Hexahydropyrrolo[3,4-b]pyrrole derivatives, preparation methods and pharmaceutical uses thereof
    92.
    发明授权
    Hexahydropyrrolo[3,4-b]pyrrole derivatives, preparation methods and pharmaceutical uses thereof 有权
    六氢吡咯并[3,4-b]吡咯衍生物,其制备方法和药物用途

    公开(公告)号:US08785477B2

    公开(公告)日:2014-07-22

    申请号:US13685454

    申请日:2012-11-26

    CPC classification number: C07D487/04

    Abstract: Hexahydropyrrolo[3,4-b]pyrrole derivatives, preparation methods and pharmaceutical uses thereof are provided. Specifically, dipeptidyl peptidase IV inhibitors presented by following formula (I) are provided. Such compounds can be used for treating or preventing the diseases associated with dipeptidyl peptidase IV, such as diabetes, obesity and hyperlipemia. The compounds presented by formula (I) and pharmaceutically acceptable salts thereof, a method for preparing a pharmaceutical composition thereof and their uses in the manufacture of medicaments for treating or preventing the disease associated with dipeptidyl peptidase IV are provided.

    Abstract translation: 提供了六氢吡咯并[3,4-b]吡咯衍生物,其制备方法和药物用途。 具体地,提供了由下式(I)表示的二肽基肽酶IV抑制剂。 这些化合物可用于治疗或预防与二肽基肽酶IV相关的疾病,如糖尿病,肥胖症和高脂血症。 提供式(I)化合物及其药学上可接受的盐,其药物组合物的制备方法及其在制备用于治疗或预防与二肽基肽酶IV相关的疾病的药物中的用途。

    Automatically triggering predictions in recommendation systems based on an activity-probability threshold
    93.
    发明授权
    Automatically triggering predictions in recommendation systems based on an activity-probability threshold 有权
    基于活动概率阈值自动触发推荐系统中的预测

    公开(公告)号:US08732097B2

    公开(公告)日:2014-05-20

    申请号:US13402751

    申请日:2012-02-22

    CPC classification number: G06Q10/04 G06Q30/02

    Abstract: A recommender system determines a probability threshold for an activity-prediction model, and uses the probability threshold to predict whether a user is performing a target activity. To determine the probability threshold, the system computes a set of activity probabilities based on contextual information for a set of historical activities, and based on an activity-prediction model for a target activity. The system then compares a set of probability thresholds with the set of activity probabilities to determine a prediction success rate for each probability threshold. The system computes a utility score for each probability threshold based on the prediction success rates and a utility function, and selects a probability threshold whose utility score is optimal amongst the utility scores of the set of thresholds and greater than or equal to a baseline utility score. The system then assigns the probability threshold to the activity-prediction model.

    Abstract translation: 推荐系统确定活动预测模型的概率阈值,并使用概率阈值来预测用户是否正在执行目标活动。 为了确定概率阈值,系统基于一组历史活动的上下文信息,并且基于目标活动的活动预测模型来计算一组活动概率。 然后,系统将一组概率阈值与活动概率集合进行比较,以确定每个概率阈值的预测成功率。 该系统基于预测成功率和效用函数来计算每个概率阈值的效用得分,并且选择一个概率阈值,其效用评分在阈值集合的效用评分之间是最佳的,并且大于或等于基准效用得分 。 系统然后将概率阈值分配给活动预测模型。

    Method for revamping an HF or sulphuric acid alkylation unit
    94.
    发明授权
    Method for revamping an HF or sulphuric acid alkylation unit 有权
    改造HF或硫酸烷基化单元的方法

    公开(公告)号:US08692048B2

    公开(公告)日:2014-04-08

    申请号:US13388507

    申请日:2010-08-05

    CPC classification number: C07C2/58 C07C2531/14 C07C9/16

    Abstract: The present invention provides a method for revamping an HF or sulphuric acid alkylation unit to an ionic liquid alkylation unit, wherein the HF or sulphuric acid alkylation unit comprise at least: —a reactor unit for contacting catalyst and hydrocarbon reactants; —a separator unit for separating a reactor effluent into a catalyst phase and an alkylate-comprising hydrocarbon phase; —a fractionator unit for fractionating the alkylate-comprising hydrocarbon phase into at least one stream comprising alkylate; and which method includes: —providing a second separator unit suitable for the separation of solids from liquids downstream of the reactor unit suitable to reduce the solids content in at least part of the reactor effluent.

