公开(公告)号：US09962703B2

公开(公告)日：2018-05-08

申请号：US15487956

申请日：2017-04-14

申请人： CUE INC.

发明人： Ayub Khattak ,  Clinton Sever ,  Paul Nelson ,  Ryan Cooper ,  Thomas Congdon ,  Justin Demartino ,  Raphael Shapiro ,  Mark Duncan

IPC分类号： G01N31/22 ,  B01L3/00 ,  B05D3/00 ,  C12Q1/68 ,  F16K99/00 ,  G01N27/28 ,  G01N27/327 ,  G01N33/543 ,  G01N33/58 ,  G01N35/00 ,  H04M1/725 ,  B01L7/00 ,  G01N1/02 ,  G01N21/78 ,  G01N35/10

CPC分类号： B01L3/508 ,  B01F11/0266 ,  B01L3/5027 ,  B01L3/502715 ,  B01L3/502723 ,  B01L3/502738 ,  B01L3/5029 ,  B01L7/52 ,  B01L2200/025 ,  B01L2200/026 ,  B01L2200/027 ,  B01L2200/028 ,  B01L2200/0668 ,  B01L2200/0684 ,  B01L2200/0689 ,  B01L2200/087 ,  B01L2200/10 ,  B01L2200/16 ,  B01L2300/023 ,  B01L2300/025 ,  B01L2300/04 ,  B01L2300/044 ,  B01L2300/06 ,  B01L2300/0627 ,  B01L2300/0645 ,  B01L2300/0681 ,  B01L2300/0816 ,  B01L2300/0838 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2300/087 ,  B01L2300/12 ,  B01L2300/161 ,  B01L2300/1827 ,  B01L2400/0406 ,  B01L2400/0439 ,  B01L2400/0487 ,  B01L2400/0677 ,  B01L2400/0683 ,  B05D3/002 ,  B05D2518/00 ,  C12Q1/6825 ,  F16K99/0032 ,  F16K99/0036 ,  F16K2099/0084 ,  G01N1/02 ,  G01N21/78 ,  G01N27/28 ,  G01N27/3271 ,  G01N27/3272 ,  G01N27/3273 ,  G01N33/54306 ,  G01N33/54326 ,  G01N33/54333 ,  G01N33/54366 ,  G01N33/54373 ,  G01N33/581 ,  G01N35/00029 ,  G01N35/0098 ,  G01N35/1095 ,  G01N2001/027 ,  G01N2001/028 ,  G01N2035/00277 ,  G01N2035/00554 ,  G01N2458/30 ,  H04M1/72527 ,  Y10T137/1797

摘要： Devices, systems, and methods for detecting molecules of interest within a collected sample are described herein. In certain embodiments, self-contained sample analysis systems are disclosed, which include a reusable reader component, a disposable cartridge component, and a disposable sample collection component. The reader component may communicate with a remote computing device for the digital transmission of test protocols and test results. In various disclosed embodiments, the systems, components, and methods are configured to identify the presence, absence, and/or quantity of particular nucleic acids, proteins, or other analytes of interest, for example, in order to test for the presence of one or more pathogens or contaminants in a sample.

公开(公告)号：US09952244B2

公开(公告)日：2018-04-24

申请号：US15182900

申请日：2016-06-15

申请人： Roche Diagnostics Operations, Inc.

发明人： Walter Berberich ,  Julian Baumgart ,  Richard-Paul Daisley ,  Dominik Strzempek ,  Stefan Soentges

IPC分类号： G01N35/04 ,  G01N35/10 ,  G01N35/02 ,  B01L9/00 ,  G01N35/00

CPC分类号： G01N35/10 ,  B01L9/543 ,  G01N35/02 ,  G01N35/04 ,  G01N2035/00277 ,  G01N2035/0465

摘要： A device and method for handling racks of disposable pipette tips in a laboratory automation system are presented. The device comprises a guide rail for guiding racks from a loading region (I) to a supply region (II). The loading region (I) is accessible by a user or a loading device for loading a rack on the guide rail. A plurality of disposable pipette tips stored in a supplying rack located in the supply region (II) is accessible by a delivering device for delivering at least one selected one of the plurality of disposable pipette tips to a pipetting system. The device comprises at least one moveable element, which is controllably moveable by a driving device for selectively enabling or disabling a removal of the supplying rack from the supply region (II). A laboratory automation system comprising such a device and/or for carrying out the method are also presented.

