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    System for providing fluid flow to nerve tissues
    1.
    发明授权
    System for providing fluid flow to nerve tissues 有权

    公开(公告)号：US11357904B2

    公开(公告)日：2022-06-14

    申请号：US16671460

    申请日：2019-11-01

    Applicant: KCI Licensing, Inc.

    Inventor： Larry D. Swain ,  Michael E. Manwaring ,  Braden King-fung Leung ,  Douglas A. Cornet

    IPC: A61M1/00 ,  A61F13/00 ,  A61B17/11

    Abstract: An apparatus and system for providing reduced pressure to a defect in a nerve is disclosed. The apparatus comprises a nerve conduit having a generally tubular shape that has walls including a luminal wall surrounding the tissue site to contain fluids within a luminal space between the tissue site to contain fluids within a luminal space between the tissue site and the luminal wall. The apparatus further comprises a manifold having a porous body and a connector for receiving reduced pressure, wherein the manifold is positioned within the luminal space adjacent the tissue site to distribute the reduced pressure to the defect. Additionally, a method for providing reduced pressure to a defect in a nerve is disclosed that includes implanting the nerve conduit and manifold at a site of damaged nerve tissue and applying a reduced pressure to the manifold thereby stimulating repair or regrowth of nerve tissue.

    System for providing fluid flow to nerve tissues
    7.
    发明授权
    System for providing fluid flow to nerve tissues 有权
    用于向神经组织提供流体流动的系统

    公开(公告)号：US08998934B2

    公开(公告)日：2015-04-07

    申请号：US14252664

    申请日：2014-04-14

    Applicant: KCI Licensing, Inc.

    Inventor： Larry D. Swain ,  Michael E. Manwaring ,  Douglas A. Cornet ,  Braden K. Leung

    IPC: A61B17/08 ,  A61F13/00 ,  A61B17/11 ,  A61M1/00

    CPC classification number: A61M1/0088 ,  A61B17/11 ,  A61B17/1128 ,  A61F13/00063 ,  A61F13/00068

    Abstract: Provided is an apparatus that includes a nerve conduit and a nested manifold for providing a reduced pressure. Also provided is a system that includes a source of reduced pressure, a nerve conduit and nested manifold, and a conduit for providing fluid communication between the manifold and the source of reduced pressure. Additionally provided is a method that includes implanting the above nerve conduit and manifold at a site of damaged nerve tissue and applying a reduced pressure to the manifold thereby stimulating repair or regrowth of nerve tissue.

    Abstract translation: 提供了一种装置，其包括用于提供减压的神经管道和嵌套歧管。 还提供了包括减压源，神经管道和嵌套歧管的系统，以及用于在歧管和减压源之间提供流体连通的导管。 另外提供了一种方法，其包括将上述神经导管和歧管植入损伤的神经组织的部位，并将减压施加到歧管，从而刺激神经组织的修复或再生长。

    Tissue roll scaffolds
    8.
    发明授权
    Tissue roll scaffolds 有权

    公开(公告)号：US10155074B2

    公开(公告)日：2018-12-18

    申请号：US14811355

    申请日：2015-07-28

    Applicant: KCI Licensing, Inc.

    Inventor： Larry D. Swain ,  Michael E. Manwaring ,  Douglas A. Cornet ,  Braden King-fung Leung

    IPC: A61M1/00 ,  A61B17/11 ,  A61F13/00

    Abstract: An apparatus and system for treating a wound having a cavity is disclosed. The apparatus has a scaffold including a scaffold lamina and a tissue lamina wherein the scaffold lamina forms a laminate in fluid communication with the tissue lamina. The laminate is rolled into a generally cylindrical shape having two end surfaces. The apparatus further includes a manifold having a port for coupling to a source of reduced pressure and that is positioned in fluid communication with the scaffold to provide reduced pressure to the scaffold lamina and the wound. A method for treating a wound having a cavity is also disclosed and includes positioning a scaffold lamina adjacent a tissue lamina to form a laminate in fluid communication with the tissue lamina, rolling the laminate into a generally cylindrical shape having two end surfaces, and positioning the scaffold within the cavity of the wound.

    Activation of bone and cartilage formation
    9.
    发明授权
    Activation of bone and cartilage formation 有权
    激活骨和软骨形成

    公开(公告)号：US09271837B2

    公开(公告)日：2016-03-01

    申请号：US14523004

    申请日：2014-10-24

    Applicant: KCI Licensing, Inc.

    Inventor： Larry D. Swain

    IPC: A61M1/00 ,  A61F2/30 ,  A61F13/00

    CPC classification number: A61F2/30771 ,  A61F13/00017 ,  A61F13/00025 ,  A61F2002/30062 ,  A61F2002/30838 ,  A61F2002/3092 ,  A61F2002/3093 ,  A61F2013/00357 ,  A61M1/008 ,  A61M1/0088 ,  A61M2210/02

    Abstract: Provided is a method of activating osteogenic or chondrogenic activity at a site in a subject in need thereof. Also provided is a method of treating a bone or cartilage defect in a subject. Additionally, the use of a reduced pressure apparatus for treating a bone or cartilage defect adjacent to dura mater, periosteum, or endosteum is provided. Further provided is a composition for treating a bone or cartilage defect. Also, the use of a reduced pressure apparatus and a biocompatible scaffold for the manufacture of a composition for treating a bone or cartilage defect adjacent to dura mater, periosteum or endosteum is provided.

    Abstract translation: 提供了在有需要的受试者的部位活化成骨或软骨形成活性的方法。 还提供了治疗受试者的骨或软骨缺损的方法。 另外，提供了使用用于治疗邻近硬膜，骨膜或内皮的骨或软骨缺损的减压装置。 还提供了用于治疗骨或软骨缺损的组合物。 此外，提供了使用减压装置和生物相容性支架来制造用于治疗邻近硬膜，骨膜或内皮的骨或软骨缺损的组合物。

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