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    On-chip cell migration detection
    92.
    发明申请
    On-chip cell migration detection 有权
    片上细胞迁移检测

    公开(公告)号：US20090251155A1

    公开(公告)日：2009-10-08

    申请号：US12288971

    申请日：2008-10-24

    申请人： Lei Wang ,  Jing Zhu ,  Cheng Deng ,  Jing Cheng

    发明人： Lei Wang ,  Jing Zhu ,  Cheng Deng ,  Jing Cheng

    IPC分类号： G01R27/00

    CPC分类号： G01N33/5029 ,  B01L3/502761 ,  B01L2200/10 ,  B01L2200/12 ,  B01L2300/0636 ,  B01L2300/0645 ,  B01L2300/069 ,  B01L2300/0816 ,  B01L2300/16 ,  G01N33/5438

    摘要： Techniques, systems and apparatus are disclosed for detecting impedance. In one aspect, a microelectrode sensing device includes a substrate and an array of microelectrode sensors formed on the substrate. Each sensor includes at least one conductive layer formed above the substrate and patterned to include a counter electrode and multiple sensing electrodes to detect an electrical signal in absence and presence of one or more target cells positioned on at least a portion of a surface of each sensing electrode. The sensing electrodes are spaced apart and arranged around the counter electrode to provide a spatially averaged value of the detected electrical signal.

    摘要翻译： 公开了用于检测阻抗的技术，系统和装置。 一方面，微电极感测装置包括基板和形成在基板上的微电极传感器阵列。 每个传感器包括形成在衬底上的至少一个导电层，并被图案化以包括对电极和多个感测电极，以在不存在和存在位于每个感测的表面的至少一部分上的一个或多个靶单元的情况下检测电信号 电极。 感测电极间隔开并布置在对电极周围，以提供检测到的电信号的空间平均值。

    GEOBACILLUS THERMODENITRIFICANS AS WELL AS THE SCREENING METHOD AND THE USES THEREOF
    93.
    发明申请
    GEOBACILLUS THERMODENITRIFICANS AS WELL AS THE SCREENING METHOD AND THE USES THEREOF 审中-公开
    GEOBACILLUS THERMODENITRIFICANS作为筛选方法及其用途

    公开(公告)号：US20090148881A1

    公开(公告)日：2009-06-11

    申请号：US11719556

    申请日：2005-03-22

    申请人： Lei Wang ,  Rulin Liu ,  Lu Feng ,  Fenglai Liang

    发明人： Lei Wang ,  Rulin Liu ,  Lu Feng ,  Fenglai Liang

    IPC分类号： C12Q1/68 ,  C12N1/20

    CPC分类号： C12N1/20 ,  C10G32/00 ,  C11D3/381 ,  C12N1/26 ,  C12Q1/04 ,  C12R1/01 ,  G01N2333/32

    摘要： The invention provides a strain of Geobacillus thermodenitrificans as well as the screening method and the uses thereof. The strain was deposited as the number CGMCC-1228 in the China General Microbiological Culture Collection Center of the China Committee of Culture Collection for Microorganisms. The strain was obtained by primary screening, re-screening, inoculation, domestication and propagation using the bacteria in the aqueous samples from the strata of oil field as the original screening strain. The strain screened in the invention belongs to the genus Geobacillus, which can tolerate a high temperature, and has good thermostability, which can be applied to the industrial production which need the condition of thermostable enzymes, such as fermentation, etc. With its ability of growing well in the oil-reservoir environment, degrading alkanes, decreasing viscosity and increasing fluidity of crude oil, the strain is able to remarkably enhance the yield of oil and improve the transporting efficiency of oil. Additionally, with its good ability of degrading oil, it can be developed for the treatment and clearing of the material such as the oil contaminated water, etc., so it can be useful in protection of the environment. This strain also has the ability of decreasing the surface tension of substances, which can be applied to the industry of biosurfactants preparation.

    摘要翻译： 本发明提供了一种热过氧硝酸芽孢杆菌菌株以及筛选方法及其应用。 该菌株以中国微生物培养物保藏中心微生物培养收集中心CGMCC-1228号存放。 作为原始筛选菌株，通过初步筛选，重新筛选，接种，驯化和繁殖获得的菌株是使用来自油田地层的水样品中的细菌进行的。 本发明筛选的菌株属于地热芽孢杆菌属，可耐受高温，具有良好的热稳定性，可应用于需要发酵等耐热性酶的工业生产。具有其发酵能力 在油藏环境中生长良好，降解烷烃，降低粘度，提高原油流动性，能够显着提高油的产率，提高油的输送效率。 另外，由于具有良好的降解油的能力，因此可以开发用于处理和清除油污染水等物质，因此可用于保护环境。 该菌株还具有降低物质表面张力的能力，可应用于工业生物表面活性剂的制备。