公开(公告)号：US20170343571A1

公开(公告)日：2017-11-30

申请号：US15681255

申请日：2017-08-18

申请人： Ventana Medical Systems, Inc.

发明人： Joshua Harrison ,  Benjamin James ,  Matthew Ketterer

IPC分类号： G01N35/00 ,  G01N33/487 ,  G01N1/31 ,  B01L9/00 ,  G02B21/34

CPC分类号： G01N35/00029 ,  B01L9/52 ,  B01L2200/025 ,  B01L2200/141 ,  B01L2200/143 ,  B01L2300/0848 ,  B01L2300/0858 ,  G01N1/312 ,  G01N33/48757 ,  G01N2035/00039 ,  G01N2035/00089 ,  G01N2035/00138 ,  G01N2035/00277 ,  G02B21/34

摘要： Devices and methods for providing and dispensing opposables onto slides are provided in which magazines loaded with opposables include retention arms to reduce movement of the opposables during shipment and processing and to reduce or eliminate contamination.

公开(公告)号：US20170336427A1

公开(公告)日：2017-11-23

申请号：US15602082

申请日：2017-05-22

申请人： Sentinel Monitoring Systems, Inc.

发明人： Terry D. Long ,  Steven J. Blomquist ,  Richard Vercillo ,  William Puent

IPC分类号： G01N35/00 ,  G01N35/10

CPC分类号： G01N35/00584 ,  G01N35/1004 ,  G01N35/1081 ,  G01N2035/00277

摘要： An online liquid autosampler may include a pipette, a depyrogenation system, a sample source, and a movement system. The depyrogenation system may be configured to selectively depyrogenate the pipette. The sample source may be configured to provide a liquid to be sampled to the pipette. The movement system may be coupled to one or more of the pipette, the depyrogenation system, or the sample source. The movement system may be configured to: position the pipette within the depyrogenation system for depyrogenation; position a tip of the pipette within the sample source to aspirate a sample of the liquid from the sample source; and position the pipette to dispense an aliquot of the sample of the liquid into an aliquot sample target.

公开(公告)号：US20170234901A1

公开(公告)日：2017-08-17

申请号：US15427334

申请日：2017-02-08

申请人： Cytoskeleton, Inc.

发明人： Ashley Middleton-Davis ,  Kim Middleton-Davis

IPC分类号： G01N35/10 ,  G01N35/00 ,  B01L3/00 ,  G01N33/543

CPC分类号： G01N35/1002 ,  B01L3/52 ,  B01L9/52 ,  B01L99/00 ,  B01L2200/141 ,  B01L2200/16 ,  B01L2300/023 ,  B01L2400/0457 ,  B01L2400/0487 ,  G01N33/5302 ,  G01N33/54366 ,  G01N35/00 ,  G01N35/00722 ,  G01N35/0092 ,  G01N2035/00277

摘要： The present disclosure provides devices which deliver fluids from several reservoirs to a reaction vessel and eventually to a waste chamber in a predetermined schedule. The device provides improved simplicity while improving operational robustness and flexibility.

公开(公告)号：US20170234900A1

公开(公告)日：2017-08-17

申请号：US15583319

申请日：2017-05-01

申请人： SnapLab Technologies, LLC

发明人： Justin Briggs

IPC分类号： G01N35/00 ,  B01L3/00

CPC分类号： G01N35/00871 ,  B01L3/508 ,  B01L3/5457 ,  B01L2200/025 ,  B01L2200/026 ,  B01L2300/041 ,  B01L2300/046 ,  B01L2300/0858 ,  G01N35/00732 ,  G01N2035/00277 ,  G01N2035/00801 ,  G01N2035/00831 ,  G01N2035/00851 ,  G01N2035/00881 ,  G01N2035/0405 ,  Y10T436/11

摘要： A sample vessel assembly, comprising a base member including a base flange having first and second opposing surfaces, first and second sides intersecting with one another; and a first sidewall extending from the first surface at a distance from the first and second sides; and a lid member, including: a lid flange having third and fourth opposing surfaces, third and fourth sides intersecting with one another; and a second sidewall extending from the third surface at a distance from the third and fourth sides, the second sidewall engageable with the first sidewall such that the first surface of the base flange and the third surface of the lid flange are in an opposing spaced-apart relationship with one another and such that the first and second sidewalls cooperate with one another to define a sample chamber. Further disclosed is a method for automated analysis of samples in a sample vessel assembly.

