公开(公告)号：US20190106639A1

公开(公告)日：2019-04-11

申请号：US16183649

申请日：2018-11-07

申请人： The University of Wyoming Research Corporation d/b/a Western Research Institute

发明人： Joseph F. Rovani, JR. ,  Jeramie Joseph Adams ,  Ryan Bradley Boysen ,  Jean-Pascal Planche ,  Nicholas David Bolton

IPC分类号： C10G25/00 ,  B01D15/26 ,  G01N30/46 ,  C10G53/08 ,  G01N33/28 ,  B01J20/281 ,  B01J20/283 ,  B01J20/284 ,  G01N30/14 ,  B01D15/00 ,  C10G25/12 ,  B01J20/287 ,  B01J20/286

CPC分类号： C10G25/003 ,  B01D15/00 ,  B01D15/265 ,  B01J20/281 ,  B01J20/283 ,  B01J20/284 ,  B01J20/286 ,  B01J20/287 ,  C10G25/12 ,  C10G53/08 ,  C10G2400/30 ,  G01N30/14 ,  G01N30/461 ,  G01N30/468 ,  G01N33/2823 ,  G01N33/2835 ,  G01N2030/027 ,  G01N2030/085 ,  G01N2030/143 ,  G01N2030/8854

摘要： The present invention is generally related to the analysis of chemical compositions of hydrocarbons and hydrocarbon blends. This method applies specifically to the problem of analyzing extremely complex hydrocarbon-containing mixtures when the number and diversity of molecules makes it impossible to realistically identify and quantify them individually in a reasonable timeframe and cost. The advantage to this method over prior art is the ability to separate and identify chemical constituents and solvent fractions based on their solvent-solubility characteristics, their high performance liquid chromatographic (HPLC) adsorption and desorption behaviors, and their interactions with stationary phases; and subsequently identify and quantify them at least partially using various combinations of non-destructive HPLC, destructive HPLC, and stand-alone detectors presently not routinely used for HPLC but reconfigured to obtain spectra on the fly. This analytical method is especially useful for, but not limited to, asphalt binders and asphalt binder blends, modified asphalts, asphalt modifiers, asphalt additives, polymer-modified asphalts, asphalts containing rejuvenators and softening agents, asphalts containing recycled products, aged asphalts, and air-blown asphalts, which may contain wide varieties of different types of additives and chemistries, and forensic applications, and environmental pollutant identification.

公开(公告)号：US10247642B2

公开(公告)日：2019-04-02

申请号：US15619456

申请日：2017-06-10

申请人： NANJING UNIVERSITY

发明人： Qing Zhou ,  Wei Wang ,  Aimin Li ,  Qingqing Zhao ,  Minglu Wang ,  Rui Gao ,  Xiaowen Ma ,  Peng Shi ,  Xun Chen

IPC分类号： G01N1/18 ,  G01N30/14 ,  G01N1/40 ,  B03C1/033 ,  B03C1/28 ,  G01N1/10

摘要： A device comprises a contact reaction chamber, a circulating water inlet, a clear water basin, a circulating pump, a circulating water outlet, a solid phase extractant collecting tank, a magnetic holder, an electromagnet, a solid-liquid separation area, a drain valve, a wall sprinkling water inlet, and a wall sprinkling pipe, wherein, the contact reaction chamber is in a conical shape, and utilizes hydraulic power to perform stir to ensure no dead corner exists during contact stir; the obconical solid-liquid separation area increases the action area between a magnetic solid phase extractant and the electromagnet; the solid phase extractant collecting tank is in a downwards protruding dish shape to prevent the solid phase extractant from losing.

公开(公告)号：US10012623B2

公开(公告)日：2018-07-03

申请号：US15529309

申请日：2015-11-20

申请人： Marco Cisterni

发明人： Marco Cisterni

IPC分类号： H01J49/00 ,  G01N30/72 ,  G01N30/14 ,  H01J49/14

CPC分类号： G01N30/7206 ,  G01N30/14 ,  G01N2030/143 ,  H01J49/0031 ,  H01J49/10 ,  H01J49/145 ,  H01J49/147

摘要： Gas chromatograph-mass spectrometer comprising an ion source, the walls of which are realized or covered with at least one layer of graphene. Thus realized, the gas chromato graph-mass spectrometer proves to be particularly suited to the analysis samples containing hydrogen in addition to the substances to be analyzed. This situation generally occurs when the mass spectrometer is coupled to a gas chromatograph that utilizes hydrogen as the carrier gas.