    Glycoprotein synthesis
    95.
    发明申请
    Glycoprotein synthesis 失效
    糖蛋白合成

    公开(公告)号：US20080213828A1

    公开(公告)日：2008-09-04

    申请号：US11978232

    申请日：2007-10-26

    申请人： Peter G. Schultz ,  Lei Wang ,  Zhiwen Zhang

    发明人： Peter G. Schultz ,  Lei Wang ,  Zhiwen Zhang

    IPC分类号： C07K14/435 ,  C12P21/00

    CPC分类号： C12P21/005

    摘要： Methods for making glycoproteins, both in vitro and in vivo, are provided. One method involves incorporating an unnatural amino acid into a protein and attaching one or more saccharide moieties to the unnatural amino acid. Another method involves incorporating an unnatural amino acid that includes a saccharide moiety into a protein. Proteins made by both methods can be further modified with additional sugars.

    摘要翻译： 提供在体外和体内制备糖蛋白的方法。 一种方法包括将非天然氨基酸掺入蛋白质并将一个或多个糖部分连接到非天然氨基酸上。 另一种方法包括将包含糖部分的非天然氨基酸掺入蛋白质中。 通过两种方法制备的蛋白质可以用额外的糖进一步修饰。

    Wireless Transceiver with Reduced Transmit Emissions
    96.
    发明申请
    Wireless Transceiver with Reduced Transmit Emissions 失效
    具有减少发射辐射的无线收发器

    公开(公告)号：US20080176523A1

    公开(公告)日：2008-07-24

    申请号：US11625254

    申请日：2007-01-19

    申请人： Todd Sutton ,  Srikanth Gummadi ,  Walid Hosseini ,  Lei Wang

    发明人： Todd Sutton ,  Srikanth Gummadi ,  Walid Hosseini ,  Lei Wang

    IPC分类号： H04B1/40

    CPC分类号： H04B1/0475 ,  H04B1/525 ,  H04L5/0007 ,  H04L5/003 ,  H04L5/0066

    摘要： Methods and apparatus for reducing transmit emissions are described herein. The transmit out of band emissions in an adjacent band can be reduced while complying with existing wireless communication standards through utilization of one or more of reduced transmit bandwidth, transmit operating band offset, and channel index remapping. The transceiver can support a receive operating band that is substantially adjacent to a band edge. The transmit operating band can be offset from an adjacent frequency band, and can use a narrower operating band than is supported by the receiver. The transmit baseband signal can have a reduced bandwidth to reduce the amount of noise. The frequency offset can introduce a larger transition band between the transmit operating band edges and the adjacent frequency band of interest. The transceiver can remap channel assignments to compensate for the frequency offset such that the frequency offset introduced in the transmitter is transparent to channel allocation.

    摘要翻译： 本文描述了用于减少发射发射的方法和装置。 通过利用减少的发送带宽，发射工作频带偏移和信道索引重映射中的一个或多个，可以减少相邻频带中的发射带外发射，同时遵守现有的无线通信标准。 收发器可以支持基本上与带边缘相邻的接收工作频带。 发射工作频带可以偏离相邻频带，并且可以使用比由接收机支持的更窄的工作频带。 发射基带信号可以具有减小的带宽以减少噪声量。 频率偏移可以在发射工作频带边缘和感兴趣的相邻频带之间引入更大的转换频带。 收发器可以重新分配信道分配以补偿频率偏移，使得在发射机中引入的频率偏移对信道分配是透明的。

    Site specific incorporation of heavy atom-containing unnatural amino acids into proteins for structure determination
    97.
    发明授权
    Site specific incorporation of heavy atom-containing unnatural amino acids into proteins for structure determination 失效
    将重原子含有非天然氨基酸的位点特异性并入蛋白质进行结构测定

    公开(公告)号：US07399619B2

    公开(公告)日：2008-07-15

    申请号：US11137850

    申请日：2005-05-24

    申请人： Jianming Xie ,  Lei Wang ,  Ning Wu ,  Peter G. Schultz

    发明人： Jianming Xie ,  Lei Wang ,  Ning Wu ,  Peter G. Schultz

    IPC分类号： C12P21/06 ,  C07H21/04 ,  C12N9/00 ,  C12N1/21 ,  G06F19/00 ,  G01N33/48 ,  G01N33/50

    CPC分类号： C12N9/93 ,  C07H21/04 ,  C12N15/67 ,  C12P21/02

    摘要： Translation systems and other compositions including orthogonal aminoacyl tRNA-synthetases that preferentially charge an orthogonal tRNA with an iodinated or brominated amino acid are provided. Nucleic acids encoding such synthetases are also described, as are methods and kits for producing proteins including heavy atom-containing amino acids, e.g., brominated or iodinated amino acids. Methods of determining the structure of a protein, e.g., a protein into which a heavy atom has been site-specifically incorporated through use of an orthogonal tRNA/aminoacyl tRNA-synthetase pair, are also described.