公开(公告)号：US09709585B2

公开(公告)日：2017-07-18

申请号：US14577379

申请日：2014-12-19

申请人： Hitachi High-Technologies Corporation

发明人： Mitsuru Oonuma ,  Yoko Sato ,  Hiroyuki Noda ,  Shinji Azuma ,  Naoto Tsujimura

IPC分类号： B65G21/08 ,  B65G21/00 ,  G01N35/04 ,  G01N35/00

CPC分类号： G01N35/04 ,  B65G21/08 ,  G01N2035/00277 ,  G01N2035/00287 ,  G01N2035/00326 ,  G01N2035/0467

摘要： A transport line cover with excellent workability that can be operated by an operator even with one hand. Proposed is a transport line cover that includes a cover body adapted to cover an opening at a top of a sample transport apparatus, the sample transport apparatus accommodating a plurality of transport lines that extend in one direction; and a first groove formed on an upper face of the cover body, the first groove extending from one short side to another short side of the cover body. A lower end of a long-side side face of the cover body is located at a level below a bottom face of the first groove.

公开(公告)号：US09651198B2

公开(公告)日：2017-05-16

申请号：US14387204

申请日：2013-03-21

申请人： Mark Edwards ,  Aarti Kriplani ,  Alan R. Toth ,  Ruairi Cunningham

发明人： Mark Edwards ,  Aarti Kriplani ,  Alan R. Toth ,  Ruairi Cunningham

IPC分类号： F17D1/08 ,  B32B37/16 ,  B32B38/00 ,  B32B38/10 ,  B32B38/16 ,  B01L3/00 ,  F16L11/04 ,  G01N35/10 ,  G01N35/00 ,  A61M39/08

CPC分类号： F17D1/08 ,  A61M39/08 ,  B01L3/561 ,  B01L2200/12 ,  B01L2300/165 ,  B32B37/16 ,  B32B38/0036 ,  B32B38/10 ,  B32B38/162 ,  B32B38/164 ,  B32B2386/00 ,  B32B2597/00 ,  F16L11/04 ,  G01N35/10 ,  G01N2035/00277 ,  Y10T137/8593 ,  Y10T428/139

摘要： The present invention discloses a section of tubing including a fluoropolmer tubular body which has an interior surface defining a fluid passage through the tubular body. At least a first portion of the interior surface has a first hydrophobicity which is less than that of the remainder of the tubular body. At least a first portion of the interior surface can have a molar ratio of fluorine to oxygen of no greater than 30 to 1. Products can include the tubular bodies of the present invention attachable to fluid processing instruments such as immunodiagnostic instruments. The present invention also discloses methods for manufacturing the disclosed tubular bodies.

公开(公告)号：US09636676B2

公开(公告)日：2017-05-02

申请号：US15172077

申请日：2016-06-02

申请人： CUE INC.

发明人： Clinton Sever ,  Ayub Khattak

IPC分类号： F16K17/14 ,  B01L3/00 ,  G01N35/08 ,  G01N33/543 ,  H04M1/725 ,  G01N35/00 ,  G01N27/28 ,  B05D3/00 ,  F16K99/00 ,  C12Q1/68 ,  G01N33/58 ,  G01N1/02 ,  G01N35/10 ,  G01N21/78 ,  G01N27/327

