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    SYSTEMS, METHODS AND COMPUTER-ACCESSIBLE MEDIUM WHICH PROVIDE MICROSCOPIC IMAGES OF AT LEAST ONE ANATOMICAL STRUCTURE AT A PARTICULAR RESOLUTION
    3.
    发明申请
    SYSTEMS, METHODS AND COMPUTER-ACCESSIBLE MEDIUM WHICH PROVIDE MICROSCOPIC IMAGES OF AT LEAST ONE ANATOMICAL STRUCTURE AT A PARTICULAR RESOLUTION 有权
    系统，方法和计算机可访问介质，提供特定解决方案中至少一个解剖结构的微观图像

    公开(公告)号：US20110261366A1

    公开(公告)日：2011-10-27

    申请号：US13042230

    申请日：2011-03-07

    申请人： Guillermo J. Tearney ,  Brett E. Bouma ,  Joseph A. Gardecki ,  Linbo Liu

    发明人： Guillermo J. Tearney ,  Brett E. Bouma ,  Joseph A. Gardecki ,  Linbo Liu

    IPC分类号： G01B9/02

    CPC分类号： A61B5/0066 ,  A61B5/0044 ,  A61B5/0075 ,  A61B5/0084 ,  G01B9/02091 ,  G02B6/32

    摘要： Exemplary embodiments of systems and methods can be provided which can generate data associated with at least one portion of a sample. For example, at least one first radiation can be forwarded to the portion through at least one optical arrangement. At least one second radiation can be received from the portion which is based on the first radiation. Based on an interaction between the optical arrangement and the first radiation and/or the second radiation, the optical arrangement can have a first transfer function. Further, it is possible to forward at least one third radiation to the portion through such optical arrangement (or through another optical arrangement), and receive at least one fourth radiation from the portion which is based on the third radiation. Based on an interaction between the optical arrangement (or the other optical arrangement) and the third radiation and/or the fourth radiation, the optical arrangement (or the other optical arrangement) can have a second transfer function. The first transfer function can be at least partially different from the second transfer function. The data can be generated based on the second and fourth radiations.

    摘要翻译： 可以提供可以生成与样品的至少一部分相关联的数据的系统和方法的示例性实施例。 例如，可以通过至少一个光学布置将至少一个第一辐射转发到该部分。 可以从基于第一辐射的部分接收至少一个第二辐射。 基于光学布置和第一辐射和/或第二辐射之间的相互作用，光学装置可以具有第一传递函数。 此外，可以通过这种光学装置（或通过另一种光学装置）将至少一个第三辐射转发到该部分，并且从基于第三辐射的部分接收至少一个第四辐射。 基于光学布置（或另一个光学布置）与第三辐射和/或第四辐射之间的相互作用，光学布置（或另一个光学布置）可以具有第二传递函数。 第一传递函数可以至少部分地不同于第二传递函数。 可以基于第二和第四辐射来生成数据。

    Systems, methods and computer-accessible medium which provide microscopic images of at least one anatomical structure at a particular resolution
    4.
    发明授权
    Systems, methods and computer-accessible medium which provide microscopic images of at least one anatomical structure at a particular resolution 有权
    以特定分辨率提供至少一个解剖结构的微观图像的系统，方法和计算机可访问介质

    公开(公告)号：US08896838B2

    公开(公告)日：2014-11-25

    申请号：US13042278

    申请日：2011-03-07

    申请人： Guillermo J. Tearney ,  Brett E. Bouma ,  Joseph A. Gardecki ,  Linbo Liu

    发明人： Guillermo J. Tearney ,  Brett E. Bouma ,  Joseph A. Gardecki ,  Linbo Liu

    IPC分类号： G01B9/02 ,  A61B5/00

    CPC分类号： A61B5/0066 ,  A61B5/0044 ,  A61B5/0075 ,  A61B5/0084 ,  G01B9/02091 ,  G02B6/32

    摘要： Exemplary embodiments of probes, apparatus, systems and methods can be provided which provide at least one electro-magnetic radiation to at least one sample. For example, a plurality of axicon lenses can be provided which are configured to provide the electro-magnetic radiation(s) having at least partially annulus shape. In addition or alternatively, at least one optical arrangement can be provided which is configured to forward at least one radiation to the sample therethrough having at least partially circularly-symmetric pattern. For example, at least one first portion of the radiation transmitted through a circular section of the pattern can have an optical path-length that is different from an optical path-length of at least one second portion of the radiation transmitted through at least one other section of the pattern.

