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    Petri dish including locking means for forming a stack
    91.
    发明授权
    Petri dish including locking means for forming a stack 有权
    培养皿包括用于形成堆的锁定装置

    公开(公告)号：US09127247B2

    公开(公告)日：2015-09-08

    申请号：US13806091

    申请日：2011-05-24

    申请人： Stéphane Huet ,  Jérôme Thepaut ,  Christophe Gincheleau ,  Frédéric Simon ,  Frank Reverdy

    发明人： Stéphane Huet ,  Jérôme Thepaut ,  Christophe Gincheleau ,  Frédéric Simon ,  Frank Reverdy

    IPC分类号： C12M1/22 ,  C12M3/00 ,  B01L3/00

    CPC分类号： C12M23/46 ,  B01L3/508 ,  B01L3/50853 ,  B01L2200/025 ,  B01L2300/041 ,  C12M23/10 ,  C12M23/44

    摘要： A Petri dish has members including a receptacle and an additional lid, both having an axisymmetric shape and which are delimited by a bottom wall and at least one peripheral wall, the receptacle and lid bearing complementary lock sections so that when a stack is formed by superposing at least two dishes, borne by a first component of a first dish which can engage with the lock section of the second component of the second dish, thus making them rigidly connected to one another. These lock sections cooperate by relative rotational movement of one dish with respect to the other, the lock sections being borne by the peripheral walls and including protrusions.

    摘要翻译： 培养皿具有包括容器和附加盖的构件，两者具有轴对称形状，并且由底壁和至少一个周壁限定，所述容器和盖承载互补的锁定部分，使得当通过叠加形成堆叠时 至少两个盘，由第一盘的第一部件承载，其可以与第二盘的第二部件的锁定部分接合，从而使它们彼此刚性连接。 这些锁定部分通过一个盘相对于另一个的相对旋转运动协作，锁定部分由周壁承载并且包括突起。

    Method of staging a tissue sample cassette
    92.
    发明授权
    Method of staging a tissue sample cassette 有权
    分组组织样品盒的方法

    公开(公告)号：US09097630B2

    公开(公告)日：2015-08-04

    申请号：US14105355

    申请日：2013-12-13

    申请人： BioPath Automation, L.L.C.

    发明人： Warren P. Williamson, IV ,  Craig B. Berky ,  Stephen P. Whitlatch ,  Thomas J. Ward

    IPC分类号： G01N1/28 ,  G01N1/36 ,  B01L3/00 ,  B01L9/00 ,  G01N1/31

    CPC分类号： G01N1/36 ,  B01L3/508 ,  B01L9/52 ,  B01L2300/043 ,  G01N2001/315 ,  G01N2001/366 ,  Y10T436/25

    摘要： A method of staging a tissue sample cassette, including a cassette body and a lid, from an upper position in a frame used during a tissue embedding process to a lower position in the frame. The method comprises coupling the cassette with the frame such that the cassette is in the upper position and positively stopped at the upper position by first structure on a wall of the frame. The cassette is moved relative to the frame to the lower position by selectively engaging the cassette with a staging mechanism. An external force is applied to the cassette with the staging mechanism in a direction to move the cassette from the upper position toward the lower position. The cassette is retained in the lower position using second structure on the wall of the frame, such that the cassette is exposed for embedding the cassette in an embedding medium and subsequently slicing the tissue sample embedded in the embedding medium.

    摘要翻译： 一种从在组织嵌入过程中使用的框架中的上部位置将组织样本盒（包括盒体和盖子）分层到框架中的下部位置的方法。 该方法包括将盒子与框架连接，使得盒子处于上部位置，并且通过框架壁上的第一结构在上部位置上被主动地停止。 通过选择性地将盒与分段机构接合，盒带相对于框架移动到下部位置。 一个外力作用在盒子上，其中分段机构沿一个使盒子从上部位置向下位置运动的方向。 使用框架壁上的第二结构将盒子保持在下部位置，使得盒子被暴露以将盒子嵌入到嵌入介质中，并随后切片嵌入在嵌入介质中的组织样本。

    INLET CLOSURE MECHANISM
    94.
    发明申请
    INLET CLOSURE MECHANISM 审中-公开
    入口关闭机构