    Abstract translation: 本发明提供了将HF或硫酸烷基化单元改性为离子液体烷基化单元的方法,其中HF或硫酸烷基化单元至少包括: - 用于使催化剂和烃反应物接触的反应器单元; - 用于将反应器流出物分离成催化剂相和含烷基化物烃相的分离器单元; - 用于将含烷基化物烃相分级成至少一种包含烷基化物的流的分馏器单元; 并且哪种方法包括: - 提供适合于从反应器单元下游的液体中分离固体的第二分离器单元,其适于减少至少部分反应器流出物中的固体含量。

    PERFORMANCE-EFFICIENT SYSTEM AND METHOD FOR SAMPLING USERS FOR POPULATION-CENTRIC ACTIVITY MODELING
    95.
    发明申请
    PERFORMANCE-EFFICIENT SYSTEM AND METHOD FOR SAMPLING USERS FOR POPULATION-CENTRIC ACTIVITY MODELING 有权
    用于人口中心活动建模的采样效能系统和方法

    公开(公告)号:US20130262216A1

    公开(公告)日:2013-10-03

    申请号:US13436348

    申请日:2012-03-30

    CPC classification number: G06Q30/0631 G06Q30/02

    Abstract: A performance-efficient activity-modeling system generates a group-activity model for a population group using information from an optimal subset of users of the population group. During operation, the system computes utility scores for a set of users based on a utility-scoring function, such that a respective utility score indicates a usefulness or penalty of collecting a corresponding user's contextual information. The system then selects, from the set of users, a subset of users with highest utility scores, and receives user information from each of the selected users. The system generates the group-activity model based on the user information received from the selected users.

    Abstract translation: 一个高性能的活动建模系统使用来自群体组的最佳用户子集的信息为群体组生成群体活动模型。 在操作期间,系统基于效用评分函数计算一组用户的效用评分,使得相应的效用评分指示收集相应用户的上下文信息的有用性或惩罚。 然后,系统从用户组中选择具有最高实用程度分数的用户的子集,并且从每个所选择的用户接收用户信息。 系统基于从所选用户接收的用户信息生成组活动模型。

    HEXAHYDROPYRROLO[3,4-b]PYRROLE DERIVATIVES, PREPARATION METHODS AND PHARMACEUTICAL USES THEREOF
    96.
    发明申请
    HEXAHYDROPYRROLO[3,4-b]PYRROLE DERIVATIVES, PREPARATION METHODS AND PHARMACEUTICAL USES THEREOF 有权
    十氢吡咯并[3,4-b]吡咯烷酮衍生物,其制备方法及其药物用途

    公开(公告)号:US20130178500A1

    公开(公告)日:2013-07-11

    申请号:US13685454

    申请日:2012-11-26

    CPC classification number: C07D487/04

    Abstract: Hexahydropyrrolo[3,4-b]pyrrole derivatives, preparation methods and pharmaceutical uses thereof are provided. Specifically, dipeptidyl peptidase IV inhibitors presented by following formula (I) are provided. Such compounds can be used for treating or preventing the diseases associated with dipeptidyl peptidase IV, such as diabetes, obesity and hyperlipemia. The compounds presented by formula (I) and pharmaceutically acceptable salts thereof, a method for preparing a pharmaceutical composition thereof and their uses in the manufacture of medicaments for treating or preventing the disease associated with dipeptidyl peptidase IV are provided.

    Abstract translation: 提供了六氢吡咯并[3,4-b]吡咯衍生物,其制备方法和药物用途。 具体地,提供了由下式(I)表示的二肽基肽酶IV抑制剂。 这些化合物可用于治疗或预防与二肽基肽酶IV相关的疾病,如糖尿病,肥胖症和高脂血症。 提供式(I)化合物及其药学上可接受的盐,其药物组合物的制备方法及其在制备用于治疗或预防与二肽基肽酶IV相关的疾病的药物中的用途。

    ON-DEMAND STORAGE SYSTEM ENERGY SAVINGS
    97.
    发明申请
    ON-DEMAND STORAGE SYSTEM ENERGY SAVINGS 有权
    需求存储系统能源节约

    公开(公告)号:US20130013943A1

    公开(公告)日:2013-01-10

    申请号:US13562626

    申请日:2012-07-31

    CPC classification number: G06F1/3209 G06F1/3203

    Abstract: Embodiments of the invention relate to dynamic power management of storage volumes and disk arrays in a storage subsystem to mitigate loss of performance resulting from the power management. The volumes and arrays are prioritized, and in real-time power is selectively reduced in response to both the prioritization and an energy savings goal. A feedback loop is provided to dynamically measure associated power gain based upon a lowering of power consumption, and device selection may be adjusted based upon received feedback.

