/205 , C07D295/26 , C07D311/84 , C07D317/50 , C07D333/24 , C07D401/04 , C07D401/06 , C07D409/04 , C07D413/04 , C07D413/14 , C07D417/04 , C07D417/06 , C07D471/04 , C07D491/08 , C07D491/10 , C07D513/04
Abstract: This invention relates to compounds for the inhibition of histone deacetylase. More particularly, the invention provides for compounds of formula compounds of the Formula (I) and N-oxides, hydrates, solvates, pharmaceutically acceptable salts, prodrugs and complexes thereof, and racemic and scalemic mixtures, diastereomers and enantiomers thereof, wherein groups L, M, X and Y are as defined herein.
Abstract translation: 本发明涉及抑制组蛋白脱乙酰酶的化合物。 更具体地，本发明提供式（I）的式化合物及其N-氧化物，水合物，溶剂合物，药学上可接受的盐，前体药物和复合物的化合物及其外消旋和可饱和的混合物，非对映异构体和对映异构体，其中基团L， M，X和Y如本文所定义。
-
公开(公告)号：WO2008055068A8
公开(公告)日：2008-07-24
申请号：PCT/US2007082668
申请日：2007-10-26
Applicant: METHYGENE INC , EN VIVO PHARMACEUTICALS INC , DEZIEL ROBERT , LEIT SILVANA , BEAULIEU PATRICK , CHANTIGNY YVES ANDRE , MANCUSO JOHN , TESSIER PIERRE , SHAPIRO GIDEON , CHESWORTH RICHARD , SMIL DAVID
Inventor： DEZIEL ROBERT , LEIT SILVANA , BEAULIEU PATRICK , CHANTIGNY YVES ANDRE , MANCUSO JOHN , TESSIER PIERRE , SHAPIRO GIDEON , CHESWORTH RICHARD , SMIL DAVID
IPC: C07D223/26 , A61K31/55 , A61K31/554 , C07D243/24 , C07D267/20 , C07D281/16 , C07D291/08 , C07D401/14 , C07D471/04
CPC classification number: C07D498/04 , C07C259/06 , C07C259/10 , C07D209/02 , C07D209/08 , C07D209/52 , C07D209/94 , C07D221/12 , C07D223/16 , C07D223/20 , C07D223/22 , C07D223/24 , C07D223/26 , C07D223/28 , C07D225/08 , C07D239/28 , C07D239/34 , C07D239/42 , C07D243/24 , C07D243/38 , C07D265/38 , C07D267/14 , C07D267/18 , C07D267/20 , C07D279/22 , C07D279/26 , C07D281/16 , C07D285/36 , C07D291/08 , C07D295/155 , C07D313/12 , C07D401/14 , C07D403/04 , C07D403/14 , C07D413/06 , C07D413/12 , C07D471/04 , C07D471/08 , C07D471/14 , C07D487/04 , C07D487/08 , C07D487/14 , C07D491/08 , C07D495/04 , C07D513/04 , C07H13/10
Abstract: This invention relates to compounds for the inhibition of histone deacetylase. More particularly, the invention provides for compounds of formula (I) wherein (B), Q, J, L and Z are as defined in the specification.
-
公开(公告)号：WO2008055068A2
公开(公告)日：2008-05-08
申请号：PCT/US2007/082668
申请日：2007-10-26
Applicant: METHYGENE INC. , EN VIVO PHARMACEUTICALS, INC. , SHAPIRO, Gideon , MONCUSO, John , PIERRE, Tessier , LEIT, Silvana , DEZIEL, Robert , DAVID, Smil , RICHARD, Chesworth , CHANTIGNY, Yves, Andre , PATRICK, Beaulieu
Inventor： SHAPIRO, Gideon , MONCUSO, John , PIERRE, Tessier , LEIT, Silvana , DEZIEL, Robert , DAVID, Smil , RICHARD, Chesworth , CHANTIGNY, Yves, Andre , PATRICK, Beaulieu
CPC classification number: C07D498/04 , C07C259/06 , C07C259/10 , C07D209/02 , C07D209/08 , C07D209/52 , C07D209/94 , C07D221/12 , C07D223/16 , C07D223/20 , C07D223/22 , C07D223/24 , C07D223/26 , C07D223/28 , C07D225/08 , C07D239/28 , C07D239/34 , C07D239/42 , C07D243/24 , C07D243/38 , C07D265/38 , C07D267/14 , C07D267/18 , C07D267/20 , C07D279/22 , C07D279/26 , C07D281/16 , C07D285/36 , C07D291/08 , C07D295/155 , C07D313/12 , C07D401/14 , C07D403/04 , C07D403/14 , C07D413/06 , C07D413/12 , C07D471/04 , C07D471/08 , C07D471/14 , C07D487/04 , C07D487/08 , C07D487/14 , C07D491/08 , C07D495/04 , C07D513/04 , C07H13/10
Abstract: This invention relates to compounds for the inhibition of histone deacetylase. More particularly, the invention provides for compounds of formula (I) wherein (B), Q, J, L and Z are as defined in the specification.