    公开(公告)号：US20150192209A1

    公开(公告)日：2015-07-09

    申请号：US14419764

    申请日：2013-08-08

    申请人： Smiths Detection-Watford Limited

    发明人： John Patrick Fitzgerald

    IPC分类号： F16K3/316 ,  F16K27/04 ,  F16K3/22

    CPC分类号： F16K3/3165 ,  B01L3/508 ,  B01L3/50825 ,  B01L2300/045 ,  F16K3/22 ,  F16K27/04 ,  G01N27/622

    摘要： An inlet closure assembly includes a housing that defines an inlet configured to receive a fluid, such as airflow from the surrounding environment. The inlet closure assembly also includes a seal member that defines an inlet path in fluid communication with the inlet defined by the housing. The inlet closure assembly further includes a seat member configured to seat with respect to the seal member. The seat member is configured to obstruct the inlet path in its seated orientation. The inlet closure assembly also includes an actuation member configured to move the seat member into and out of seated engagement with the seal member. The inlet closure assembly further includes a biasing member for biasing the seat member into seated engagement with the seal member when the seat member is positioned to obstruct the inlet. The biasing member can be implemented using a magnet, a spring, and so forth.

    摘要翻译： 入口闭合组件包括壳体，其限定被配置为接收流体的入口，例如来自周围环境的气流。 入口闭合组件还包括密封构件，其限定与由壳体限定的入口流体连通的入口路径。 入口封闭组件还包括配置成相对于密封构件安置的座构件。 座椅构件构造成阻碍入口路径处于其安置方向。 入口闭合组件还包括构造成将座椅构件移动到与密封构件的就位接合中的致动构件。 入口封闭组件还包括偏置构件，用于当座椅构件被定位成阻碍入口时，偏压座椅构件与密封构件就座接合。 偏置构件可以使用磁体，弹簧等来实现。

    QPCR Analysis Apparatus
    95.
    发明申请
    QPCR Analysis Apparatus 审中-公开
    QPCR分析仪

    公开(公告)号：US20150165440A1

    公开(公告)日：2015-06-18

    申请号：US14539822

    申请日：2014-11-12

    申请人： STOKES BIO LIMITED

    发明人： Mark Davies ,  John Daly ,  Tara Dalton

    IPC分类号： B01L7/00 ,  G01N21/64

    CPC分类号： B01L7/525 ,  B01L3/508 ,  B01L7/54 ,  B01L2300/0654 ,  B01L2300/0809 ,  B01L2300/1827 ,  B01L2400/0442 ,  B01L2400/0445 ,  G01N21/6428 ,  G01N2021/6439 ,  G01N2201/062

    摘要： An apparatus (1) is for DNA amplification with quantitative measurements. A biological sample is held in a cell (2) for the amplification, the cell (2) defining a single space within which the sample rotates. On one side a copper heater (3) is located to supply heat to the cell (2), and on the other side there is a cooling copper block (4) withdrawing heat from the cell. The locations of the heater (3) and the cooling block (4) generate a natural convection loop internally within the cell (2) without need for active cooling—the block (4) passively cooling by withdrawing heat from the direction of the heater (3). A detector (9, 27) captures readings in real time and a processor (10) generates an S-curve for change of sample emission with time. The S-curve (FIGS. 4 and 5) also includes a thermal cycle number corresponding to the time parameter, so that the S-curve is given in the traditional qPCR intensity vs. cycle number.

    摘要翻译： 装置（1）用于通过定量测量进行DNA扩增。 将生物样品保持在用于扩增的细胞（2）中，细胞（2）限定样品旋转的单个空间。 在一侧，铜加热器（3）被定位成向电池（2）供热，另一侧有一个冷却铜块（4）从电池中取出热量。 加热器（3）和冷却块（4）的位置在电池（2）内部产生自然对流回路，而不需要主动冷却 - 通过从加热器的方向抽出热量来阻止块（4）的被动冷却（ 3）。 检测器（9,27）实时捕获读数，并且处理器（10）产生用于随时间改变样品发射的S曲线。 S曲线（图4和图5）还包括对应于时间参数的热循环数，使得S曲线以传统的qPCR强度对周期数给出。

