Systems and methods for quantifying an analyte extracted from a sample

    公开(公告)号:US10269550B2

    公开(公告)日:2019-04-23

    申请号:US15064865

    申请日:2016-03-09

    Abstract: The invention generally relates to systems and methods for quantifying an analyte extracted from a sample. In certain embodiments, the invention provides methods that involve introducing a solvent into a capillary, introducing the capillary into a vessel including a sample such that a portion of the sample is introduced into the capillary, moving the sample and the solvent within the capillary to induce circulation within the sample and the solvent, thereby causing the analyte to be extracted from the sample and into the solvent, analyzing the analyte that has been extracted from the sample, and quantifying the analyte. In certain embodiments, the quantifying step is performed without knowledge of a volume of the sample and/or solvent.

    RARE EVENT DETECTION USING MASS TAGS
    119.
    发明申请
    RARE EVENT DETECTION USING MASS TAGS 审中-公开
    使用大量标签的罕见事件检测

    公开(公告)号:US20160086781A1

    公开(公告)日:2016-03-24

    申请号:US14862517

    申请日:2015-09-23

    CPC classification number: G01N33/58 G01N33/574 G01N2458/15 H01J49/00

    Abstract: The invention generally relates to methods for rare event detection using mass tags. In certain embodiments, the invention provides methods for detecting a target analyte in a sample that involve conducting an assay that specifically associates a mass tag with a target analyte in a sample, generating ions of the mass tag, and analyzing the generated ions of the mass tag, thereby detecting the target analyte from the sample.

    Abstract translation: 本发明一般涉及使用质量标签进行罕见事件检测的方法。 在某些实施方案中,本发明提供了用于检测样品中的目标分析物的方法,所述方法涉及进行将质谱标签与样品中的目标分析物特异性结合的测定物,产生质量标签的离子,并且分析质量的所产生的离子 标签,从而从样品中检测目标分析物。

    SYSTEMS AND METHODS FOR ANALYZING AN EXTRACTED SAMPLE
    120.
    发明申请
    SYSTEMS AND METHODS FOR ANALYZING AN EXTRACTED SAMPLE 有权
    用于分析提取样品的系统和方法

    公开(公告)号:US20150325423A1

    公开(公告)日:2015-11-12

    申请号:US14426591

    申请日:2014-01-10

    Abstract: The invention generally relates to systems for analyzing a sample and methods of use thereof. In certain aspects, the invention provides systems that include an ionization probe and a mass analyzer. The probe includes a hollow body that has a distal tip. The probe also includes a substrate that is at least partially disposed within the body and positioned prior to the distal tip so that sample extracted from the substrate flows into the body prior to exiting the distal tip. The probe also includes an electrode that operably interacts with sample extracted from the substrate.

    Abstract translation: 本发明一般涉及用于分析样品的系统及其使用方法。 在某些方面,本发明提供了包括电离探针和质量分析器的系统。 探针包括具有远端的中空体。 探针还包括至少部分地设置在体内并且定位在远侧末端之前的基底,使得从基底抽出的样品在离开远侧末端之前流入体内。 探针还包括与从衬底提取的样品可操作地相互作用的电极。

Patent Agency Ranking