公开(公告)号：US09770678B2

公开(公告)日：2017-09-26

申请号：US14687290

申请日：2015-04-15

申请人： Waters Technologies Corporation

发明人： Michael R. Jackson ,  Christopher Seith ,  Steven J. Ciavarini ,  Kara O'Donnell ,  John Angelosanto ,  John Leason

IPC分类号： B01D19/00 ,  B01D15/08 ,  B01D15/16 ,  G01N30/26 ,  G01N30/14 ,  G01N30/34

CPC分类号： B01D19/0073 ,  B01D15/08 ,  B01D15/16 ,  B01D19/0036 ,  B01D19/0063 ,  B01D19/0068 ,  G01N30/14 ,  G01N30/26 ,  G01N30/34

摘要： Described is a method for vacuum degassing of a liquid such as a solvent for a liquid chromatography system. The method includes modulating application of a vacuum to a fluid channel of a degasser so that each volume of a liquid drawn from the degasser experiences a residence time that is equal to the residence times of the other volumes. The residence time is determined as a time that the volume resides in the fluid channel under application of the vacuum and to a magnitude of the applied vacuum. The method is advantageous for use with liquid chromatography systems where differences in the diffusion rates of solvents into the degasser vacuum can otherwise introduce error into the composition gradient of a mobile phase.

公开(公告)号：US09594007B2

公开(公告)日：2017-03-14

申请号：US14309051

申请日：2014-06-19

申请人： EMD Millipore Corporation

发明人： Chris Scott ,  Rob Colonna ,  Christopher Barmore ,  Todd Taylor ,  Daniel Morgan

IPC分类号： G01N1/28 ,  G01N1/40 ,  G01N30/14 ,  B01J20/281 ,  B01D61/18 ,  B01L3/00

CPC分类号： G01N1/28 ,  B01D61/18 ,  B01J20/281 ,  B01L3/50255 ,  G01N1/4077 ,  G01N30/14 ,  G01N2030/146

摘要： Sample preparation device for receiving in sealing relation one or more filter assemblies and one or more sample containers, each container uniquely positioned within the device to receive filtered sample from a designated filter. The device includes a body, a lid disposed on the body, a container tray, a base, an integrated seal on the body, a valve and a valve actuator. The tray can be disposed in a vacuum chamber defined by the lid and the body, and one or more sample containers can be disposed in the tray. When properly positioned in the tray in the vacuum chamber, each container is in fluid communication with a single respective filter assembly disposed in sealing relation in a respective aperture in the lid. A single actuation of a valve to place the vacuum chamber under vacuum causes the lid to seal to the base and drives the simultaneous filtration of a plurality of samples.

摘要翻译： 用于以密封关系接收一个或多个过滤器组件和一个或多个样品容器的样品制备装置，每个容器唯一地定位在装置内以从指定的过滤器接收经过滤的样品。 该装置包括主体，设置在主体上的盖，容器托盘，基座，主体上的集成密封件，阀和阀致动器。 托盘可以设置在由盖和主体限定的真空室中，并且一个或多个样品容器可以设置在托盘中。 当适当地定位在真空室中的托盘中时，每个容器与在盖中的相应孔中以密封关系设置的单个相应的过滤器组件流体连通。 将真空室置于真空下的阀的单次致动导致盖子密封到基座并驱动多个样品的同时过滤。

公开(公告)号：US09568460B2

公开(公告)日：2017-02-14

申请号：US14471956

申请日：2014-08-28

申请人： King Fahd University of Petroleum and Minerals ,  King Abdulaziz City for Science and Technology

发明人： Basheer Chanbasha ,  Ibrahim Mohammed Al-Zahrani ,  Than Htun

IPC分类号： G01N30/62 ,  G01N33/28 ,  G01N30/02 ,  G01N33/00 ,  G01N30/14 ,  G01N30/88 ,  G01N21/76 ,  G01N30/74 ,  G01N1/40 ,  G01N30/00

CPC分类号： G01N33/287 ,  G01N1/4055 ,  G01N21/766 ,  G01N30/02 ,  G01N30/14 ,  G01N30/74 ,  G01N30/88 ,  G01N33/0044 ,  G01N2001/4061 ,  G01N2030/009 ,  G01N2030/146 ,  G01N2030/8854

摘要： A liquid phase microextraction (LPME) method was developed for the determination of sulfur compounds in crude oils and its fractions (e.g diesel). Wide ranges of sulfur compounds including benzothiophene, dibenzothiophene and their derivatives were used as model compounds for extraction. After extraction, the analyses were performed by gas chromatography equipped with sulfur chemiluminescence detector (GC-SCD). Various experiments conditions influencing the extraction such as extraction times, extraction solvents, solvent volume and quantitative parameters were optimized to achieve higher extraction efficiency and high accuracy. The optimized conditions were applied to the determination of sulfur compounds in crude oil and diesel.

摘要翻译： 开发了液相微萃取（LPME）方法，用于测定原油及其馏分（如柴油）中的硫化合物。 使用范围广泛的硫化合物，包括苯并噻吩，二苯并噻吩及其衍生物作为萃取模型化合物。 提取后，通过装有硫化学发光检测器（GC-SCD）的气相色谱进行分析。 优化萃取时间，提取溶剂，溶剂体积和定量参数等各种实验条件，提高萃取效率，提高准确度。 优化条件适用于原油和柴油中硫化合物的测定。

公开(公告)号：US09540454B2

公开(公告)日：2017-01-10

申请号：US14565671

申请日：2014-12-10

申请人： University of Miyazaki ,  Fuso Pharmaceutical Industries, Ltd.