    摘要翻译： 提供了翻译系统和包括正交氨酰基tRNA合成酶的其它组合物，其优先用碘化或溴化氨基酸对正交的tRNA进行充电。 还描述了编码这种合成酶的核酸，以及用于产生蛋白质的方法和试剂盒，包括含重原子的氨基酸，例如溴化或碘化​​氨基酸。 还描述了确定蛋白质结构的方法，例如通过使用正交的tRNA /氨基酰基tRNA-合成酶对将重原子特异性并入的蛋白质的蛋白质。

    Managing Power Consumption in a NIC Team
    98.
    发明申请
    Managing Power Consumption in a NIC Team 有权
    管理NIC团队中的功耗

    公开(公告)号：US20080101230A1

    公开(公告)日：2008-05-01

    申请号：US11554015

    申请日：2006-10-28

    申请人： Wei Liu ,  Lei Wang ,  Jianwen Yin

    发明人： Wei Liu ,  Lei Wang ,  Jianwen Yin

    IPC分类号： H04J1/16

    CPC分类号： H04L47/10 ,  H04L12/12 ,  H04L47/125 ,  Y02D50/20 ,  Y02D50/40 ,  Y02D50/42

    摘要： The present disclosure provides an information handling system which includes a team of network interface controllers (NIC), each controller operable to receive network traffic load. The system also includes logic configured to direct the network traffic load to at least one NIC in the team based on the network traffic load. The present disclosure may result in overall power savings for system.

    摘要翻译： 本公开提供了一种信息处理系统，其包括一组网络接口控制器（NIC），每个控制器可操作以接收网络业务负载。 该系统还包括配置为基于网络流量负载将网络流量负载引导到团队中的至少一个NIC的逻辑。 本公开可以导致系统的总体功率节省。

    ERROR-TOLERANT MULTI-THREADED MEMORY SYSTEMS WITH REDUCED ERROR ACCUMULATION
    99.
    发明申请
    ERROR-TOLERANT MULTI-THREADED MEMORY SYSTEMS WITH REDUCED ERROR ACCUMULATION 有权
    具有减少错误累积的容错多通道存储器系统

    公开(公告)号：US20080082893A1

    公开(公告)日：2008-04-03

    申请号：US11863353

    申请日：2007-09-28

    申请人： Lei Wang

    发明人： Lei Wang

    IPC分类号： G06F11/10 ,  G06F11/14 ,  G06F9/46

    CPC分类号： G06F11/1008 ,  G06F11/00 ,  G06F11/1076 ,  G06F11/1658 ,  G06F11/1666 ,  G06F11/20

    摘要： Systems and methods establishing and/or utilizing an error-tolerant multithreaded register file are provided. The systems and methods employ dynamic multithreading redundancy (DMR) for error correction. Non-overlapped register access patterns associated create hardware redundancy dynamically that is exploited for error control. Immediate write-back and self-recovery techniques are employed to further enhance the error correction functionalities of the disclosed systems and methods. Error control is improved for memory components and processing functions in multithreaded computing systems.

    摘要翻译： 提供了建立和/或利用容错多线程寄存器文件的系统和方法。 系统和方法采用动态多线程冗余（DMR）进行纠错。 非重叠寄存器访问模式相关联创建动态的硬件冗余，用于错误控制。 采用立即回写和自恢复技术来进一步增强公开的系统和方法的纠错功能。 改进了多线程计算系统中的内存组件和处理功能的错误控制。

    Maize bZIP transcription factors and genes encoding the same and use thereof
    100.
    发明申请
    Maize bZIP transcription factors and genes encoding the same and use thereof 审中-公开

    公开(公告)号：US20080060098A1

    公开(公告)日：2008-03-06

    申请号：US11810795

    申请日：2007-06-07

    申请人： Jun Zhao ,  Lei Wang ,  Yunliu Fan

    发明人： Jun Zhao ,  Lei Wang ,  Yunliu Fan

    IPC分类号： A01H5/00 ,  C12N1/20 ,  C12N15/00 ,  C12N15/11 ,  C12N5/06

    CPC分类号： C07K14/415 ,  C12N15/8271

    摘要： The invention discloses maize bZIP transcriptional factors, namely, ABP2, ABP4 and ABP9, the genes encoding these factors, and the use thereof. The transcriptional factors are proteins having an amino acid sequence set forth in SEQ ID NO: 2, 4, or 6, or proteins derived therefrom by substitution, deletion or addition of one or more amino acid residues of SEQ ID NO: 2, 4, or 6, and having the same activity as a protein shown by SEQ ID NO: 2, 4, or 6. The ABP2, ABP4 and ABP9 genes encoding these factors, respectively, are the DNA sequences having an identity of more than 90% with a sequence shown by SEQ ID NO: 1, 3 or 5 and the encoded proteins having such same functions. These genes are important for breeding plant varieties with an enhanced tolerance to abiotic stresses and for improving plant tolerance to abiotic stresses.