    摘要翻译： 可以提供探针，装置，系统和方法的示例性实施例，其向至少一个样品提供至少一个电磁辐射。 例如，可以提供多个旋转透镜，其构造成提供具有至少部分环形形状的电磁辐射。 另外或替代地，可以提供至少一个光学布置，其被配置为将至少一个辐射转发到具有至少部分圆对称图案的样品。 例如，透过图案的圆形部分的辐射的至少一个第一部分可以具有不同于透过至少一个其它的辐射的至少一个第二部分的光程长度的光程长度 部分图案。

    SYSTEMS, METHODS AND COMPUTER-ACCESSIBLE MEDIUM WHICH PROVIDE MICROSCOPIC IMAGES OF AT LEAST ONE ANATOMICAL STRUCTURE AT A PARTICULAR RESOLUTION
    5.
    发明申请
    SYSTEMS, METHODS AND COMPUTER-ACCESSIBLE MEDIUM WHICH PROVIDE MICROSCOPIC IMAGES OF AT LEAST ONE ANATOMICAL STRUCTURE AT A PARTICULAR RESOLUTION 有权
    系统，方法和计算机可访问介质，提供特定解决方案中至少一个解剖结构的微观图像

    公开(公告)号：US20110218403A1

    公开(公告)日：2011-09-08

    申请号：US13042278

    申请日：2011-03-07

    申请人： Guillermo J. Tearney ,  Brett E. Bouma ,  Joseph A. Gardecki ,  Linbo Liu

    发明人： Guillermo J. Tearney ,  Brett E. Bouma ,  Joseph A. Gardecki ,  Linbo Liu

    IPC分类号： A61B1/06

    CPC分类号： A61B5/0066 ,  A61B5/0044 ,  A61B5/0075 ,  A61B5/0084 ,  G01B9/02091 ,  G02B6/32

    摘要： Exemplary embodiments of probes, apparatus, systems and methods can be provided which provide at least one electro-magnetic radiation to at least one sample. For example, a plurality of axicon lenses can be provided which are configured to provide the electro-magnetic radiation(s) having at least partially annulus shape. In addition or alternatively, at least one optical arrangement can be provided which is configured to forward at least one radiation to the sample therethrough having at least partially circularly-symmetric pattern. For example, at least one first portion of the radiation transmitted through a circular section of the pattern can have an optical path-length that is different from an optical path-length of at least one second portion of the radiation transmitted through at least one other section of the pattern.

    摘要翻译： 可以提供探针，装置，系统和方法的示例性实施例，其向至少一个样品提供至少一个电磁辐射。 例如，可以提供多个旋转透镜，其构造成提供具有至少部分环形形状的电磁辐射。 另外或替代地，可以提供至少一个光学布置，其被配置为将至少一个辐射转发到具有至少部分圆对称图案的样品。 例如，透过图案的圆形部分的辐射的至少一个第一部分可以具有不同于透过至少一个其它的辐射的至少一个第二部分的光程长度的光程长度 部分图案。

    Systems, methods and computer-accessible medium which provide microscopic images of at least one anatomical structure at a particular resolution
    6.
    发明授权
    Systems, methods and computer-accessible medium which provide microscopic images of at least one anatomical structure at a particular resolution 有权
    以特定分辨率提供至少一个解剖结构的微观图像的系统，方法和计算机可访问介质

    公开(公告)号：US08804126B2

    公开(公告)日：2014-08-12

    申请号：US13042230

    申请日：2011-03-07

    申请人： Guillermo J. Tearney ,  Brett E. Bouma ,  Joseph A. Gardecki ,  Linbo Liu

    发明人： Guillermo J. Tearney ,  Brett E. Bouma ,  Joseph A. Gardecki ,  Linbo Liu

    IPC分类号： G01B9/02

    CPC分类号： A61B5/0066 ,  A61B5/0044 ,  A61B5/0075 ,  A61B5/0084 ,  G01B9/02091 ,  G02B6/32

    摘要： Exemplary embodiments of systems and methods can be provided which can generate data associated with at least one portion of a sample. For example, at least one first radiation can be forwarded to the portion through at least one optical arrangement. At least one second radiation can be received from the portion which is based on the first radiation. Based on an interaction between the optical arrangement and the first radiation and/or the second radiation, the optical arrangement can have a first transfer function. Further, it is possible to forward at least one third radiation to the portion through such optical arrangement (or through another optical arrangement), and receive at least one fourth radiation from the portion which is based on the third radiation. Based on an interaction between the optical arrangement (or the other optical arrangement) and the third radiation and/or the fourth radiation, the optical arrangement (or the other optical arrangement) can have a second transfer function. The first transfer function can be at least partially different from the second transfer function. The data can be generated based on the second and fourth radiations.

