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    Treating body tissue by applying energy and substances with a retractable catheter and contained cooling element
    184.
    发明授权
    Treating body tissue by applying energy and substances with a retractable catheter and contained cooling element 有权
    通过用可伸缩导管施加能量和物质来处理身体组织，并容纳冷却元件

    公开(公告)号：US06425853B1

    公开(公告)日：2002-07-30

    申请号：US09339473

    申请日：1999-06-23

    Applicant: Stuart D. Edwards

    Inventor： Stuart D. Edwards

    IPC: A61F200

    CPC classification number: A61B18/1477 ,  A61B18/1485 ,  A61B2018/00553

    Abstract: The invention provides a method and system for treatment for body structures, especially internal body structures involving unwanted features or other disorders, that does not require relatively invasive surgery, and is not subject to other drawbacks noted with regard to the known art. A relatively minimally invasive catheter including a contained cooling element is inserted into the body. The distal and proximal end of the catheter are extended or retracted or some combination thereof so as to achieve optimal delivery of treatment. Treatment of the body structures is applied using the electrodes embedded in the cooling element, and the unwanted features or disorders are relatively cured using the applied treatments. In a preferred embodiment, the applied treatments can include application of energy or substances, including application (such as of radio frequency energy, microwave energy, or laser or other electromagnetic energy) or substances (such as collagen or other bulking, plumping, or shaping agents; saline or other energy-receiving electrolytes; astringents or other debulking, reducing, or shaping agents; antibiotics or other bioactive, chemoactive, or radioactive compounds). In a preferred embodiment, more than one applied treatment can be performed, either in conjunction, in parallel, or seriatim, so as to achieve a combined effect more substantial than any one individual such applied treatment.

    Abstract translation: 本发明提供了一种用于身体结构的治疗方法和系统，特别是涉及不需要的特征或其他疾病的内部身体结构，其不需要相对侵入性的手术，并且不会受到关于已知技术的其他缺点的影响。 将包含冷却元件的相对微创的导管插入体内。 导管的远端和近端延伸或缩回，或其某些组合，以达到治疗的最佳输送。 使用嵌入冷却元件中的电极来施加身体结构的治疗，并且使用所施加的治疗相对固化不想要的特征或障碍。 在优选实施例中，所应用的处理可以包括能量或物质的应用，包括应用（诸如射频能量，微波能量或激光或其它电磁能）或物质（诸如胶原或其它填充，填充或成形 漱口剂或其他减压剂，还原剂或成型剂;抗生素或其他生物活性，化学活性或放射性化合物）。 在一个优选的实施方案中，多个施用的治疗可以结合，并行或连续进行，以便达到比任何一个个体更加实质的组合效果。

    Integrated cardiac mapping and ablation probe
    188.
    发明授权
    Integrated cardiac mapping and ablation probe 失效
    集成心脏图谱和消融探针

    公开(公告)号：US5964753A

    公开(公告)日：1999-10-12

    申请号：US3087

    申请日：1998-01-05

    Applicant: Stuart D. Edwards

    Inventor： Stuart D. Edwards

    IPC: A61B18/14 ,  A61N1/06 ,  A61B17/39 ,  A61N5/02

    CPC classification number: A61N1/06 ,  A61B18/1492 ,  A61B18/1815 ,  A61B2018/0016 ,  A61B2018/00214 ,  A61B2018/00357 ,  A61B2018/00577 ,  A61B2018/00839 ,  A61B2018/1253 ,  A61B2218/002

    Abstract: A probe for cardiac diagnosis and/or treatment has a catheter tube. The distal end of the catheter tube carries first and second electrode elements. The probe includes a mechanism for steering the first electrode element relative to the second electrode element so that the user can move the first electrode element into and out of contact with endocardial tissue without disturbing the contact of the second electrode element with endocardial tissue, even through the two electrode elements are carried on a common catheter tube. The distal end can carry a three dimensional structure having an open interior area. One of electrode elements can be steered through the open interior area of the structure. Electrode elements on the exterior of the structure can be used for surface mapping, while the electrode element inside the structure is steered to ablate tissue.

    Abstract translation: 用于心脏诊断和/或治疗的探针具有导管。 导管管的远端承载第一和第二电极元件。 探针包括用于相对于第二电极元件转向第一电极元件的机构，使得使用者可以将第一电极元件移入和脱离与心内膜组织的接触，而不会干扰第二电极元件与心内膜组织的接触，甚至通过 两个电极元件被携带在公共导管上。 远端可以承载具有敞开内部区域的三维结构。 电极元件之一可以通过结构的开放内部区域转向。 结构外部的电极元件可用于表面映射，而结构内的电极元件被转向以消融组织。

    Treating aneurysms by applying hardening/softening agents to hardenable/softenable substances
    189.
    发明授权
    Treating aneurysms by applying hardening/softening agents to hardenable/softenable substances 失效
    通过将硬化/软化剂施用于可硬化/可软化的物质来治疗动脉瘤

    公开(公告)号：US5921954A

    公开(公告)日：1999-07-13

    申请号：US677811

    申请日：1996-07-10

    Applicant: Lawrence G. Mohr, Jr. ,  Stuart D. Edwards

    Inventor： Lawrence G. Mohr, Jr. ,  Stuart D. Edwards

    IPC: A61B18/14 ,  A61F2/82 ,  A61M31/00 ,  A61M29/00

    CPC classification number: A61F2/82 ,  A61B18/1492 ,  A61B2017/003 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00261 ,  A61B2018/0041 ,  A61B2018/00416 ,  A61B2018/00797 ,  A61B2090/3614

    Abstract: A method and system for treating aneurysms by applying RF energy to collagen. A catheter is disposed near the aneurysm and collagen is exuded into or near the aneurysm. RF energy is applied, using the same catheter or a second catheter, to the collagen, causing the collagen to harden and cover the weak region of the blood vessel wall, and providing a base onto which epithelial cells of the blood vessel may grow. The catheter comprises an electrophysiology catheter, including a ring electrode preferably disposed to deliver between about 5 and about 30 watts of RF energy at a frequency preferably between about 450 and about 600 Megahertz, to apply sufficient energy to cause the collagen to harden while avoiding damage to surrounding tissue.

    Abstract translation: 通过向胶原蛋白施加RF能量来治​​疗动脉瘤的方法和系统。 导管位于动脉瘤附近，胶原蛋白渗出到动脉瘤内或附近。 使用相同的导管或第二导管将RF能量施加到胶原，使胶原蛋白硬化并覆盖血管壁的弱区域，并提供血管上皮细胞生长的基底。 导管包括电生理学导管，其包括环电极，优选设置为以大约450和大约600兆赫之间的频率递送约5至约30瓦的RF能量，以施加足够的能量以使胶原蛋白硬化，同时避免损伤 到周围的组织。

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