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    Ion Trap and a Method for Dissociating Ions in an Ion Trap
    111.
    发明申请
    Ion Trap and a Method for Dissociating Ions in an Ion Trap 有权
    离子阱和离子阱中离子离子的分离方法

    公开(公告)号：US20080035841A1

    公开(公告)日：2008-02-14

    申请号：US10598185

    申请日：2005-02-23

    Applicant: Li Ding

    Inventor： Li Ding

    IPC: B01D59/44

    CPC classification number: H01J49/42 ,  H01J49/0054

    Abstract: A quadrupole ion trap includes a switch 3 for switching a trapping voltage between discrete voltage levels VH, VL. This creates a digital trapping field for trapping precursor ions and product ions in a trapping region of the ion trap. A gating voltage is applied to a gate electrode 12 to control injection of source electrons into the ion trap. Application of the gating voltage is synchronised with the switching so that electrons are injected into the trapping region while the trapping voltage is at a selected one of the voltage levels and can reach the trapping region with a kinetic energy suitable for electron capture dissociation to take place.

    Abstract translation: 四极离子阱包括用于在离散电压V H，V L L之间切换捕获电压的开关3。 这产生了用于在离子阱的捕获区捕获前体离子和产物离子的数字捕获场。 施加门极电压到栅电极12以控制将源电子注入到离子阱中。 门控电压的施加与开关同步，使得电子注入捕获区域，同时捕获电压处于选定的一个电压电平并且可以以适合于电子捕获解离的动能达到捕获区域发生 。

    Optical Material and Method for Modifying the Refractive Index
    112.
    发明申请
    Optical Material and Method for Modifying the Refractive Index 审中-公开
    用于改变折射率的光学材料和方法

    公开(公告)号：US20080001320A1

    公开(公告)日：2008-01-03

    申请号：US11745746

    申请日：2007-05-08

    Applicant: Wayne H. Knox ,  Li Ding ,  Jay Friedrich Kunzler ,  Dharmendra M. Jani

    Inventor： Wayne H. Knox ,  Li Ding ,  Jay Friedrich Kunzler ,  Dharmendra M. Jani

    IPC: A61F2/16 ,  G02B1/12

    CPC classification number: A61F2/1624 ,  A61F2/16 ,  A61F2/1627 ,  A61F2/1635 ,  A61F9/008 ,  A61F9/00834 ,  A61F2009/00842 ,  A61F2009/00897 ,  G02C7/04 ,  G02C2202/14

    Abstract: A method for modifying the refractive index of an optical, polymeric material. The method comprises irradiating select regions of the optical, polymeric material with a focused, visible or near-IR laser having a pulse energy from 0.05 nJ to 1000 nJ. The irradiation results in the formation of refractive optical structures, which exhibit little or no scattering loss. The method can be used to modify the refractive index of an intraocular lens following the surgical implantation of the intraocular lens in a human eye. The invention is also directed to an optical device comprising refractive optical structures, which exhibit little or no scattering loss and are characterized by a positive change in refractive index.

    Abstract translation: 用于改变光学聚合物材料的折射率的方法。 该方法包括用具有0.05nJ至1000nJ的脉冲能量的聚焦，可见或近红外激光照射光学聚合物材料的选择区域。 照射导致折射光学结构的形成，其表现出很少或没有散射损失。 该方法可以用于在人眼中手术植入人工晶状体后修改眼内透镜的折射率。 本发明还涉及一种包括折射光学结构的光学装置，其表现出很少或没有散射损失，并且其特征在于折射率的正变化。

    Quadrupole ion trap device and methods of operating a quadrupole ion trap device
    113.
    发明授权
    Quadrupole ion trap device and methods of operating a quadrupole ion trap device 有权
    四极离子阱装置及操作四极离子阱装置的方法

    公开(公告)号：US07285773B2

    公开(公告)日：2007-10-23

    申请号：US10494493

    申请日：2002-10-24

    Applicant: Li Ding ,  Michael Sudakov

    Inventor： Li Ding ,  Michael Sudakov

    IPC: H01J49/42

    CPC classification number: H01J49/424 ,  H01J49/06

    Abstract: A quadrupole ion trap device has a field adjusting electrode located outside the trapping region adjacent the aperture in the entrance end cap electrode, and optionally adjacent the aperture in the exit end cap electrode. The field adjusting electrode(s) controls field distortion in the vicinity of the apertures. By appropriately setting the voltages on the field adjusting electrodes the efficiency and resolution of operational processes such as ion introduction, precursor ion isolation and mass scanning can be improved.