    MEASURING CASSETTE AND MEASURING DEVICE FOR THE DETECTION OF TARGET MOLECULES IN A LIQUID SAMPLE BY MEASUREMENT OF FLUORESCENCE EMISSION AFTER EXCITATION IN AN EVANESCENT FIELD
    96.
    发明申请
    MEASURING CASSETTE AND MEASURING DEVICE FOR THE DETECTION OF TARGET MOLECULES IN A LIQUID SAMPLE BY MEASUREMENT OF FLUORESCENCE EMISSION AFTER EXCITATION IN AN EVANESCENT FIELD 有权
    测量CASSETTE和测量装置，用于通过在EVANESCENT FIELD中激活后测量荧光发射来检测液体样品中的目标分子

    公开(公告)号：US20150079694A2

    公开(公告)日：2015-03-19

    申请号：US13811959

    申请日：2011-07-19

    申请人： Roland SCHENK

    发明人： Roland SCHENK

    IPC分类号： B01L3/00

    CPC分类号： B01L3/508 ,  B01F5/0647 ,  B01F13/0059 ,  B01F13/1016 ,  B01L3/502707 ,  B01L3/502715 ,  B01L3/502761 ,  B01L2200/027 ,  B01L2200/04 ,  B01L2200/0647 ,  B01L2300/0654 ,  B01L2300/0877 ,  B01L2300/0887 ,  B01L2400/0487 ,  G01N21/05 ,  G01N21/648 ,  G01N2021/0346 ,  G01N2021/056

    摘要： An interchangeable disposable measuring cassette for insertion into a measuring apparatus for detecting target molecules in a liquid sample by measuring fluorescence emission has a flow measurement cell in which an excitation radiation provided by the measuring apparatus produces an evanescent field in the liquid sample beyond a boundary layer for the liquid sample and the measurement cell. To be better able to ensure that no sample liquid can cross from the measurement cell into the measuring apparatus, the measuring cassette includes a body including an optically transparent material and a base in contact with the underside of the body. The measurement cell is formed by a cutout provided in the body, the base, or both. The areas on which the body and the base are on top of one another around this cutout are connected to one another directly and in fluid-tight fashion by laser welding.

    摘要翻译： 用于插入到用于通过测量荧光发射来检测液体样品中的目标分子的测量装置的可互换的一次性测量盒具有流量测量单元，其中由测量装置提供的激发辐射在液体样品中产生超出边界层的渐逝场 用于液体样品和测量池。 为了更好地确保没有样品液体可以从测量单元穿过测量装置，测量盒包括主体，其包括光学透明材料和与主体下侧接触的基部。 测量单元由设置在主体，基座或两者中的切口形成。 主体和基座在该切口周围彼此顶部的区域通过激光焊接直接并以流体密封的方式彼此连接。

    CONTAINER FOR THE LABORATORY AREA AND METHOD FOR MARKING SUCH A CONTAINER
    100.
    发明申请
    CONTAINER FOR THE LABORATORY AREA AND METHOD FOR MARKING SUCH A CONTAINER 审中-公开
    用于实验室的容器和用于标记容器的方法

    公开(公告)号：US20140328735A1

    公开(公告)日：2014-11-06

    申请号：US13973571

    申请日：2013-08-22

    申请人： Weidmann Plastics Technology AG

    发明人： John TINNER ,  Walter Albert ,  Karl Mazenauer

    IPC分类号： B01L3/00 ,  B23K26/00

    CPC分类号： B01L3/508 ,  B01L3/545 ,  B01L3/5453 ,  B01L2300/021 ,  B23K26/352

    摘要： Container (10, 10′) for the laboratory area, having: a body (1) with a layer (2) that is opaque to an optical reader, is applied to the body and has clearances (21) in the form of machine-readable data, the body (1) having at least one local material modification (3), and the material modification (3) together with the opaque layer (2) forming a reading area (6), in which the machine-readable data can be read from the outside by an optical reader on the basis of the optical contrast between the material modification (3) and the opaque layer (2).

    摘要翻译： 具有：具有：具有对于光学读取器不透明的层（2）的主体（1）的实验室区域的容器（10,10'）施加到主体并具有机器形式的间隙（21） 所述主体（1）具有至少一个局部材料修改（3）和所述材料修改（3）以及形成读取区域（6）的所述不透明层（2），其中所述机器可读数据可以 基于材料修改（3）和不透明层（2）之间的光学对比度，通过光学读取器从外部读取。