发明人： Michio Muguruma ,  Hiroshi Murata

IPC分类号： A61K31/726 ,  A61K31/70 ,  C08B37/00 ,  A61K31/727 ,  G01N30/14

CPC分类号： C08B37/0075 ,  A61K31/727 ,  C08B37/0003 ,  C08B37/0078 ,  G01N30/14 ,  Y10T436/14 ,  Y10T436/142222 ,  Y10T436/143333

摘要： The present invention provides a high purity heparin useful to be a pharmaceutical product, cosmetics, research reagent, or the like, and a method for producing the same, more specifically, a heparin which does not substantially contain a nitrous acid degradation-resistant impurity and a method for producing a heparin, comprising mixing an aqueous solution of 5 to 30% by weight of the heparin with ethanol having an amount (volume) 0.2 to 1 times the amount (volume) of the aqueous heparin solution to obtain a colloidal precipitate of heparin.

摘要翻译： 本发明提供了可用作药物，化妆品，研究试剂等的高纯度肝素及其制造方法，更具体而言，是基本上不含有亚硝酸降解性杂质的肝素， 一种肝素的制造方法，其特征在于，将5〜30重量％的肝素水溶液与乙醇配合（体积）为肝素水溶液的量（体积）的0.2〜1倍，得到胶体沉淀物 肝素。

公开(公告)号：US20160153945A1

公开(公告)日：2016-06-02

申请号：US14905489

申请日：2014-07-18

申请人： TOTAL S.A.

发明人： Daniel DESSORT ,  Jacques BICKERT

IPC分类号： G01N30/86 ,  G01N30/14 ,  G01N30/72

CPC分类号： G01N30/86 ,  G01N30/14 ,  G01N30/72 ,  G01N30/7206 ,  G01N30/8675 ,  G01N2030/025 ,  G01N2030/884

摘要： The present disclosure relates to a method for constituting a collection of chromatograms of a reference mixture of organic compounds. The present disclosure also relates to a method for the identification of compounds in a sample of an organic mixture using a collection of chromatograms. A kit is also provided for the identification of at least one compound in a sample from an organic mixture. The method and kit belong to the field of analytical chemistry.

摘要翻译： 本公开涉及构成有机化合物的参考混合物的色谱图的集合的方法。 本公开还涉及使用色谱图的集合来鉴定有机混合物样品中化合物的方法。 还提供了用于鉴定来自有机混合物的样品中至少一种化合物的试剂盒。 该方法和试剂盒属于分析化学领域。

公开(公告)号：US09274091B2

公开(公告)日：2016-03-01

申请号：US13853551

申请日：2013-03-29

申请人： Brooks Rand Inc

发明人： Paul Danilchik

IPC分类号： G01N30/14 ,  G01N1/28 ,  G01N33/18 ,  G01N1/38 ,  G01N1/40 ,  G01N30/02 ,  G01N30/84

CPC分类号： G01N30/14 ,  G01N1/28 ,  G01N1/38 ,  G01N33/1826 ,  G01N2001/4066 ,  G01N2030/025 ,  G01N2030/8405

摘要： In accordance with one embodiment of the present disclosure, a method for processing a liquid test sample includes using a needle assembly to introduce a first flow of gas through an inlet in the needle assembly into a container containing a liquid test sample and to provide an outlet from the container through the needle assembly, separating at least one volatile component from the sample in a gas and liquid separator using the first flow of gas, adsorbing the at least one volatile component onto a trapping material to provide at least one adsorbed component, and releasing the at least one adsorbed component from the trapping material to provide at least one released component.

摘要翻译： 根据本公开的一个实施例，用于处理液体测试样品的方法包括使用针组件将第一气流通过针组件中的入口引入容纳液体测试样品的容器中并提供出口 从容器通过针组件，使用第一气体流将气体和液体分离器中的至少一种挥发性组分与样品分离，将至少一种挥发性组分吸附到捕集材料上以提供至少一种吸附组分，以及 从所述捕获材料释放所述至少一种吸附组分以提供至少一种释放的组分。

公开(公告)号：US20150377842A1

公开(公告)日：2015-12-31

申请号：US14750693

申请日：2015-06-25

申请人： PureHoney Technologies, Inc.

发明人： Can Ozbal

IPC分类号： G01N30/14 ,  G01N33/49 ,  G01N30/72

CPC分类号： G01N30/7233 ,  G01N30/08 ,  G01N30/6091 ,  G01N30/6095 ,  G01N33/491

摘要： Systems, apparatus, methods, and kits are provided for automated mass spectrometric analysis of small volumes of liquid samples, such as biological samples. The systems, apparatus, and kits may be used in facilities where high throughput of samples, as well as reliable and repeatable assay results with little training of staff, are needed. Such facilities include hospital emergency wards.

摘要翻译： 提供了系统，装置，方法和试剂盒，用于对小体积液体样品（如生物样品）进行自动质谱分析。 系统，装置和试剂盒可用于需要高通量样品以及可靠且可重复的测定结果，而且不需要人员培训的设备。 这些设施包括医院急诊室。