    Abstract translation: 本发明的实施例涉及存储子系统中的存储卷和磁盘阵列的动态功率管理,以减轻由电源管理产生的性能损失。 音量和阵列被优先考虑,并且实时功率被选择性地降低以响应优先级和节能目标。 提供反馈回路以基于功率消耗的降低来动态地测量相关联的功率增益,并且可以基于接收到的反馈来调整设备选择。

    METHODS FOR REGENERATING AND MAINTAINING ACTIVITY OF IONIC LIQUID CATALYST AND PRODUCING ALKYLATE
    98.
    发明申请
    METHODS FOR REGENERATING AND MAINTAINING ACTIVITY OF IONIC LIQUID CATALYST AND PRODUCING ALKYLATE 审中-公开
    再生和维持离子液体催化剂活性和生产烷基酸的方法

    公开(公告)号:US20120283500A1

    公开(公告)日:2012-11-08

    申请号:US13383946

    申请日:2010-07-15

    Abstract: Disclosed is a method for regenerating and maintaining the activity of an ionic liquid catalyst, which comprises supplying hydrogen halide or halogenated hydrocarbon to the acidic ionic liquid catalyst or alkylation materials during alkylation reaction, wherein said ionic liquid catalyst is used to catalyze alkylation of C4 alkene and alkane. Disclosed is also a method for producing alkylate by alkylation reaction, which comprises supplying hydrogen halide or halogenated hydrocarbon to the acidic ionic liquid catalyst or reaction materials during said alkylation reaction. The method can prolong the service life of the acidic ionic liquid catalyst, does not influence the quality of the alkylate, and has simple operation. The processed amount of materials may be 1000 times more than the used amount of the ionic liquid.

    Abstract translation: 公开了一种用于再生和保持离子液体催化剂的活性的方法,其包括在烷基化反应期间向酸性离子液体催化剂或烷基化材料供应卤化氢或卤代烃,其中所述离子液体催化剂用于催化C4烯烃的烷基化 和烷烃。 还公开了通过烷基化反应制备烷基化物的方法,其包括在所述烷基化反应期间向酸性离子液体催化剂或反应物质供应卤化氢或卤代烃。 该方法可延长酸性离子液体催化剂的使用寿命,不影响烷基化物质,操作简单。 处理量的材料可以是使用量的离子液体的1000倍。

    Condenser microphone
    99.
    发明授权
    Condenser microphone 有权
    冷凝器麦克风

    公开(公告)号:US08265309B2

    公开(公告)日:2012-09-11

    申请号:US12567763

    申请日:2009-09-26

    Applicant: Rui Zhang

    Inventor: Rui Zhang

    CPC classification number: H04R19/005 H04R19/04

    Abstract: A condenser microphone is disclosed. The condenser microphone includes a substrate having a cavity, a supporting member connected to the substrate, and a diaphragm isolated to the supporting member. The supporting member has a periphery portion and a plurality of stationary electrodes extending from the periphery portion to a center of the supporting member. The diaphragm has a vibrating member and a sustaining member connected to the vibrating member and the vibrating member defines a plurality of movable electrodes protruding from a periphery of the vibrating member. Each of the movable electrodes is located between two adjacent stationary electrodes and each of the stationary electrodes is located between two adjacent two movable electrodes.

    Abstract translation: 公开了一种电容麦克风。 电容麦克风包括具有空腔的基板,连接到基板的支撑构件和隔离到支撑构件的隔膜。 支撑构件具有周边部分和从周边部分延伸到支撑构件的中心的多个固定电极。 隔膜具有振动构件和与振动构件连接的保持构件,振动构件限定从振动构件的周边突出的多个可动电极。 每个可移动电极位于两个相邻的固定电极之间,并且每个固定电极位于两个相邻的两个可移动电极之间。

    Method and system for distinctively displaying selected floor with sufficient details in a three-dimensional building model
    100.
    发明授权
    Method and system for distinctively displaying selected floor with sufficient details in a three-dimensional building model 有权
    用于在三维建筑模型中显示具有足够细节的选定地板的方法和系统

    公开(公告)号:US08233008B2

    公开(公告)日:2012-07-31

    申请号:US11656171

    申请日:2007-01-19

    Abstract: A method, system and program product for distinctively displaying selected floors with sufficient details in a three-dimensional building model includes graphical metaphors that permit a selected or highlighted floor and their respective elements to be absolutely clear and distinct from the floors immediately above and below. The graphically displayed metaphors comprise “drawers”, “wireframe”, “expansion/compression”, “projected floor”, “sliding unselected floors”, “turning the pages”, “big map-small map”, and “fisheye” graphical configurations. Such graphically displayed metaphors can be utilized to highlight a selected floor, separate it from adjacent floors, and provide a graphical effect of depicting the floor's vertical position within a building.

    Abstract translation: 用于在三维建筑模型中显着地显示具有足够细节的所选楼层的方法,系统和程序产品包括允许选择或突出显示的楼层及其各自元素与紧邻上方和下方的楼层绝对清晰和不同的图形隐喻。 图形显示的隐喻包括“抽屉”,“线框”,“扩展/压缩”,“投影楼层”,“滑动未选择的楼层”,“翻页”,“大地图小地图”和“鱼眼”图形配置 。 这种图形化的隐喻可以用于突出显示所选择的地板,将其与相邻楼层分开,并且提供描绘建筑物内的地板垂直位置的图形效果。

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