Abstract translation: 本发明涉及抑制组蛋白脱乙酰酶的化合物。 更具体地，本发明提供式（I）的化合物，其中（B），Q，J，L和Z如说明书中所定义。
-
公开(公告)号：WO2006102760A1
公开(公告)日：2006-10-05
申请号：PCT/CA2006/000483
申请日：2006-03-31
Applicant: METHYLGENE INC. , LEIT DE MORADEI, Silvana, Marcela , TESSIER, Pierre , SMIL, David , WAHHAB, Amal , DÉZIEL, Robert , MANKU, Sukhdev , MANCUSO, John , THERRIEN, Eric , ALLAN, Martin , CHANTIGNY, Yves, Andre , AJAMIAN, Alain , BEAULIEU, Patrick
Inventor： LEIT DE MORADEI, Silvana, Marcela , TESSIER, Pierre , SMIL, David , WAHHAB, Amal , DÉZIEL, Robert , MANKU, Sukhdev , MANCUSO, John , THERRIEN, Eric , ALLAN, Martin , CHANTIGNY, Yves, Andre , AJAMIAN, Alain , BEAULIEU, Patrick
IPC: C07D417/04 , A61K31/18 , A61K31/166 , A61K31/195 , A61K31/34 , A61K31/404 , A61K31/4184 , A61K31/4192 , A61K31/426 , A61K31/427 , A61K31/433 , A61K31/44 , A61K31/4427 , A61K31/47 , A61K31/495 , A61K31/505 , C07C237/38 , C07C311/21 , C07C323/33 , C07C323/60 , C07D207/16 , C07D209/30 , C07D209/42 , C07D211/22 , C07D215/38 , C07D217/12 , C07D235/04 , C07D239/08 , C07D241/40 , C07D277/82 , C07D285/12 , C07D317/46 , C07D319/14 , C07D333/32 , C07D403/06 , C07D409/06 , C07D413/04
CPC classification number: C07D209/14 , C07C237/22 , C07C309/51 , C07C311/13 , C07C311/29 , C07C311/46 , C07C311/51 , C07C311/59 , C07C317/22 , C07C317/32 , C07C317/44 , C07C323/60 , C07C2601/14 , C07C2603/32 , C07D209/42 , C07D209/46 , C07D213/30 , C07D213/32 , C07D213/40 , C07D213/70 , C07D213/89 , C07D215/40 , C07D235/14 , C07D239/38 , C07D241/52 , C07D277/82 , C07D285/12 , C07D285/135 , C07D295/185 , C07D307/42 , C07D307/81 , C07D317/58 , C07D333/16 , C07D333/24 , C07D333/34 , C07D401/06 , C07D405/12 , C07D409/06 , C07D409/12
Abstract: This invention relates to compounds for the inhibition of histone deacetylase. More particularly, the invention provides for compounds of formula (I); wherein Y, L, Z, W, X, Q, R 1 , R 2 and R 3 are as defined in the specification.
Abstract translation: 本发明涉及抑制组蛋白脱乙酰酶的化合物。 更具体地，本发明提供式（I）的化合物; 其中Y，L，Z，W，X，Q，R 1，R 2和R 3均如说明书中所定义。
-
公开(公告)号：WO2004005229A1
公开(公告)日：2004-01-15
申请号：PCT/IB2003/002941
申请日：2003-06-25
Applicant: PFIZER PRODUCTS INC. , CHANTIGNY, Yves Andre , KLEINMAN, Edward, Fox , ROBINSON, Jr., Ralph, Pelton
IPC: C07C39/23
CPC classification number: C07D213/30 , C07C35/42 , C07C39/17 , C07C39/23 , C07C39/42 , C07C43/23 , C07C49/747 , C07C49/755 , C07C49/83 , C07C59/72 , C07C69/712 , C07C205/57 , C07C215/64 , C07C235/20 , C07C255/13 , C07C255/29 , C07C255/53 , C07C271/52 , C07C2603/26 , C07D213/40 , C07D257/04 , C07D271/06 , C07D277/24 , C07D295/088 , C07D295/185 , C07D413/06 , C07D413/12
Abstract: The present invention provides compounds of the formula wherein A is of the formula and X, Y, n, R 1 -R 25 are as described in the specification which are modulators of the glucocorticoid receptor and are thus useful for the treatment of animals requiring glucocorticoid receptor ágonist.therapy. Glucocorticoid-receptor modulators are useful in the treatment of certain inflammatory conditions.
Abstract translation: 本发明提供下式的化合物，其中A为下式且X，Y，n，R 1 -R 25如说明书中所述，其为糖皮质激素受体的调节剂，因此可用于治疗 的动物需要糖皮质激素受体ágonist.therapy。 糖皮质激素受体调节剂可用于治疗某些炎性疾病。
-
-
-
-
-
Search Results
6
records
(took 0.019 seconds)