CPC分类号： B01L3/502715 ,  B01L3/5027 ,  B01L3/502723 ,  B01L3/502738 ,  B01L3/5029 ,  B01L2200/025 ,  B01L2200/026 ,  B01L2200/027 ,  B01L2200/028 ,  B01L2200/04 ,  B01L2200/0668 ,  B01L2200/0684 ,  B01L2200/0689 ,  B01L2200/087 ,  B01L2200/10 ,  B01L2200/16 ,  B01L2300/023 ,  B01L2300/025 ,  B01L2300/04 ,  B01L2300/044 ,  B01L2300/06 ,  B01L2300/0627 ,  B01L2300/0645 ,  B01L2300/0681 ,  B01L2300/0816 ,  B01L2300/0838 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2300/087 ,  B01L2300/12 ,  B01L2300/161 ,  B01L2300/1827 ,  B01L2400/0406 ,  B01L2400/0487 ,  B01L2400/0677 ,  B01L2400/0683 ,  B05D3/002 ,  B05D2518/00 ,  C12Q1/6825 ,  F16K99/0032 ,  F16K99/0036 ,  F16K2099/0084 ,  G01N1/02 ,  G01N21/78 ,  G01N27/28 ,  G01N27/3271 ,  G01N27/3272 ,  G01N27/3273 ,  G01N33/54306 ,  G01N33/54326 ,  G01N33/54333 ,  G01N33/54366 ,  G01N33/54373 ,  G01N33/5438 ,  G01N33/581 ,  G01N35/00029 ,  G01N35/0098 ,  G01N35/08 ,  G01N35/1095 ,  G01N2001/027 ,  G01N2001/028 ,  G01N2035/00277 ,  G01N2035/00564 ,  G01N2458/30 ,  H04M1/72527 ,  H04M1/7253 ,  Y10T137/1797

摘要： Devices, systems, and methods for detecting molecules of interest within a collected sample are described herein. In certain embodiments, self-contained sample analysis systems are disclosed, which include a reusable reader component, a disposable cartridge component, and a disposable sample collection component. In some embodiments, the reader component communicates with a remote computing device for the digital transmission of test protocols and test results. In various disclosed embodiments, the systems, components, and methods are configured to identify the presence, absence, and/or quantity of particular nucleic acids, proteins, or other analytes of interest, for example, in order to test for the presence of one or more pathogens or contaminants in a sample.

公开(公告)号：US20170080421A1

公开(公告)日：2017-03-23

申请号：US15368249

申请日：2016-12-02

申请人： CUE INC.

发明人： Ayub Khattak ,  Clinton Sever

IPC分类号： B01L3/00 ,  G01N1/02 ,  F16K99/00 ,  G01N33/58 ,  G01N35/00 ,  G01N35/10 ,  C12Q1/68 ,  G01N33/543

CPC分类号： B01L3/502715 ,  B01L3/5027 ,  B01L3/502723 ,  B01L3/502738 ,  B01L3/5029 ,  B01L2200/025 ,  B01L2200/026 ,  B01L2200/027 ,  B01L2200/028 ,  B01L2200/04 ,  B01L2200/0668 ,  B01L2200/0684 ,  B01L2200/0689 ,  B01L2200/087 ,  B01L2200/10 ,  B01L2200/16 ,  B01L2300/023 ,  B01L2300/025 ,  B01L2300/04 ,  B01L2300/044 ,  B01L2300/06 ,  B01L2300/0627 ,  B01L2300/0645 ,  B01L2300/0681 ,  B01L2300/0816 ,  B01L2300/0838 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2300/087 ,  B01L2300/12 ,  B01L2300/161 ,  B01L2300/1827 ,  B01L2400/0406 ,  B01L2400/0487 ,  B01L2400/0677 ,  B01L2400/0683 ,  B05D3/002 ,  B05D2518/00 ,  C12Q1/6825 ,  F16K99/0032 ,  F16K99/0036 ,  F16K2099/0084 ,  G01N1/02 ,  G01N21/78 ,  G01N27/28 ,  G01N27/3271 ,  G01N27/3272 ,  G01N27/3273 ,  G01N33/54306 ,  G01N33/54326 ,  G01N33/54333 ,  G01N33/54366 ,  G01N33/54373 ,  G01N33/5438 ,  G01N33/581 ,  G01N35/00029 ,  G01N35/0098 ,  G01N35/08 ,  G01N35/1095 ,  G01N2001/027 ,  G01N2001/028 ,  G01N2035/00277 ,  G01N2035/00564 ,  G01N2458/30 ,  H04M1/72527 ,  H04M1/7253 ,  Y10T137/1797

摘要： Devices, systems, and methods for detecting molecules of interest within a collected sample are described herein. In certain embodiments, self-contained sample analysis systems are disclosed, which include a reusable reader component, a disposable cartridge component, and a disposable sample collection component. In some embodiments, the reader component communicates with a remote computing device for the digital transmission of test protocols and test results. In various disclosed embodiments, the systems, components, and methods are configured to identify the presence, absence, and/or quantity of particular nucleic acids, proteins, or other analytes of interest, for example, in order to test for the presence of one or more pathogens or contaminants in a sample.