    Abstract translation: 四极离子阱装置具有位于与入口端盖电极中的孔附近的捕获区域外部的场调节电极，并且可选地邻近出口端盖电极中的孔。 场调节电极控制孔附近的场失真。 通过适当地设定场调节电极上的电压，可以提高离子引入，前体离子隔离和质量扫描等操作过程的效率和分辨率。

    Methods and apparatus for driving a quadrupole ion trap device
    114.
    发明授权
    Methods and apparatus for driving a quadrupole ion trap device 有权
    用于驱动四极离子阱装置的方法和装置

    公开(公告)号：US07193207B1

    公开(公告)日：2007-03-20

    申请号：US10089963

    申请日：2000-10-16

    Applicant: Li Ding ,  James Edward Nuttall

    Inventor： Li Ding ,  James Edward Nuttall

    IPC: H01J49/42

    CPC classification number: H01J49/427 ,  H01J49/022 ,  H01J49/4295

    Abstract: A digital drive apparatus (FIG. 3) for quadrupole device such as a quadrupole ion trap has a digital signal generator (11, 13, 14; 24, 25, 26) and a switching arrangement (16, 17) which alternately switches between high and low voltage levels (V1, V2) to generate a rectangular wave drive voltage. A dipole excitation voltage is also supplied to the quadrupole device to excite resonant oscillatory motion of ions.

    Abstract translation: 用于诸如四极离子阱的四极装置的数字驱动装置（图3）具有数字信号发生器（11,13,14; 24,25,26）和切换装置（16,17），其交替地在高 和低电压电平（V 1，V 2），以产生矩形波驱动电压。 也向四极装置提供偶极激发电压以激发离子的共振振荡运动。

    Determining equivalent waveforms for distorted waveforms
    117.
    发明申请
    Determining equivalent waveforms for distorted waveforms 有权
    确定失真波形的等效波形

    公开(公告)号：US20060200784A1

    公开(公告)日：2006-09-07

    申请号：US11071121

    申请日：2005-03-02

    Applicant: Li Ding ,  Peivand Fallah-Tehrani ,  Alireza Kasnavi

    Inventor： Li Ding ,  Peivand Fallah-Tehrani ,  Alireza Kasnavi

    IPC: G06F17/50

    CPC classification number: G06F17/5036 ,  G06F17/5031

    Abstract: An equivalent waveform for a distorted waveform used in timing and signal integrity analysis in the design of an integrated circuit is automatically generated. The equivalent waveform is produced by calculating the transition quantity of a first non-distorted waveform. The transition quantity is the amount of transition of the first non-distorted waveform that is required for the cell to produce an output waveform with a predetermined end voltage. The end point of the transition period for the distorted waveform is then determined based on when the distorted waveform has accumulated the same transition quantity. The equivalent waveform can then be formed by computing a second non-distorted waveform such that the end point of the transition period for the second non-distorted waveform coincides with the end point of the transition period for the distorted waveform.

    Abstract translation: 自动生成在集成电路设计中用于定时和信号完整性分析的失真波形的等效波形。 通过计算第一非失真波形的转移量来产生等效波形。 转换量是单元格产生具有预定端电压的输出波形所需的第一非失真波形的转变量。 然后，基于失真波形累积相同过渡量的时间来确定失真波形的转换周期的终点。 然后可以通过计算第二非失真波形来形成等效波形，使得第二非失真波形的转换周期的终点与失真波形的过渡周期的终点重合。

    Method and apparatus for ejecting ions from a quadrupole ion trap
    120.
    发明授权
    Method and apparatus for ejecting ions from a quadrupole ion trap 有权
    从四极离子阱排出离子的方法和装置

    公开(公告)号：US06900433B2

    公开(公告)日：2005-05-31

    申请号：US10451579

    申请日：2001-11-29

    Applicant: Li Ding

    Inventor： Li Ding

    IPC: H01J49/42

    CPC classification number: H01J49/424 ,  H01J49/427

    Abstract: A method for ejecting ions from a quadrupole ion trap includes creating a digital control signal, using the digital control signal to control the timing of a switch unit to generate a time-varying rectangular wave voltage, supplying the rectangular wave voltage to the ion trap to trap ions in a predetermined range of mass-to-charge ratio, and varying the duty cycle of every nth wave of the rectangular wave voltage (where n is an integer greater than 1) to cause ejection of ions having a predetermined mass-to-charge ratio. The method can be used for analysis of mass-to-charge ratio by adjusting the frequency of the rectangular wave voltage to select a starting point for scanning mass-to-charge ratio, and then varying the frequency while the duty cycle is being varied to cause ejection of trapped ions, in sequence, according to mass-to-charge ratio.

    Abstract translation: 用于从四极离子阱中排出离子的方法包括：使用数字控制信号产生数字控制信号，以控制开关单元的定时以产生时变矩形波电压，将矩形波电压提供给离子阱至 在预定的质荷比范围内捕获离子，并且改变矩形波电压（其中n是大于1的整数）的每第n波的占空比，以使得具有预定质量 - 充电比例。 该方法可用于通过调整矩形波电压的频率来选择用于扫描质荷比的起始点，然后在占空比变化到 根据质荷比，依次排出捕获的离子。

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