    摘要翻译： 可以提供可以生成与样品的至少一部分相关联的数据的系统和方法的示例性实施例。 例如，可以通过至少一个光学布置将至少一个第一辐射转发到该部分。 可以从基于第一辐射的部分接收至少一个第二辐射。 基于光学布置和第一辐射和/或第二辐射之间的相互作用，光学装置可以具有第一传递函数。 此外，可以通过这种光学装置（或通过另一种光学装置）将至少一个第三辐射转发到该部分，并且从基于第三辐射的部分接收至少一个第四辐射。 基于光学布置（或另一个光学布置）和第三辐射和/或第四辐射之间的相互作用，光学布置（或另一个光学布置）可以具有第二传递函数。 第一传递函数可以至少部分地不同于第二传递函数。 可以基于第二和第四辐射来生成数据。

    APPARATUS, COMPUTER-ACCESSIBLE MEDIUM AND METHOD FOR MEASURING CHEMICAL AND/OR MOLECULAR COMPOSITIONS OF CORONARY ATHEROSCLEROTIC PLAQUES IN ANATOMICAL STRUCTURES
    7.
    发明申请
    APPARATUS, COMPUTER-ACCESSIBLE MEDIUM AND METHOD FOR MEASURING CHEMICAL AND/OR MOLECULAR COMPOSITIONS OF CORONARY ATHEROSCLEROTIC PLAQUES IN ANATOMICAL STRUCTURES 审中-公开
    装置，计算机可接受的介质和​​测量化学和/或分子结构的冠状动脉造影剂在解剖结构中的方法

    公开(公告)号：US20090073439A1

    公开(公告)日：2009-03-19

    申请号：US12210979

    申请日：2008-09-15

    申请人： Guillermo J. Tearney ,  Brett E. Bouma ,  Jason T. Motz ,  Joseph A. Gardecki ,  Alexandra H. Chau

    发明人： Guillermo J. Tearney ,  Brett E. Bouma ,  Jason T. Motz ,  Joseph A. Gardecki ,  Alexandra H. Chau

    IPC分类号： G01N21/00 ,  G02B6/06 ,  G06G7/48

    CPC分类号： A61B5/0075 ,  A61B5/0084 ,  A61B5/02007

    摘要： Exemplary apparatus and method can be provided for controlling at least one electro-magnetic radiation. For example, it is possible to rotate and/or translate at least one optical waveguide. At least one of the optical waveguide(s) can receive a first radiation at a first wavelength and transmit the first radiation to at least one sample. Such optical waveguide and/or another optical waveguide may receive a second radiation at a second wavelength that is different from the first wavelength. For example, the second radiation may be produced based on an inelastic scattering of the first radiation. In addition, exemplary apparatus and method can be provided which can also be used to receive data associated with the second radiation, determine at least one characteristic of the at least one sample based on the data, and generate the image and/or the map of a portion of the arterial sample based on the at least one characteristic. Further, exemplary computer-accessible medium can be provided which includes a software arrangement thereon. When a processing arrangement executes the software arrangement, the processing arrangement is configured to modify at least one characteristic of an arrangement using certain procedures. These exemplary procedures include simulating at least one electro-magnetic radiation provided into and out of the arrangement, simulating an inelastic scattering radiation from at least one simulated sample, receiving the simulated inelastic scattering radiation into and out of the simulated arrangement, and determining a simulated characteristic of the simulated arrangement as a function of the simulated inelastic scattering radiation.

    摘要翻译： 可以提供示例性的装置和方法来控制至少一个电磁辐射。 例如，可以旋转和/或平移至少一个光波导。 至少一个光波导可以接收第一波长的第一辐射并将第一辐射传输到至少一个样本。 这种光波导和/或另一光波导可以接收与第一波长不同的第二波长的第二辐射。 例如，可以基于第一辐射的非弹性散射来产生第二辐射。 此外，可以提供示例性的装置和方法，其还可以用于接收与第二辐射相关联的数据，基于数据确定至少一个样本的至少一个特性，并且生成图像和/或 基于至少一个特征的动脉样本的一部分。 此外，可以提供示例性的计算机可访问介质，其中包括其上的软件布置。 当处理装置执行软件装置时，处理装置被配置为使用某些程序来修改装置的至少一个特性。 这些示例性程序包括模拟提供入和排出的至少一个电磁辐射，模拟来自至少一个模拟样本的非弹性散射辐射，将模拟的非弹性散射辐射接收到模拟装置中和从模拟装置中取出，以及确定模拟 作为模拟非弹性散射辐射的函数的模拟布置的特征。